LOCUS       NM_001009605            1343 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus BRMS1, transcriptional repressor and anoikis
            regulator (Brms1), mRNA.
ACCESSION   NM_001009605 XM_238149
VERSION     NM_001009605.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Rivera,J., Megias,D. and Bravo,J.
  TITLE     Sorting nexin 6 interacts with breast cancer metastasis
            suppressor-1 and promotes transcriptional repression
  JOURNAL   J Cell Biochem 111 (6), 1464-1472 (2010)
   PUBMED   20830743
REFERENCE   2  (bases 1 to 1343)
  AUTHORS   Liu,Y., Smith,P.W. and Jones,D.R.
  TITLE     Breast cancer metastasis suppressor 1 functions as a corepressor by
            enhancing histone deacetylase 1-mediated deacetylation of RelA/p65
            and promoting apoptosis
  JOURNAL   Mol Cell Biol 26 (23), 8683-8696 (2006)
   PUBMED   17000776
REFERENCE   3  (bases 1 to 1343)
  AUTHORS   Stark,A.M., Tongers,K., Maass,N., Mehdorn,H.M. and Held-Feindt,J.
  TITLE     Reduced metastasis-suppressor gene mRNA-expression in breast cancer
            brain metastases
  JOURNAL   J Cancer Res Clin Oncol 131 (3), 191-198 (2005)
   PUBMED   15592684
REFERENCE   4  (bases 1 to 1343)
  AUTHORS   Samant,R.S., Debies,M.T., Shevde,L.A., Verderame,M.F. and
            Welch,D.R.
  TITLE     Identification and characterization of the murine ortholog (brms1)
            of breast-cancer metastasis suppressor 1 (BRMS1)
  JOURNAL   Int J Cancer 97 (1), 15-20 (2002)
   PUBMED   11774238
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088469.1.
            
            On Jan 13, 2005 this sequence version replaced XM_238149.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088469.1, SRR8487227.302596.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1343
                     /gene="Brms1"
                     /note="BRMS1, transcriptional repressor and anoikis
                     regulator"
                     /db_xref="GeneID:293668"
                     /db_xref="RGD:1311057"
     exon            1..62
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            63..208
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..810
                     /gene="Brms1"
                     /note="breast cancer metastasis suppressor 1"
                     /codon_start=1
                     /product="breast cancer metastasis-suppressor 1 homolog"
                     /protein_id="NP_001009605.1"
                     /db_xref="GeneID:293668"
                     /db_xref="RGD:1311057"
                     /translation="MPIQPSGKETEEMEAEGDSAAEMNGEADESEEERSGSQTESEEE
                     SSEMDDEDYERRRSECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYT
                     EPLGGLQQSLKIRIQVAGIYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLLGEL
                     QERIQRLEEDRQSLDISSEWWDDKLHSRGSSKTWDSVPPSKRKKAPLVSGPYIVYMLQ
                     EIDILEDWTAIKKARAAVSPQKRKADGP"
     exon            209..299
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            300..427
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            428..507
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            508..604
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            605..697
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            698..762
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            763..802
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
     exon            803..1261
                     /gene="Brms1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caacggcgga gcgttcacct gtgtccgaca gctctccggg accggaggcc ccagtctctg
       61 cgagcccaga tgcccatcca gccttcaggg aaagaaacag aagagatgga ggcagaaggc
      121 gattcagcag ctgagatgaa cggggaggca gatgagagtg aggaggaacg gagcggcagc
      181 cagactgagt cagaggagga gagctcagag atggatgacg aggactatga gcggcgccgc
      241 agtgagtgtg tcagtgagat gctggacctg gaaaagcagt tctcggagct gaaggagaag
      301 ttgttcaggg aacggctgag ccagctgcga ttacgactgg aggaagtggg ggccgagaga
      361 gccccagaat atacagagcc tcttggaggg ctacagcaga gcctaaagat tcgtattcag
      421 gtggcaggga tctacaaggg cttctgtctg gatgtgatca ggaataagta tgaatgtgaa
      481 ctacagggag ccaaacagca cctcgagagt gagaagctgc tgctgtatga cacactgctt
      541 ggggagctgc aggagcggat ccagaggctg gaggaggaca gacagagcct ggacatcagc
      601 tctgagtggt gggacgacaa actacatagc aggggcagtt cgaagacctg ggactcagtg
      661 ccacccagca agaggaagaa ggcaccactc gtttctggcc catacattgt gtacatgctg
      721 caggagatcg acatcctgga agactggacg gccatcaaaa aggccagggc agcagtgtcc
      781 cctcagaaga gaaaagcaga tggaccctga ccctgcattt acactcggag ggtccttggg
      841 gcagctggca ccgcacacag gattaacgtt tctctgcaaa ggcagggggt tacttactgc
      901 tggactcctc tgctctcctt gggatctgta taaccaaccg gccctgacgc tgacctggcc
      961 aagcaagacc gttgtctcca tccctgagca gcccacccct ccccaaagag taacttctca
     1021 gtgtccccca caagaagaca ggcctcatcc agagtcaaag cagcaaccct cctgactaaa
     1081 ccctggtcct tggccactga gtcatgagcc aggccccgct gcaggaggga ctcctgccag
     1141 agacatgttg ggtcttgccc atcctaactg ccactgggga gttggcttcc caggctttct
     1201 cagggccatt cctggtgtct gcctctcaga tcccaaggac tggaataaaa ttggacctgg
     1261 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1321 aaaaaaaaaa aaaaaaaaaa aaa
//
