LOCUS       NM_019146              15951 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus bassoon (presynaptic cytomatrix protein) (Bsn),
            mRNA.
ACCESSION   NM_019146 XM_346835
VERSION     NM_019146.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 15951)
  AUTHORS   Terry-Lorenzo,R.T., Torres,V.I., Wagh,D., Galaz,J., Swanson,S.K.,
            Florens,L., Washburn,M.P., Waites,C.L., Gundelfinger,E.D.,
            Reimer,R.J. and Garner,C.C.
  TITLE     Trio, a Rho Family GEF, Interacts with the Presynaptic Active Zone
            Proteins Piccolo and Bassoon
  JOURNAL   PLoS One 11 (12), e0167535 (2016)
   PUBMED   27907191
  REMARK    GeneRIF: The findings provide a mechanism for the presynaptic
            targeting of Trio and support a model in which Piccolo and Bassoon
            play a role in regulating neurotransmission through interactions
            with proteins, including Trio, that modulate the dynamic assembly
            of F-actin during cycles of synaptic vesicle exo- and endocytosis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15951)
  AUTHORS   Gundelfinger,E.D., Reissner,C. and Garner,C.C.
  TITLE     Role of Bassoon and Piccolo in Assembly and Molecular Organization
            of the Active Zone
  JOURNAL   Front Synaptic Neurosci 7, 19 (2016)
   PUBMED   26793095
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 15951)
  AUTHORS   Korber,C., Horstmann,H., Venkataramani,V., Herrmannsdorfer,F.,
            Kremer,T., Kaiser,M., Schwenger,D.B., Ahmed,S., Dean,C.,
            Dresbach,T. and Kuner,T.
  TITLE     Modulation of Presynaptic Release Probability by the
            Vertebrate-Specific Protein Mover
  JOURNAL   Neuron 87 (3), 521-533 (2015)
   PUBMED   26212709
REFERENCE   4  (bases 1 to 15951)
  AUTHORS   Ivanova,D., Dirks,A., Montenegro-Venegas,C., Schone,C.,
            Altrock,W.D., Marini,C., Frischknecht,R., Schanze,D., Zenker,M.,
            Gundelfinger,E.D. and Fejtova,A.
  TITLE     Synaptic activity controls localization and function of CtBP1 via
            binding to Bassoon and Piccolo
  JOURNAL   EMBO J 34 (8), 1056-1077 (2015)
   PUBMED   25652077
  REMARK    GeneRIF: CtBP1 is targeted and/or anchored to presynapses by direct
            interaction with the active zone scaffolding proteins Bassoon and
            piccolo.
REFERENCE   5  (bases 1 to 15951)
  AUTHORS   Dresbach,T., Torres,V., Wittenmayer,N., Altrock,W.D., Zamorano,P.,
            Zuschratter,W., Nawrotzki,R., Ziv,N.E., Garner,C.C. and
            Gundelfinger,E.D.
  TITLE     Assembly of active zone precursor vesicles: obligatory trafficking
            of presynaptic cytomatrix proteins Bassoon and Piccolo via a
            trans-Golgi compartment
  JOURNAL   J Biol Chem 281 (9), 6038-6047 (2006)
   PUBMED   16373352
  REMARK    GeneRIF: Results suggest that a primordial cytomatrix assembles in
            a trans-Golgi compartment, and that transport via Golgi-derived
            vesicles is essential for delivery of cytomatrix proteins such as
            bassoon and piccolo to the synapse.
REFERENCE   6  (bases 1 to 15951)
  AUTHORS   Dick,O., Hack,I., Altrock,W.D., Garner,C.C., Gundelfinger,E.D. and
            Brandstatter,J.H.
  TITLE     Localization of the presynaptic cytomatrix protein Piccolo at
            ribbon and conventional synapses in the rat retina: comparison with
            Bassoon
  JOURNAL   J Comp Neurol 439 (2), 224-234 (2001)
   PUBMED   11596050
REFERENCE   7  (bases 1 to 15951)
  AUTHORS   Kneussel,M., Haverkamp,S., Fuhrmann,J.C., Wang,H., Wassle,H.,
            Olsen,R.W. and Betz,H.
  TITLE     The gamma-aminobutyric acid type A receptor (GABAAR)-associated
            protein GABARAP interacts with gephyrin but is not involved in
            receptor anchoring at the synapse
  JOURNAL   Proc Natl Acad Sci U S A 97 (15), 8594-8599 (2000)
   PUBMED   10900017
REFERENCE   8  (bases 1 to 15951)
  AUTHORS   Brandstatter,J.H., Fletcher,E.L., Garner,C.C., Gundelfinger,E.D.
            and Wassle,H.
  TITLE     Differential expression of the presynaptic cytomatrix protein
            bassoon among ribbon synapses in the mammalian retina
  JOURNAL   Eur J Neurosci 11 (10), 3683-3693 (1999)
   PUBMED   10564375
REFERENCE   9  (bases 1 to 15951)
  AUTHORS   Richter,K., Langnaese,K., Kreutz,M.R., Olias,G., Zhai,R.,
            Scheich,H., Garner,C.C. and Gundelfinger,E.D.
  TITLE     Presynaptic cytomatrix protein bassoon is localized at both
            excitatory and inhibitory synapses of rat brain
  JOURNAL   J Comp Neurol 408 (3), 437-448 (1999)
   PUBMED   10340516
REFERENCE   10 (bases 1 to 15951)
  AUTHORS   tom Dieck,S., Sanmarti-Vila,L., Langnaese,K., Richter,K.,
            Kindler,S., Soyke,A., Wex,H., Smalla,K.H., Kampf,U., Franzer,J.T.,
            Stumm,M., Garner,C.C. and Gundelfinger,E.D.
