LOCUS       NM_198134               1595 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus bone marrow stromal cell antigen 2 (Bst2), mRNA.
ACCESSION   NM_198134 XM_579725
VERSION     NM_198134.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Chen,C., Shi,H., Wang,B., Cao,N., Yu,C. and Zheng,L.
  TITLE     Aberrant expression of the innate restriction factor bone marrow
            stromal antigen-2 in primary Sjogren's syndrome
  JOURNAL   J Craniomaxillofac Surg 46 (11), 1899-1904 (2018)
   PUBMED   30249485
REFERENCE   2  (bases 1 to 1595)
  AUTHORS   Liberatore,R.A., Mastrocola,E.J., Powell,C. and Bieniasz,P.D.
  TITLE     Tetherin Inhibits Cell-Free Virus Dissemination and Retards Murine
            Leukemia Virus Pathogenesis
  JOURNAL   J Virol 91 (12), e02286-16 (2017)
   PUBMED   28381565
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1595)
  AUTHORS   Mukai,S., Oue,N., Oshima,T., Mukai,R., Tatsumoto,Y., Sakamoto,N.,
            Sentani,K., Tanabe,K., Egi,H., Hinoi,T., Ohdan,H. and Yasui,W.
  TITLE     Overexpression of Transmembrane Protein BST2 is Associated with
            Poor Survival of Patients with Esophageal, Gastric, or Colorectal
            Cancer
  JOURNAL   Ann Surg Oncol 24 (2), 594-602 (2017)
   PUBMED   26832883
REFERENCE   4  (bases 1 to 1595)
  AUTHORS   Kamada,A.J., Bianco,A.M., Zupin,L., Girardelli,M., Matte,M.C.,
            Medeiros,R.M., Almeida,S.E., Rocha,M.M., Segat,L., Chies,J.A.,
            Kuhn,L. and Crovella,S.
  TITLE     Protective Role of BST2 Polymorphisms in Mother-to-Child
            Transmission of HIV-1 and Adult AIDS Progression
  JOURNAL   J Acquir Immune Defic Syndr 72 (3), 237-241 (2016)
   PUBMED   26885809
REFERENCE   5  (bases 1 to 1595)
  AUTHORS   Hiramatsu,K., Serada,S., Kobiyama,K., Nakagawa,S., Morimoto,A.,
            Matsuzaki,S., Ueda,Y., Fujimoto,M., Yoshino,K., Ishii,K.J.,
            Enomoto,T., Kimura,T. and Naka,T.
  TITLE     CpG oligodeoxynucleotides potentiate the antitumor activity of
            anti-BST2 antibody
  JOURNAL   Cancer Sci 106 (10), 1474-1478 (2015)
   PUBMED   26498112
REFERENCE   6  (bases 1 to 1595)
  AUTHORS   Rollason,R., Korolchuk,V., Hamilton,C., Jepson,M. and Banting,G.
  TITLE     A CD317/tetherin-RICH2 complex plays a critical role in the
            organization of the subapical actin cytoskeleton in polarized
            epithelial cells
  JOURNAL   J Cell Biol 184 (5), 721-736 (2009)
   PUBMED   19273615
REFERENCE   7  (bases 1 to 1595)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   8  (bases 1 to 1595)
  AUTHORS   Jouvenet,N., Neil,S.J., Zhadina,M., Zang,T., Kratovac,Z., Lee,Y.,
            McNatt,M., Hatziioannou,T. and Bieniasz,P.D.
  TITLE     Broad-spectrum inhibition of retroviral and filoviral particle
            release by tetherin
  JOURNAL   J Virol 83 (4), 1837-1844 (2009)
   PUBMED   19036818
REFERENCE   9  (bases 1 to 1595)
  AUTHORS   Kupzig,S., Korolchuk,V., Rollason,R., Sugden,A., Wilde,A. and
            Banting,G.
