LOCUS       NM_001011996            3367 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus C2CD2-like (C2cd2l), mRNA.
ACCESSION   NM_001011996 XM_217129
VERSION     NM_001011996.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3367)
  AUTHORS   Lees,J.A., Messa,M., Sun,E.W., Wheeler,H., Torta,F., Wenk,M.R., De
            Camilli,P. and Reinisch,K.M.
  TITLE     Lipid transport by TMEM24 at ER-plasma membrane contacts regulates
            pulsatile insulin secretion
  JOURNAL   Science 355 (6326) (2017)
   PUBMED   28209843
REFERENCE   2  (bases 1 to 3367)
  AUTHORS   Pottekat,A., Becker,S., Spencer,K.R., Yates,J.R. 3rd, Manning,G.,
            Itkin-Ansari,P. and Balch,W.E.
  TITLE     Insulin biosynthetic interaction network component, TMEM24,
            facilitates insulin reserve pool release
  JOURNAL   Cell Rep 4 (5), 921-930 (2013)
   PUBMED   24012759
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085925.1.
            
            [WARNING] On Aug 7, 2024 this sequence was replaced by
            NM_001011996.2.
            
            On Feb 11, 2005 this sequence version replaced XM_217129.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085925.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3367
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..3367
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /note="C2CD2-like"
                     /db_xref="GeneID:300666"
                     /db_xref="RGD:1310281"
     exon            1..711
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     CDS             358..2478
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /note="transmembrane protein 24; C2 domain-containing
                     protein 2-like; C2 calcium-dependent domain containing
                     2-like"
                     /codon_start=1
                     /product="phospholipid transfer protein C2CD2L"
                     /protein_id="NP_001011996.1"
                     /db_xref="GeneID:300666"
                     /db_xref="RGD:1310281"
                     /translation="MDPDWGQRDVGWAALLVLFAASLLTVLGWLLQYARGLWLSRAGG
                     GRDSRPASAAEPGGSLRELGVWRSLLRLRATRSSAPEEAGVRGLLASLFAFKSFRENW
                     QRAWVRALNEQACRDGSSIQIAFEEIPQLPPRASISHVTCVDQSERTMVLHCQLAAEE
                     VRFPISVTQQSPAAVSMETYHVTLTLPPTQLEVSLEEIPDEGLLVSWAFTDRPDLSLK
                     VLPKSQTRERDEEQPELSTVEELIKDAIVSTQPAMMVNLRACSAPGGLVPSEKPPTMS
                     QAQPSIPRPTRLFLRQLRASHLGSELGGTEELCCAAELDNPMQQKWTKPTRAGSEVEW
                     AEDLALDLGPQSRELTLKVLRSSSCGDAELLGQATLPVGSPSKPLSRRQVCPLTPGPG
                     KSLSPAAIVTVELHYEQGSPRNLGTPTSSTPRPSITPTKKIELDRTIMPDGTIVTTVT
                     TVQSRPRVDGKLDSPSRSPSKVEVTEKMTTVLSESSGPSNASHSSSRESHLSNGLDPV
                     AETAIRQLTEPSGRAAKKTPTKRSTLIISGVSKVPIAQDELALSLGYAASLEASMQDD
                     AGASGGPSSPPSDPSATSPGPVDALSSPTSVQEADETTRSDISERPSVDDVESETGST
                     GALETRSLKDHKVSFLRSGTKLIFRRRPRQKEAGLSQSHDDLSNTTATPSVRKKAGSF
                     SRRLIKRFSFKSKPKANGNPSPQL"
     exon            712..807
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            808..927
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1038
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1155
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1267
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1376
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1441
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1569
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1570..1744
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1846
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..1980
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2266
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..3338
                     /gene="C2cd2l"
                     /gene_synonym="Tmem24"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggagccggt gccggcccgc gagccccggt gtctccgcag actggtctct gccggtgtcc
       61 ggcgggggcc caagccgtgg gaggagtcgg gtgctagctg gagtctagct ggggtcacaa