  TITLE     Bassoon, a novel zinc-finger CAG/glutamine-repeat protein
            selectively localized at the active zone of presynaptic nerve
            terminals
  JOURNAL   J Cell Biol 142 (2), 499-509 (1998)
   PUBMED   9679147
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Oct 27, 2007 this sequence version replaced NM_019146.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760389
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: PMID: 9679147, 16373352
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-316               JAXUCZ010000008.1  117754097-117754412 c
            317-725             JAXUCZ010000008.1  117703462-117703870 c
            726-1610            JAXUCZ010000008.1  117691570-117692454 c
            1611-2078           JAXUCZ010000008.1  117684463-117684930 c
            2079-8720           JAXUCZ010000008.1  117676982-117683623 c
            8721-10800          JAXUCZ010000008.1  117672821-117674900 c
            10801-11360         JAXUCZ010000008.1  117671969-117672528 c
            11361-11636         JAXUCZ010000008.1  117671693-117671968 c
            11637-11730         JAXUCZ010000008.1  117671466-117671559 c
            11731-11862         JAXUCZ010000008.1  117670605-117670736 c
            11863-11917         JAXUCZ010000008.1  117670334-117670388 c
            11918-12010         JAXUCZ010000008.1  117669844-117669936 c
            12011-15951         JAXUCZ010000008.1  117663447-117667387 c
FEATURES             Location/Qualifiers
     source          1..15951
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..15951
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /note="bassoon (presynaptic cytomatrix protein)"
                     /db_xref="GeneID:29138"
                     /db_xref="RGD:2223"
     exon            1..316
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..11903
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /note="zinc finger protein 231; neuronal double zinc
                     finger protein"
                     /codon_start=1
                     /product="protein bassoon"
                     /protein_id="NP_062019.2"
                     /db_xref="GeneID:29138"
                     /db_xref="RGD:2223"
                     /translation="MGNEASLEGGAGEGPLPPGGSGLGPGPGAGKPPSALAGGGQLPV
                     AGAARAAGPPTPGLGLVPGPGPGPGPGSVSRRLDPKEPLGSQRATSPTPKQASATAPG
                     RESPRETRAQGLSGQEAEGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAP
                     LPSSTLCPICKTSDLTSTSSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQ
                     MQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPEQERSRSPGATQSGPRQA
                     EAARATSVPGPTQATAPPEVGRVSPQPPLSTKPSTAEPRPPAGEAQGKSATTVPSGLG
                     AAEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPSPSKGPPKIVFSDASKEA
                     GPRPPGSGPGPGPTPGAKTEPGPRTGPGSGPGALAKTGGTPSPKHGRADHQAASKAAA
                     KPKTMPKERAACPLCQAELNVGSRGPANYNTCTACKLRVCTLCGFNPTPHLVEKTEWL
                     CLNCQTKRLLEGSLGEPAPLPLPTPQQPPAGVPQRAAGASPLKQKGPQGPGQPSGSLP
                     PKASPQAAKASPQAAKASPQAKPLRASEPSKTSSSAPEKKTGIPVKAEPVPKPPPETA
                     VPPGTPKAKSGVKRTDPATPVVKPVPEAPKSGEAEEPVPKPYSQDLSRSPQSLSDTGY
                     SSDGVSSSQSEITGVVQQEVEQLDSAGVTGPRPPSPSELHKVGSSMRPSLEAQAVAPS
                     GEWSKPPSGSAVEDQKRRPHSLSIMPEAFDSDEELGDILEEDDSLAWGRQREQQDTAE
                     SSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARADMTDEEFMRRQILEMSAEEDNLEED
                     DTAVSGRGLAKHGAQKASARPRPESSQESVALPKRRLPHNATTGYEELLSEEGPAEPT
                     DGALQGGLRRFKTIELNSTGSYGHELDLGQGSDPNLDREPELEMESLTGSPEDRSRGE
                     HSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPT
                     IEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPP
                     SNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAETLDGGPTRLYKSGSE
                     YNLPAFMSLCSPTETPSGSSTTPSSGRPLKSAEEAYEDMMRKAELLQRQQGQAAGARG
                     PHGGPSQPTGPRSQGSFEYQDTQDHDYGGRASQPAADGTPAGLGATVYEEILQTSQSI
                     ARMRQASSRDLAFTEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFPT
                     STSSDSSGGRVIPDVRVTQHFAKEPQEPLKLHSSPASPSLASKEVGMTFSQGPGTPAT
                     TAMAPCPASLPRGYMTPAGPERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPAG
                     SGRASREKPLSGGDGEVGPPQPSRGYSYFTGSSPPLSPSTPSESPTFSPSKLGPRATA
                     EFSTQTPSLTPSSDIPRSPGTPSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLA
                     SDASSQTRMVHASASTSPLCSPTDSQPASHSYSQTTPPSASQMPSEPAGPPGFPRAPS
                     AGVDGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRPPGTAVVDLRTAVKPTPII
                     LTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHTFLATATTVSI
                     TMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVKQVEQAVQTAPYRGGPRG
                     RPREAKFARYNLPNQVTPLARRDILITQMGTAQSVSLKPGPVPEPGAEPHRATPAELR
                     AHALPGTRKPHTVVVQMGEGAAGTVTTLLPEEPAGALDLTGMRPESRLACCDMAYKFP
                     FGSSCTGTFHPAPSAPDKSVTDAALPGQSSGPFYSPRDPEPPEPLTFRAQGVVGPGPH
                     EEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAVDLSSLKHSYS
                     LGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPMRRYSSVSNIYSDHRYGPRGDAVGF
                     QEASLAQYSATTAREISRMCAALNSMDQYGGRHGGGSGGPDLVPYQPQHGPGLNAPQG
                     LASLRSGLLGNPTYPEGQPSPGNLAQYGPAASQGTAVRQLLPSTATVRAADGMIYSTI
                     NTPIAATLPITTQPASVLRPMVRGGMYRPYGSGGVTAVPLTSLTRVPMIAPRVPLGPA
                     GLYRYPAPSRFPIASTIPPAEGPVYLGKPAAAKASGAGGPPRPELPAGGAREEPLSTT
                     APPAVIKEAPVAQAPAPPPGQKPAGDAAAGSGSGVLGRPVMEKEEASQEDRQRKQQEQ
                     LLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQ
                     QQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPATCEAPSRG
                     PPPAATELAQNGQYWPPLTHTAFIAVAGTEGPGQAREPVLHRGLPSSASDMSLQTEEQ
                     WEAGRSGIKKRHSMPRLRDACEPESGPDPSTVRRIADSSVQTDDEEGEGRYLLTRRRR
                     TRRSADCSVQTDDEDNAEWEQPVRRRRSRLSRHSDSGSDSKHEASASSSAAAAAARAM
                     SSVGIQTISDCSVQTEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQ
                     TEPDGQAQGVAGPQLIGPTAISPYLPGIQIVTPGALGRFEKKKPDPLEIGYQAHLPPE
                     SLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKQFIADSTLR
                     QQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPPNGLVRKV
                     KRTLPSPPPEEAHLPLAGQVPSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLV
                     EHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRVGRDYPPLRGLGEHR
                     DYLSDSELNQLRLQGCTTPAGQYVDYPASAAVPATPSGPTAFQQPRFPPAATQYTAGS
                     SGPTQNGFLAHQAPTYTGPSTYPAPTYPPGTSYPAEPGLPSQPAFHPTGHYAAPTPMP
                     TTQSAPFPVQADSHAAHQKPRQTSLADLEQKVPTNYEVISSPAVTVSSTPSETGYSGP
                     AVSSSYEHGKAPEHPRGGDRSSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELT
                     KDSTPTASDSQRPEPLGPGGVSGRPGKDPGEPAVLEGPTLPCCYGRGEEESEEDSYDP
                     RGKSGHHRSMESNGRPASTHYYSDSDYRHGARADKYGPGPMGPKHPSKNLAPAAISSK
                     RSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPTVSSSLTSRSRKFQDEITYGLKK
                     NVYEQQRYYGVSSRDTAEEDDRMYGGSSRSRVASAYSGEKLSSHDFSSRSKGYERERE
                     TAERLQKAGPKPSSLSMAHGRARPPMRSQASEEESPVSPLGRPRPAGGALPPGDTCPQ
                     FCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPR
                     DARSDRFRHHGGHTVSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHTSAKEHRH
                     HGDHGRHSGRHAGEEPGRRAARPHARDMGRHETRPHPQASPAPAMQKKGQPGYPSSAD
                     YSQPSRAPSAYHHASDSKKGSRQAHSGPTVLQPKPEAQAQPQMQGRQAVPGPQQSQPP
                     SSRQTPSGTASRQPQTQQQQQQQQQQQQQQQQQQQQGLGQQAPQQAPSQARLQQQSQP
                     TTRSTAPAASHPAGKPQPGPTTAPGPQPAGLPRAEQAGSSKPAAKAPQQGRAPQAQSA
                     PGPAGAKTGARPGGTPGAPAGQPAAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFS
                     SFW"
     exon            317..725
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            726..1610
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..2078
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            2079..8720
