LOCUS       NM_001009604             754 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus brain protein I3 (Bri3), transcript variant 1,
            mRNA.
ACCESSION   NM_001009604 XM_221925
VERSION     NM_001009604.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 754)
  AUTHORS   Yang,L., Xiong,Y., Hu,X.F. and Du,Y.H.
  TITLE     MicroRNA-323 regulates ischemia/reperfusion injury-induced neuronal
            cell death by targeting BRI3
  JOURNAL   Int J Clin Exp Pathol 8 (9), 10725-10733 (2015)
   PUBMED   26617783
  REMARK    GeneRIF: miR-323 might regulate ischemia/reperfusion-induced rat
            neuronal cell death via targeting BRI3.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 754)
  AUTHORS   Wickham,L., Benjannet,S., Marcinkiewicz,E., Chretien,M. and
            Seidah,N.G.
  TITLE     Beta-amyloid protein converting enzyme 1 and brain-specific type II
            membrane protein BRI3: binding partners processed by furin
  JOURNAL   J Neurochem 92 (1), 93-102 (2005)
   PUBMED   15606899
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Mar 16, 2021 this sequence version replaced NM_001009604.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ209378.1, BQ780004.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110, SAMN12840122
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               JAXUCZ010000012.1  15463116-15463365   c
            251-353             JAXUCZ010000012.1  15462730-15462832   c
            354-754             JAXUCZ010000012.1  15454673-15455073   c
FEATURES             Location/Qualifiers
     source          1..754
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p11"
     gene            1..754
                     /gene="Bri3"
                     /note="brain protein I3"
                     /db_xref="GeneID:304284"
                     /db_xref="RGD:1309187"
     exon            1..250
                     /gene="Bri3"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..486
                     /gene="Bri3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     membrane protein BRI3"
                     /codon_start=1
                     /product="membrane protein BRI3 isoform 1"
                     /protein_id="NP_001009604.1"
                     /db_xref="GeneID:304284"
                     /db_xref="RGD:1309187"
                     /translation="MDHKPLLQERPPAYNLEAGQGDYACGPHGYGAIPTAPPPPPYPY
                     LVTGIPTSHPRVYNIHSRAVTRYPANSIVVVGGCPVCRVGVLEYCFTCLGIFLAIVLF
                     PFGFLCCFALRKRRCPNCGAVFT"
     exon            251..353
                     /gene="Bri3"
                     /inference="alignment:Splign:2.1.0"
     exon            354..754
                     /gene="Bri3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggccgagctg cccgggacac cgccgtcgct gctaccgccg ccatccccgc cgggccgaag
       61 gaagcgagcc gggccggagc tggcgggcgc gcggccccgg gggccgcgat ggaccacaag
      121 cccctgttgc aggagcgccc gcccgcctac aacctggagg caggccaggg cgactacgcg
      181 tgcggcccgc acggctacgg ggccatcccc accgcgcccc cgccgccgcc ctacccctac
      241 ctcgtcacag ggatccccac cagccacccc cgggtctata acatccacag tcgagcggtc
      301 acccggtatc ctgccaactc catcgtcgtg gtcggaggct gcccggtctg cagggttggt
      361 gtcctggaat actgcttcac ctgcctgggc atcttcttgg ccatcgtcct gtttcctttc
      421 gggttcctct gctgcttcgc gctgaggaag cgaaggtgcc ccaactgtgg agcggtcttc
      481 acctaaaggg aaccacacac ccagttttcc tacgtcagct cttttctaat gtaaatgtcg
      541 tgtacaatag ttttatttga ttaagcttca ggactgtttt gtaaagtgcg tgctctgcct
      601 gcggtgggat ggactggctt agggctgcag agggggaagg cagcgacctg ctcccaaggc
      661 caaggataac gcgctgcttc tattttttgc agtcttcaat ttgagaatgg tgagaaatac
      721 tgttttaaat aaatgagatt cataccattg tgta
//
