LOCUS       NM_173337                409 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus calcium/calmodulin-dependent protein kinase II
            inhibitor 1 (Camk2n1), mRNA.
ACCESSION   NM_173337
VERSION     NM_173337.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Astudillo,D., Karmelic,D., Casas,B.S., Otmakhov,N., Palma,V. and
            Sanhueza,M.
  TITLE     CaMKII inhibitor 1 (CaMK2N1) mRNA is upregulated following LTP
            induction in hippocampal slices
  JOURNAL   Synapse 74 (10), e22158 (2020)
   PUBMED   32320502
  REMARK    GeneRIF: CaMKII inhibitor 1 (CaMK2N1) mRNA is upregulated following
            LTP induction in hippocampal slices.
REFERENCE   2  (bases 1 to 409)
  AUTHORS   Carneiro,I., Quintela-Vieira,F., Lobo,J., Moreira-Barbosa,C.,
            Menezes,F.D., Martins,A.T., Oliveira,J., Silva,R., Jeronimo,C. and
            Henrique,R.
  TITLE     Expression of EMT-Related Genes CAMK2N1 and WNT5A is increased in
            Locally Invasive and Metastatic Prostate Cancer
  JOURNAL   J Cancer 10 (24), 5915-5925 (2019)
   PUBMED   31762801
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 409)
  AUTHORS   Alfazema,N., Barrier,M., de Proce,S.M., Menzies,R.I., Carter,R.,
            Stewart,K., Diaz,A.G., Moyon,B., Webster,Z., Bellamy,C.O.C.,
            Arends,M.J., Stimson,R.H., Morton,N.M., Aitman,T.J. and Coan,P.M.
  TITLE     Camk2n1 Is a Negative Regulator of Blood Pressure, Left Ventricular
            Mass, Insulin Sensitivity, and Promotes Adiposity
  JOURNAL   Hypertension 74 (3), 687-696 (2019)
   PUBMED   31327268
REFERENCE   4  (bases 1 to 409)
  AUTHORS   Li,N., Nan,C.C., Zhong,X.Y., Weng,J.Q., Fan,H.D., Sun,H.P.,
            Tang,S., Shi,L. and Huang,S.X.
  TITLE     miR-182-5p Promotes Growth in Oral Squamous Cell Carcinoma by
            Inhibiting CAMK2N1
  JOURNAL   Cell Physiol Biochem 49 (4), 1329-1341 (2018)
   PUBMED   30205384
REFERENCE   5  (bases 1 to 409)
  AUTHORS   de Paiva Lima,C., da Silva E Silva,D.A., Damasceno,S.,
            Ribeiro,A.F., Rocha,C.S., Berenguer de Matos,A.H., Correia,D.,
            Boerngen-Lacerda,R. and Brunialti Godard,A.L.
  TITLE     Loss of control over the ethanol consumption: differential
            transcriptional regulation in prefrontal cortex
  JOURNAL   J Neurogenet 31 (3), 170-177 (2017)
   PUBMED   28714806
REFERENCE   6  (bases 1 to 409)
  AUTHORS   Lucchesi,W., Mizuno,K. and Giese,K.P.
  TITLE     Novel insights into CaMKII function and regulation during memory
            formation
  JOURNAL   Brain Res Bull 85 (1-2), 2-8 (2011)
   PUBMED   21070840
  REMARK    Review article
REFERENCE   7  (bases 1 to 409)
  AUTHORS   Skelding,K.A., Rostas,J.A. and Verrills,N.M.
  TITLE     Controlling the cell cycle: the role of
            calcium/calmodulin-stimulated protein kinases I and II
  JOURNAL   Cell Cycle 10 (4), 631-639 (2011)
   PUBMED   21301225
  REMARK    Review article
REFERENCE   8  (bases 1 to 409)
  AUTHORS   Saha,S., Datta,K. and Rangarajan,P.
  TITLE     Characterization of mouse neuronal Ca2+/calmodulin kinase II
            inhibitor alpha
  JOURNAL   Brain Res 1148, 38-42 (2007)
   PUBMED   17350603
REFERENCE   9  (bases 1 to 409)
  AUTHORS   Saha,S., Ramanathan,A. and Rangarajan,P.N.
  TITLE     Regulation of Ca2+/calmodulin kinase II inhibitor alpha
            (CaMKIINalpha) in virus-infected mouse brain
  JOURNAL   Biochem Biophys Res Commun 350 (2), 444-449 (2006)
   PUBMED   17010311
REFERENCE   10 (bases 1 to 409)
  AUTHORS   Chang,B.H., Mukherji,S. and Soderling,T.R.
  TITLE     Calcium/calmodulin-dependent protein kinase II inhibitor protein:
            localization of isoforms in rat brain
  JOURNAL   Neuroscience 102 (4), 767-777 (2001)
   PUBMED   11182241
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF271156.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF271156.1, AA817703.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..409
                     /gene="Camk2n1"
                     /note="calcium/calmodulin-dependent protein kinase II
                     inhibitor 1"
                     /db_xref="GeneID:287005"
                     /db_xref="RGD:708430"
     exon            1..175
                     /gene="Camk2n1"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..246
                     /gene="Camk2n1"
                     /note="caMKIINalpha; caM-KIINalpha;
                     calcium/calmodulin-dependent protein kinase II inhibitor
                     alpha; CaM-kinase II inhibitor alpha"
                     /codon_start=1
                     /product="calcium/calmodulin-dependent protein kinase II
                     inhibitor 1"
                     /protein_id="NP_775459.1"
                     /db_xref="GeneID:287005"
                     /db_xref="RGD:708430"
                     /translation="MSEVLPYGDEKLSPYGDGGDVGQIFSCRLQDTNNFFGAGQSKRP
                     PKLGQIGRSKRVVIEDDRIDDVLKTMTDKAPPGV"
     exon            176..409
                     /gene="Camk2n1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgcgacca tgtcggaggt gctgccctac ggcgacgaga agctgagccc ctacggcgac
       61 ggcggcgacg tgggccagat cttctcgtgc cgcctgcagg acaccaacaa cttcttcggc
      121 gccgggcaga gcaagcggcc gcccaagctg ggccagatcg gccggagcaa gcgcgttgtt
      181 attgaagatg ataggatcga tgacgtgctg aaaaccatga ccgacaaggc acctcctggt
      241 gtctaactgc ccccaaagac aatgtgttga gggaaggaat aagaagagtg gcgggctgtg
      301 acagttactg acaaaaagca tgaggaggag aaagcacttt ggaatttatt attagcttgc
      361 tacctacgat gaaatcgaca acctgtgtct caagtcaggc cgggagaca
//