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            8721..10800
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            10801..11636
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            11637..11730
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            11731..11862
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            11863..11917
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            11918..12010
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
     exon            12011..15951
                     /gene="Bsn"
                     /gene_synonym="Znf231"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agatggcggc agctgcggtg gagcggagag tgtgagcgcc gcccgggagc cgccggcccg
       61 ggcgcagtgc gaccccgacc ccgcccgccc gcctgcccac catgggcaac gaggccagcc
      121 tggagggcgg cgcgggcgaa gggccgctgc cgccgggagg ctctggtctg ggtccgggcc
      181 ccggagcagg gaagccgcct tcagcactag ctggcggcgg acagctcccc gtggctggtg
      241 ctgcgcgagc ggcgggaccc ccgacccctg gtctcggtct ggtccccggc cctggtcccg
      301 gccccggccc gggcagtgtt tcccggagac tggaccccaa ggagcccctg ggcagccaga
      361 gagcaacttc tccaacccca aagcaagctt ctgctactgc tcctggccga gagagccccc
      421 gagagacaag ggcccaaggc ctgtcaggcc aggaggccga aggtccccgc aggacactgc
      481 aggtagacag caggacacag agatcaggac ggtccccctc cgtgtcacca gacagaggca
      541 gcactcccac atcaccctat tccgtccccc agattgcccc tcttcccagc agcaccctgt
      601 gtccaatatg caagacatcg gacctcacat caacctccag ccagccaaac ttcaacacct
      661 gcacccagtg tcacaacaag gtctgcaacc aatgtgggtt caaccccaac cctcacctca
      721 cccaggtgaa ggagtggctc tgtttgaact gtcagatgca gagggccctg ggaatggaca
      781 tgaccactgc acctcggtcc aagagccagc agcagctaca ctccccggcc ctgtctcctg
      841 cccactcccc agccaaacag cctctgggga agccagagca agagagatct cggagcccag
      901 gggccacaca gtctggtccc cgccaggctg aagcagccag ggccacctca gtgcctgggc
      961 ctacccaggc aactgcccct ccagaggtgg ggagggtgtc tcctcagccc cctctctcta
     1021 ccaagccttc cacagctgag cccaggccac ctgcaggaga ggcccagggc aaaagtgcca
     1081 ccacagtgcc ctccgggctt ggtgctgctg aacagaccca ggaggggctc accgggaagc
     1141 tctttggcct tggagcatca ctgctgaccc aggcaagcac ccttatgtct gtgcagccag
     1201 aggctgacac ccagggccag ccttccccca gcaaggggcc acccaagatt gtcttcagtg
     1261 atgccagcaa ggaggcgggt ccaagacccc caggctcagg gcccgggcct gggccaaccc
     1321 ctggagccaa aacggagcct gggcctagaa caggtcctgg atcagggcct ggggccctgg
     1381 caaaaactgg aggaaccccc agtccaaagc atggcagagc agaccatcag gcagcatcca
     1441 aagctgctgc caagccaaag accatgccga aggaaagggc tgcctgccca ctgtgccaag
     1501 ccgagctcaa cgtgggtagc aggggcccag ccaactacaa tacctgcact gcctgcaagc
     1561 tccgggtgtg caccctgtgt ggctttaacc cgacaccaca cctggtggag aaaacagagt
     1621 ggctctgtct gaactgccaa accaagaggc tgctggaggg cagcttgggg gagccggccc
     1681 ccctgcctct gcccacccca cagcagcctc cagcaggggt ccctcagcga gcagctggag
     1741 caagtcctct gaagcagaaa gggccacagg ggccgggcca gccctcaggc tccctgcctc
     1801 ccaaggccag tcctcaagcc gccaaggcca gccctcaggc cgccaaggcc agccctcagg
     1861 ccaagcctct cagggcttct gaacccagca agacctctag cagcgccccg gaaaagaaga
     1921 cagggatccc tgtgaaagct gagcctgtgc cgaagccacc tccagagact gctgtgcctc
     1981 ctgggactcc taaagcaaaa agcggggtga agaggaccga ccctgccacc ccagtcgtca
     2041 agcctgttcc agaagctccc aagagcgggg aggctgagga acctgtcccc aagccttact
     2101 ctcaggatct gtctcgaagc ccacaaagcc tcagtgatac aggctactcc tccgatggcg
     2161 tctccagctc ccagagtgag atcacaggtg ttgtacagca agaagtggag caacttgaca
     2221 gtgcgggggt gacaggccca cgtccaccca gcccctcaga gctccacaaa gtgggcagta
     2281 gtatgcgccc ttccctggag gcccaggctg tggctcccag tggtgagtgg agcaagccac
     2341 ccagcggcag tgctgttgaa gaccagaaac ggcgtcccca ctccctgtcc atcatgcccg
     2401 aggccttcga ctctgacgag gagctggggg atattctaga agaggatgac tccttggcat
     2461 gggggcgtca gagggagcag caagacacag ctgagtcttc agatgacttt ggcagccagc
     2521 tgaggcatga ctacgtggaa gacagcagtg aaggcggctt gtctcccctt ccacctcagc
     2581 ccccagccag ggcagatatg actgatgaag agttcatgcg gcggcagatc ctagaaatga
     2641 gcgccgagga agacaacttg gaggaagacg acaccgctgt ctccgggcga ggcctggcca
     2701 aacacggtgc ccagaaggca agtgccagac ccaggcccga atctagccaa gaatcagtag
