LOCUS       NM_001191602            7152 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus C2 domain containing 3 centriole elongation
            regulator (C2cd3), mRNA.
ACCESSION   NM_001191602 XM_215006
VERSION     NM_001191602.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7152)
  AUTHORS   Thauvin-Robinet,C., Lee,J.S., Lopez,E., Herranz-Perez,V., Shida,T.,
            Franco,B., Jego,L., Ye,F., Pasquier,L., Loget,P., Gigot,N.,
            Aral,B., Lopes,C.A., St-Onge,J., Bruel,A.L., Thevenon,J.,
            Gonzalez-Granero,S., Alby,C., Munnich,A., Vekemans,M., Huet,F.,
            Fry,A.M., Saunier,S., Riviere,J.B., Attie-Bitach,T.,
            Garcia-Verdugo,J.M., Faivre,L., Megarbane,A. and Nachury,M.V.
  TITLE     The oral-facial-digital syndrome gene C2CD3 encodes a positive
            regulator of centriole elongation
  JOURNAL   Nat Genet 46 (8), 905-911 (2014)
   PUBMED   24997988
REFERENCE   2  (bases 1 to 7152)
  AUTHORS   Ye,X., Zeng,H., Ning,G., Reiter,J.F. and Liu,A.
  TITLE     C2cd3 is critical for centriolar distal appendage assembly and
            ciliary vesicle docking in mammals
  JOURNAL   Proc Natl Acad Sci U S A 111 (6), 2164-2169 (2014)
   PUBMED   24469809
REFERENCE   3  (bases 1 to 7152)
  AUTHORS   Balestra,F.R., Strnad,P., Fluckiger,I. and Gonczy,P.
  TITLE     Discovering regulators of centriole biogenesis through siRNA-based
            functional genomics in human cells
  JOURNAL   Dev Cell 25 (6), 555-571 (2013)
   PUBMED   23769972
  REMARK    Erratum:[Dev Cell. 2013 Jul 29;26(2):220]
REFERENCE   4  (bases 1 to 7152)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   5  (bases 1 to 7152)
  AUTHORS   Hoover,A.N., Wynkoop,A., Zeng,H., Jia,J., Niswander,L.A. and Liu,A.
  TITLE     C2cd3 is required for cilia formation and Hedgehog signaling in
            mouse
  JOURNAL   Development 135 (24), 4049-4058 (2008)
   PUBMED   19004860
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000001.1.
            
            On Jul 17, 2010 this sequence version replaced XM_215006.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.2294.1,
                                           SRR26643429.2769.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                JAXUCZ010000001.1  164127694-164127748
            56-325              JAXUCZ010000001.1  164129565-164129834
            326-483             JAXUCZ010000001.1  164133723-164133880
            484-707             JAXUCZ010000001.1  164144497-164144720
            708-955             JAXUCZ010000001.1  164145399-164145646
            956-1088            JAXUCZ010000001.1  164149530-164149662
            1089-1178           JAXUCZ010000001.1  164150109-164150198
            1179-1326           JAXUCZ010000001.1  164153796-164153943
            1327-1478           JAXUCZ010000001.1  164158884-164159035
            1479-1646           JAXUCZ010000001.1  164159773-164159940
            1647-1759           JAXUCZ010000001.1  164160557-164160669
            1760-1878           JAXUCZ010000001.1  164162979-164163097
            1879-2001           JAXUCZ010000001.1  164165493-164165615
            2002-2520           JAXUCZ010000001.1  164168179-164168697
            2521-2672           JAXUCZ010000001.1  164170548-164170699
            2673-2919           JAXUCZ010000001.1  164172153-164172399