      121 cgccggtgtc agggacccgg atctccggct acggagacag agcccgagcg tcgcgacccc
      181 ggagaacctc ttctctatcg gtggcaccga ctggtcctag gatctcggcg gcgccggaga
      241 gtcccggagc ccgcgctctc agccccgggg gagctcgccc acgccccacg gtccatccgg
      301 gccatgctcc cccggggcag cggctgagcc cgagccggga ccagagcccg cgggagcatg
      361 gatccagact gggggcagcg ggatgtgggc tgggcggccc tgctggtcct cttcgccgcc
      421 tcgctgctca cggtattggg ctggttgctg cagtatgccc ggggtttgtg gctgtcgcga
      481 gccggtgggg gccgagactc tcgacccgct tcagctgccg agcccggggg ttcattgcgc
      541 gagctgggtg tgtggcgttc gctgctgcgt ttgcgggcga cccggagcag cgcccccgag
      601 gaagccggcg tacggggcct cctggcttcg ctctttgcct tcaagtcttt ccgggagaac
      661 tggcaacggg cttgggtgcg agccttgaat gagcaggcct gcagggacgg gagctccatc
      721 caaatcgcct ttgaggagat accccaactc ccaccaagag ccagcattag tcatgtgacc
      781 tgcgttgacc aatcagagcg taccatggtg ctgcactgcc agctggctgc tgaggaggtg
      841 cgcttcccca tctccgtgac ccagcagtcc cccgctgccg tctccatgga gacctaccac
      901 gtcactctga cactgccacc aacacagttg gaagtcagcc ttgaggaaat ccctgatgag
      961 gggctgctgg tgtcctgggc cttcacggac cgcccagatc tcagcctgaa ggtgcttccc
     1021 aagtctcaga ctagggagag agatgaggaa caaccagagc tttcaacagt tgaggaactg
     1081 atcaaggacg ctatcgtcag cactcagccc gccatgatgg tcaacctcag ggcctgctct
     1141 gccccaggag gcctggtacc cagtgagaag ccacccacga tgtcccaggc ccagccatcc
     1201 atccccagac ctacccgact attcttacgg cagcttcgag catctcacct gggaagtgag
     1261 ctaggaggta ctgaggaact gtgctgtgct gctgagcttg acaaccccat gcaacagaag
     1321 tggaccaaac ccacaagggc tggctctgag gtggaatggg cagaggattt agctctggat
     1381 ctgggtcccc agagccggga gctgaccctc aaagtgctca ggagcagcag ttgtggagat
     1441 gctgaactcc ttggccaagc cacactgcct gtgggctcac cttccaaacc actgtcacgg
     1501 aggcaagtgt gtccactgac tccagggccc gggaaatccc tgagcccagc ggccatcgtg
     1561 acagtggagc tacactatga gcagggctct cctcggaatc tgggcacgcc cacctcttcc
     1621 acccctcgcc ccagcatcac acccaccaag aagattgagt tggaccggac catcatgcct
     1681 gatggcacaa tcgtcaccac tgttactact gtgcagtccc gcccccgtgt agatggcaaa
     1741 ctagactccc cctcccgctc cccgtccaag gtggaggtga ctgagaagat gacaactgtg
     1801 ctgagtgaga gcagcggccc cagcaatgcc tcccacagta gcagccggga gagccacctt
     1861 tccaatggct tggatccagt agcagagaca gcaatccgcc agctgacgga gcccagtggg
     1921 cgggcagcca agaagacacc caccaagcgc agcacgctca tcatctctgg tgtttccaag
     1981 gtgcccatcg ctcaggacga gttggcactc tccttgggtt atgcagcatc tctggaagcc
     2041 tcaatgcaag atgatgcagg agccagtggt ggtccttcat cacctccctc agacccctca
     2101 gccacatccc caggacccgt tgatgctctc tccagtccca caagtgtcca ggaagcagac
     2161 gagacaacac gttcagacat ttctgagagg ccgtcggtgg atgatgttga gtcagaaaca
     2221 gggtctactg gtgccctgga gacccgaagc ctcaaggatc acaaagtgag tttcctgcga
     2281 agtggcacta agctcatctt ccgccggcgg ccccgacaga aggaagcggg tctgagccag
     2341 tcgcacgatg acctgtccaa cacaacagcc acacctagtg tccggaagaa ggctggcagc
     2401 ttttcccgtc gccttatcaa gcgtttttcc ttcaagtcca aacccaaggc caatggcaac
     2461 cctagccccc agctctgaga gctcctgaac taggagaggg caagagttct cttagtttgt
     2521 cccccacatc cccttctgta ccccttcttg gatccccagt gctgggacca ggaaagccct
     2581 tgggttatag gaaaccccag cactctgggc tgtggggtta gcgggaaggg tgtctcacat
     2641 gggaagcatt tgagaggcaa cagttgttgc tgtggacata ggagagtttg gcagctgaga
     2701 gtaaagggca ggctctgtct ctcttgtgtg gacattcttc agaagcctct gcagtctgct
     2761 ggtactgccc ccagagggga gtccagagca ctctcttcag cagatccttc tcccttattt
     2821 attctctttt ctatttatat atgtggtcta gagcccttgg caaacagatg atagagggca
     2881 tctctcccag gtgacccttt tctgtcccag gagggtaagg caattcccag gacaggtttc
     2941 tacacctccc ttgggagtcc tcttttagac cagcaccgat gtctgtctgc cttcagaaga
     3001 cattggcaga tcataggaag ccggcctagt gcccgggatg gggggcaggc actccccacc
     3061 tccctacctc ccacacgcac cttgtctctc cttccccttt attaccattt tgtacttgat
     3121 accttctcca tgagcagtgg cgcagttgga aggaaggagc caggaagctg ggagcaagcc
     3181 ttctttccct agagagatgg ctttaggagc tttagacagt atggtcataa agcaaggttg
     3241 cacctctata tgttgggaga tgatgatgat gatgtccatt gctgtgtgat ggcttggaat
     3301 ttaatttatt taattaaaat caaattggaa tttacaaaaa aaaaaaaaaa aaaaaaaaaa
     3361 aaaaaaa
//
