LOCUS       NM_022261               2206 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus B-box and SPRY domain containing (Bspry), mRNA.
ACCESSION   NM_022261
VERSION     NM_022261.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2206)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   2  (bases 1 to 2206)
  AUTHORS   Birkenfeld,J., Kartmann,B., Anliker,B., Ono,K., Schlotcke,B.,
            Betz,H. and Roth,D.
  TITLE     Characterization of zetin 1/rBSPRY, a novel binding partner of
            14-3-3 proteins
  JOURNAL   Biochem Biophys Res Commun 302 (3), 526-533 (2003)
   PUBMED   12615066
  REMARK    GeneRIF: zetin 1/rBSPRY and 14-3-3 protein interactions have a role
            at specialized submembrane domains
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DN935023.1 and BC095901.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by NM_022261.3.
            
            On Aug 1, 2007 this sequence version replaced NM_022261.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166587.1, BC062051.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-349               DN935023.1         31-379
            350-2206            BC095901.1         1-1857
FEATURES             Location/Qualifiers
     source          1..2206
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q24"
     gene            1..2206
                     /gene="Bspry"
                     /note="B-box and SPRY domain containing"
                     /db_xref="GeneID:64027"
                     /db_xref="RGD:708400"
     exon            1..377
                     /gene="Bspry"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1385
                     /gene="Bspry"
                     /note="zetin-1"
                     /codon_start=1
                     /product="B box and SPRY domain-containing protein"
                     /protein_id="NP_071597.2"
                     /db_xref="GeneID:64027"
                     /db_xref="RGD:708400"
                     /translation="MSSDVSGTESGSESGPESVPEPVPEPGPEPESEPGPGPAPGPGP
                     GPAPGPGPGLGREPGQRYQPCQLCPEHGKPLSWFCLSERRPVCATCAGFGGRCHRHRI
                     RRAEEHAEELRNKIVDHCEKLQLQSAGITKYVAEVLQGKNQKAMIMANATREVIIQRL
                     SLVRCLCESEEQRLLEQVHSEEERAHQCILTQRAHWDDKLRKLDSLRTSMVDMLTHLN
                     DLQLIQMEQEILERAEEAEGILEPQESEKLSFNEKCAWSPLLTQLWATSVLGSLSGME
                     DVLIDERTVGPLLNLSEDRKTLTFNAKKSKVCSDDPERFDHWPNALAVNAFQTGLHAW
                     AVNVKHSCAYKVGVASAQLPRKGSGSDCRLGHNAFSWVFSRYDQEFCFSHNGNHEPLA
                     LLRCPTQLGLLLDLQAGELIFYEPASGTVLHIHRESFPHRLFPVFAVADQVISIVC"
     exon            378..476
                     /gene="Bspry"
                     /inference="alignment:Splign:2.1.0"
     exon            477..707
                     /gene="Bspry"
                     /inference="alignment:Splign:2.1.0"
     exon            708..733
                     /gene="Bspry"
                     /inference="alignment:Splign:2.1.0"
     exon            734..858
                     /gene="Bspry"
                     /inference="alignment:Splign:2.1.0"
     exon            859..2185
                     /gene="Bspry"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2143..2148
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bspry"
     regulatory      2163..2168
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bspry"
     polyA_site      2163
                     /gene="Bspry"
     polyA_site      2185
                     /gene="Bspry"
ORIGIN      
        1 cctgcgacag gtggagcgcg cggcctccgg caccggccat gtcctcggat gtctccggga
       61 cggagtccgg gtccgagtcc gggccggagt cggttccgga gccggtgccg gagcccgggc
      121 cggagccgga gtcggagccg gggccggggc cggcgcccgg gccggggccg gggccggcgc
      181 cggggccggg acccggactg gggcgggaac ccgggcagag gtaccagcca tgccagttgt
      241 gccccgagca cgggaagcct ctgagctggt tctgcctctc ggagcgacga ccggtatgcg
      301 ccacctgcgc cgggtttggc ggccgatgtc accggcaccg catccgccga gcggaggagc
      361 acgctgagga gctgagaaac aagattgtgg accactgtga gaagctgcag ttacagagtg
      421 ctggcatcac caagtatgtg gccgaggtcc tgcaggggaa gaaccagaaa gcaatgatca
      481 tggctaatgc aacgagggaa gtgatcatcc agaggttgag tctggtgagg tgcctgtgtg
      541 agagtgagga acagcgatta ctggagcagg tgcacagcga agaggagcgg gcccaccagt
      601 gcatcctgac tcagagggca cactgggatg acaaactccg gaaactggac tccctccgca
      661 ccagcatggt ggacatgctc acccatctga atgacctcca gctgattcag atggagcagg
      721 agattcttga gagggccgag gaagcagagg gcattttgga gccccaggag tcggagaaat
      781 taagctttaa tgagaagtgt gcttggagcc ctctactgac tcaactgtgg gcaacatcgg
      841 ttctcgggtc tctctcaggc atggaggatg tgcttattga tgaaaggact gtcggcccct
      901 tattgaattt gtccgaagat cgaaagaccc tgaccttcaa tgccaagaag tccaaggtct
      961 gctcagatga cccagagcgc tttgaccact ggcccaatgc cctggctgtc aatgccttcc
     1021 agactgggct ccatgcctgg gcagtgaatg ttaaacacag ctgtgcttac aaagtgggtg
     1081 tggcctcagc tcagctgccc cgaaagggtt ctggcagtga ctgccgcctg ggccacaatg
     1141 ccttctcctg ggtcttctcc cgctatgatc aagagttctg tttctcacac aacgggaacc
     1201 atgaacctct ggcgctcctc cggtgcccaa cacagctggg cctgctgttg gacctgcagg
     1261 caggagagct gatcttctac gagcctgcct cagggacagt gcttcacatc caccgtgagt
     1321 ccttcccgca caggctcttc ccagtctttg ctgtggccga ccaggtcatc tccatcgttt
     1381 gctgacctgt gaccaccgtg agaccagatc cacctcccca tcaccctttc gggtcaggcc
     1441 atgcttctag ctagtgtcct tttccttgat gatgtgactg gtgttcccca tgggcaactt
     1501 ttggagagat gggcatctgc ttcagactca gacataactt ttcaatgctg gtcatctgtg
     1561 gggatcctgt ttcttccctc ttggccttag tctcccacca cacttgtgcc cttccaaggg
     1621 tctcattaac ctgtgtctct ggcatccagc atagtacctt gtgcatggcg agtatacagc
     1681 aaggtacagt gagggaacaa atggttgatc aaacaggtga ccagttgtgt ggcagtgtct
     1741 ggaaaagcac cgcagtccct gaaagtgcct agctgcggag aaggctgtgc cgaactttcc
     1801 ctagcctctc agttcagtat ttcttggtct ttttcatgat acaccatgtg aagaggatgt
     1861 tttcctagca tacaaaggac aacctgccag gctactgttg gccagaacac tgtgccctcc
     1921 tcccacattc tgttgaggca ccagtatcct gtctccagga aacctgcttg cagcacactt
     1981 tttgacatct gtcccgggcc cagaggctga gctctagcat ggcttacatg tgtgagagaa
     2041 gggtgacaaa cattccccct ggtgaacacc ccacatcacg actcctcctt agggtggaga
     2101 gcagcaagca agaatagctg aggggaaagg agggctggcc ttaataaatg aatgtgagca
     2161 ttattaaagg gttctaaaga tgtaaaaaaa aaaaaaaaaa aaaaaa
//