            2920-3100           JAXUCZ010000001.1  164174821-164175001
            3101-3284           JAXUCZ010000001.1  164177327-164177510
            3285-3457           JAXUCZ010000001.1  164178543-164178715
            3458-3581           JAXUCZ010000001.1  164180091-164180214
            3582-3850           JAXUCZ010000001.1  164182909-164183177
            3851-3940           JAXUCZ010000001.1  164183597-164183686
            3941-4540           JAXUCZ010000001.1  164184579-164185178
            4541-4879           JAXUCZ010000001.1  164188400-164188738
            4880-5018           JAXUCZ010000001.1  164192227-164192365
            5019-5083           JAXUCZ010000001.1  164194031-164194095
            5084-5289           JAXUCZ010000001.1  164197415-164197620
            5290-5420           JAXUCZ010000001.1  164198183-164198313
            5421-5582           JAXUCZ010000001.1  164202840-164203001
            5583-5803           JAXUCZ010000001.1  164205782-164206002
            5804-6698           JAXUCZ010000001.1  164208910-164209804
            6699-6810           JAXUCZ010000001.1  164214185-164214296
            6811-7152           JAXUCZ010000001.1  164224312-164224653
FEATURES             Location/Qualifiers
     source          1..7152
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..7152
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /note="C2 domain containing 3 centriole elongation
                     regulator"
                     /db_xref="GeneID:293148"
                     /db_xref="RGD:1307366"
     CDS             1..6960
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /note="C2 calcium-dependent domain containing 3"
                     /codon_start=1
                     /product="C2 domain-containing protein 3"
                     /protein_id="NP_001178531.1"
                     /db_xref="GeneID:293148"
                     /db_xref="RGD:1307366"
                     /translation="MKQRKGQVPGGGRGRKKRGLSDISPSTSLPPLVEGQLRCFLKLT
                     INKVVWKIAKPPASVLVRVRWWGETSDGTLFCPRDALQTEPKAVRTTTRYAIRCGPKQ
                     FTSYLTDMAVLVLEVITKFDHLPVGRVQISGLAQLSPTHQINGFFTIVSPASKKLGEL
                     QVSLALEPLSETYDSYKPLPATEVTENVLLSERELRENAESSNNQSRIPSGSYRVPAI
                     KTDGKELAGNSSRSTTPRGKDHLYFAENSDAVKSSSCGPRHQLNQGTNVETVTLRGKA
                     PQKQLSLLNRSEFQPQINTVAKSHSDSCILSSNNPPTKDLLSALLEQGSRLRNAMLIS
                     AMNTSPDTSMLLDKVPPPVADDVSRSPVLNSPTNQCKGHREDHLLPLVDTRAIQLLLG
                     SAELSQSHCWNGLGSPPDSPAPGSDVYCSSDLNDPQYDQSLLENLFYTVPKSDVGASD
                     FLSEDDGLEPSKTMNQSKASDRSKVEGSREQKLKKRAAVKKSRNAAMSLSVDRLALLG
                     RVHAVRIIIEAMGVPPDSPHATPSRKIFAGKPPKPAAAKKCTFFVEYHFPVGFSKNGL
                     GKTALITEVVRLASSKISDGVVKFQQRFVCPIEFGGAMIEHWWSSNLTFQVYAKKTPQ
                     KKPEAVGSASLPLRAVLESELLAFSRQLPVQQENGLSSLGPLKVTMELVLGNKDFTGI
                     SAKLRRSTQPAPPSAAASLDAVLPETGQGTACTNSTTCTTCTNSPQSPNKIHKETTKK
                     TQNLVFPEPESASSVASNSSAFMVMPPSNLVPQVNGSAKEDGLLLHVLLMVPDGKDFV
                     FGEPEKQPSCNVYLNCKLFSTEEVTRSVVSWGTTQPVFNFSQVIPVSLSSKCLERLKN
                     NVMIIETWNKARSPGQDQLLGLVKLPLHQFYMSFKDPKISRLLLDARYPVVAVDSYMP
                     VIDVFSGHQNGSLRVFLAMGSSDQIMMLQRLKNEEGTLPPFSPRPAHFLDQPPVASVA
