LOCUS       NM_001416001            5673 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus CDK2-associated, cullin domain 1 (Cacul1),
            transcript variant 1, mRNA.
ACCESSION   NM_001416001 XM_006231678
VERSION     NM_001416001.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5673)
  AUTHORS   Kong,Y., Nan,K. and Yin,Y.
  TITLE     Identification and characterization of CAC1 as a novel
            CDK2-associated cullin
  JOURNAL   Cell Cycle 8 (21), 3552-3561 (2009)
   PUBMED   19829063
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 6, 2023 this sequence version replaced XM_006231678.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.7045.1,
                                           SRR26643296.4862.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-657               JAXUCZ010000001.1  269711456-269712112 c
            658-784             JAXUCZ010000001.1  269695156-269695282 c
            785-887             JAXUCZ010000001.1  269694244-269694346 c
            888-983             JAXUCZ010000001.1  269674577-269674672 c
            984-1086            JAXUCZ010000001.1  269672274-269672376 c
            1087-1176           JAXUCZ010000001.1  269666722-269666811 c
            1177-1315           JAXUCZ010000001.1  269663465-269663603 c
            1316-1359           JAXUCZ010000001.1  269657041-269657084 c
            1360-5673           JAXUCZ010000001.1  269652356-269656669 c
FEATURES             Location/Qualifiers
     source          1..5673
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..5673
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /note="CDK2-associated, cullin domain 1"
                     /db_xref="GeneID:365493"
                     /db_xref="RGD:1308127"
     exon            1..657
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     CDS             267..1400
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /note="isoform 1 is encoded by transcript variant 1;
                     CDK2-associated and cullin domain-containing protein 1;
                     uncharacterized protein C10orf46 homolog"
                     /codon_start=1
                     /product="CDK2-associated and cullin domain-containing
                     protein 1 isoform 1"
                     /protein_id="NP_001402930.1"
                     /db_xref="GeneID:365493"
                     /db_xref="RGD:1308127"
                     /translation="MEESMEEEEMLTYEAMMDDQNHNNWEAAVDSFRQPPPAPPLPPP
                     PPPRPSSSIPDPGRELPGGQLLAVHAGSMDRKGLKEGLPMGSPPLSEPNGVIMMLKSC
                     DAAAAVAKAAPAPTPSSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQSP
                     GDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITSHLERVSKELQASPPDLYIERF
                     NIALGQYMGALQSIVPLFIYMNKFYIETKLNRDLKDDLIKLFTEHVAEKHIYSLMPLL
                     LEAQSTPFQVTPSTMANIVKGLYTLRPEWVQMAPTLFSKFIPNILPPAVESELSEYAA
                     QDQKLQRELIQNGFTRGDQSRKRAGDELAYNSPSACASSRGYR"
     exon            658..784
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     exon            785..887
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     exon            888..983
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1086
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1176
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1315
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1359
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..5673
                     /gene="Cacul1"
                     /gene_synonym="RGD1308127"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaagaaact gctgtaaaat gtcgtgaggg acgtcgccgc tttgcggctg cttctctcag