     2761 cactgcccaa gaggcgcctg ccccataatg ccaccacagg ttacgaggaa cttctgtctg
     2821 aggaaggccc agcagagccc actgacggag cccttcaggg aggtctccga cgctttaaaa
     2881 ctattgagct caacagcaca ggtagctatg gtcacgagct agacctgggc caaggctctg
     2941 atcccaacct agaccgggag cctgagctgg agatggagag ccttacaggc tcgcctgaag
     3001 accgctctcg tggggagcac tcctctacac tgccggcttc cacgcctagc tatacatctg
     3061 gcacctcacc cacctccctg tcttccctgg aggaggacag tgacagcagc cccagccgca
     3121 ggcagcggct agaagaagcg aagcagcagc gcaaggcccg gcaccggtcc cacgggcccc
     3181 tgctgcccac cattgaggac tcttccgagg aggaggagct gcgggaagaa gaggagctgc
     3241 tgcgtgagca agagaagatg cgggaggtgg aacagcagcg aattcgaagc acagcccgca
     3301 agacccggcg tgacaaggaa gaacttcggg ctcagcggcg gcgtgagcgc tccaagacac
     3361 cgcctagtaa cctgtcaccc atcgaagatg cgtcccctac agaggagctg aggcaggcag
     3421 cggagatgga ggagctacac cgctcttcct gctctgagta ctccccctcc ccctccctgg
     3481 actcagaggc tgagaccctc gatggcggcc ccactcggct ctacaagtcg ggcagcgagt
     3541 acaacctgcc tgcctttatg tccctctgct caccaaccga gaccccttca ggcagttcca
     3601 ccacgcccag ttctggacgg ccccttaaga gtgcggagga ggcctacgag gacatgatga
     3661 gaaaagctga gctgctccag agacagcagg gccaggcggc aggggcccgg ggaccccatg
     3721 gcggcccctc tcagcccaca ggcccccgca gccagggctc ctttgaatac caagacaccc
     3781 aagaccatga ctatggcggc agggcttctc agcctgcggc agatggcacg cccgcaggcc
     3841 tcggagcaac agtgtatgag gagatccttc agacatccca gagcatagcc cggatgcggc
     3901 aggcctcctc gcgggatctg gccttcactg aggacaaaaa gaaggagaag cagtttctga
     3961 atgcggagag tgcatacatg gacccaatga agcaaaatgg tggcccactt acccctggga
     4021 ctagccccac ccaacttgct gctcctgtgt catttcccac ttccacctcc tcagacagca
     4081 gcgggggccg agttattccc gatgtcagag tcactcagca ttttgcaaaa gagcctcagg
     4141 agcctctcaa gctacatagc tctcctgcct ctcccagtct ggcctctaag gaggtaggca
     4201 tgaccttctc ccagggtcct ggaactccag ccaccacagc catggcgcct tgtccagcca
     4261 gccttccacg ggggtatatg actccagccg gccctgagcg cagcccatca acatcttcca
     4321 caatacacag ctatggacag cccccaacca ctgctaacta tgggtctcag acggaggagc
     4381 tgcctcacgc tcccagtggc cctgctggaa gtgggcgggc ctccagagag aagcctctga
     4441 gtgggggtga tggtgaggtt ggtccccccc agccttctcg gggatattct tattttacgg
     4501 gctctagccc acctctctct ccatccaccc cctccgagag ccccaccttc tctccaagca
     4561 agctgggtcc aagggccaca gcagagttct ctacacagac gccaagccta acgccttcct
     4621 ctgacattcc acggagccct ggcacccctt cccccatggt agcccaaggc acgcagacgc
     4681 cacaccgacc tagcactcct cgcttggtgt ggcagcagtc ttcccaggag gctcctgtta
     4741 tggtcatcac gctagcttca gatgcttcta gccagacccg aatggtacac gccagtgcct
     4801 ctacttcccc tctgtgctcg cctacggact ctcagcctgc ctcccatagc tacagccaga
     4861 ccacaccccc aagtgcatct caaatgccct cagaaccagc tgggccacct ggtttcccac
     4921 gagcacccag tgctggtgta gacgggccat tggcgctgta tggctggggt gccctccctg
     4981 ctgaaaacat ctccttatgc cggatctcct ctgtccctgg aacatctaga gttgagccgg
     5041 gccccaggcc cccgggcacc gcagtggtcg accttcgcac ggctgtcaag cccacaccca
     5101 ttatccttac cgaccagggc atggatctga cctctcttgc tgtggaagca aggaagtatg
     5161 gccttgccct ggatccagtt ccaggccgcc agtcaaccgc cgtgcagcct ctagttatta
     5221 acctcaatgc ccaagagcag acccatacct tcctggccac tgccaccaca gtgagcatca
     5281 ccatggcctc atctgtgctc atggcgcagc aaaagcaacc agtggtatat ggagatcctt
     5341 tccagagccg cctcgacttt ggccagggtt caggtagccc tgtgtgcctg gcccaggtca
     5401 agcaagtaga gcaggctgtc cagacagccc cataccgagg tgggcccagg ggaagaccca
     5461 gggaggctaa gttcgccagg tataaccttc ccaaccaggt aacacctctg gccagaaggg
     5521 acattctgat cactcagatg ggcactgccc agagtgttag cctgaagcca ggaccagtgc
     5581 cagagcctgg tgctgaaccc caccgggcta ctcctgcaga gctccgggca catgctctac
     5641 caggtaccag gaagccacac acagtggtgg tgcagatggg agagggcgca gccggcacgg
     5701 tgactaccct gctcccagaa gagccagcag gagccctgga cctcactggg atgaggcccg
     5761 agagccgact ggcatgctgt gacatggcct ataagtttcc ctttggcagt agctgcactg
     5821 gtaccttcca tcctgcccct agtgcacctg acaagagtgt gacagatgct gccctgcctg
     5881 gccaaagcag tggccccttc tacagtccca gagaccctga gcctcctgag cccctcacct
     5941 tccgggcaca aggggtcgta ggacctgggc cccatgaaga acagaggccc tacccacagg
     6001 gcttgcccgg taggctctac tcctccatgt ctgacaccaa tttggctgaa gctggtctca