                     MPEKQGAQLVEHHFEFHVVMVKGLMPLQATVWGEADCYVQYYFPFQDSQPSMLQGPAL
                     LENGITLKPFRTSTTLCVPDPVFNSQHHHSLLLPTEVPVQRLLLSAFSSQGLVPGGGV
                     QFEIWCRYYYPNVRDQMVAKGTLPLSRISAMVTMQHREDIGTQNFNLPLTPRLEPSKE
                     LKSQSSGFLDVSLRYRRSPRTAEGVLAARAVSISVQIIRACGLQAAAKALAEQEPALQ
                     FSAAVGVNASVTTHLSFLPKGEQRQTRPVACSFCPEFSHHLEFPCNLVTQHCSGEACF
                     LAELLEFAEIIFAIYHENTKSVSDITRIQSCKNYLLGVVKVPTKDLLVKRSGITGWYP
                     VILPEDEGLHQGLEFMQKIVGGLELSVSFTHPGDRERVLEAAELLGWSFEDTPKDLVK
                     MEEEVPATVTISTPRLWLPLHCVLLAGHKNIHKNTYCYLRYKLYNQEAFWTPLRKPKE
                     STDNQVLVTFKASKRAEVTRSQSLLWYFREEKLEIQVWRAYGNDNLERPHQTDSWIGS
                     AYVDLSRLGEKSTRTLTVSGVYPLFGRNASDLSGAALRVHVVLSPFFPHSEPSRELDS
                     MDCSSHSESEQLPRKSDEPQLSPPCVLQKSPASTQVHGNSTAADVCPSQQGPPELDGT
                     FAVSILVERAMHLSLKGSPLTDRKVSVPSCCVSFATATEPSPVYTHVVENTDSPIWGF
                     QQQSRLSKELLLDPHQTLVFKVWHKGDEERVVGFASVDLSPLLSGFQFICGWYNITDF
                     SGECQGQIKVAISPMESLMHFKEERQARRGIETPGSLIPMFSPLSFPASTVCDAFPGP
                     MARHIPGLPAHAAPEEDLSSPARNGTIRNQAARHEEHVQNIRRFHESLQHGEAVLPSD
                     GKPTTVPSTPHTSILTCLRKNLSELDEIQKYFNQKLSKPLLPFSSQSSPAVSQSQESQ
                     REPVSVRTSSRDPESQCILEKSSNLVLQVSSLISDLQTITRDSQAALTSHQARSRSRA
                     VATLPVARDTEAVREGSTTPEEPLAGAIEASPESLPPPAEAPSEGGGMVRESLEQTVP
                     IMRVQSSDDTEVGPDYSDEDYEEDIIEPRTLNEITTVTDKTSPWSSFMSDMSEILSPQ
                     PNEVQREGPSPEPFPREELKVRSSPQKALSPHSAQGSPSQSVFCEGGAYEIKVEDLAS
                     TKPQLVPSLTFSEPQESTDCVEQYPPQVNQGKKPTPEILAESEAFSSEFSDSSESFEK
                     FPLHLPSQSKREDHKKPPMDSPAVRQKQVTTGSEVSTRQKLLLPEPVVVPNFFLPPQQ
                     LEASLRMISHSPALPPPATADQDKSEATTGALAQRPCRPRPYSLPPNLPEEETRRIAR
                     IFSSQYSQKTDEA"
     exon            1..55
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            56..325
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            326..483
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            484..707
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            708..955
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1088
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1178
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1326
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1478
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1646
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1759
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            1760..1878
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2001
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            2002..2520
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            2521..2672
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            2673..2919
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            2920..3100
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            3101..3284
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            3285..3457
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            3458..3581
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            3582..3850
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            3851..3940