       61 aactagaccc cgggagtgcc caccgcagtc agcggttcct ccggcggagt cgtcctgaca
      121 gaaggcgaga gcactcggcg cgccactgga tttttcgccg cacccgcgag ggctccgggc
      181 gatgtgaact cgaggcggct tctgtgctcc caggcccggg ggctgaggtg ggcaggcagg
      241 tgcctgggaa gccgcggccc ggcgggatgg aggagagtat ggaggaggag gaaatgctca
      301 cctacgaggc aatgatggac gaccagaacc acaacaactg ggaggccgcc gtagacagct
      361 tccgtcagcc cccgcccgcc ccgccgctgc ccccgccgcc gccgccgcgg ccctcgtcgt
      421 ccatcccgga tcctggccga gaactcccgg ggggacagct gctggctgtg catgcgggct
      481 ccatggacag gaagggtctt aaggaggggc tcccgatggg gtctccgccc ttgtcggagc
      541 caaacggggt gattatgatg ttgaagagct gcgacgcagc cgccgcggtg gccaaggcgg
      601 cccctgcccc cacccctagc tccaccatca acatcaacac ctccacctcc aagttcctaa
      661 tgaatgttat aacaattgaa gattataaga gcacatactg gccaaaatta gatggtgcca
      721 tagatcaact tttaacccag agtcctggtg actatatacc tatatcctat gagcagattt
      781 acagttgtgt gtataagtgt gtgtgccagc agcactcaga acagatgtac agtgatctga
      841 ttaaaaaaat aaccagccac ttagagcgag tctccaagga gctgcaggcc agccctccag
      901 acctctatat tgagagattt aatatagctc tgggtcagta tatgggagca ttgcagagca
      961 tcgtgcctct tttcatatat atgaataagt tttacataga aactaagctt aacagagact
     1021 taaaagatga ccttataaaa ctgtttacgg aacatgttgc agagaagcac atttacagcc
     1081 taatgccttt acttttagaa gcccagtcaa caccatttca ggtcacacct tcaactatgg
     1141 caaatattgt gaaaggcctg tacactctca gaccagaatg ggttcagatg gctccgacat
     1201 tgttttctaa gtttattcca aacattctgc ccccagctgt ggaatctgaa ctttctgagt
     1261 acgctgccca agatcaaaag cttcaaagag aactcataca gaacggtttt accagaggtg
     1321 accagtcccg gaagagagct ggagatgagt tggcttacaa cagtccatcc gcttgtgcaa
     1381 gttccagagg gtatagatag tgactgttga actacgtttc tcccgagaga agacacactg
     1441 gagctacaga aactgttcca ggcacagtgg ggcctgcacc actcaggagc tctgtcagag
     1501 gctgttctca gagaggatac cggacttctt tctttgattt tcagttttta aaaacaagaa
     1561 ctaacaaaaa caattgctgc tagactgggg ggtgatttga agtgggacaa tcttttaatc
     1621 tacagagcaa gtgtcttgga gagcggccgt tgctaaaggg aagctcaaca tttgaatcag
     1681 cttcctccag aaatacaaga acgaaagaat cttttttttt ttaaagccct cgtcttgttc
     1741 atttgtggac ttggaacatg gtgtcacatg tcaagatatc tttgctttaa aaccaagcag
     1801 atattacaat acagtgtttt cacccattcc ccaaacaatc tgttttaaat tcagattggt
     1861 ctatgtttag caattagtct tgtggaggaa aatgctaact gctttcacta tcactttccc
     1921 tgtcaattcc cgttttcaac tgtgtgcctt gagctctgtg cactttgcag ctatgtgacc
     1981 atgtcatcaa tctcacgatg cttcaaactg gcccaccaaa gcctctgtat ggctttgtgt
     2041 ttgtagcaga acctgattga gaaaatggaa gcactagagg ctggtcagaa ttcacctggc
     2101 tgtcccagct ctcctgggga ccaactctta ctgagtggtt tccattctgc tatcccctca
     2161 tctgatctca gcttcaagtg gggtggagcc ctgggttagg gctatgatac tgtagagatt
     2221 gcccaacaga gggggttgct cccttggtcc ctctctggat gaatggtttt aaagccaact
     2281 atggtccatc tcattttatt gggtgtattt aatacgaaaa aaggtcagct ctaccctgca
     2341 tctcgtaaac atcatgtttg atatcaagtg caacagggag agtttgcact gttgtttgaa
     2401 ggctcctttc agctgtggta aagttgtatt acccgtttcc tacaccaact gtgctcttta
     2461 gttcttcaca aaagtctgaa gcttatccag ttgtttttca gtaataacaa aactagacat
     2521 agcaaggaaa aagtattttt cttctcaatt ttgcttgaat gtgaagtgag cattagcttt
     2581 gtgctaccag gctccatcag acagtgatgc tgaccattta gagaatgcac ctaatgctac
     2641 tgctaccaat tcagtgggca gtagagttag aagtggaaca ccagggacaa gaacattacc
     2701 cagtagcagt cctgtgtttg taaacaatgt tccaggggag gaatagttaa gggttgacag
     2761 cttgattctt tcaggtactt gtctgcagtt ggtagagttt atggggggtt taattggctc