  TITLE     Bst-2/HM1.24 is a raft-associated apical membrane protein with an
            unusual topology
  JOURNAL   Traffic 4 (10), 694-709 (2003)
   PUBMED   12956872
REFERENCE   10 (bases 1 to 1595)
  AUTHORS   Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
            Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
            and Sugano,S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On May 27, 2021 this sequence version replaced NM_198134.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ538349.1, SRR26643292.55656.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840111, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-310               JAXUCZ010000016.1  18254658-18254967   c
            311-386             JAXUCZ010000016.1  18253867-18253942   c
            387-426             JAXUCZ010000016.1  18253036-18253075   c
            427-547             JAXUCZ010000016.1  18251829-18251949   c
            548-1595            JAXUCZ010000016.1  18250593-18251640   c
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1595
                     /gene="Bst2"
                     /gene_synonym="DAMP-1; Damp1"
                     /note="bone marrow stromal cell antigen 2"
                     /db_xref="GeneID:378947"
                     /db_xref="RGD:727849"
     exon            1..310
                     /gene="Bst2"
                     /gene_synonym="DAMP-1; Damp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..529
                     /gene="Bst2"
                     /gene_synonym="DAMP-1; Damp1"
                     /note="BST-2; protein DAMP-1"
                     /codon_start=1
                     /product="bone marrow stromal antigen 2"
                     /protein_id="NP_937767.1"
                     /db_xref="GeneID:378947"
                     /db_xref="RGD:727849"
                     /translation="MAPSFYHYLPVAMDERWEPKGWSIRRWWLVAAILVVLIGVVLVC
                     LIVYFANAAHSEACKNGLRLQDECRNTTHLLKHQLTRAQDSLLQTEMQANSCNQTVMD
                     LRDSLKKKVSQTQEQQARIKELENKIERLNQELENLRTQKEISTTVQVNSGGSVVVSS
                     LLVLVAVLFLHF"
     exon            311..386
                     /gene="Bst2"
                     /gene_synonym="DAMP-1; Damp1"
                     /inference="alignment:Splign:2.1.0"
     exon            387..426
                     /gene="Bst2"
                     /gene_synonym="DAMP-1; Damp1"
                     /inference="alignment:Splign:2.1.0"
     exon            427..547
                     /gene="Bst2"
                     /gene_synonym="DAMP-1; Damp1"
                     /inference="alignment:Splign:2.1.0"
     exon            548..1595
                     /gene="Bst2"
                     /gene_synonym="DAMP-1; Damp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacataccac atggcaccct ctttctacca ctatctgccc gtggcgatgg acgagaggtg
       61 ggagccaaaa ggatggagca tccgccggtg gtggctggtg gccgcaatct tggtggtcct
      121 gatcggggtt gtcttagtct gcctgatagt ctacttcgcc aacgcagcgc acagcgaggc
      181 ctgtaagaac gggttgcggt tgcaggatga gtgccgaaac accacgcacc tgttgaagca
      241 ccagctcacc cgcgcccagg acagcctgct gcagacggag atgcaggcaa actcctgcaa
      301 ccagaccgtg atggaccttc gggattccct gaagaagaag gtgtctcaaa cccaggagca
      361 gcaggcccgc atcaaggaac ttgagaataa gatcgagagg ctgaaccagg agctggagaa
      421 tctgaggacc caaaaggaaa tttctaccac agtgcaggtg aactcaggcg gctccgtggt
      481 ggtctccagc ctactggtgc ttgtggcggt actgttcctg cacttttgag gacccaatag
      541 ttggcaggtc acagcctgtg tgaggtcatt gtgggtcgta gtggctctgg aggggtcctg
      601 gcaaccctaa ggatgtgaag accattaggt ggagcccaga ttgcatctcc tgctttgaac
      661 tggggagggg ggagggagtt ctgctttact gctttcatgg ttatcgggga ggggccgctt
      721 atttccgatg tctttggggg gcggggagcg ggggggcgga gccgggagtg ggggcgggaa
      781 ataaagtaat tcggaaagaa agtttgcttc taagttgcta gtgtcattag atccctggct
      841 tcctgccctg cttccccact gtcaggggcc accctaggag ttgaggtgga cacactgttg
      901 ctcatcacac ctgtccaccc atcctgtctg ctggaatcat catcaaggtc tgcagcagag
      961 ggcaaaaggc agccggtggt gactggctct tggttctgac tagtgtacta aggagaaagc
     1021 cgtctgagac cagaatgccg gtgctgcccc tctgcctccg gcagccagtc tgggctgggg
     1081 ttcctattag ggttctccag aggaaaagga gggcaggaaa gagggaggaa gggagagagg
     1141 gagagaggaa ggaaggaggg aggaagagaa gaggctcaca ggcctggtct gttgaagcct
     1201 gcttgctagc ttaaaatcac ccatagcttg gctgtgaccc ttgtttcatg cctgccaccc
     1261 attcgtattg ctaaacaaag acaaacaaag cctagcttga cttgagacat agaaaaacag
     1321 tttggctcac agcaaggtca agttgagcat atattcttgt tcttggacat ttcccaacca
     1381 tggccttcac tcaggacagc ttgagctgtt ctgtctaaac aactcaaaaa cccttggtgc
     1441 agccctcccc acgcatgctt atgagcccac tatggttttt tctttatata aactgatccc
     1501 caaaacacta ttggttgcag ctttctgctt acaaatttga gctatggccc tgatctgtca
     1561 gtcttgattc aataaatcag ccccattcaa ctggg
//