     6061 actaccacgc ccagaggatt gggcagctct tccagggccc tgggagggac tcagctgtgg
     6121 atctcagctc gctgaagcat tcttacagct taggcttcgc tgatggacgc tacttggggc
     6181 agggcttaca gtatggctcg ttcacggacc tgcgccaccc cacagacctt ttgtctcacc
     6241 cactgcccat gaggcgctac agctctgtgt caaacatcta ttcggatcac cggtacggcc
     6301 cacggggaga tgccgtcggc tttcaggagg ccagcctggc ccagtacagt gccaccacag
     6361 cccgcgagat cagccgcatg tgtgccgccc tcaactccat ggaccagtac ggtgggcggc
     6421 atggcggtgg aagtggtggg cccgaccttg tgccgtatca gccccagcac gggcctggac
     6481 tcaatgctcc acagggtctg gcttccctta gatctggcct cctcggcaac cccacctacc
     6541 cagaagggca accaagtcct gggaaccttg ctcagtacgg gcctgcagca agccaaggaa
     6601 cagcagtcag acagttgctc ccatccacag caacagtgcg tgcagccgat ggcatgatct
     6661 actcgactat caatacccca atcgctgcaa cactgcccat caccacccag cctgcctcag
     6721 tactgcggcc catggtgcgt ggtggcatgt acaggcctta cggatctggc ggagtcacag
     6781 ctgtgcccct taccagcctg acccgggtgc ccatgattgc ccctcgggta cctcttggac
     6841 cagcagggtt ataccgctat cctgcaccaa gtcgattccc catcgcttcc accattccac
     6901 ccgctgaagg acctgtctat ttgggaaagc cagcagccgc caaggcctcg ggggcaggag
     6961 gcccgccaag gcctgagcta ccagcagggg gtgctcgaga agaacctctc tccacaactg
     7021 cccctcctgc tgtcatcaag gaagccccgg tggcccaggc cccggcccca ccaccaggcc
     7081 aaaagccagc aggagatgct gctgctggga gtggcagtgg agtcctcggc cggcctgtga
     7141 tggagaagga ggaggcatct caggaggacc ggcagcgaaa gcaacaggag cagctgctgc
     7201 agctggagcg ggaacgggta gagttggaaa agctccggca gttgcggcta caggaggagc
     7261 tggagcgaga gagggtggag ctgcagaggc atcgtgagga ggagcagctg ctggtgcaga
     7321 gagagttgca ggagctccag accatcaagc accatgttct gcagcagcag caagaagagc
     7381 gccaagctca gttcgcactg cagcgcgagc agctggcaca gcagcggctg cagctagagc
     7441 agatccagca actgcagcag cagctgcagc agcagctaga ggagcagaaa cagaggcaaa
     7501 aggccccctt tcctgcaacc tgtgaggcgc ctagccgagg gcctcccccc gctgctaccg
     7561 agctggccca gaacggccag tattggccac cattgaccca cacagccttc atcgccgtgg
     7621 caggaaccga agggcctggg caagctcgtg agcccgtgct gcacaggggc ctccccagct
     7681 ctgcctcaga catgtccctg caaactgagg agcagtggga ggcaggccgt agtggcatca
     7741 agaaacgtca ctctatgcca cgcctgagag acgcctgtga accagagtca ggccctgatc
     7801 ccagcacggt caggaggatt gcagacagca gtgttcagac agatgatgag gagggcgagg
     7861 gccgctacct cctgacccgt aggcgcagga cacggcgcag tgccgactgc agtgtgcaga
     7921 cagatgacga ggacaatgcc gaatgggagc agcctgtccg ccgccgcagg tctcgtcttt
     7981 cccgtcactc agactcaggc tctgacagca agcacgaggc ctcggcctca tcgtccgctg
     8041 ctgccgctgc ggcgagggcc atgagcagtg tgggtatcca gaccatcagt gactgctctg
     8101 tacagacaga gcctgagcag ctgcccaggg tctcaccagc catccacatc acagccgcca
     8161 ctgacccaaa ggtggagatc gtcagataca tatcagcacc agaaaagact gggcgagggg
     8221 agagcctggc ctgccagaca gaacccgatg ggcaggctca gggtgtggct gggccacagc
     8281 tcataggacc aactgccatc agcccctacc tacctggcat ccagatagtc accccaggag
     8341 ccctaggcag atttgaaaag aagaagccag atcctctgga gattgggtac caggcccacc
     8401 tgcccccgga gtccctgtcg cagcttgtga gccgccagcc tcccaagtct ccacaagtgc
     8461 tctactcacc agtgtcgcca ctgtccccac accggctcct ggacacctcg tttgcttcca
     8521 gtgagaggct gaacaaggct catgtgagtc cccagaagca gttcatagct gacagcactc
     8581 ttcgccagca gactctgccg cgccccatga agaccctgca gcggtccctg tccgacccta
     8641 agcccctgag ccccaccgcc gaggagtctg ccaaagagag attctccctc taccagcacc
     8701 aggggggact aggtagccag gtgtcggcgc tgccacccaa cggcctggtc cgcaaggtga
     8761 agcggacact gcccagcccc cctccagagg aagctcacct tcccctggct ggccaggtgc
     8821 cctcacagct gtatgcagcc agtctgctgc agcgagggtt ggcggggccc accaccgtcc
     8881 ctgctaccaa ggccagcctg ctccgggagc tggaccggga cctgcggctg gtggagcatg
     8941 aatccaccaa gctgcgcaag aagcaggcgg agttggacga ggaggagaag gagattgatg
     9001 ccaagctcaa gtacctggag ctgggcatca cccagcgcaa agagtctttg gccaaagacc
     9061 gggttggccg tgactaccca cctttacgtg gccttggtga gcatcgtgac tacctgtctg
     9121 acagcgagct caaccagctg cggctccagg gttgtaccac gcccgctggc cagtatgtgg
     9181 actaccctgc ctcagctgct gtgcctgcca ccccctctgg ccccactgcc ttccaacagc
     9241 cccggttccc acctgcagcc acacagtaca ctgcaggcag tagtggacca actcagaatg
     9301 gatttctagc ccaccaggca cctacctaca ctggccctag cacgtaccca gcacctacct