     2821 attccatttg ggttacattg aaaaaccctg agtagggaca agtgggctct tatggtctgt
     2881 atagcttttt ctgctctaat gtcaagggaa atttttcatt ttatcaaaaa acccagttta
     2941 cttttctgat ggaatgctca ccacaaagtt gtaaatatca tttggaagtg gtttcttcta
     3001 cccagcttta atatttttga caatagtaaa gttggagcat ttcttgaaac ataatagttt
     3061 caagaatagt tcataatagt tgaaacatag tggttccgtg tcttaattat gccctcctgc
     3121 tcccccagga gagagtgctc ttctttctct ccaaaagaac tttccctata aaagcattat
     3181 attaaataaa ttggcattaa agtgggtgct tttgtgttag taactcaaag ttagtcatac
     3241 tcattctgca ttagcacaaa ataggcagag gaaagcctct gaaattctca ttctcagagt
     3301 caaagcctag caccactttg ctggtactga aaggcatggg gaaaatgagt gtgctcctga
     3361 ggactgtgtc ctggtggttt agcaaggctt tacagtttgt aaacttcagg tgaaattgac
     3421 acttcttgtt aattgaagtc tttacagaag tcttaatctc caactacgag gaaataaaat
     3481 ctgttctgcc tcattttgta tttcctggaa atattttctt ttcaagtgta cttgtgctct
     3541 taccagtaca gtttttctac ccctgctgag gactgttttt ctcaatcaga tccttaacag
     3601 tcaaatggta tagatcagtt agtcactgta atatagttga tttggctaga tggctagtat
     3661 ggttttattt gcctaaaagt aggcctttta aaaaaaaaga aaaccaggtg ggttatcttc
     3721 aagtgatggt ttaaaaagta aacggatgat agtgttgaga gaccatgctc attttaaagg
     3781 ttgaccttat gcttagatta tctggtgacc tgctatcata actgcaccct gacctgacaa
     3841 gaatcatttt cctgggggca gaaagtagaa tttagtggca cctaagcagg gttagcaaga
     3901 agaaactcta acttgcattc acaattagta atgatacagt gcattactaa aacttctcag
     3961 tcttttatta caagtcacct gttcccctgt ttgctagaat gaagttggtt tgagtgttgg
     4021 tgagactgca gaggaatgga tgtccctggt catgacactg catgtctcag acctgtctag
     4081 ctgctgcccc cctgtcgttt actttctgtc aggttgcaga tttgcacacg tgaatgattc
     4141 ctcaggaaca gtttgcacac tcctcacctc aatatagtct gtacagacca aacagcatct
     4201 aaggttatca gcacaagagg gttcatacac ctactagcag aggccatgtg agcttgcagg
     4261 caactggttt ctgcaggtaa tgggaagagg agcacatagt gtttgtttaa atgacctccc
     4321 aattctcgct gtaaaccaga gtaagaaacc ttccagatgg tgtattgggg ctgtggtttt
     4381 tgtctgtttt ttcctctttt ctgtttttcc tcatatatgc aagaggaatt gcccaggagc
     4441 taagattcat ctgtttatta agctctgtcc ttaagcatta ttcaatgaag tacactaatc
     4501 tgagataata agaaacaact aaaaagcaaa acaaaaactg cattcggtat ccatctgtta
     4561 gagttcattt tttagtgtgt tcttgagctt tttagcttgg aatatttatt tttatccaag
     4621 tgtagggctc ttaagagggg ggacgttaaa attcaaggtt ggaatgtgac acccttaact
     4681 gacatctgga agaagtattg accttttctg ttggtgactg cttttagtaa tactgtgtaa
     4741 aatgttcgtt tttaccagag gttcaagcag aagtcatagg ggttcataga gaagtggctc
     4801 ttctgtgctt ttgttatcgt gtagaaattt tccttggttt ctgaccccta gactatttgg
     4861 aaggaggtgc ttattctttt ccaaaggaaa tgctccctct ctggtcccct gctgcttagc
     4921 tgcagtcact gcctccttcc tcctgcacta gctggcacct taatttaaac ctccttcctg
     4981 agccagggat gggtctgcct cctgggtgca ggacctgtta ctttacagga ccaatgtctg
     5041 ccatgaagat cttcatttta ggcctgattc cagtgttaga agagtgctgc tggattatac
     5101 ccagggaagt tgtcaacacg gctcttgggt tgagtgattt gttaaaaaaa aaaaaaagaa
     5161 gataaatact ttggttctta catgtttaaa tactgtgatt gtactaaatt cagtgagact
     5221 gggtattctc ttaaaggtgg cagtgttctt ggttcttagt cttacgtcag tgttaacagc
     5281 catcaatttt cagagaaatt acttacttaa acatcaagtc ctgggaaatt ggctcaaaca
     5341 aatgcttata caaaatttgg agatcatgtg caggctaacg gagtttgccg cccaccagca
     5401 tagcagagta aatgaagcat tgctgtctgt tctccagacc atttgtcata agaaatggta
     5461 gatctggcac tgtccttcac agcttactta aagaacatga ctgaagcact tcctgcgctg
     5521 gggtacaaag ctgttggcct gggctctctc cttataaaca tggtggattc tgaatcactc
     5581 ctctgtatta ggtgtatatt ctcactctaa agtattgtgg ttaatgaaaa ataaatcttg
     5641 tacagatgtc attaaacttg ctttttaagt ttt
//
