LOCUS       NM_080695               2393 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus calcium voltage-gated channel auxiliary subunit
            gamma 7 (Cacng7), mRNA.
ACCESSION   NM_080695 XM_006228013
VERSION     NM_080695.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2393)
  AUTHORS   Larsson,M., Agalave,N., Watanabe,M. and Svensson,C.I.
  TITLE     Distribution of transmembrane AMPA receptor regulatory protein
            (TARP) isoforms in the rat spinal cord
  JOURNAL   Neuroscience 248, 180-193 (2013)
   PUBMED   23751177
REFERENCE   2  (bases 1 to 2393)
  AUTHORS   Studniarczyk,D., Coombs,I., Cull-Candy,S.G. and Farrant,M.
  TITLE     TARP gamma-7 selectively enhances synaptic expression of
            calcium-permeable AMPARs
  JOURNAL   Nat Neurosci 16 (9), 1266-1274 (2013)
   PUBMED   23872597
REFERENCE   3  (bases 1 to 2393)
  AUTHORS   Waithe,D., Ferron,L. and Dolphin,A.C.
  TITLE     Stargazin-related protein gamma is associated with signalling
            endosomes in superior cervical ganglion neurons and modulates
            neurite outgrowth
  JOURNAL   J Cell Sci 124 (Pt 12), 2049-2057 (2011)
   PUBMED   21610096
REFERENCE   4  (bases 1 to 2393)
  AUTHORS   Yang,L., Katchman,A., Morrow,J.P., Doshi,D. and Marx,S.O.
  TITLE     Cardiac L-type calcium channel (Cav1.2) associates with gamma
            subunits
  JOURNAL   FASEB J 25 (3), 928-936 (2011)
   PUBMED   21127204
REFERENCE   5  (bases 1 to 2393)
  AUTHORS   Kato,A.S., Gill,M.B., Ho,M.T., Yu,H., Tu,Y., Siuda,E.R., Wang,H.,
            Qian,Y.W., Nisenbaum,E.S., Tomita,S. and Bredt,D.S.
  TITLE     Hippocampal AMPA receptor gating controlled by both TARP and
            cornichon proteins
  JOURNAL   Neuron 68 (6), 1082-1096 (2010)
   PUBMED   21172611
REFERENCE   6  (bases 1 to 2393)
  AUTHORS   Soto,D., Coombs,I.D., Renzi,M., Zonouzi,M., Farrant,M. and
            Cull-Candy,S.G.
  TITLE     Selective regulation of long-form calcium-permeable AMPA receptors
            by an atypical TARP, gamma-5
  JOURNAL   Nat Neurosci 12 (3), 277-285 (2009)
   PUBMED   19234459
  REMARK    Erratum:[Nat Neurosci. 2009 Jun;12(6):808]
REFERENCE   7  (bases 1 to 2393)
  AUTHORS   Ferron,L., Davies,A., Page,K.M., Cox,D.J., Leroy,J., Waithe,D.,
            Butcher,A.J., Sellaturay,P., Bolsover,S., Pratt,W.S., Moss,F.J. and
            Dolphin,A.C.
  TITLE     The stargazin-related protein gamma 7 interacts with the
            mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and
            regulates the stability of specific mRNAs, including CaV2.2
  JOURNAL   J Neurosci 28 (42), 10604-10617 (2008)
   PUBMED   18923037
REFERENCE   8  (bases 1 to 2393)
  AUTHORS   Kato,A.S., Siuda,E.R., Nisenbaum,E.S. and Bredt,D.S.
  TITLE     AMPA receptor subunit-specific regulation by a distinct family of
            type II TARPs
  JOURNAL   Neuron 59 (6), 986-996 (2008)
   PUBMED   18817736
REFERENCE   9  (bases 1 to 2393)
  AUTHORS   Kato,A.S., Zhou,W., Milstein,A.D., Knierman,M.D., Siuda,E.R.,
            Dotzlaf,J.E., Yu,H., Hale,J.E., Nisenbaum,E.S., Nicoll,R.A. and
            Bredt,D.S.
  TITLE     New transmembrane AMPA receptor regulatory protein isoform,
            gamma-7, differentially regulates AMPA receptors
  JOURNAL   J Neurosci 27 (18), 4969-4977 (2007)
   PUBMED   17475805
REFERENCE   10 (bases 1 to 2393)
  AUTHORS   Chu,P.J., Robertson,H.M. and Best,P.M.