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            3941..4540
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            4541..4879
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            4880..5018
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            5019..5083
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            5084..5289
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            5290..5420
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            5421..5582
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            5583..5803
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            5804..6698
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            6699..6810
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
     exon            6811..7152
                     /gene="C2cd3"
                     /gene_synonym="RGD1307366"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaaacaac ggaaaggcca agtgcctggg ggcggccgtg ggcgcaagaa gcgaggtttg
       61 agtgacattt ccccatctac aagcctgcca cctctggttg aaggacagtt acgatgcttt
      121 ctcaaactta ctattaacaa ggtcgtatgg aagattgcga agcctcctgc ttctgtactt
      181 gtccgagtga gatggtgggg agaaacatcg gacggaaccc tcttttgtcc cagggacgca
      241 ttacagactg agccaaaagc tgtgagaaca actacccgtt atgctattcg ctgtggcccg
      301 aagcagttca cctcatacct aacagatatg gccgtgctgg tgttggaagt aatcaccaag
      361 tttgatcatc ttccagtcgg cagagttcag atcagtggac tcgcccagct ctctccaacc
      421 catcaaatca atgggttttt taccattgtt tcaccagcgt ctaagaaact tggagaactt
      481 caggtctcac ttgccctgga gcctctgtca gaaacttacg acagctacaa acctcttcct
      541 gccactgaag tgacagaaaa tgtgctttta tctgagcgag aactcagaga gaatgctgaa
      601 tccagcaaca accagtcaag gattccatca gggtcttata gggtacctgc catcaaaact
      661 gatgggaaag aattagcagg caacagcagt aggtcaacca caccaagggg aaaggaccac
      721 ttgtactttg cagagaactc cgatgcagta aagagctctt cgtgtggacc acggcatcaa
      781 cttaatcaag ggacgaatgt agagactgta accctgagag gcaaagcccc acagaagcag
      841 ctgtccctcc tgaacaggtc tgagtttcag ccacaaatta atacagtcgc caagagtcac
      901 agtgactcat gcatcctgtc ttcaaacaac ccccctacaa aggaccttct ttcagctctg
      961 ctagaacaag gcagtaggct gcggaatgcc atgttgattt ctgcaatgaa caccagccca
     1021 gatactagta tgctgctgga caaagttcct cctcctgtgg cagatgatgt ttccagatca
     1081 ccggtgctga actcacctac gaatcaatgt aaaggccacc gtgaagacca cctcctgccc
     1141 ttggtggaca ccagagctat acagctactg ttgggcagtg ctgaattatc ccagagtcat
     1201 tgctggaatg gattaggctc tcctccagat tccccggctc ctgggagtga tgtgtattgc
     1261 agcagtgacc tgaatgatcc tcagtatgac cagagtctcc tggagaactt gttttacaca
     1321 gtgcctaaat ctgatgttgg cgccagtgat ttcctcagtg aagatgatgg actggagcct
     1381 tctaaaacaa tgaaccagtc aaaagcctct gacagatcta aggttgaagg gtcacgtgag
     1441 cagaagctga agaaaagggc agctgtcaag aaaagcagaa atgcagcgat gtcactaagt
     1501 gtggatagac tggctctcct gggaagagta catgcggtca gaatcatcat tgaagccatg
     1561 ggagtccctc cagatagtcc ccatgcgaca ccaagcagga agatctttgc tgggaagcca
     1621 ccaaagccag cagcggcaaa aaagtgcact ttctttgtgg aatatcactt tcctgtgggc
     1681 ttttccaaaa atggactggg aaagacagcc ttgatcactg aggtggttcg acttgcctcc
     1741 agtaaaatct cagatggagt ggtgaaattc cagcagcggt ttgtgtgtcc catagagttt
     1801 ggtggcgcaa tgatagagca ttggtggagt tcaaacctca ccttccaagt ttatgcaaag
