LOCUS       XM_039108630            3938 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus B-Raf proto-oncogene, serine/threonine
            kinase (Braf), transcript variant X1, mRNA.
ACCESSION   XM_039108630
VERSION     XM_039108630.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3938
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3938
                     /gene="Braf"
                     /note="B-Raf proto-oncogene, serine/threonine kinase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 2 ESTs, 10 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 7 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:114486"
                     /db_xref="RGD:619908"
     CDS             659..3202
                     /gene="Braf"
                     /codon_start=1
                     /product="serine/threonine-protein kinase B-raf isoform
                     X1"
                     /protein_id="XP_038964558.1"
                     /db_xref="GeneID:114486"
                     /db_xref="RGD:619908"
                     /translation="MAALSGGGGSSSGGGGGGGGGGGGGGGGGAEQGQALFNGDMEPE
                     AGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYT
                     SKLDALQQREQQLLESLGNGADFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQTPTDV
                     SRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQD
                     GYALEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQ
                     GFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPVPQEEAFSAETTLPSG
                     CSSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTI
                     EPVNIDEKFPEVELQDQRDLIRDQGFRGDGAPLNQLMRCLRKYQSRTPSPLLHSVPSE
                     IVFDFEPGPVFRGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSSSTEDR
                     SRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQ
                     QLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMI
                     KLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQ
                     FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIF
                     MVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIH
                     RSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGKELPGLSCLNSLL"
ORIGIN      
        1 tatattcact tcaacagatc aaacatagac aggatacgaa cagcatactg agaattcagc
       61 tgctctaaga catatttcta tgacatttgg cttggctgat gtttcaacct tggactttaa
      121 agtcttattt ttacgacacc cagagcttct ttgtaatggc agtaacaagt agtatagact
      181 tcccggcctt cttccctcta ggattttaac ttcttttaga acaccacccc tgctcttcta
      241 gtaaatccca catgacagaa caggctgggg acggaggaaa agtaggaagc cggcgccatg
      301 gaaactgtgc gggtagaaac ctgtgagcgc gagggtggtt ggaggagaag gaacactccc
      361 ctggagacag cggcgcgagg gtgctcctcg gatgacgtca cgcatccagg tgacgtcacg
      421 gccatgactt gcgggtgacg ccgttgccgc ggcgactcct cgtcgtctcc gcccccaccc
      481 ccccaagtcc cctcaggctc ggctgcgccg gggaccgctg gcgggttcca gaggtggcct
      541 ccgcccgggc cgctccgccc acgccccccg tgcctccgct cccgcctccg cccgccctgc
      601 gcctcccttc cccctccccg ccccgcggcg gccactcagc ccggctcgcg cttcgaagat
      661 ggcggcgctg agtggcggcg gtggcagcag cagcggtggc ggtggcggcg gcggcggcgg
      721 cggtggtggc ggcggcggcg gcggcgccga acagggacag gctctgttca atggcgacat
      781 ggagccggag gccggcgctg gcgccgcggc ctcttcggcc gcggacccgg ccattcctga
      841 agaggtgtgg aatatcaagc aaatgattaa gttgacacag gaacatatag aggccctatt
      901 ggacaagttt ggtggggagc ataacccacc gtcaatatac ctggaggcct atgaagagta
      961 caccagcaag ctagatgccc ttcagcagag agagcagcag ctgttggaat ccctgggtaa
     1021 tggagcagac ttttctgttt ctagctctgc atcaatggac accgttacat cttcctcctc
