LOCUS       NM_053556                805 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus BUD31 homolog (Bud31), mRNA.
ACCESSION   NM_053556
VERSION     NM_053556.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Bertram,K., Agafonov,D.E., Liu,W.T., Dybkov,O., Will,C.L.,
            Hartmuth,K., Urlaub,H., Kastner,B., Stark,H. and Luhrmann,R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   2  (bases 1 to 805)
  AUTHORS   Hsu,C.L., Liu,J.S., Wu,P.L., Guan,H.H., Chen,Y.L., Lin,A.C.,
            Ting,H.J., Pang,S.T., Yeh,S.D., Ma,W.L., Chen,C.J., Wu,W.G. and
            Chang,C.
  TITLE     Identification of a new androgen receptor (AR) co-regulator BUD31
            and related peptides to suppress wild-type and mutated AR-mediated
            prostate cancer growth via peptide screening and X-ray structure
            analysis
  JOURNAL   Mol Oncol 8 (8), 1575-1587 (2014)
   PUBMED   25091737
REFERENCE   3  (bases 1 to 805)
  AUTHORS   Chanarat,S. and Strasser,K.
  TITLE     Splicing and beyond: the many faces of the Prp19 complex
  JOURNAL   Biochim Biophys Acta 1833 (10), 2126-2134 (2013)
   PUBMED   23742842
  REMARK    Review article
REFERENCE   4  (bases 1 to 805)
  AUTHORS   Lu,Y., Xu,B., Ju,C., Mo,X., Chen,S., Feng,Z., Wang,X. and Hu,W.
  TITLE     Identification and profiling of circulating antigens by screening
            with the sera from schistosomiasis japonica patients
  JOURNAL   Parasit Vectors 5, 115 (2012)
   PUBMED   22686541
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 805)
  AUTHORS   Mototani,H., Iida,A., Nakajima,M., Furuichi,T., Miyamoto,Y.,
            Tsunoda,T., Sudo,A., Kotani,A., Uchida,A., Ozaki,K., Tanaka,Y.,
            Nakamura,Y., Tanaka,T., Notoya,K. and Ikegawa,S.
  TITLE     A functional SNP in EDG2 increases susceptibility to knee
            osteoarthritis in Japanese
  JOURNAL   Hum Mol Genet 17 (12), 1790-1797 (2008)
   PUBMED   18325907
REFERENCE   6  (bases 1 to 805)
  AUTHORS   Sautin,Y.Y., Jorgensen,M., Petersen,B.E., Saulnier-Blache,J.S.,
            Crawford,J.M. and Svetlov,S.I.
  TITLE     Hepatic oval (stem) cell expression of endothelial differentiation
            gene receptors for lysophosphatidic acid in mouse chronic liver
            injury
  JOURNAL   J Hematother Stem Cell Res 11 (4), 643-649 (2002)
   PUBMED   12201952
  REMARK    Review article
REFERENCE   7  (bases 1 to 805)
  AUTHORS   Stankoff,B., Barron,S., Allard,J., Barbin,G., Noel,F., Aigrot,M.S.,
            Premont,J., Sokoloff,P., Zalc,B. and Lubetzki,C.
  TITLE     Oligodendroglial expression of Edg-2 receptor: developmental
            analysis and pharmacological responses to lysophosphatidic acid
  JOURNAL   Mol Cell Neurosci 20 (3), 415-428 (2002)
   PUBMED   12139919
REFERENCE   8  (bases 1 to 805)
  AUTHORS   Cervera,P., Tirard,M., Barron,S., Allard,J., Trottier,S.,
            Lacombe,J., Daumas-Duport,C. and Sokoloff,P.
  TITLE     Immunohistological localization of the myelinating cell-specific
            receptor LP(A1)
  JOURNAL   Glia 38 (2), 126-136 (2002)
   PUBMED   11948806
REFERENCE   9  (bases 1 to 805)
  AUTHORS   Allard,J., Barron,S., Trottier,S., Cervera,P., Daumas-Duport,C.,
            Leguern,E., Brice,A., Schwartz,J.C. and Sokoloff,P.