     1861 aaaaccccac agaaaaagcc agaagctgtt gggtctgcat ctctcccttt gcgagctgtc
     1921 cttgagtcag agctgcttgc tttcagtcgc cagcttccgg tgcaacagga aaatggtctg
     1981 tcttcacttg gccccctaaa ggtcaccatg gaacttgtct taggaaacaa ggatttcact
     2041 ggcatcagtg ctaagttaag acgcagcacc cagcctgctc caccttcagc tgctgcaagt
     2101 ctagatgcgg tactgcctga gacaggccag ggcactgcct gtaccaacag taccacctgc
     2161 accacctgta ccaacagtcc acagagccca aataaaattc acaaggaaac gacaaagaaa
     2221 acccagaatt tagtgttccc tgagccagag tcagccagct ctgtagcctc aaactcttcg
     2281 gctttcatgg ttatgccacc tagcaattta gtacctcagg taaatggctc agccaaagaa
     2341 gacggtttgc tgttacatgt gctgttgatg gtgccagatg ggaaagattt tgtttttgga
     2401 gaaccagaga aacaaccatc gtgcaatgtt tatttgaact gcaagctctt cagcacagag
     2461 gaagtcacca gatctgtcgt ctcgtggggc acaacacagc ctgtctttaa tttttctcag
     2521 gtgattcctg tctctctgtc ctccaaatgc ctggaaagac ttaagaacaa tgtgatgata
     2581 atcgaaactt ggaacaaggc gcggagcccg ggacaggacc agctgctcgg gctggtgaag
     2641 ctccctctgc accagttcta catgtccttc aaggatccca agatttctcg cctgctgctt
     2701 gatgccaggt acccagttgt tgctgtcgac agctatatgc ctgtgattga tgtattctca
     2761 ggccaccaaa atgggagtct tcgagtcttt ttagccatgg gttcttcaga tcagataatg
     2821 atgctgcaaa gattaaagaa tgaagaagga acgctccctc ccttcagccc taggccagcc
     2881 catttcctgg accagccacc tgtagcatct gttgctatgc cagaaaaaca aggagcccag
     2941 ttggtggagc accactttga gttccatgtg gtgatggtta aagggctcat gccccttcag
     3001 gcaaccgtct ggggagaagc agattgttac gtccagtact acttcccttt tcaagactcc
     3061 caacccagta tgctgcaagg acctgccctc cttgagaacg gaattactct gaagcccttt
     3121 agaacttcaa ccacactgtg tgtcccagat cccgtcttta atagtcagca ccatcactct
     3181 ctcctgctgc caaccgaggt tccagtgcag aggctcctgc tgagcgcctt ctcctcccag
     3241 gggctggtgc ctgggggtgg agtccagttt gaaatctggt gcagatacta ttatcctaat
     3301 gtaagggacc agatggttgc caaaggaacc ttgcctttat caaggatctc tgccatggta
     3361 accatgcagc accgtgaaga cattgggacg cagaacttta atctcccgtt aacccccaga
     3421 cttgagccca gcaaggaact gaagagccag tcatcaggtt tcctggatgt gagtttgaga
     3481 taccggcgta gtccaagaac agcagaggga gtccttgctg cccgagctgt ctccatctca
     3541 gtccagatta tcagagcctg tggtcttcag gcagcagcca aggctttggc tgagcaggaa
     3601 cccgctctac agtttagtgc cgctgttgga gtcaatgctt cggtcaccac ccatctctca
     3661 tttctgccca aaggggaaca gcgccaaacc cgccctgtgg cctgctcctt ctgccccgag
     3721 ttctcccatc accttgagtt cccgtgtaac ctggtgactc agcactgtag cggagaagcc
     3781 tgcttcctgg cagagctgtt ggagtttgca gaaatcattt ttgctatcta tcatgaaaat
     3841 accaaatcag tcagtgatat aaccaggatc cagtcatgca aaaactatct gcttggagta
     3901 gtaaaggttc caacaaaaga tctgctggtc aagagatctg ggatcacagg atggtatcct
     3961 gtcattttac cggaagatga aggcctgcat cagggcctgg aatttatgca gaagattgtg
     4021 ggaggcctgg agctttctgt ctccttcacg catcccggag atagagagcg ggtgttggaa
     4081 gctgctgagc tgttgggctg gagctttgag gataccccaa aggatcttgt caaaatggaa
     4141 gaagaggtgc cagccactgt caccatctcc acccccagac tctggctccc tctccactgt
     4201 gtgctgctcg ctggtcataa gaacattcat aagaatacat attgctacct tcgctacaag
     4261 ctatacaatc aagaagcctt ttggactcct ctcaggaaac ctaaggagtc tacagacaac
     4321 caggtcctgg ttaccttcaa ggcatccaaa agagcagaag ttactcggag ccagtcactg
     4381 ctttggtact tcagggagga gaagttagag atccaagtgt ggcgagctta tggcaacgat
     4441 aacttagaga ggccgcacca gaccgacagc tggattggct cagcctatgt agacctgtcc
