LOCUS       NP_942084                419 aa            linear   ROD 02-APR-2024
DEFINITION  eIF5-mimic protein 2 [Rattus norvegicus].
ACCESSION   NP_942084 XP_343573
VERSION     NP_942084.1
DBSOURCE    REFSEQ: accession NM_198789.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 419)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 419)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (residues 1 to 419)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (residues 1 to 419)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (residues 1 to 419)
  AUTHORS   Mitra,P., Vaughan,P.S., Stein,J.L., Stein,G.S. and van Wijnen,A.J.
  TITLE     Purification and functional analysis of a novel
            leucine-zipper/nucleotide-fold protein, BZAP45, stimulating cell
            cycle regulated histone H4 gene transcription
  JOURNAL   Biochemistry 40 (35), 10693-10699 (2001)
   PUBMED   11524015
REFERENCE   6  (residues 1 to 419)
  AUTHORS   Hoja,M.R., Wahlestedt,C. and Hoog,C.
  TITLE     A visual intracellular classification strategy for uncharacterized
            human proteins
  JOURNAL   Exp Cell Res 259 (1), 239-246 (2000)
   PUBMED   10942595
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061580.1.
            
            On Dec 17, 2003 this sequence version replaced XP_343573.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061580.1, SRR8487226.31180.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q31"
     Protein         1..419
                     /product="eIF5-mimic protein 2"
                     /note="basic leucine zipper and W2 domain-containing
                     protein 1"
                     /calculated_mol_wt=47912
     Region          1..26
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6P7P5.1)"
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0000250|UniProtKB:Q7L1Q6; propagated from
                     UniProtKB/Swiss-Prot (Q6P7P5.1)"
     Site            12
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q7L1Q6; propagated from
                     UniProtKB/Swiss-Prot (Q6P7P5.1)"
     Region          217..406
                     /region_name="W2_eIF5C_like"
                     /note="C-terminal W2 domain of the eukaryotic translation
                     initiation factor 5C and similar proteins; cd11560"
                     /db_xref="CDD:211398"
     Site            411
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q6P7P5.1)"
     Site            413
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q6P7P5.1)"
     CDS             1..419
                     /gene="Bzw1"
                     /coded_by="NM_198789.2:98..1357"
                     /db_xref="GeneID:363232"
                     /db_xref="RGD:735129"
ORIGIN      
        1 mnnqkqqkpt lsgqrfktrk rdekerfdpt qfqdciiqgl tetgtdleav akfldasgak
       61 ldyrryaetl fdilvaggml apggtladdm mrtdvcvfaa qedletmqaf aqvfnklirr
      121 ykylekgfed evkklllflk gfsesernkl amltgvllan gtlnasilns lynenlvkeg
      181 vsaafavklf kswinekdin avaaslrkvs mdnrlmelfp ankqsvehft kyfteaglke
      241 lseyvrnqqt igarkelqke lqeqmsrgdp fkdiilyvke emkknnipep vvigivwssv
      301 mstvewnkke elvaeqaikh lkqyspllaa fttqgqselt lllkiqeycy dnihfmkafq
      361 kivvlfykae vlseepilkw ykdahvakgk svfleqmkkf vewlknaeee seseaeegd
//
