LOCUS       XM_017598835            3587 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus BRO1 domain and CAAX motif containing
            (Brox), transcript variant X1, mRNA.
ACCESSION   XM_017598835
VERSION     XM_017598835.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017598835.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017598835.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3587
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3587
                     /gene="Brox"
                     /gene_synonym="RGD1307161"
                     /note="BRO1 domain and CAAX motif containing; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 57 ESTs, 3 long SRA reads, 10 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 100 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:305031"
                     /db_xref="RGD:1307161"
     CDS             321..1556
                     /gene="Brox"
                     /gene_synonym="RGD1307161"
                     /codon_start=1
                     /product="BRO1 domain-containing protein BROX isoform X1"
                     /protein_id="XP_017454324.1"
                     /db_xref="GeneID:305031"
                     /db_xref="RGD:1307161"
                     /translation="MTHWFHRNPLKATAPVSFNYYGMITGPPASKICNDLRSARTRLL
                     ELFTDLSCNPETMKNAADLYFSLLQGFINSVGDSTQESKLRYIQNFKWTDTLQGHVPS
                     AQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKES
                     HIPKLLTPAEKGRDLEARLIDAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYETAS
                     FYQKADHTLSSLEPAHSAKWRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQE
                     AEKLYAEAEALCKEYGETKGPGPTAKPSGHLFFRKLGSLVKNTLDKCQRENGFIYFQK
                     IPTEAPQLELKANYGLVEPVPFEFPPMSALWTPEALAAFDLTKRPKDDSIKPKPEEEV
                     KPVKEPDIKPQKDTGCSVS"
ORIGIN      
        1 ttccctacca tcacccttgg atggtagtca gtggaagaat cgatggtgtt agcgtctaga
       61 tcggccgact ctcctagccc ggcgtcggct ttggttgctg ctagagggct tattacatgc
      121 ggaacagtgg cagtcatctg tttgtccttc cgaggttgac agggtcggag tgccacccta
      181 agacctgatc gcgatcctgg aggccggtcg tggggtcgcg gccggctgac ttagtaggag
      241 gacacaggga ggaagaggcc tgaccgtaaa caggaagtgg gcacgggcaa tatctagatg
      301 acagagcaca tcgcgtgaag atgacccact ggtttcatag gaacccatta aaagctacag
      361 ctcctgtgtc cttcaactac tatggcatga tcactgggcc tcctgcttca aagatttgca
      421 atgatttgag atccgccagg actcggctcc tcgaattgtt cactgatttg agctgtaatc
      481 cagaaacgat gaagaatgcc gcagacctgt atttctctct tttacaaggt ttcataaatt
      541 cagtgggtga ctccacccag gaaagcaaat tacgatacat tcagaatttc aaatggactg
      601 atacattaca aggacatgtt ccgagtgccc agcaggatgc tgttttcgaa ctgatttcca
      661 tgggatttaa tgtagcgctg tggtatacaa aatatgcttc aagattggct ggaaaagaaa
      721 acataacaga agatgaagca aaagaagttc accgaagcct aaaaattgca gctgggattt
      781 ttaaacattt aaaggaaagt catattccca aacttctgac accagcagaa aaggggcggg
      841 atttagaggc gcggctcatc gatgcgtaca tcatccagtg ccaggccgag gctcaggaag
      901 tgaccatcgc ccgagcaatc gagctgaagc acgctccggg gctgatcgcg gcactcgcgt
      961 acgaaacagc cagcttctat cagaaagcag atcatacttt gtccagtttg gagcctgcac