     1081 ttctagcctt tcagtgctac cgtcatctct ttcagttttt caaactccca cagatgtatc
     1141 acggaacaac cccaagtcac cacagaaacc tatcgttcgt gtcttcctgc ccaacaaaca
     1201 gaggacagtg gtgcccgcaa gatgtggtgt aacggtccga gacagtctaa agaaagcact
     1261 aatgatgagg ggtctcatcc cagagtgctg tgctgtttac agaattcagg acgggtatgc
     1321 tttagagaag aaaccaattg gctgggacac tgacatttcc tggcttactg gagaggagct
     1381 acatgttgaa gtactagaga atgttcctct gacaacccac aacttcgtac ggaaaacttt
     1441 tttcacctta gcattttgtg acttttgccg aaagctgctt ttccagggtt tccgctgtca
     1501 aacatgtggt tataagtttc accagcgttg tagtacagag gttccactga tgtgtgttaa
     1561 ttatgaccaa cttgatttgc tgtttgtctc caagttcttt gagcatcacc cagtaccaca
     1621 ggaggaggcc ttctcagcag agactaccct tccatctgga tgctcttccg cacccccctc
     1681 agactctatt gggccccaaa tcctcaccag tccatctcct tcaaaatcca ttccaattcc
     1741 acagcccttc cggccagcag atgaagatca tcgcaatcag tttgggcaac gagaccgctc
     1801 ctcctccgct cccaatgttc atataaacac aatcgaacct gtcaatattg atgaaaaatt
     1861 cccagaagtg gaattacagg atcaaaggga tttgattaga gaccaggggt ttcgtgggga
     1921 tggagcccct ttgaaccagc tgatgcgctg tcttcggaaa taccaatccc ggactcccag
     1981 ccccctcctc cattctgtcc ccagtgaaat agtgtttgat tttgagcctg gcccagtgtt
     2041 cagagggtca accacaggct tgtcggccac cccacctgcc tcattacctg gctcactcac
     2101 taacgtgaaa gccttacaga aatctccagg acctcagcgg gaaaggaagt cctcctcctc
     2161 ctcctcctcc acggaagaca gaagtcggat gaaaacactt ggtagaagag attcaagtga
     2221 tgattgggag attcctgatg gacagattac agtgggacag agaattggat ctgggtcctt
     2281 tggaactgtc tacaagggaa agtggcatgg cgacgtggca gtgaaaatgc tgaatgtgac
     2341 agcacccaca cctcagcagt tacaggcctt caaaaacgaa gtcggagtac tcaggaaaac
     2401 tcgacatgtg aacatcctcc ttttcatggg ctattctaca aagccacagc tggctattgt
     2461 tacacagtgg tgtgaaggct ccagcttata tcaccatctc cacatcattg agaccaaatt
     2521 tgagatgatc aaacttatag atattgcacg gcagactgca cagggcatgg attacttaca
     2581 cgccaagtca atcatccaca gagacctcaa gagtaataat atatttcttc atgaagacct
     2641 cacggtaaaa ataggtgact ttggtttagc cacagtgaag tcccgatgga gtgggtccca
     2701 tcagtttgaa cagttgtctg gatctatttt gtggatggca cccgaagtaa tcagaatgca
     2761 agataaaaac ccatatagct ttcagtcaga cgtgtatgca tttgggattg ttctgtatga
     2821 actgatgact ggtcagctac cttattcaaa catcaacaac agggatcaga taatttttat
     2881 ggtgggacga ggatacctat ctccagatct cagtaaggta cggagtaact gtccaaaagc
     2941 catgaagaga ttaatggcag agtgcctcaa aaagaaaaga gacgagagac cactctttcc
     3001 ccaaattctc gcctctattg agctgctggc ccgctcattg ccaaaaattc accgcagtgc
     3061 atcagaaccc tccttgaatc gggctggttt ccaaacagaa gattttagtc tgtatgcttg
     3121 tgcttctcca aaaacaccca tccaagcagg gggatatggt aaagaactac cgggattatc
     3181 ctgcttgaac tcactgttgt gactttaagt ggctctactg ccgtgagtga gaacccctct
     3241 gctggactgg ttgagtttgc tcacactcac acagatggga acacagccgc atggacatgt
     3301 ccctagtgct atagctagga ctctgccagt gagaaaggca gctgtccact tacttcagct
     3361 tctactgcta ctgtggtctc tgtggtaacc gaagaaaagg aagtagttat ctgtgttata
     3421 ggaaaacctg tcgtattaca gtatgaagcc tgccacaagt tggttgggga tacgtaatga
     3481 ctgacggaag cttacaatta ccacctagtc ccactctttc cttccttgtc cacagccgcc
     3541 tcagacagtc tctcaaacag aaccttatct tcctctagac cttggtaagt cattttgttc
     3601 ttaaacatac cttctataga ccttacttac tcagtacagc taaatcatct gtaatatgaa
     3661 aaggtttgga cccagactct tgtgtttgaa tgtatggccc atgaggagtt gcactattag
     3721 gaggtatggc cttgttagag gaaatgtgtc actgtggggt aggctctgag gtctccagtg
     3781 ctcaagctat gtccagaacg gcacacagtc tcctgctgcc ttcagatcaa gatgtagatc
     3841 cctcagctcc tcctccagca ccatgtctgc ctggaagccg tgcttcccac cttgataatg
     3901 gactgaacct ctgaaactgt aaaccagccc caattaca
//