     4501 agacttgggg aaaaatcaac aaggacacta actgtcagtg gtgtgtatcc tctgtttgga
     4561 agaaatgctt ccgacctctc tggagctgct ctgcgtgtcc atgtggttct ttcccccttc
     4621 ttcccacact ctgagccctc tcgtgagctg gactccatgg actgcagcag ccacagtgag
     4681 tctgagcagc tccccagaaa gagcgatgag ccccagctct ctccgccctg tgtgctccag
     4741 aagtctcctg cctccaccca ggtccatggc aacagcactg cagccgatgt gtgcccctcc
     4801 cagcagggcc ctcccgagtt ggatgggact tttgctgtca gcatcctggt agagagagcc
     4861 atgcacttga gcttgaaagg gagccccttg acagatcgga aagtgtccgt acctagttgt
     4921 tgtgtgtcct ttgccacagc cactgagcca tctcctgtgt acacccatgt ggttgagaat
     4981 accgattccc ccatctgggg ttttcagcag cagtccaggt tatcaaaaga gctgcttttg
     5041 gacccacatc aaaccctggt cttcaaagtg tggcataaag gagatgaaga gagggtggtt
     5101 ggctttgcct cggtggacct ctccccacta ctgtctggct ttcagtttat ctgtggctgg
     5161 tacaatatta cagacttcag tggagagtgc caagggcaaa taaaagttgc catttcccct
     5221 atggagagtc tgatgcactt taaagaagaa agacaagcaa gacgtgggat agagactcca
     5281 ggatcactga tcccaatgtt cagccccctt tccttccctg cctctactgt atgtgatgcg
     5341 ttccctgggc ccatggcaag gcacatccca ggcctgcctg ctcacgccgc tccagaggag
     5401 gatctctcct ctcctgcaag aaatggcacc ataagaaacc aggcagctcg ccatgaagag
     5461 cacgtgcaga acatccgccg ctttcacgag tccctacagc acggggaggc agtcttgcca
     5521 agtgatggga aaccaaccac agtgccttcc accccccaca cctccatcct gacgtgtctc
     5581 aggaagaatc tgagtgagct ggatgagatc cagaagtact ttaaccagaa gctcagcaag
     5641 cctttgctgc ccttcagctc tcagagctct cctgctgtct cacagagcca ggagagccag
     5701 agggaacctg tgagcgtaag aaccagcagc cgagaccccg agagccagtg catcctggag
     5761 aaatccagta acctggtgtt gcaagtcagt tccttgatct cagatctgca gactatcacc
     5821 agagattcac aagcagcttt gacttctcac caagccagga gtagaagcag agcagtcgcc
     5881 accctcccag ttgctcggga caccgaggct gttcgagaag gaagcaccac tccggaggag
     5941 ccattggcag gagctataga ggcgagccca gagtctctgc ctccccctgc tgaagcaccc
     6001 tcagagggag gagggatggt tcgtgagtca ctggaacaga cagtccccat catgagggtg
     6061 cagagcagcg atgacacgga ggtgggccca gactacagtg atgaagacta tgaggaagac
     6121 atcattgagc ccaggaccct aaatgaaata accacagtga cagacaaaac gagcccctgg
     6181 tccagtttca tgtcagacat gagtgagatc cttagccctc agcccaatga ggtacaaagg
     6241 gaaggcccct ccccagaacc tttccccaga gaggagctga aggtcagaag tagccctcaa
     6301 aaggcactca gcccccattc tgcacagggc tcccctagcc aaagtgtttt ttgtgagggt
     6361 ggagcctatg agatcaaggt tgaagacctt gcctcaacca agcctcagct tgtcccaagc
     6421 ctaacattct cagaacccca agagagcact gattgtgttg agcagtatcc accacaggta
     6481 aatcaaggta agaagcccac accagagatt ctggctgaga gtgaggcttt ctccagtgag
     6541 ttcagtgact cttctgagag ctttgagaag tttcctctgc acctaccctc ccaaagcaaa
     6601 agggaagacc acaagaagcc acccatggac tcccctgctg tgaggcagaa gcaagtaaca
     6661 actgggtcag aggtgtccac aaggcagaag ctccttctcc cagaacctgt tgtggtgccc
     6721 aacttctttt tgcctcccca gcaacttgag gcctctctac gcatgatctc acactctcca
     6781 gctttgccgc caccagccac agctgaccag gacaagagtg aggctaccac aggagccctt
     6841 gcccaaaggc cttgtcgccc cagaccttac tcactccctc ccaaccttcc tgaggaagag
     6901 acacgaagga ttgcacggat attttcttcc caatattccc aaaagactga tgaagcctga
     6961 gggaagtggc taccagccaa cctctcagct ctgttcagct tgcaagagac accaggtctg
     7021 tttccctcgg catcctgggg ccactaccat caccctgttc cacaggtatc ttcagaccta
     7081 gtcagctaag accagaggag tgtcccgagc cacctagcag ctgcctacca ggacctcagc
     7141 ttccttctgg aa
//