     9361 accctcctgg aacgagttat ccagctgagc ctggcctgcc aagccaaccg gctttccacc
     9421 ccacaggcca ttacgcagcc ccaacgccca tgccaaccac gcagagcgcc ccttttccag
     9481 tccaagctga cagtcacgct gcccaccaga agccgcgcca gacctcactg gctgatttgg
     9541 agcagaaggt tcccaccaat tatgaagtga tcagcagccc tgctgtaacc gtgtcctcaa
     9601 ccccctctga gaccggctac agtggtccag ctgtgagcag cagctacgag cacggtaaag
     9661 cccctgagca tccccggggt ggtgatcgaa gcagtgtgag ccagagccca gcccctacat
     9721 atccctctga ctcccattac accagtctgg agcagaacgt tccccgaaac tatgtgatga
     9781 tcgatgacat cagtgagcta accaaggaca gcacccccac tgcctcggat agccaacggc
     9841 cagagccctt gggcccaggt ggagtcagtg ggcgtcccgg gaaggatccc ggagaaccag
     9901 ctgtcctaga gggacccact ctgccctgct gctatggcag aggtgaggaa gaatctgagg
     9961 aggactcata tgacccccgt ggcaaatctg gtcatcaccg gagcatggag agcaacggcc
    10021 gaccagccag cacccactat tacagtgaca gtgactatag acatggggct cgagcagaca
    10081 agtatggccc aggacccatg gggccaaagc atccctctaa gaacctggcc ccggctgcca
    10141 tctcctccaa gcgcagcaag caccggaagc aaggcatgga gcaaaagatc tccaagttct
    10201 cacctatcga ggaggccaag gacgtggaat cagacctggc ctcctatccc ccacccaccg
    10261 tcagcagcag cctgacctct cggagcagaa agttccaaga cgaaatcacc tatgggctca
    10321 agaagaatgt gtatgaacag cagaggtact acggggtgtc cagccgggac acagccgagg
    10381 aggatgaccg catgtatggt ggtagcagcc ggtcccgagt ggcatcggca tacagtgggg
    10441 agaagctgtc cagccatgat ttcagcagcc gaagcaaagg gtatgaacgg gaacgggaga
    10501 ctgcagagcg acttcaaaag gcggggccca agccctcatc cctgagcatg gctcatggac
    10561 gggcacggcc ccccatgagg agccaggcct ctgaagagga gagccctgtc agccccttag
    10621 ggcggccccg tcccgcaggg ggcgctcttc ctcctgggga tacctgccca cagttctgct
    10681 ccagccactc catgccggac gtccaggagc acgtcaagga cggaccgcgc gcccacgcat
    10741 ataagcgtga ggagggctac atcttggatg actcccactg cgtggtttcg gacagtgaag
    10801 cgtatcacct gggccaggag gagacagact ggtttgataa gccccgagat gcccgctccg
    10861 accggttcag gcaccatggg gggcatacag tctcctcctc ccagaagcga ggccctgcca
    10921 ggcacagcta ccatgactac gatgagcccc ctgaggaggg cctgtggcct catgatgagg
    10981 gtggtccagg ccggcatacc tcagccaagg agcaccggca ccacggtgac cacgggaggc
    11041 actcaggccg ccatgctggt gaggagccag ggcgccgtgc tgccagacca catgctcggg
    11101 acatgggtcg ccacgagacc cggcctcacc ctcaggccag ccctgcccct gccatgcaaa
    11161 agaagggtca gcctgggtac cccagctctg ctgattactc acagccatcc cgggctccgt
    11221 cagcatacca ccatgcctct gacagcaaaa agggctcccg gcaggcccac tctgggccta
    11281 ctgtactgca gccaaagcca gaagcccagg cacagccaca gatgcaaggt cggcaggcgg
    11341 ttccgggacc gcagcaatca cagccaccat cgtccaggca gacgccctca ggcacagcat
    11401 cacgccagcc acagacacag cagcagcagc agcagcagca gcagcagcaa cagcaacagc
    11461 aacagcagca acagcaaggt cttgggcaac aagctcccca gcaggctcca tcacaggctc
    11521 ggctacagca acagagccag ccaaccaccc ggagcacagc ccctgctgcc agccacccag
    11581 cagggaaacc tcaaccaggc cccaccacag ccccagggcc ccagccagca ggactgccac
    11641 gtgcagagca ggcaggcagc tccaaaccgg cagccaaagc gccccagcag gggcgcgctc
    11701 ctcaggccca gtcagctcca ggacctgcag gggcgaagac tggagccagg cctgggggga
    11761 ccccaggggc tcctgctggt cagccagcgg cagaaggaga gagtgtattt tctaagatcc
    11821 tccctggtgg ggcagcagag caagccggaa agctgacaga agctgtctct gcttttggca
    11881 aaaaattttc ctcattctgg tgattgtgtc cagaagggct cctgaagacc tgaagaaaga
    11941 caatctcatt gctgtggaaa aatctctgga gtcagaggcc tgggtgcagc tctggactct
    12001 gcgtataacg catccacaac ctggcaaacc tttggcccaa agattcacac catgtgggcc
    12061 ccacccagca ggcaggcctc ggccgagcat gagaatgcaa tgttttctaa cagcagcgac
    12121 ctaggtgaag catctgcttg ctggaccaat gggaccattg gcttggggga acctttcatg
    12181 tctttcaaga gaccctgcct tactcaggcc agccgtcctt gggagagagg agccctcgcc
    12241 agaatgcggt tgctgctgag gctgtccgct gcttttcctg cagcctcctg tggcctgggc
    12301 agccaggctt ccaacgcgtt atacacagag tttgggtgca cactaccctc cctctaagac
    12361 accagaagtt ttttccacag ccttggagag gggctttgac tgagggctgg agccctaggc
    12421 tccgattcct tcacattcca gctggcccgg atccctctgt ggccatgagg ccttgcccgc
    12481 ttcaccctgc tctgtgggcg acaatggagc agacctccac atggccagca tgggtttggg
    12541 agaactttac aaacattagg acctaacact gtctcatcgc tgaaacaaga ggccatagca
    12601 ccgaaaagca gcgtgggcac cggctgaggc ttctcccagc ccatggatgg cagcgtaact
