LOCUS       NM_001007730            2954 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus calcium binding protein 7 (Cabp7), mRNA.
ACCESSION   NM_001007730 XM_341247
VERSION     NM_001007730.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2954)
  AUTHORS   Mikhaylova,M., Reddy,P.P., Munsch,T., Landgraf,P., Suman,S.K.,
            Smalla,K.H., Gundelfinger,E.D., Sharma,Y. and Kreutz,M.R.
  TITLE     Calneurons provide a calcium threshold for trans-Golgi network to
            plasma membrane trafficking
  JOURNAL   Proc Natl Acad Sci U S A 106 (22), 9093-9098 (2009)
   PUBMED   19458041
  REMARK    GeneRIF: calneuron-1 and calneuron-2 physically associate with
            PI-4Kbeta, inhibit the enzyme profoundly at resting and low calcium
            levels, and negatively interfere with Golgi-to-plasma membrane
            trafficking.
REFERENCE   2  (bases 1 to 2954)
  AUTHORS   McCue,H.V., Burgoyne,R.D. and Haynes,L.P.
  TITLE     Membrane targeting of the EF-hand containing calcium-sensing
            proteins CaBP7 and CaBP8
  JOURNAL   Biochem Biophys Res Commun 380 (4), 825-831 (2009)
   PUBMED   19338761
REFERENCE   3  (bases 1 to 2954)
  AUTHORS   Mikhaylova,M., Sharma,Y., Reissner,C., Nagel,F., Aravind,P.,
            Rajini,B., Smalla,K.H., Gundelfinger,E.D. and Kreutz,M.R.
  TITLE     Neuronal Ca2+ signaling via caldendrin and calneurons
  JOURNAL   Biochim Biophys Acta 1763 (11), 1229-1237 (2006)
   PUBMED   17055077
  REMARK    GeneRIF: The calcium sensor protein caldendrin is abundantly
            expressed in neurons and is thought to play an important role in
            different aspects of synapto-dendritic Ca2+ signaling.
            Review article
REFERENCE   4  (bases 1 to 2954)
  AUTHORS   Haeseleer,F., Imanishi,Y., Sokal,I., Filipek,S. and Palczewski,K.
  TITLE     Calcium-binding proteins: intracellular sensors from the calmodulin
            superfamily
  JOURNAL   Biochem Biophys Res Commun 290 (2), 615-623 (2002)
   PUBMED   11785943
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC081959.1 and JAXUCZ010000014.1.
            
            On Mar 12, 2015 this sequence version replaced NM_001007730.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY841152.1, BC081959.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2950              BC081959.1         69-3018
            2951-2954           JAXUCZ010000014.1  83822322-83822325   c
FEATURES             Location/Qualifiers
     source          1..2954
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..2954
                     /gene="Cabp7"
                     /gene_synonym="rCaBP7"
                     /note="calcium binding protein 7"
                     /db_xref="GeneID:360970"
                     /db_xref="RGD:1359269"
     exon            1..483
                     /gene="Cabp7"
                     /gene_synonym="rCaBP7"
                     /inference="alignment:Splign:2.1.0"
     CDS             375..1022
                     /gene="Cabp7"
                     /gene_synonym="rCaBP7"
                     /note="calneuron-2; calneuron-II"
                     /codon_start=1
                     /product="calcium-binding protein 7"
                     /protein_id="NP_001007731.1"
                     /db_xref="GeneID:360970"
                     /db_xref="RGD:1359269"
                     /translation="MPFHPVTAALMYRGIYTVPNLLSEQRPVDIPEDELEEIREAFKV
                     FDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFVTLLGPKL
                     STSGIPEKFHGTDFDTVFWKCDMQKLTVDELKRLLYDTFCEHLSMKDIENIIMTEEES
                     HLGTAEECPVDVETCSNQQIRQTCVRKSLICAFAIAFIISVMLIAANQVLRSGMK"
     exon            484..627
                     /gene="Cabp7"
                     /gene_synonym="rCaBP7"
                     /inference="alignment:Splign:2.1.0"
     exon            628..740
                     /gene="Cabp7"
                     /gene_synonym="rCaBP7"
                     /inference="alignment:Splign:2.1.0"
     exon            741..894
