LOCUS       NM_001002804            2921 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus complement C1r subcomponent like (C1rl), mRNA.
ACCESSION   NM_001002804 XM_579080
VERSION     NM_001002804.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2921)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   2  (bases 1 to 2921)
  AUTHORS   Wicher,K.B. and Fries,E.
  TITLE     Prohaptoglobin is proteolytically cleaved in the endoplasmic
            reticulum by the complement C1r-like protein
  JOURNAL   Proc Natl Acad Sci U S A 101 (40), 14390-14395 (2004)
   PUBMED   15385675
REFERENCE   3  (bases 1 to 2921)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
REFERENCE   4  (bases 1 to 2921)
  AUTHORS   Circolo,A., Garnier,G. and Volanakis,J.E.
  TITLE     A novel murine complement-related gene encoding a C1r-like serum
            protein
  JOURNAL   Mol Immunol 39 (14), 899-906 (2003)
   PUBMED   12686506
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 3, 2020 this sequence version replaced NM_001002804.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.14933.1,
                                           SRR26643299.20989.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               JAXUCZ010000004.1  159080495-159080604
            111-339             JAXUCZ010000004.1  159081143-159081371
            340-526             JAXUCZ010000004.1  159091883-159092069
            527-634             JAXUCZ010000004.1  159093419-159093526
            635-709             JAXUCZ010000004.1  159093621-159093695
            710-2921            JAXUCZ010000004.1  159094855-159097066
FEATURES             Location/Qualifiers
     source          1..2921
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..2921
                     /gene="C1rl"
                     /note="complement C1r subcomponent like"
                     /db_xref="GeneID:408246"
                     /db_xref="RGD:1302936"
     exon            1..110
                     /gene="C1rl"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..1497
                     /gene="C1rl"
                     /EC_number="3.4.21.41"
                     /note="complement C1r subcomponent-like protein; C1r-LP;
                     C1r-like protein; complement component 1, r
                     subcomponent-like"
                     /codon_start=1
                     /product="complement C1r subcomponent-like protein
                     precursor"
                     /protein_id="NP_001002804.2"
                     /db_xref="GeneID:408246"
                     /db_xref="RGD:1302936"
                     /translation="MSGSRGLVPELENNLWSSPNTSCVGKMCWLLLWGILHTCPTQAS
                     VLLAQQFPQQLTSPGYPEPYIKGQESHADIEAPEGFAVRLIFQDFDLEPSPGCEGDSV
                     TISTRGTDATRLCGQQGSSLGSPPNQMEFVSSGRSLRLTFRAHSSKNKVTHLHKGFLA
                     LYQAIAVSQPNGDAEAFTTPGANPPEIQNHCPGPYYKEEQTGTLSCPSSRKWKDRQRG
                     EEVPECVPVCGRPVVPIAENPNTFGSSRAKPGNFPWQAFTSIYGRGGGALLGDRWILT
                     AAHTIFPKDSIYLRKNKTVNVFLGHTDVDELLKLGNHPVRRVVVHPDYRQEESHNFDG
                     DIALLELEHRVPLGPSLLPVCLPDNETLYHSGLWGYISGFGVEMGWLTTKLKYSKLPV
                     APREACEAWLRQRQRTEVFSDNMFCVGEEMQVNSVCQGDSGSVYVVWDDRALRWVATG
                     IVSWGVGCGKGYGFYTKVLSYVDWIKGVIECKDRCPEA"
     exon            111..339
                     /gene="C1rl"
                     /inference="alignment:Splign:2.1.0"
     exon            340..526
                     /gene="C1rl"
                     /inference="alignment:Splign:2.1.0"
     exon            527..634
                     /gene="C1rl"
                     /inference="alignment:Splign:2.1.0"
     exon            635..709
                     /gene="C1rl"
                     /inference="alignment:Splign:2.1.0"