    12661 aagcatgcct gccatcctct taaagccatc cccccagcca ttgtgagcat cccagcaaca
    12721 ccgccattgt ctcgaccagc cggcccctcg gctcctcatc tgtacacctg gggatttctt
    12781 ttgatttcag gaacagcctt aatcattcca gtttgattta catgtatacc tcacaaactt
    12841 tttttttgtt ttattttttt ctttcccttt ctttgctttt atccctctgt ctcttcctcc
    12901 acctccaccc ccacctcgtg atggatggtt tggtttcctc tctgctctgc ccctgctcag
    12961 cacagggaga aatgttgatt tagaagcaat agcgggcagc cggccaccaa gagcacaaac
    13021 ccagggcgag gtctagggag gctcctccgc ccgcctgttt actgtgcaat tccagtcctc
    13081 ttaagccatc agcagtaggt gtgctcagag cagaggagcc aaggggaagg ttcagagccc
    13141 tgtgaggtaa aggggagtat gacaccgtcc attcacccgg gggactgggc tacacacctc
    13201 cccaaagccc ttccctcgga ggcctccctt catctcgggc ccagccacaa gtctcatctc
    13261 taatgttcta tgcaatgaaa tataaaccct caaagacaac tgttaatatt taataaattc
    13321 catgttacat ataaggagtt aattgcaaac acgcagttga gaaactggat agctctatct
    13381 gctcatacca ccgccccagc ctgatccttg tccccacttt ccgtgtgtgt acgtgtgaga
    13441 gcgaaaacga gagcatgtat gtacatgtgt gtgcgtgcgt gtatgtttgt gtgtgtgcgc
    13501 gggcgtgcgt gtgtaaattc taagtctgtg gcatgtttga cctgtggcag gactcgctgc
    13561 ttgccaggtg acccaccgcc tgtctcgcag tggagcatgc acagctcgaa gcttctttgc
    13621 acgatttcat tcattttaaa tgctcgacct cttgcttgga gttctttttg cctccaaacc
    13681 tctcccttaa gagcgcttct ccctgacttc gggacacgct agtgaagacc tcccagaact
    13741 gcctgaatat gccaggccat ggagcaggcc gtgcggcccc atacaccttg cagtttttaa
    13801 tctgtgtgcg acagcagatt aaaaacaaac aaaccaacca accttagaaa agacagagag
    13861 aggagcccgc acaggatgca tgcatatgaa cattctatgg gtctgctaca ggatctctac
    13921 ctgtgtatca tttttccctc ctatcctagg cctgagccaa aagaatctgg tcaccactcc
    13981 ccagttggac actgctcaag aacaaagctg gggtacatct gtggagaggc agcagccaag
    14041 ggatcctggc tgtgccctac aatccctaga tcttggccct gctctatgtc tctcctttgt
    14101 gatgtggagc ctcaaaggac tgtgatccaa gagatctgga atggagccag gggtcatagg
    14161 gtacccagga agagatggct gaaaatatca ttcggaaaat aacatccaca taagtaacag
    14221 cttcaagctg agctcaggtt tctcaggagc aaagcttacc gaagggtctg tgtaaccctc
    14281 tccacatctg ccccaggact tgcctcctcg gaaacctaag tattacactg ttgtcagtat
    14341 ctccctcact ggtccaggag tagagcagac agtacctgca tgacccctaa tgtctggcct
    14401 gcctccagag agttttggtg tacaccacgc atttctcagg ggttcacatg tctcatgctt
    14461 tttttttttt aacaaggctt ataactcctt tagagtggga ccctgtccac cgttggcagc
    14521 tgtggatggg acactgaaaa ctgtgttgga cttaagagcc tgaattccca ggatttagct
    14581 ttcttcccac tatgtaatat ctcagtatct caagtttgat ctcagagatc aaacttgggt
    14641 tatatggggc catctctata agggctgaag aaggccctca tcgaggaact cacaggccca
    14701 ggtgtgtgca ggatgtgccc agtgttcaga tccttgggat cgtggcagta tcccttccca
    14761 ctcatagtca ggactaggag atgagagcag gcagggatcc acaggtcaac ctctggcagc
    14821 acccctaggc tcaaaagtat taattttaca ccaaatttct tttctggcta aactccaagt
    14881 ttgacatttc tgatatctgc tactctaccc ctggctgtgc tcacaggaca gatatttgcc
    14941 cccttgtgat tatgacagca gactgcaata gtcttctagg tcataggtat cccgggctct
    15001 tgtgttgacc ctggggctcg gggatgagtg tttgctgctg tgggacatga taagcaatgg
    15061 gtgcatctcc aaatgggtaa gaagtctctg ggtagagtcc agatcttctc cattttcccc
    15121 tctcggtgtc ataagcaagg gtacccacct ctgcccaccc acggcctcaa cacactcacg
    15181 tcatagtgat ggtcctcgca ccatcctctt cctattcttt gggtagggtg aatggactca
    15241 gggctcacaa tgagagaaca gctagggcag ccattctggc ctgtattctg gagcctatgg
    15301 ggagttttct aggcaggtcc atgccataga gtgcagtcct gcccatagcc cttctccccc
    15361 catactgtaa ataatttgtc atcatggact ccaacagggt cggagggaca gatataacca
    15421 attgaaattc tctgaagatg ccatctgtct cccggggtgc cagcgcctgc tatcatgtgc
    15481 accaagtggc actggagagc catagaagtc ataagatact gtatgtgtaa gcacatgtac
    15541 atgaatgtgt gtgtgtgtgt atgtgtgtgt gtaagtgtgt gtgcgtgtgt gcacgagtct
    15601 cattcagcct ctggggtcaa atcagctcct ctcctctcct ctactcctgg agagtagtga
    15661 ccatcaacat tttccccttc tagcttctat gtcttgtttt tgctttccct cccccctcct
    15721 cccctctcct tccttctctc cttctttatt tgagggggaa gagtgctgta caaagtcaaa
    15781 caaacaagtt tacagttgta agtgcaatga cccgagtcct ccacatgacc ttgtgaattg
    15841 tgtgccgtcc tcctgtgctc tgtgagaact cgtggtactt cagtgtccct cccctgtact
    15901 gtgacaaggt atttctgtgg tatcagaata aaaggacttg atataaacaa c
//
