LOCUS       NM_001024773            1869 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus BRF2 general transcription factor 3B subunit
            (Brf2), mRNA.
ACCESSION   NM_001024773 XM_224944
VERSION     NM_001024773.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1869)
  AUTHORS   Gouge,J., Satia,K., Guthertz,N., Widya,M., Thompson,A.J.,
            Cousin,P., Dergai,O., Hernandez,N. and Vannini,A.
  TITLE     Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2
  JOURNAL   Cell 163 (6), 1375-1387 (2015)
   PUBMED   26638071
REFERENCE   2  (bases 1 to 1869)
  AUTHORS   Vannini,A.
  TITLE     A structural perspective on RNA polymerase I and RNA polymerase III
            transcription machineries
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 258-264 (2013)
   PUBMED   23031840
  REMARK    Review article
REFERENCE   3  (bases 1 to 1869)
  AUTHORS   Dumay-Odelot,H., Durrieu-Gaillard,S., Da Silva,D., Roeder,R.G. and
            Teichmann,M.
  TITLE     Cell growth- and differentiation-dependent regulation of RNA
            polymerase III transcription
  JOURNAL   Cell Cycle 9 (18), 3687-3699 (2010)
   PUBMED   20890107
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097435.1.
            
            On Jun 10, 2005 this sequence version replaced XM_224944.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097435.1, EV779708.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1869
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.3"
     gene            1..1869
                     /gene="Brf2"
                     /note="BRF2 general transcription factor 3B subunit"
                     /db_xref="GeneID:306542"
                     /db_xref="RGD:1308817"
     exon            1..222
                     /gene="Brf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1319
                     /gene="Brf2"
                     /note="BRF-2; B-related factor 2; BRF2, subunit of RNA
                     polymerase III transcription initiation factor, BRF1-like;
                     BRF2, RNA polymerase III transcription initiation factor
                     50 subunit; BRF2, RNA polymerase III transcription
                     initiation factor subunit"
                     /codon_start=1
                     /product="transcription factor IIIB 50 kDa subunit"
                     /protein_id="NP_001019944.1"
                     /db_xref="GeneID:306542"
                     /db_xref="RGD:1308817"
                     /translation="MPNGSRCPDCGSSELVEDSHYSQSQLVCSDCGCVVTEGVLTTTF
                     SDEGNLREVTYSRSTGENEQVSRSQQRDLRRVRDLCRILKLPLTFEETAVSYYQKAYQ
                     LSGIRAARLQKKEVVVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLL
                     GLDVPSLCLADLVKSYCSSFKLFQASPSMPAKYVEDKDKMLSRTLLLVELANETWLVT
                     GRHPLPIITAATFLAWQSLRPSDRLTCSLARFCKLANVDLPYPAASRLQELLAVLLQM
                     ASQLAWLQVLRLDKRSVVKHIGDLLQHRHMLVRMAFQDGTAEVETKQQQPQGRGQQEE
                     VGDSTFDLPKRKRPASPALLLPPCMLKPPKRTHTMPPDSVVTGDEDISDSEIEQYLRT
                     PQEVRDFERAQAASRAAMSVPNPP"
     exon            223..282
                     /gene="Brf2"
                     /inference="alignment:Splign:2.1.0"
     exon            283..604
                     /gene="Brf2"
                     /inference="alignment:Splign:2.1.0"
     exon            605..1847
                     /gene="Brf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgctgacca gttataagtt cttaggagtg ggtgtctggc cgtactgcgg cactttacaa
       61 acggcgagat gccgaacgga agccgctgcc cagactgcgg ctcctctgag ctggtggaag
      121 attcgcatta ttcgcagagc cagctggtgt gctccgactg cggctgcgtg gtcaccgaag
      181 gggtccttac tactaccttc agcgacgagg gcaacctcag agaagtgacg tattctcgaa
      241 gcacagggga aaacgaacaa gttagccgca gccagcaacg agatctccgt cgagtaagag
      301 acctgtgtcg aattctgaag ttgccactaa cgttcgagga aaccgcagtc tcctactacc
      361 aaaaggcgta tcagctgtct ggcatccgcg ctgctaggct gcagaagaag gaagtggtag
      421 tcggatgctg tgttttaatc acctgtcggc aacataactg gcccctcacc atgggagcca
      481 tctgcactct gttgtatgca gatctggatg tgttttccag cacctacatg cagatagtga
      541 agcttctggg gctggacgtg ccgtccctgt gcctggcaga cttggtcaag tcttactgca
      601 gcagcttcaa actgttccaa gcatccccat ccatgccagc caaatacgtg gaggacaaag
      661 acaagatgct gtctcgaacc ttgctgttgg tggagctggc aaatgagacg tggctagtga
      721 ctggacggca tcccctgccg atcatcactg cagccacctt cctggcatgg cagtctctgc
      781 ggccttcaga ccggctgacc tgctctcttg cccggttttg taaattggca aatgtggacc
      841 tgccctaccc agctgcctcc cgcctgcagg agctcctggc cgtgctcctt cagatggcca
      901 gccagctggc ctggctacaa gtgctaagac ttgataagcg gtcggtggtg aaacacattg
      961 gtgaccttct ccagcaccgc catatgctgg tccgaatggc ttttcaggat ggaacagcag
     1021 aagtggagac caagcagcag cagccgcagg gacgaggaca gcaggaagag gtgggggaca
     1081 gtaccttcga tttgcccaag aggaaacgtc ccgccagtcc tgccctcctc ctcccaccct
     1141 gcatgttgaa gccccccaag cggacccata ccatgccccc tgattctgta gtgactggag
     1201 atgaggacat ttctgatagt gagattgagc aatatttgcg tacccctcag gaagttagag
     1261 actttgagag agcccaagct gctagccggg cagccatgag tgtccctaac ccgccatgat
     1321 gcccattctg gaaggtgtgt tcaattgtga ctgcaatctc taacaggcct gttgtgttgc
     1381 ataaagtgac ggtatgtgac ctttggatat ttctttaaag aaaccaagag tagcttgcag
     1441 tctgttaatg gacccaaggt cctagagaag gtgggaggca ggtgcggtgt ctgtggggga
     1501 cgtcctgacc tttggtgcag gtaaccaagg atccaaggat ggattcttcc taagaccgct
     1561 aaggaatctg tccagctctc ttctacccta gtgtgcagta aatgcattgg tgtgaacaag
     1621 ctggcatttg agcagtatcc accgttccat gacaggagca gttcctggcc atgcctggcc
     1681 taggctctag tggtttccag tattcataag ctcctttcca tcattaacaa aaggaccatg
     1741 ggtggacgac agctgtcgct cagagagttc tgcaagattt taatatatta aaacaaagag
     1801 gcatctgctg gaaaacattc tattgtataa aaccagagct tttaaaaaaa aaaaaaaaaa
     1861 aaaaaaaaa
//
