LOCUS       NM_001047906            1364 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus BUB3 mitotic checkpoint protein (Bub3), mRNA.
ACCESSION   NM_001047906 XM_001053400 XM_001053470 XM_341943
VERSION     NM_001047906.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Li M, Li S, Yuan J, Wang ZB, Sun SC, Schatten H and Sun QY.
  TITLE     Bub3 is a spindle assembly checkpoint protein regulating chromosome
            segregation during mouse oocyte meiosis
  JOURNAL   PLoS One 4 (11), e7701 (2009)
   PUBMED   19888327
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  AUTHORS   Logarinho E, Resende T, Torres C and Bousbaa H.
  TITLE     The human spindle assembly checkpoint protein Bub3 is required for
            the establishment of efficient kinetochore-microtubule attachments
  JOURNAL   Mol Biol Cell 19 (4), 1798-1813 (2008)
   PUBMED   18199686
REFERENCE   3  (bases 1 to 1364)
  AUTHORS   Baker DJ, Jeganathan KB, Malureanu L, Perez-Terzic C, Terzic A and
            van Deursen JM.
  TITLE     Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient
            mice
  JOURNAL   J Cell Biol 172 (4), 529-540 (2006)
   PUBMED   16476774
REFERENCE   4  (bases 1 to 1364)
  AUTHORS   Kalitsis P, Fowler KJ, Griffiths B, Earle E, Chow CW, Jamsen K and
            Choo KH.
  TITLE     Increased chromosome instability but not cancer predisposition in
            haploinsufficient Bub3 mice
  JOURNAL   Genes Chromosomes Cancer 44 (1), 29-36 (2005)
   PUBMED   15898111
REFERENCE   5  (bases 1 to 1364)
  AUTHORS   Taylor SS, Ha E and McKeon F.
  TITLE     The human homologue of Bub3 is required for kinetochore
            localization of Bub1 and a Mad3/Bub1-related protein kinase
  JOURNAL   J Cell Biol 142 (1), 1-11 (1998)
   PUBMED   9660858
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY575212.1 and BC099199.1.
            
            On Jan 1, 2009 this sequence version replaced NM_001047906.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099199.1, FQ225106.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                DY575212.1         1-26
            27-1364             BC099199.1         1-1338
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..1364
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /note="BUB3 mitotic checkpoint protein"
                     /db_xref="GeneID:361662"
                     /db_xref="RGD:1306654"
     exon            1..68
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1049
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /codon_start=1
                     /product="mitotic checkpoint protein BUB3"
                     /protein_id="NP_001041371.2"
                     /db_xref="GeneID:361662"
                     /db_xref="RGD:1306654"
                     /translation="MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDV
                     PANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCV
                     EYCPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSGDRLIVGTAGRRVL
                     VWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKK
                     YAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYP
                     TSIASLAFSNDGTTLAIASSYMYEMDDTEHPEDGIFIRQVTDAETKPKST"
     exon            69..263
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
     exon            264..333
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
     exon            334..485
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
     exon            486..644
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
     exon            645..822
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
     exon            823..1039
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1334
                     /gene="Bub3"
                     /gene_synonym="Aa2-050"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcgagtgct ctgaagcgaa gtggggcggt agtggccggt gcagaaacgt tgcctaggcg
       61 aacacgagat gaccggttcg aatgaattca agctgaacca gccacccgag gatggcatct
      121 cctcggttaa gttcagcccc aacacctccc agttcctcct ggtctcctcc tgggatacgt
      181 ccgtgcgcct ctacgatgtg cccgccaatt ccatgaggct caagtaccag cacactggtg
      241 ctgtcctgga ctgcgccttc tacgatccaa cacatgcctg gagtggagga ctagatcatc
      301 aactgaaaat gcatgatttg aatactgatc aagaaaatct tgttggaact catgatgccc
      361 ctatcagatg tgtcgaatac tgtccagaag tgaacgtgat ggttactgga agttgggatc
      421 agacagttaa actgtgggat cccagaactc cttgtaatgc tgggacgttc tctcagccgg
      481 aaaaggtcta caccctgtcg gtgtctgggg acaggctgat tgtgggcaca gcaggccgcc
      541 gagtactggt gtgggacctg aggaacatgg gctacgtgca gcagcgcagg gagtccagcc
      601 tgaagtacca gactcgctgt atccgagcct tcccgaacaa acagggttat gtgttgagct
      661 ccattgaagg ccgagtagct gtggaatact tggacccgag ccctgaggtt cagaagaaga
      721 agtacgcctt caagtgtcac aggctaaagg agaacaacat cgagcagatt tacccagtca
      781 acgccatctc ctttcacaat atccacaaca catttgccac aggaggctct gatggatttg
      841 taaatatttg ggacccattt aacaaaaagc gcctgtgcca gttccatcgc taccccacca
      901 gcatcgcatc ccttgccttc agtaatgatg gaactacgct tgcaatcgca tcgtcatata
      961 tgtatgaaat ggatgatacc gagcatcctg aagatggtat cttcattcgc caagtgacag
     1021 atgcagagac aaagcccaag tccacgtaat catctggtga aagtggtttt tctggaaaag
     1081 ctttgtctgc ttcctataaa cacgtgcttc ttctccctaa ggcctgtttg tagctgttgg
     1141 acacttggtc tagtgtgtgg atttccgtgt ttcctgtcac aacagaaatg tctctgtctt
     1201 gtgattgggg tggggaggct ttgcccttgt acagtagttt gagagtctcc tgccccattg
     1261 ttgtttgtgt tcctatctaa aactgttata tttttctgct gtctaataaa tcagagattt
     1321 ggaactttta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
