LOCUS       NM_138513                947 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus calcitonin-related polypeptide, beta (Calcb),
            mRNA.
ACCESSION   NM_138513
VERSION     NM_138513.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 947)
  AUTHORS   Dong YL, Vegiraju S, Gangula PR, Kondapaka SB, Wimalawansa SJ and
            Yallampalli C.
  TITLE     Expression and regulation of calcitonin gene-related Peptide
            receptor in rat placentas
  JOURNAL   Biol Reprod 67 (4), 1321-1326 (2002)
   PUBMED   12297551
  REMARK    GeneRIF: results indicate that calcitonin gene-related peptide-B
            receptors are present in rat placenta and that receptor levels are
            higher with gestational age and lower at term labor (Calcb)
            Erratum:[Biol Reprod. 2002 Dec;67(6):1996.]
REFERENCE   2  (bases 1 to 947)
  AUTHORS   Amara,S.G., Arriza,J.L., Leff,S.E., Swanson,L.W., Evans,R.M. and
            Rosenfeld,M.G.
  TITLE     Expression in brain of a messenger RNA encoding a novel
            neuropeptide homologous to calcitonin gene-related peptide
  JOURNAL   Science 229 (4718), 1094-1097 (1985)
   PUBMED   2994212
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000043.1.
            
            [WARNING] On Mar 25, 2024 this sequence was replaced by
            NM_138513.3.
            
            On Feb 10, 2021 this sequence version replaced NM_138513.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB616058.1, CB584926.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN13663614, SAMN16418971
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                JACYVU010000043.1  6339841-6339890
            51-147              JACYVU010000043.1  6340921-6341017
            148-303             JACYVU010000043.1  6341260-6341415
            304-488             JACYVU010000043.1  6343353-6343537
            489-947             JACYVU010000043.1  6344259-6344717
FEATURES             Location/Qualifiers
     source          1..947
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q34"
     gene            1..947
                     /gene="Calcb"
                     /note="calcitonin-related polypeptide, beta"
                     /db_xref="GeneID:171519"
                     /db_xref="RGD:620997"
     exon            1..50
                     /gene="Calcb"
                     /inference="alignment:Splign:2.1.0"
     exon            51..147
                     /gene="Calcb"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..592
                     /gene="Calcb"
                     /note="CGRP-II; beta-type CGRP; calcitonin gene-related
                     peptide II"
                     /codon_start=1
                     /product="calcitonin gene-related peptide 2"
                     /protein_id="NP_612522.2"
                     /db_xref="GeneID:171519"
                     /db_xref="RGD:620997"
                     /translation="MWVLCLASSLQAAPFRSALESSLDLGTLSDQEKHLLLAALIQDY
                     EQKARKLEQEEQETEGSRKGSSSSVISQKRSCKHRHLCDPSAGRLAEQVGRCGEGQLC
                     AHQCGLQSLWPAPQGTFGSEELTLQEEGYIKLNSPRLLIFINNNPMRRPHGRCVCLHP
                     ERY"
     exon            148..303
                     /gene="Calcb"
                     /inference="alignment:Splign:2.1.0"
     exon            304..488
                     /gene="Calcb"
                     /inference="alignment:Splign:2.1.0"
     exon            489..947
                     /gene="Calcb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttctggagt ggacacttcg ctctcactgt tccaacactc ggactaccag agacaccatg
       61 gacttctgga agttctttcc tttttctggc tctcagcagc atgtgggtcc tgtgcctggc
      121 cagcagcctc caggcagccc ctttcaggtc agctttggag agcagcctag acctgggcac
      181 cctcagcgac caggaaaaac acctcttgct tgctgcattg atacaggact atgaacagaa
      241 ggccaggaag ctggaacagg aggagcaaga gactgagggc tccaggaaag gctcctcctc
      301 cagtgtcatt tcccagaaga gatcctgcaa acaccgccac ctgtgtgacc catcggctgg
      361 caggcttgct gagcaggtcg ggaggtgtgg tgaaggacaa ctttgtgccc accaatgtgg
      421 gctccaaagc ctttggccgg cgccgcaggg gaccttcggg tctgaggaac taacgctcca
      481 ggaagaaggt tacataaagt tgaactcacc acgcctatta atttttatta acaacaaccc
      541 tatgagaagg ccccatggac gatgtgtatg tttgcatcct gaaagatact gagggaaaac
      601 accattgtca cttgagagaa atgaaaccaa gtataaatga gttaattctg tgttcgttgc
      661 atcattttta tactgagtct atggccagtc aaatatgatg gtgtctcctg ctggcatcct
      721 ttgcagcaaa ccaaataggt tctccaagag ccgtccagac gatggtagca gctctggtga
      781 acctcaggga gacgtgatat cactgcctct tgtagccact gggacttgta gtagaggaga
      841 tgctgtgcct tgatgtctca gaacataact gtaaatttat ttaaggaaat gtcaaaattg
      901 taccatttgt gaacttcatc aagattaaaa aacatatttt ggataca
//