                     /gene="Cabp7"
                     /gene_synonym="rCaBP7"
                     /inference="alignment:Splign:2.1.0"
     exon            895..2954
                     /gene="Cabp7"
                     /gene_synonym="rCaBP7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggcggga gccggagcgg cgggccgggc agccgcacca gcaagcggac gagcgggcgg
       61 cgagcaacgc ggagcgcacg gggcagcgcg gagggagcgc aacgcgcagc ggtcggagcc
      121 gagaggccaa agcggcgccg cccccgccgt ccctgcgagg ccccggccgg gatcccgacg
      181 agggagccgg cggcatggcc ggacagcccg gggcgcgggg gcgctaggtc ccgggcgggt
      241 gcccattgcc tcgccgccgc cactgcgcgc cgcaccgcgc gccccgcccg ctccagccgc
      301 ccccggggcc gccggcggcc catgagcccc ggcctcaaag tttgcggcgg gcgggcgggc
      361 gcggagcctc caagatgccg ttccacccgg tgacggcggc gttgatgtac cggggcatct
      421 acaccgtgcc caacctgctg tcggagcagc gcccggtgga tatccctgaa gacgagctag
      481 aggagatccg agaggccttc aaggtattcg accgagatgg caatggcttc atctctaagc
      541 aggagctggg aacggccatg cgctccctgg gctacatgcc caacgaggtg gagcttgagg
      601 ttatcatcca gcggctagat atggatggtg acggccaagt cgactttgag gagtttgtaa
      661 cgctcctggg accgaagctt tccacctcag ggatcccaga gaagttccac ggcacggact
      721 ttgacaccgt cttctggaag tgtgacatgc agaagctgac ggtggacgag ctgaaacgac
      781 ttctctatga caccttctgt gagcacctgt ccatgaagga catagagaac atcatcatga
      841 cggaggagga gagccacctg ggcacggctg aggagtgtcc cgtggacgtg gagacctgtt
      901 ccaaccagca gatccgccag acgtgcgtgc gcaagagcct catctgcgcc ttcgccatcg
      961 ccttcatcat cagtgtcatg ctcatcgcgg ccaaccaggt gctgcgcagt ggcatgaagt
     1021 aggcgcccgc ggtgcccacc tggcccgctc cacacccacc gctgcctgca gccctcccct
     1081 agcttgctcc ctgggccacc gcccctgggc atttcgagcc tggacattga ccaccccaaa
     1141 cctcaccccg taggccttgc atggagccat agcccagctg tggaggaccg ggtggtggct
     1201 ttgaggacag ccctagccct aaaccctgcc tgtgccctca cctggcctgt atgtagcgct
     1261 cacttcccac cactaaggag ctcctggaaa aggagcccca ggatccagtt agtgctgtga
     1321 tcttttagcc aggcaaggaa ctcatgtcca gagtagtggg cagggtggag gtgggcacag
     1381 ggctgaggct actgggtctc cttctctgac actccttaga cccaaagcca gtcctccacg
     1441 taccttctgg ggcctgtgtc tgcccatttc acaggtgagg aacctgaggc tttaaggctt
     1501 tgagatttgg cttcagactc ttcttccacg gggcttttca ggaaaggcag atgcccatgc
     1561 aagatggggc atgagagata gcccctaggc ccatgaattt ctgagccatc caccagaggc
     1621 ctagagacca agggccacat tgtcacctag cacagaacct agaaacccaa ctgaggaagg
     1681 aagtgcagat cctgcagccc ttgtgactcc ccactggcca gggtgcaacc ttggaaggcc
     1741 ctgagccact ccctagggag ccactcccct gagggtctgc cacagccctg tcagtggcta
     1801 cagaccactc ttccaagtcc agggcctgcc ctcttgggaa ccctacttct ctgttccctc
     1861 caggccagag atctggctct catgctcccc cacccccctc atgccattcc ttggcaccag
     1921 ctcagcctgg gcagatgcaa gccttcagct cttcaggggc cgggacgatt ggcagtcctc
     1981 ggctcccttc cccagcctgg ggccacttac tagctgggct gccgccacac tggcatacgc
     2041 tgtgcccagc ctggctgagc ctctgctgat tccctaagca cccaggaggg gatattgtct
     2101 cattccagcc cacctgtctc ctgagggagg caggaaagag tcaagaacag gagtgccagc
     2161 aagacagaca ggccagccac tgaggaaaga ctttctttat aaacactgga atgttcttcc
     2221 tgagaaatgg cctgagggat ggtgagtgga tggggaggcc aggctcagag gccccagggc
     2281 aaacagaggg aaggcggctc tgcttcctag gttgagtctt tgctatgact gatgaggcag
     2341 gtgggaagtc aggcagggag gtggggaaga gctcagcccc actggactct ggactgtacg
     2401 gaccatccac caggtggggg tgccctcagg gaggggggca gctcctgcat tggtggccag
     2461 cccactgggt actgaaagac agtggttctg atgggttcag ccctggagag gagaaaggta
     2521 gaggattaga acggggcacc tcacagaccc acttcgctct tctaccatac tggctgtcag
     2581 gaagggtagc cacctgcatg gcccttctgg aagtagaacc ttgataacat gcagaccctc
     2641 tgagccagcc acctcttctc ggaactgagc ccaaggtggg ggctagcccc agagactggc
     2701 cttgggcaat atggaagtac tcttagtgtc cgttcacctg tgggggactg ggtaaatatt
     2761 tatgcacgtc cacagcagag aatgctatgc agcctgtgta aaaatcaagg cctatatgca
     2821 ctgatgaaga aagatatact atgtgagtat ggagaaaaag cagcttataa aataatgtat
     2881 atagcatgat actatttttg tttaaagata tatgacatat ataaatgcat aaaaacaacc
     2941 ctggaagtta cagc
//