  TITLE     Edg-2 in myelin-forming cells: isoforms, genomic mapping, and
            exclusion in Charcot-Marie-Tooth disease
  JOURNAL   Glia 26 (2), 176-185 (1999)
   PUBMED   10384882
REFERENCE   10 (bases 1 to 805)
  AUTHORS   Allard,J., Barron,S., Diaz,J., Lubetzki,C., Zalc,B., Schwartz,J.C.
            and Sokoloff,P.
  TITLE     A rat G protein-coupled receptor selectively expressed in
            myelin-forming cells
  JOURNAL   Eur J Neurosci 10 (3), 1045-1053 (1998)
   PUBMED   9753172
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Nov 26, 2020 this sequence version replaced NM_053556.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF058791.1, BC058456.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115, SAMN16676808
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                JAXUCZ010000012.1  14583993-14584007   c
            16-152              JAXUCZ010000012.1  14583011-14583147   c
            153-272             JAXUCZ010000012.1  14581733-14581852   c
            273-395             JAXUCZ010000012.1  14579200-14579322   c
            396-562             JAXUCZ010000012.1  14578056-14578222   c
            563-805             JAXUCZ010000012.1  14576602-14576844   c
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p11"
     gene            1..805
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /note="BUD31 homolog"
                     /db_xref="GeneID:89819"
                     /db_xref="RGD:621103"
     exon            1..15
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /inference="alignment:Splign:2.1.0"
     exon            16..152
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /inference="alignment:Splign:2.1.0"
     exon            153..272
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..613
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /note="EDG-2; protein G10 homolog; protein EDG-2; maternal
                     G10 transcript"
                     /codon_start=1
                     /product="protein BUD31 homolog"
                     /protein_id="NP_446008.2"
                     /db_xref="GeneID:89819"
                     /db_xref="RGD:621103"
                     /translation="MPKVKRSRKAPPDGWELIEPTLDELDQKMREAETEPHEGKRKVE
                     SLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCC
                     LRCIQTRDTNFGTNCICRVPKSKLEVGRIIECTHCGCRGCSG"
     exon            273..395
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /inference="alignment:Splign:2.1.0"
     exon            396..562
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /inference="alignment:Splign:2.1.0"
     exon            563..805
                     /gene="Bud31"
                     /gene_synonym="Edg2; G10; LPA1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcttgagt ttccgatgag acacaagact gaagaggaaa actgatctcc cccaaagaca
       61 tagaataatt ggtaaatctg gacgagaaca caggctcata actgcgaaga gcaaggattt
      121 ttatattact cttataggaa agagaccgaa agatctttac aagctatctt gctaggagat
      181 gcccaaagtc aaaagaagcc ggaaagcacc tccagatggc tgggagctga tcgagccaac
      241 gttggatgaa ctagatcaaa agatgagaga agctgaaact gaaccccatg aggggaagag
      301 gaaggtggag tctctgtggc ccatcttcag gatccatcac cagaaaaccc gctacatctt
      361 cgacctcttt tacaagagga aagccataag cagagaactc tatgaatact gcattaaaga
      421 aggctatgca gacaaaaacc tgattgcgaa gtggaagaag cagggctatg agaatctatg
      481 ctgtctacgc tgcatccaga ctcgagacac caacttcggc accaactgca tttgccgggt
      541 tcccaagagc aagctggaag tgggtcgcat catcgagtgc acgcactgtg gctgccgggg
      601 ttgctctggt tgactgacgc ccctgactcc tctgcatctt ggactttgga ccttgggctc
      661 ctgcttattg ggccactgcc tcctgaagca actcttctca gagtggcact cagagaaaag
      721 acccagggga agcatgagct ctacaggtga cagctttagt gttcaccagc tgagatctgt
      781 aaaaataaaa cctttagacc tctta
//
