LOCUS       NM_001024265            1394 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus similar to human chromosome 11 open reading frame
            65 (C8h11orf65), mRNA.
ACCESSION   NM_001024265 XM_236274
VERSION     NM_001024265.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Lee,J., Pappalardo,Z., Chopra,D.G., Hennings,T.G., Vaughn,I.,
            Lan,C., Choe,J.J., Ang,K., Chen,S., Arkin,M., McManus,M.T.,
            German,M.S. and Ku,G.M.
  TITLE     A Genetic Interaction Map of Insulin Production Identifies Mfi as
            an Inhibitor of Mitochondrial Fission
  JOURNAL   Endocrinology 159 (9), 3321-3330 (2018)
   PUBMED   30059978
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC092578.1.
            
            On May 27, 2005 this sequence version replaced XM_236274.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092578.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1394
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /note="similar to human chromosome 11 open reading frame
                     65"
                     /db_xref="GeneID:315665"
                     /db_xref="RGD:1311251"
     exon            1..141
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            142..191
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            192..281
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     CDS             201..1118
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /note="uncharacterized protein C11orf65 homolog;
                     mitochondrial fission factor interactor"
                     /codon_start=1
                     /product="protein MFI"
                     /protein_id="NP_001019436.1"
                     /db_xref="GeneID:315665"
                     /db_xref="RGD:1311251"
                     /translation="MSMKRPQDHSKQEMAARIIQKAWKTFLNVSVFQHFKSLIDLRRQ
                     GEPRQIVKYINPKEAELLDAAAGVQVRFRLGGVKFPPEIYYKIFTHRHIEDLCANSPR
                     DYTKLPARYASHNKDDPPQVEDNSGWYRRIENNGWRPVSNRFWMPTENEVLESTKESE
                     FHFSKLKRKQDLEKKRKIKKIEWMRQMYYLGSLEAKVTDRETLVLIHKATKGLIKSIE
                     DGGVDSVMEWEVDEVLNWTNTLNFDDYIASWRETATSNSSAYLKDAKLQRIQKSLQRK
                     IYEDETKESEEKIYYDGDFYENVYIKPLL"
     exon            282..374
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            375..428
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            429..629
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            630..760
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            761..931
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            932..987
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1375
                     /gene="C8h11orf65"
                     /gene_synonym="Mfi; RGD1311251"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctgaacca gtttggagtg gcacggtgcc tcacaaaagg agtaatataa ataaacattc
       61 tgtttttact ggcactgtgg aatttctgct actaatggga gctcatggat ttggacctct
      121 gcactgagtc cagcgagcca gtggaagaac atggcggttc atgccttcta agaaaatgtc
      181 ctacaattga gaacttccaa atgtctatga aacgtcccca agatcattca aagcaggaaa
      241 tggctgcaag gatcattcag aaggcctgga aaactttcct taatgtttcc gtgttccagc
      301 attttaaaag tctgattgac ttacgaagac aaggggagcc tcgccagata gtgaagtaca
      361 ttaaccctaa agaggcagag ctcctagatg ctgctgctgg cgtccaagtc cgattcagac
      421 tgggcggggt taaatttcca cctgagatat actataaaat ttttactcac agacatatcg
      481 aagatctgtg tgctaacagc cctcgagatt acacaaagct tccggcaaga tacgcatctc
      541 ataacaaaga cgatccacct caggtggagg acaacagtgg ctggtatcgc cgcatagaga
      601 acaatggctg gaggcctgtc tccaatagat tttggatgcc aactgaaaac gaagtgttgg
      661 agagcacaaa ggaaagcgaa tttcatttct ccaaactgaa gagaaagcaa gatctggaaa
      721 agaaaagaaa aattaaaaaa attgagtgga tgaggcaaat gtactacctg ggcagcctgg
      781 aggccaaggt aacagaccgt gagacactag ttctaatcca caaagcaaca aaaggcctaa
      841 tcaagagtat cgaagatggc ggagtggact ctgtgatgga atgggaagtc gatgaggtgc
      901 tgaactggac aaacacgctc aacttcgatg attatatcgc aagttggaga gaaactgcta
      961 caagcaactc ttcagcttac ctaaaagatg ccaagcttca acgaatacag aagagcctac
     1021 agagaaagat ctatgaggat gaaacaaagg agtcagagga gaaaatatat tatgatggtg
     1081 atttctatga aaatgtttat ataaaaccac tactttaaca cctggttcca tgtttggcag
     1141 ataaagaacc ataaagaatt tccttttctc agcaatggcc catcaagccc acttcccagt
     1201 gaaagccaag agctacttat tgtgattaca acgtattgtg tacgtattac ttatagttaa
     1261 ggaatactga agaaatacta ccctggacaa tgtatagttc ctcctggcat tctgagaaac
     1321 tgtagttgtt tgacagttat acttaaaata aagatacttt tttggggatt aaaaaaaaaa
     1381 aaaaaaaaaa aaaa
//
