LOCUS       NM_182674               1696 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus bystin-like (Bysl), mRNA.
ACCESSION   NM_182674
VERSION     NM_182674.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1696)
  AUTHORS   Badertscher,L., Wild,T., Montellese,C., Alexander,L.T., Bammert,L.,
            Sarazova,M., Stebler,M., Csucs,G., Mayer,T.U., Zamboni,N., Zemp,I.,
            Horvath,P. and Kutay,U.
  TITLE     Genome-wide RNAi Screening Identifies Protein Modules Required for
            40S Subunit Synthesis in Human Cells
  JOURNAL   Cell Rep 13 (12), 2879-2891 (2015)
   PUBMED   26711351
REFERENCE   2  (bases 1 to 1696)
  AUTHORS   Henras,A.K., Plisson-Chastang,C., O'Donohue,M.F., Chakraborty,A.
            and Gleizes,P.E.
  TITLE     An overview of pre-ribosomal RNA processing in eukaryotes
  JOURNAL   Wiley Interdiscip Rev RNA 6 (2), 225-242 (2015)
   PUBMED   25346433
  REMARK    Review article
REFERENCE   3  (bases 1 to 1696)
  AUTHORS   Zemp,I., Wandrey,F., Rao,S., Ashiono,C., Wyler,E., Montellese,C.
            and Kutay,U.
  TITLE     CK1delta and CK1epsilon are components of human 40S subunit
            precursors required for cytoplasmic 40S maturation
  JOURNAL   J Cell Sci 127 (Pt 6), 1242-1253 (2014)
   PUBMED   24424021
REFERENCE   4  (bases 1 to 1696)
  AUTHORS   Sloan,K.E., Mattijssen,S., Lebaron,S., Tollervey,D., Pruijn,G.J.
            and Watkins,N.J.
  TITLE     Both endonucleolytic and exonucleolytic cleavage mediate ITS1
            removal during human ribosomal RNA processing
  JOURNAL   J Cell Biol 200 (5), 577-588 (2013)
   PUBMED   23439679
REFERENCE   5  (bases 1 to 1696)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 1696)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   7  (bases 1 to 1696)
  AUTHORS   Adachi,K., Soeta-Saneyoshi,C., Sagara,H. and Iwakura,Y.
  TITLE     Crucial role of Bysl in mammalian preimplantation development as an
            integral factor for 40S ribosome biogenesis
  JOURNAL   Mol Cell Biol 27 (6), 2202-2214 (2007)
   PUBMED   17242206
REFERENCE   8  (bases 1 to 1696)
  AUTHORS   Aoki,R., Suzuki,N., Paria,B.C., Sugihara,K., Akama,T.O., Raab,G.,
            Miyoshi,M., Nadano,D. and Fukuda,M.N.
  TITLE     The Bysl gene product, bystin, is essential for survival of mouse
            embryos
  JOURNAL   FEBS Lett 580 (26), 6062-6068 (2006)
   PUBMED   17055491
REFERENCE   9  (bases 1 to 1696)
  AUTHORS   Ma,L., Yin,M., Wu,X., Wu,C., Yang,S., Sheng,J., Ni,H., Fukuda,M.N.
            and Zhou,J.
  TITLE     Expression of trophinin and bystin identifies distinct cell types
            in the germinal zones of adult rat brain
  JOURNAL   Eur J Neurosci 23 (9), 2265-2276 (2006)
   PUBMED   16706835
REFERENCE   10 (bases 1 to 1696)
  AUTHORS   Sheng,J., Yang,S., Xu,L., Wu,C., Wu,X., Li,A., Yu,Y., Ni,H.,
            Fukuda,M. and Zhou,J.
  TITLE     Bystin as a novel marker for reactive astrocytes in the adult rat
            brain following injury
  JOURNAL   Eur J Neurosci 20 (4), 873-884 (2004)
   PUBMED   15305856
  REMARK    GeneRIF: Bystin expressed by reactive astrocytes may be involved in
            astrocyte differentiation during the inflammatory processes
            following brain injury.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CV104390.1 and BC079030.1.