     exon            710..2921
                     /gene="C1rl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctgggcta cgcaccctag ccagttccag atgtcagggt ccagaggcct ggtcccagag
       61 ctggagaaca acctatggag ttctcccaac acaagctgcg tgggcaagat gtgctggttg
      121 ctcctttggg gaatcctcca tacttgcccc acacaggcct ctgtgctttt agcccagcag
      181 tttcctcagc aactgacatc ccccggatac ccagagccat atatcaaagg ccaggagagc
      241 catgctgaca tcgaggcccc ggaggggttt gccgtgagac tgatcttcca ggactttgat
      301 ctggagccgt ccccaggctg tgaaggcgac tctgtcacca tttcaaccag aggaacagat
      361 gcaacccggc tgtgtgggca gcaaggttcc tctctgggga gccctcccaa tcaaatggag
      421 tttgtatcct ccgggaggag ccttcggctg accttccggg cacactcctc caagaacaaa
      481 gtcacacacc tccacaaagg cttcctggct ctctaccaag ccatagctgt gagccaaccc
      541 aatggggacg ctgaggcttt caccacacct ggagccaacc ctcccgagat tcagaaccac
      601 tgcccaggtc cctattataa ggaagaacag acagggacac ttagctgccc atcctctcgg
      661 aagtggaagg acagacagcg tggagaagag gttcctgagt gtgtgccggt ctgtggaaga
      721 ccagttgtcc ccattgccga gaacccaaac acttttggtt cttccagagc caagcctggc
      781 aacttcccct ggcaagcctt caccagtatc tatggccgtg ggggcggagc cctgctgggt
      841 gacagatgga tcctgacggc tgcccatacc atcttcccca aggatagcat ctatctcaga
      901 aagaacaaga ctgtgaatgt gtttctgggt cacacagacg tagacgagct gctgaaactg
      961 gggaaccatc ctgtccgaag ggtggtggtt cacccagact accgccaaga ggagtcccac
     1021 aactttgatg gggatatcgc cctcctggag cttgagcaca gggtccctct ggggcccagt
     1081 ctcctcccgg tctgtctgcc ggacaacgag accctctacc acagcggcct gtggggttac
     1141 atcagtgggt tcggtgtgga gatgggctgg ttgacgacaa agttgaaata ctcaaagctg
     1201 cctgtagctc cccgggaggc ctgtgaagcc tggctccgcc agaggcagcg aactgaggtg
     1261 ttttctgaca atatgttctg tgtcggggaa gagatgcagg tcaacagtgt ctgccaggga
     1321 gacagtggca gcgtctacgt ggtgtgggac gaccgtgctc ttcgctgggt ggccacgggc
     1381 attgtatcct ggggcgtcgg gtgtggcaag gggtacggct tctacaccaa agtgctcagc
     1441 tacgtggatt ggattaaggg ggtgattgaa tgtaaagacc gatgcccgga ggcctgagca
     1501 gtggccctca agaggtccca gctaagaatg ggcaggagtg aggatgcact tgaagccagg
     1561 ggcccctatt taagtcattg gctcagcaac ccattgccaa gagaaagccc cgcctcctcg
     1621 agcttacacc accccaaacg agatgcagta cccgcttctc acctcctgct ctcctgggct
     1681 ttataccagg ggaaccctgc aaatgtatgc aacgtttgct tagaacatct ttctgttcga
     1741 aacaagtcag gacttccctc tgtagccagg atggacacaa actcagggca atgttcctgc
     1801 ttcggcctcc caaacactgg ggattacaag catgtacacc tggcatcatc accatgtgtg
     1861 tcgtttttaa ttccccagcc tcagctatgg acagttcctt ctgtatttac tcgtggaatt
     1921 gtgtttctga gatattccag agacccgtcc ttcaaatacg cagagccacc agctttgccc
     1981 cttaccccag cttctacagg aaatcttagc gatactccct tttcatttca catctaccgt
     2041 aagtcaggag tctcacccaa tcctccctcc gcactggcag agggtgtgtc atctgtcatc
     2101 catgtctcac agcgaggaac tggaagctcc caaagattcg gtggcttgcg gaagtcccac
     2161 agctgagctt cattgattga ggcttcattc cgcccagcac actctcaggg attcctctca
     2221 gttgccctgg agacctacct tagcatcccc caccccccca ccccaccccc accccacccc
     2281 ccacccccat tcctaccccc caccccccca cccccaccac ccaccaccac ccctaccccc
     2341 gtccccagac tcggtccctg ggaaggcctg tttcactgaa gactgtacca ccagctcaca
     2401 ctttcctgct ggccctcgtc accagggcat cacaagcctg agaagatgag ctctttaatt
     2461 tgtacggaag atttggaatg atttacacta aaagacaaaa ataaaagagt tcagtgacaa
     2521 tagactgtga ataccataaa aagaaaaaaa aagaagaagt acgttagtgt tgagatgaag
     2581 gttctctatt agcaaaagtt aaatttatct ttgaaaaaaa aaaaaaaaaa aacagcagca
     2641 tccaagctaa gcacatagta cacactaaaa tcccagtcac gtgggaggct gaggcagaag
     2701 gatcataagt tcaaggccag ctttgatctc atctcaaagt taacaataaa taaataacag
     2761 tgtggtggtg gctcaggcct ttaatcccaa cactggggga ggttcaaggc cagcctggtc
     2821 tacagagtca gttccaggac tttcaaggct acacaaagaa attctgtctt gaaaatcaat
     2881 caatcaatca ataaataaat aaataaatgg cagaatataa a
//
