LOCUS       NM_001107221            1336 bp    mRNA    linear   ROD 21-MAR-2025
DEFINITION  Rattus norvegicus C1q and TNF related 7 (C1qtnf7), transcript
            variant 1, mRNA.
ACCESSION   NM_001107221 XM_001060132 XM_223507
VERSION     NM_001107221.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Bi,J., Duan,Y., Wang,M., He,C., Li,X., Zhang,X., Tao,Y., Du,Y. and
            Liu,H.
  TITLE     Deletion of large-conductance calcium-activated potassium channels
            promotes vascular remodelling through the CTRP7-mediated PI3K/Akt
            signaling pathway
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 54 (12), 1-11 (2022)
   PUBMED   36514218
  REMARK    GeneRIF: Deletion of large-conductance calcium-activated potassium
            channels promotes vascular remodelling through the CTRP7-mediated
            PI3K/Akt signaling pathway.
REFERENCE   2  (bases 1 to 1336)
  AUTHORS   Wong,G.W., Krawczyk,S.A., Kitidis-Mitrokostas,C., Revett,T.,
            Gimeno,R. and Lodish,H.F.
  TITLE     Molecular, biochemical and functional characterizations of C1q/TNF
            family members: adipose-tissue-selective expression patterns,
            regulation by PPAR-gamma agonist, cysteine-mediated
            oligomerizations, combinatorial associations and metabolic
            functions
  JOURNAL   Biochem J 416 (2), 161-177 (2008)
   PUBMED   18783346
REFERENCE   3  (bases 1 to 1336)
  AUTHORS   Rohrbach,S., Aurich,A.C., Li,L. and Niemann,B.
  TITLE     Age-associated loss in adiponectin-activation by caloric
            restriction: lack of compensation by enhanced inducibility of
            adiponectin paralogs CTRP2 and CTRP7
  JOURNAL   Mol Cell Endocrinol 277 (1-2), 26-34 (2007)
   PUBMED   17716811
  REMARK    GeneRIF: The purpose of the current study was to investigate
            age-dependent effects of caloric restriction on the release of
            adiponectin, expression and activation of adiponectin-related
            signaling and on parameters of altered insulin sensitivity.
REFERENCE   4  (bases 1 to 1336)
  AUTHORS   Wong,G.W., Wang,J., Hug,C., Tsao,T.S. and Lodish,H.F.
  TITLE     A family of Acrp30/adiponectin structural and functional paralogs
  JOURNAL   Proc Natl Acad Sci U S A 101 (28), 10302-10307 (2004)
   PUBMED   15231994
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473963.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001060132.1, XM_223507.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM031994.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760475
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1336
                     /gene="C1qtnf7"
                     /gene_synonym="Adig; Ctrp7"
                     /note="C1q and TNF related 7"
                     /db_xref="GeneID:305423"
                     /db_xref="RGD:1306978"
     exon            1..61
                     /gene="C1qtnf7"
                     /gene_synonym="Adig; Ctrp7"
                     /inference="alignment:Splign:2.1.0"
     exon            62..307
                     /gene="C1qtnf7"
                     /gene_synonym="Adig; Ctrp7"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..939
                     /gene="C1qtnf7"
                     /gene_synonym="Adig; Ctrp7"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; complement C1q tumor necrosis factor-related
                     protein 7; C1q and tumor necrosis factor related protein
                     7; adiponectin g"
                     /codon_start=1
                     /product="complement C1q tumor necrosis factor-related
                     protein 7 isoform 1 precursor"
                     /protein_id="NP_001100691.1"
                     /db_xref="GeneID:305423"
                     /db_xref="RGD:1306978"
                     /translation="MIVLLYVTSLAICASGQPRGNQAKGESYSPRYICSIPGLPGPPG
                     PPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLKGKTGPLGLAGEKGDQGETGK
                     KGPIGPEGEKGEVGPAGPPGPKGDRGDQGDPGLPGVCRCGSIVLKSAFSVGITTSYPE
                     ERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQYRI
                     RTFDANTGNHDVASGSTVIYLQPEDEVWLEIFFNDQNGLFSDPGWADSLFSGFLLYVD
                     TDYLDSISEDDEL"
     exon            308..1336
                     /gene="C1qtnf7"
                     /gene_synonym="Adig; Ctrp7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaaagatc ctgacttttg tacactggga atcctgcagc aacctaccct cccagagcac
       61 gagcccaaga tgattgtcct gctctacgtg acaagtcttg ccatctgtgc aagtggacaa
      121 cctcggggca atcaggctaa gggggagagc tactctccaa ggtacatctg cagcatccct
      181 ggcttacctg ggcccccagg tcctcctgga gcaaatggct cccctggacc ccatggtcgc
      241 attggccttc ctggaaggga tggtagagat ggcagaaaag gagagaaggg ggaaaagggc
      301 actgcaggtc taaaaggtaa gactggaccc ctgggccttg ctggtgagaa aggagaccaa
      361 ggagagactg ggaagaaagg acccatagga ccagagggtg agaaaggaga agttggtcca
      421 gctgggcctc ctgggccaaa gggagaccga ggagatcaag gggacccagg actgcctgga
      481 gtgtgcagat gtggaagcat cgtgctcaaa tctgcctttt cagttggcat cacaaccagc
      541 tacccagaag aaagactacc catcatattt aacaaagtcc tcttcaatga gggggagcac
      601 tacaaccctg caacagggaa gttcatttgt gctttcccag ggatctatta tttttcttat
      661 gatatcacgt tggccaataa gcacctagcc atcgggctgg tgcacaatgg gcagtaccgg
      721 ataaggacct ttgatgccaa cacagggaac cacgatgtgg cttcagggtc cacagtcatc
      781 tacctgcagc cagaagatga ggtctggctg gagattttct tcaatgacca gaatggcctc
      841 ttctcagatc caggctgggc agacagcttg ttctccgggt ttctcctcta tgttgataca
      901 gattacctgg attctatatc agaagacgat gagttgtgat ccggactgca ggcctgaatg
      961 ttgcaacatg agttccacag tggcttacac tctgatctaa tctggagtgc tggaaggtgg
     1021 agcaagtgat actgggattc agaacacatt ttttttacag atggctctgg cagagttaac
     1081 aaaataagac aaaccaccaa ccagttgaaa tcacaccaaa atgaacggca tgcaataacc
     1141 ccagacatgg accccctgaa gtaaagatcc taaatattta agcaaattaa gatgatgtta
     1201 acaaatttga atgcccttgg caatacaacc agcgggtagt gacactgcct cattaaatat
     1261 tcataaaact ccagttgtgt ttgttattta gaatagtcat aacattttag tggaatttgt
     1321 tgacaattct caggag
//
