LOCUS       NM_001007675            1561 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus C1q and TNF related 1 (C1qtnf1), mRNA.
ACCESSION   NM_001007675 XM_221139
VERSION     NM_001007675.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1561)
  AUTHORS   Wong,G.W., Krawczyk,S.A., Kitidis-Mitrokostas,C., Revett,T.,
            Gimeno,R. and Lodish,H.F.
  TITLE     Molecular, biochemical and functional characterizations of C1q/TNF
            family members: adipose-tissue-selective expression patterns,
            regulation by PPAR-gamma agonist, cysteine-mediated
            oligomerizations, combinatorial associations and metabolic
            functions
  JOURNAL   Biochem J 416 (2), 161-177 (2008)
   PUBMED   18783346
REFERENCE   2  (bases 1 to 1561)
  AUTHORS   Jeon,J.H., Kim,K.Y., Kim,J.H., Baek,A., Cho,H., Lee,Y.H., Kim,J.W.,
            Kim,D., Han,S.H., Lim,J.S., Kim,K.I., Yoon,D.Y., Kim,S.H., Oh,G.T.,
            Kim,E. and Yang,Y.
  TITLE     A novel adipokine CTRP1 stimulates aldosterone production
  JOURNAL   FASEB J 22 (5), 1502-1511 (2008)
   PUBMED   18171693
REFERENCE   3  (bases 1 to 1561)
  AUTHORS   Kim,K.Y., Kim,H.Y., Kim,J.H., Lee,C.H., Kim,D.H., Lee,Y.H.,
            Han,S.H., Lim,J.S., Cho,D.H., Lee,M.S., Yoon,S., Kim,K.I.,
            Yoon,D.Y. and Yang,Y.
  TITLE     Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1
            expression in adipose tissue
  JOURNAL   FEBS Lett 580 (16), 3953-3960 (2006)
   PUBMED   16806199
  REMARK    GeneRIF: These findings indicate that CTRP1 expression may be
            associated with a low-grade chronic inflammation status in adipose
            tissues.[Ctrp1]
REFERENCE   4  (bases 1 to 1561)
  AUTHORS   Lasser,G., Guchhait,P., Ellsworth,J.L., Sheppard,P., Lewis,K.,
            Bishop,P., Cruz,M.A., Lopez,J.A. and Fruebis,J.
  TITLE     C1qTNF-related protein-1 (CTRP-1): a vascular wall protein that
            inhibits collagen-induced platelet aggregation by blocking VWF
            binding to collagen
  JOURNAL   Blood 107 (2), 423-430 (2006)
   PUBMED   16195328
REFERENCE   5  (bases 1 to 1561)
  AUTHORS   Wong,G.W., Wang,J., Hug,C., Tsao,T.S. and Lodish,H.F.
  TITLE     A family of Acrp30/adiponectin structural and functional paralogs
  JOURNAL   Proc Natl Acad Sci U S A 101 (28), 10302-10307 (2004)
   PUBMED   15231994
REFERENCE   6  (bases 1 to 1561)
  AUTHORS   Innamorati,G., Whang,M.I., Molteni,R., Le Gouill,C. and
            Birnbaumer,M.
  TITLE     GIP, a G-protein-coupled receptor interacting protein
  JOURNAL   Regul Pept 109 (1-3), 173-179 (2002)
   PUBMED   12409230
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083720.1.
