LOCUS       NM_001108000            1313 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus C1q and TNF related 12 (C1qtnf12), mRNA.
ACCESSION   NM_001108000 XM_001077774 XM_233720
VERSION     NM_001108000.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Zhou MQ, Jin E, Wu J, Ren F, Yang YZ and Duan DD.
  TITLE     CTRP12 Ameliorated Lipopolysaccharide-Induced Cardiomyocyte Injury
  JOURNAL   Chem Pharm Bull (Tokyo) 68 (2), 133-139 (2020)
   PUBMED   32009080
  REMARK    GeneRIF: C1qtnf12 ameliorated injury in
            lipopolysaccharide-stimulated cardiomyocytes in an NRF2-dependent
            manner.
REFERENCE   2  (bases 1 to 1313)
  AUTHORS   Wei Z, Peterson JM, Lei X, Cebotaru L, Wolfgang MJ, Baldeviano GC
            and Wong GW.
  TITLE     C1q/TNF-related protein-12 (CTRP12), a novel adipokine that
            improves insulin sensitivity and glycemic control in mouse models
            of obesity and diabetes
  JOURNAL   J Biol Chem 287 (13), 10301-10315 (2012)
   PUBMED   22275362
REFERENCE   3  (bases 1 to 1313)
  AUTHORS   Enomoto T, Ohashi K, Shibata R, Higuchi A, Maruyama S, Izumiya Y,
            Walsh K, Murohara T and Ouchi N.
  TITLE     Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that
            improves glucose metabolism
  JOURNAL   J Biol Chem 286 (40), 34552-34558 (2011)
   PUBMED   21849507
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_233720.4, XM_001077774.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760396,
                              SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1313
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /note="C1q and TNF related 12"
                     /db_xref="GeneID:313774"
                     /db_xref="RGD:1307059"
     exon            1..421
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
     CDS             263..1189
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /note="C1q domain containing 2; protein FAM132A; adipolin;
                     family with sequence similarity 132, member A; C1q and
                     tumor necrosis factor related protein 12"
                     /codon_start=1
                     /product="adipolin precursor"
                     /protein_id="NP_001101470.1"
                     /db_xref="GeneID:313774"
                     /db_xref="RGD:1307059"
                     /translation="MWAWGWAAAALLWLQTAGVRARQELKKPRQLVVRVDSPNITTSS
                     HEGFPGSIKPPEASGPELSDAHMTWLNFVRRPDDGASRKRCRGRDKKSRGLSGLPGPP
                     GPPGPPGPPGSPGLEVTPEALLQEFQEMLKEAAELRFSGIPDSLLPQEPRQRLVVEAF
                     HCRLKGPVTVDKKTLVELQGFQAPTTQGAFLRGSGLSLSLGRFTAPVSAIFQFSASLH
                     VDHSELQGRGRLRTRDTVRVLICIESLCHRHTSLEAVSGLESNSRVFTVQVQGLLYLQ
                     SGQYVSVFVDNSSGAVLTIQNGSSFSGMLLGT"
     exon            422..538
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
     exon            539..659
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
     exon            660..811
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
     exon            812..920
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1011
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1090
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1313
                     /gene="C1qtnf12"
                     /gene_synonym="C1qdc2; Fam132a; RGD1307059"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgagtcctcc ccttggagcc tgagaggctt aggaaggaag gaggtctctt ttggtggcag
       61 agttgccggc aagggcactg agcaggagga taggacggca aagacgaaga gttctgactc
      121 ctcctgcaga catgcaccag cggctgctgg gctcgtccct gggcctcgcc cccgcgcagg
      181 ggctctgaat gcctgccgcc gcccccataa gcacactggc cggggctcct atccctaagc
      241 ctctacttgc ggagactgag ccatgtgggc ttggggctgg gctgcggcag ctctcctctg
      301 gctacagact gcaggagtcc gggcacgaca ggaactcaag aagcctcggc agctggttgt
      361 gcgtgtggat tctcccaata ttaccacatc cagccatgag ggattcccag gctccatcaa
      421 gccgccggaa gcctctggac ctgagctctc agatgcccac atgacatggc tgaactttgt
      481 ccgacggccg gatgatgggg cctctagaaa acggtgccgt ggccgggaca agaagtcgcg
      541 aggcctctca ggtctcccag gacccccagg accccctggc cctcctggtc cacctggttc
      601 ccctggtttg gaagttaccc cagaggcctt gctgcaggaa tttcaggaga tgctgaaaga
      661 ggccgcagaa cttcgattct cagggatacc ggactcgctg ttaccccagg aacccaggca
      721 gcggttggtg gtcgaggcct tccattgccg tttgaaaggc cctgtgacgg tagacaagaa
      781 gactctggtg gaactgcaag gattccaggc tcctactacc cagggtgcct tcctgcgggg
      841 atctggcctg agcctgtcct tgggccgatt tacagcgcca gtctctgcca tcttccagtt
      901 ttctgccagc ctgcacgtgg accacagtga actgcagggc agaggccggt tacgtacccg
      961 ggacacggtc cgtgtcctca tctgtattga gtccttgtgt caccgtcata cgtccctgga
     1021 ggctgtgtca ggcctggaga gcaacagcag ggtcttcacc gtgcaggttc aggggctgct
     1081 gtatttacag tctggacagt atgtctctgt gttcgtggac aacagttctg gggcagtcct
     1141 caccatccag aacggctcca gcttctccgg gatgcttttg ggtacgtaga ggaactgaag
     1201 agatgattga ggattgcaga gccaacacct tgcttcttag aggagctgaa aaggactact
     1261 ccccctttta atagttttca tagcaataaa gaactccaaa cgtcttcatc acc
//