  TITLE     Calcium channel gamma subunits provide insights into the evolution
            of this gene family
  JOURNAL   Gene 280 (1-2), 37-48 (2001)
   PUBMED   11738816
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Oct 11, 2022 this sequence version replaced
            XM_006228013.4, NM_080695.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.1185.1,
                                           SRR26360194.682765.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840106 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               JAXUCZ010000001.1  74746430-74746669   c
            241-465             JAXUCZ010000001.1  74742836-74743060   c
            466-552             JAXUCZ010000001.1  74741219-74741305   c
            553-693             JAXUCZ010000001.1  74740734-74740874   c
            694-839             JAXUCZ010000001.1  74717707-74717852   c
            840-2393            JAXUCZ010000001.1  74715483-74717036   c
FEATURES             Location/Qualifiers
     source          1..2393
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..2393
                     /gene="Cacng7"
                     /note="calcium voltage-gated channel auxiliary subunit
                     gamma 7"
                     /db_xref="GeneID:140728"
                     /db_xref="RGD:628807"
     exon            1..240
                     /gene="Cacng7"
                     /inference="alignment:Splign:2.1.0"
     exon            241..465
                     /gene="Cacng7"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..1097
                     /gene="Cacng7"
                     /note="neuronal voltage-gated calcium channel gamma-7
                     subunit; TARP gamma-7; transmembrane AMPAR regulatory
                     protein gamma-7; calcium channel, voltage-dependent, gamma
                     subunit 7"
                     /codon_start=1
                     /product="voltage-dependent calcium channel gamma-7
                     subunit"
                     /protein_id="NP_542426.1"
                     /db_xref="GeneID:140728"
                     /db_xref="RGD:628807"
                     /translation="MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQ
                     NQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATP
                     FPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEV
                     MNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYR
                     PRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC"
     exon            466..552
                     /gene="Cacng7"
                     /inference="alignment:Splign:2.1.0"
     exon            553..693
                     /gene="Cacng7"
                     /inference="alignment:Splign:2.1.0"
     exon            694..839
                     /gene="Cacng7"
                     /inference="alignment:Splign:2.1.0"
     exon            840..2393
                     /gene="Cacng7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attagccaat gagcggccgc cggtccctgc tccgggctgc gtccgctgag tgaggccgcg
       61 ggcgcggggg gtggggggtg ggaggccggg agggggccgg gacgccgggc tcgggggcgg
      121 gggcgggggg cgcgggcacc ggagaccccg gtggcggcag cggcggccgg ggaaaaccgc
      181 ggggccggtc atgcggctgc ggggcccgcg gcccagagcg tccgcccagc cctgagagag
      241 gccccacagg gcgccccccg ccgctcagga tgagtcactg cagcagccgc gccctgaccc
      301 tgctgagcag cgtgtttggt gcctgcggcc tgctccttgt gggcatcgcg gtcagcacgg
      361 actactggct gtatatggag gaggggaccg ttttgccgca gaaccagacc accgaggtca
      421 agatggcgct gcacgctggc ctctggagag tctgcttctt tgcaggtcgg gagaaggggc
      481 gctgtgtggc ttctgagtac tttcttgaac cagagatcaa cttggtgacg gaaaacacgg
      541 agaatattct gaagacagta cgcacggcta cacccttccc tatggtcagt ctcttccttg
      601 tgttcaccgc cttcgtcatc agcaacatcg gccacatccg acctcagagg accattcttg
      661 ccttcgtttc tggcatcttt ttcattttat caggcctctc cttggtggtg ggcttggttc
      721 tatacatctc tagcatcaac gatgaggtca tgaacaggcc cagcagctct gagcaatact
      781 ttcactatcg ctacgggtgg tcgtttgcct tcgctgcttc ttcctttctt ctgaaagagg
      841 gggccggagt catgtccgtg tacttattca ccaagcgcta cgcggaggag gagatgtatc
      901 gcccgcaccc ggccttctac cgaccgcgtc tcagcgactg ctccgactac tcgggccagt
      961 ttctgcaacc cgaagcgtgg cgtcgtggcc gcagcccttc cgacatttct agcgacgtct
     1021 ccatccagat gacgcaaaat taccctccgg ccatcaagta cccggaccac ctccacatct
     1081 ccacttcacc gtgctgagac cggagtccct ctctttcctc ttcctccctc ccttttcccg
     1141 tgcctcaccc atgaagcccc aattccttaa gggactcttg gctgagggat gctgtgccat
     1201 ttccaagccc ctacccatca tcctcatttc aacggctcca ccctttttcc aaatctctcc
     1261 tcgttgatcc tttatacttc caaatgattc ctcctcacct cgccctcgtg agcctgtccc
     1321 ctttccctta ggtccctccc caccggttaa ttccaaccgc gtttactatc ttctggtggc
     1381 gtcttgcacc tagctccccc gaactccacc ggactcccgc ttccgggtag gggtgctggg
     1441 caggagagtg ggtgtggcag ccactggaat gccctggaat tcccactcca tcctctccta
     1501 gcacatcacc aggtgccctg caggtccctg gtggcagcga gtggggataa gcttgctctg
     1561 cccacaggaa tgtgactatg actgacattt cctctctttt ctcctctgga aaatgacctt
     1621 tctttcctct aatattctcc ttctcttctt tcttcctcct cctctcttct ttctttcctt
     1681 ccttcctcct tctccttcgt tctcctcctc ttcctctgcc ttttcctccc ccacctcctc
     1741 ttcccacttc gtttttcctc cttccacctg ctcatccaaa gcccctaggt gcatccagcc
     1801 tctcacacca aacaaggatg ggaccccagg gtggagggag gttccctcat gctatctcca
     1861 cacctgtgcc cgcctcttcc ccctcgaggt tccgtcgggg gagggagagg cagtagcggg
     1921 ggttaacacc ccccaaaacc tctgtcttcc attttctggt actccctctc atccatgtcc
     1981 ctcttcccat ctcagatccc caactctggc ctctttcaag ggcctgtccg cccccttgga
     2041 cagattcggg ggtgggggag gtcgccagaa aaccgcccat cccactccct ttattagggg
     2101 aggaggggcg aggtagcaca gtgttaacac acggaaccag atcggccccg gggtgggggg
     2161 aggggggcag gggagggacg ggggctttta gtttgcatct taggggggag ggagggaggg
     2221 agaaccgcag cagttataac ctgtctttac gcagcgattt ttaatgagtc tgggggaggg
     2281 gggagggaag caataagggt ggggaaccgg tggggtgggg ggcctggctc tgttatttac
     2341 cgtgtatcat atgtaaatat cgacagaaac ttcaataaac tttatttcaa aca
//