            
            On Nov 29, 2004 this sequence version replaced XM_221139.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083720.1, FQ209955.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1561
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.3"
     gene            1..1561
                     /gene="C1qtnf1"
                     /gene_synonym="Ctrp1"
                     /note="C1q and TNF related 1"
                     /db_xref="GeneID:303701"
                     /db_xref="RGD:1359204"
     exon            1..261
                     /gene="C1qtnf1"
                     /gene_synonym="Ctrp1"
                     /inference="alignment:Splign:2.1.0"
     exon            262..420
                     /gene="C1qtnf1"
                     /gene_synonym="Ctrp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..1111
                     /gene="C1qtnf1"
                     /gene_synonym="Ctrp1"
                     /note="complement C1q tumor necrosis factor-related
                     protein 1; C1q and tumor necrosis factor related protein
                     1"
                     /codon_start=1
                     /product="complement C1q tumor necrosis factor-related
                     protein 1 precursor"
                     /protein_id="NP_001007676.1"
                     /db_xref="GeneID:303701"
                     /db_xref="RGD:1359204"
                     /translation="MGSRGQGFMLGCCLLLAVTWGPVLSLVPRVQEEQQEWEETEELT
                     SPLDHVTRPEETHKRYSPSLREGLPTSRCYRCCDSNPPVYQTIPPPQINITILKGEKG
                     DRGDRGLQGKYGKIGSTGPRGHIGPKGQKGSMGAPGDHCKSQYAAFSVGRKKALHSND
                     YFQPVVFDTEFVNLYNHFNMFTGKFYCYVPGIYFFSLNVHTWNQKETYLHIMKNEEEV
                     VILYAQVSDRSIMQSQSLMLELREQDEVWVRLFKGERENAIFSDEFDTYITFSGYLVK
                     PASEP"
     exon            421..560
                     /gene="C1qtnf1"
                     /gene_synonym="Ctrp1"
                     /inference="alignment:Splign:2.1.0"
     exon            561..1535
                     /gene="C1qtnf1"
                     /gene_synonym="Ctrp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggcagct gaggagataa aggtgttggg actgctgtgg cttgcacttc ccacaccctt
       61 tcctccccct aaagcccccc cccggggggg ggactttttt ctccctaggg ctttctctct
      121 cagctttgac acgtctgtgc ttcccctctg acctagccta gaaaaaggct cagcccctgg
      181 gagatgcttt aagagaccac ttctcgagag ccctgagagg cgggaggatt cgattggcac
      241 agccggctca gctggaagga ggaagatggg ctcccgtgga cagggattca tgctgggatg
      301 ctgcctgctg ctggctgtca cctggggccc ggtcctgagc cttgtgccac gagttcagga
      361 ggaacaacag gagtgggaag agacagagga gctgacatct cccctggatc atgtgacaag
      421 gcctgaagaa acacacaaga ggtatagccc tagcctgcgt gagggcctcc ccacttcccg
      481 gtgctatcga tgctgtgatt ccaaccctcc agtataccag acaatccctc cgccccagat
      541 caacatcacc atcctaaaag gtgagaaagg agaccgaggg gatcgaggcc tgcaggggaa
      601 gtatggcaaa ataggttcta cgggtcccag gggccacatt ggccccaaag ggcagaaggg
      661 atctatggga gcccctgggg accactgcaa gagccagtac gcagccttct ctgtgggccg
      721 aaagaaggct ctgcacagta acgactactt ccagcctgtg gtcttcgaca cggagtttgt
      781 gaacctctac aatcacttca acatgttcac cgggaagttc tactgctacg tgcccggcat
      841 ctacttcttc agcctcaacg tgcacacgtg gaaccagaag gagacctacc tgcacatcat
      901 gaagaacgag gaggaggtcg tgatcctgta tgcgcaggtg agcgaccgca gcatcatgca
      961 gagtcagagc ctgatgctgg agctgcgaga gcaggatgag gtatgggtgc gcctcttcaa
     1021 gggcgagcgt gagaacgcca tcttcagtga cgagttcgac acctacatca ccttcagcgg
     1081 ctacctggtc aagccggcct ccgagcccta gcggacaccc cttggagctt ccacggactt
     1141 ctgacctcct tgcctgtcac ctggcttatc cctgcattct acggacactg gagtcctgcc
     1201 ccaggctgac cccgttacct ctctcctcca tcccggcttc cttggccttg acttcctcag
     1261 ttttggtttt tgacaagatg cccttggcca ccgggaagcc caaaggtccc ggatctggct
     1321 gccgatggat gagatcattg ggcggggaga ctgtgtggac attgggggac ctccagcttc
     1381 tcctgtgtac acagccttag acgaccctgt gctgtgttgt cctgtggcca cagggtgttc
     1441 cagagcacag cccctgtgtg ttttcattcc tggacgcaag taagcaaagg tcgtgggttt
     1501 cttagggacg aagtaaagca gaaaagagaa agaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1561 a
//