     1021 actctgctaa gtggagaaaa taccttcacc tgaagatgtg cttctacacg gcttatgcgt
     1081 actgctacca tggccagact ctgttggcga gcgataaatg tggagaagca atcagatctc
     1141 tccaagaagc agaaaaattg tacgcagagg cagaagccct gtgcaaagag tacggggaga
     1201 ccaaagggcc agggccaacg gccaagccat caggacactt gttctttcgg aagctcggaa
     1261 gccttgtgaa gaacaccctg gacaagtgtc agagggaaaa tggcttcatt tactttcaaa
     1321 aaattccaac agaagcccca caactggaac tgaaagcgaa ctatggcctg gtagagcctg
     1381 tgccttttga atttcctcct atgagtgctc tctggacacc agaagccttg gctgcatttg
     1441 atctcaccaa gagacccaag gatgacagta tcaaacccaa accggaagag gaagtgaaac
     1501 ctgtaaaaga accagatatc aaacctcaga aagacactgg gtgctccgtc tcataagaat
     1561 gccactcact tagaaatctc tgctggtcca taagagaaac ctcgggactt cagttcacct
     1621 ttttgattcc tctgaagccc attggatgat tgtcagcttt agagggactt ggcctttagt
     1681 ttatttattc ttggttttta acatagaggc atttcatgct tttgtttcgg gctctgcttt
     1741 acaatgagga catttggatg ggttggtttt tatgcctcta acgagcgtct atggggtggg
     1801 gggtggaact tttttgaact ctagatagta agtttcatgt taatgttttt ctactttcac
     1861 aaaaacgttt attcttcttg cttgatacca gaagaatgct ttgaaaagag atgagttcgc
     1921 ctctcctcac caacttgtca gatctgactc tagctcagtc ttctggtagg gaaactgaat
     1981 tgcagttaaa tcagaaaacc tcagaccaaa ttctttcctt atacttaacc agagtctata
     2041 attactagaa atcagtgtct tcaagaacgt gtaaggttct tggaaatcgg cagtatgggc
     2101 ctgtgcccct cagcctgctt cccagcttag tccgtgctgt tcctgccacc ctcagtactg
     2161 agacagtggt ttgttttggt ttttattagt accttttcta atggattttt tacttaaggg
     2221 gtaaagcttt gtactagcat ttagagtgct tctgtgtaga gagagaaaaa gaatggacgt
     2281 gtgttttaaa gaagtaaaat gttgcatgtt gtaaagaaag tctttgcaaa ctcaaccaag
     2341 acaggttgtc ctggatcgca ctggtaattt ctttgttaga agtgtttaag aaaatgcctt
     2401 tgttacctga tttgggtgta cattgtgttt ttaacatggt tttcttccat atgtatccta
     2461 tcagaattgt ttggcattag gccaaaggcc atagcaacag aaggttagga tatagacact
     2521 caaactatga tctttaaagt gggttgtatc acttaaagga cttggttata tccataaact
     2581 gggaatggtg gctgtgtgat acttcatcaa gtaacagatg tgggtgtatc ctacttggtt
     2641 actctcctgg gatgttaact tccttttcta ggtgacagat ttcttcacat aataggaata
     2701 ataatgtatg tgagaactta ctctgtgcca ggcagtgtgt aggcacatac acagaccact
     2761 gcatcccctt agcagccctg tgagaacaca tcggtctgca taaagcattg aaacaggaat
     2821 atgcatctcg tgatgaggaa tgatcgatta tacctatcaa ttaagataaa tcaataaatc
     2881 atataccata gtttatatgc ctttgaaaag ctacatataa tcactaaggg ttttttctta
     2941 ataagttaaa atgttagtta cagcctgcag tgtctaacat ttgaggctgc agctttcaga
     3001 acacttggag taactactga atgggcattg agctttcttt tgctgcctat aggaaaacag
     3061 taccttatta agttttaccc ttcctacagt cacttgttaa atggcagtta ctgacaaaac
     3121 tttaacaagt acttgctgct gcctgtctac gctctccctg cctaaaggac ctgttccatg
     3181 cactaatcct cattaaccta ggtagtctca gtgtggtttc tgtggactaa actgccattc
     3241 atgaaatggg aacacatact gtgtccggcg cttctgtaag gggcagtaaa tgctggtgtt
     3301 aaaacccata cttggcagtg ttcacatgat cgcatgagca gtcacagttg actgcagaag
     3361 taacaccaga agcctatccc gtaacgtgag gtttggaaga ggtaccggga gtctggggag
     3421 acaccaaaaa ggagcactgc acgaaggctg tggagagatg aaaccggaca ttgatgatgc
     3481 atgtatttca gaccaggcaa ggacagctca catgctactt ctgtacagtg tttatatgat
     3541 ttatcttttt atttatgata ataaatttta cttacatatt cactgga
//