            
            On Jan 15, 2008 this sequence version replaced NM_182674.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079030.1, AY257675.4 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                CV104390.1         1-11
            12-1696             BC079030.1         1-1685
FEATURES             Location/Qualifiers
     source          1..1696
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..1696
                     /gene="Bysl"
                     /note="bystin-like"
                     /db_xref="GeneID:359727"
                     /db_xref="RGD:727959"
     exon            1..333
                     /gene="Bysl"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1379
                     /gene="Bysl"
                     /codon_start=1
                     /product="bystin"
                     /protein_id="NP_872615.3"
                     /db_xref="GeneID:359727"
                     /db_xref="RGD:727959"
                     /translation="MPKLKVTRGARNQERHAPLAEQILAGDAVRAGTREKRRRHGVEE
                     EEEYVGPRLSRRILQQARQQQEELETEHATGDRPAKPRERATRLGPGVPQDGSDEEDE
                     EWPTLEKAAKMTVVNHQAEVVVDPEDERAIEMFMNKNPPVRRTLADIIMEKLTEKQTE
                     VETVMSEVSGFPMPQLDPRVLEVYRGVREVLCKYRSGKLPKAFKIIPALSNWEQILYV
                     TEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALK
                     KALFKPGAWFKGILIPLCESGTCTLREAIIVGSIISKCSIPVLHSSAAMLKIAEMEYS
                     GASSIFLRLLLDKKYALPYRVLDALVFHFLAFRTEKRQLPVLWHQCLLTLAQRYKADL
                     ATEQKEALLELLRLQPHPQLSPEIRRELQSAVPRDVEDVVVTME"
     exon            334..496
                     /gene="Bysl"
                     /inference="alignment:Splign:2.1.0"
     exon            497..635
                     /gene="Bysl"
                     /inference="alignment:Splign:2.1.0"
     exon            636..769
                     /gene="Bysl"
                     /inference="alignment:Splign:2.1.0"
     exon            770..930
                     /gene="Bysl"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1033
                     /gene="Bysl"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1671
                     /gene="Bysl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaagcgcag tctcgtctct tagccggctt cacacgtgta aactttgtgg gcaagttttt
       61 cgacaaaaat gcccaaatta aaggtgacac gtggggccag aaatcaagag agacatgcac
      121 ctctggcgga gcagattctg gctggggacg cagtgcgtgc ggggacccga gaaaaacggc
      181 ggagacacgg ggtcgaagag gaggaagagt atgtgggacc ccggttgagc agacggattt
      241 tgcaacaagc ccggcagcag caggaggagc tcgagactga acacgcgact ggagatcggc
      301 cggcaaaacc gcgagagcgc gccacgcggc tggggccagg agtgccacag gatggatcgg
      361 atgaggagga tgaggaatgg cctaccctgg agaaggcagc caaaatgacc gtggtgaacc
      421 accaggcaga ggtagtggtg gaccctgaag atgaacgcgc cattgaaatg ttcatgaaca
      481 agaaccctcc tgtcaggcgc accctggctg acatcatcat ggagaagctg actgagaagc
      541 agacagaggt ggagactgtc atgtcagaag tatcgggctt ccctatgcct cagctggatc
      601 cccgggtcct ggaagtctac agaggagtcc gggaggtgtt atgtaaatat cgcagtggga
      661 aactgcccaa ggcttttaag atcatccctg ccctgtccaa ctgggagcag atcctctatg
      721 tcacggagcc cgaggcctgg actgcagctg ccatgtatca agccaccagg atttttgcct
      781 ctaacctgaa ggagcgcatg gctcagcgct tctacaacct tgtcctgctt ccccgagtac
      841 gagatgacat tgctgaatac aaacgactca acttccacct ctacatggca ctcaagaagg
      901 ccctgttcaa acctggagcc tggttcaaag gaatcctgat cccgctgtgt gagtctggca
      961 cctgtaccct ccgagaagcc atcatcgtgg gcagcatcat cagcaagtgc tccatccctg
     1021 tgttgcactc cagtgcggcc atgctgaaga tcgcggagat ggagtacagt ggtgccagca
     1081 gcatcttcct gcgcctgctg ctcgataaga agtatgcact gccctaccgg gtgctcgacg
     1141 ctctggtctt ccattttctg gccttccgga cggagaagcg ccagctgccc gtgctttggc
     1201 accagtgcct actgacacta gcacagcgct acaaggctga cctggccacg gagcagaagg
     1261 aggccctcct agaactgctt cggctgcagc cccacccaca gctatccccg gaaatcaggc
     1321 gtgagcttca gagtgcagtc cccagagatg tggaagatgt tgttgtcacc atggaatgag
     1381 aacagtcacc tgtgttagtc caggggatgt gggaggaccc cagctggtgt agttaaagac
     1441 ctagtcagga cactgaaagg ttaccgtggc atctgtggct ccagtcttgg gcagggagga
     1501 ctgcatctgg ttggctttct cgccagtccc tgctcacttc tggaacctaa ctggagtcac
     1561 cccggttcag taccccacag cccacctggc acctggtatg agggccgctc tctccaggta
     1621 ctgtgtaagc tcactgggtt tcggataaac cagattcagt tatttattgg aaaaaaaaaa
     1681 aaaaaaaaaa aaaaaa
//
