LOCUS       NM_001399303             793 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus complement C8 gamma chain (C8g), transcript
            variant 1, mRNA.
ACCESSION   NM_001399303 XM_006233581
VERSION     NM_001399303.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 793)
  AUTHORS   Bastos-Amador,P., Royo,F., Gonzalez,E., Conde-Vancells,J.,
            Palomo-Diez,L., Borras,F.E. and Falcon-Perez,J.M.
  TITLE     Proteomic analysis of microvesicles from plasma of healthy donors
            reveals high individual variability
  JOURNAL   J Proteomics 75 (12), 3574-3584 (2012)
   PUBMED   22516433
REFERENCE   2  (bases 1 to 793)
  AUTHORS   Ng,S.C. and Sodetz,J.M.
  TITLE     Biosynthesis of C8 by hepatocytes. Differential expression and
            intracellular association of the alpha-gamma- and beta-subunits
  JOURNAL   J Immunol 139 (9), 3021-3027 (1987)
   PUBMED   3312411
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 6, 2022 this sequence version replaced XM_006233581.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214907.1, BU759612.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               JAXUCZ010000003.1  28720063-28720232   c
            171-307             JAXUCZ010000003.1  28719808-28719944   c
            308-378             JAXUCZ010000003.1  28719558-28719628   c
            379-486             JAXUCZ010000003.1  28719367-28719474   c
            487-588             JAXUCZ010000003.1  28719007-28719108   c
            589-627             JAXUCZ010000003.1  28718899-28718937   c
            628-793             JAXUCZ010000003.1  28718648-28718813   c
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..793
                     /gene="C8g"
                     /note="complement C8 gamma chain"
                     /db_xref="GeneID:296545"
                     /db_xref="RGD:1309074"
     exon            1..170
                     /gene="C8g"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..641
                     /gene="C8g"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; complement component 8, gamma subunit;
                     complement component C8 gamma chain; complement component
                     8, gamma polypeptide"
                     /codon_start=1
                     /product="complement component C8 gamma chain isoform 1
                     precursor"
                     /protein_id="NP_001386232.1"
                     /db_xref="GeneID:296545"
                     /db_xref="RGD:1309074"
                     /translation="MLSPGAVLFFTLILMASSLGQRTRKPYGSTSPISTIQAQANFNA
                     QQFAGTWLLVAVGSACRFLQEQGHRAEATTLHIAPQGAAMAASTFRKLDGICWQVRQL
                     YGITGVPGRFLLQAPRARGPVHVVVAETDYQSFAILYLEQARRLSVKLYTRTLPVSDS
                     ALNAFEERVRGANLTEDQIFFFPKYGFCETADQFHILNEMPK"
     exon            171..307
                     /gene="C8g"
                     /inference="alignment:Splign:2.1.0"
     exon            308..378
                     /gene="C8g"
                     /inference="alignment:Splign:2.1.0"
     exon            379..486
                     /gene="C8g"
                     /inference="alignment:Splign:2.1.0"
     exon            487..588
                     /gene="C8g"
                     /inference="alignment:Splign:2.1.0"
     exon            589..627
                     /gene="C8g"
                     /inference="alignment:Splign:2.1.0"
     exon            628..793
                     /gene="C8g"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgtcctat cacctactgt cacagaacgg ccatgctgtc ccccggggct gttttattct
       61 tcaccctgat cttgatggcc agttcgctgg gccaaaggac tcgaaaacct tatgggtcta
      121 catcccccat cagcaccatc caggcccagg ccaatttcaa tgctcagcag tttgcaggga
      181 catggctcct tgtggctgtg ggctctgcat gccgctttct tcaggagcag ggacaccggg
      241 ctgaggccac tacattgcac atagctcccc agggtgcagc tatggctgcc agcaccttcc
      301 gaaagctaga cgggatctgc tggcaggtgc gccaactcta tggaatcaca ggggtccctg
      361 gccgcttctt gctccaagct ccacgggccc gtgggccagt acatgtggtt gttgctgaga
      421 ccgactacca gagctttgcc atcctgtatc tggagcaggc gaggaggctg tctgtgaaac
      481 tatacacccg cacactgcct gtgagtgatt ctgccctgaa tgcgtttgag gagcgagtca
      541 ggggagccaa cctgacagaa gaccagatct ttttctttcc caagtatggt ttctgtgaga
      601 ctgcagacca attccacatc ctgaatgaga tgccgaagtg aaatgaggcc atctagtaga
      661 gaagctatgg actcccctca gagagttctg agcatcctga atacaatctt ggagtctttc
      721 ctgtctctcc ccagaagcac cccttcatac ggctctgttg tcctgagact tttcagtaaa
      781 catcagactt ggc
//
