LOCUS       NM_199382               1576 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus bisphosphoglycerate mutase (Bpgm), mRNA.
ACCESSION   NM_199382 XM_216120
VERSION     NM_199382.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1576)
  AUTHORS   Lemarchandel,V., Joulin,V., Valentin,C., Rosa,R., Galacteros,F.,
            Rosa,J. and Cohen-Solal,M.
  TITLE     Compound heterozygosity in a complete erythrocyte
            bisphosphoglycerate mutase deficiency
  JOURNAL   Blood 80 (10), 2643-2649 (1992)
   PUBMED   1421379
REFERENCE   2  (bases 1 to 1576)
  AUTHORS   Rosa,R., Blouquit,Y., Calvin,M.C., Prome,D., Prome,J.C. and Rosa,J.
  TITLE     Isolation, characterization, and structure of a mutant 89
            Arg----Cys bisphosphoglycerate mutase. Implication of the active
            site in the mutation
  JOURNAL   J Biol Chem 264 (14), 7837-7843 (1989)
   PUBMED   2542247
REFERENCE   3  (bases 1 to 1576)
  AUTHORS   Pineda,M., Pinilla,M. and Luque,J.
  TITLE     Changes in enzyme activities involved in the degradation of
            1,3-bisphosphoglycerate during erythropoiesis in rat bone marrow
  JOURNAL   Cell Biochem Funct 2 (4), 254-256 (1984)
   PUBMED   6097373
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_199382.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062240.1, CB313858.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                JAXUCZ010000004.1  64107277-64107343
            68-728              JAXUCZ010000004.1  64119016-64119676
            729-1576            JAXUCZ010000004.1  64134902-64135749
FEATURES             Location/Qualifiers
     source          1..1576
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..1576
                     /gene="Bpgm"
                     /gene_synonym="Ab2-098"
                     /note="bisphosphoglycerate mutase"
                     /db_xref="GeneID:296973"
                     /db_xref="RGD:735018"
     exon            1..67
                     /gene="Bpgm"
                     /gene_synonym="Ab2-098"
                     /inference="alignment:Splign:2.1.0"
     exon            68..728
                     /gene="Bpgm"
                     /gene_synonym="Ab2-098"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..904
                     /gene="Bpgm"
                     /gene_synonym="Ab2-098"
                     /note="2,3-bisphosphoglycerate mutase"
                     /codon_start=1
                     /product="bisphosphoglycerate mutase"
                     /protein_id="NP_955414.1"
                     /db_xref="GeneID:296973"
                     /db_xref="RGD:735018"
                     /translation="MSKHRLIILRHGEGQWNKENRFCSWVDQKLNSDGLEEARNCGRQ
                     LKALNFEFDLVFTSILNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREK
                     MALNHGEEQVRLWRRSYNVTPPPIEESHPFFHEIYNDRRYKVCDVPLDQLPRSESLKD
                     VLERLLPYWKERISPEILKGKTVLISAHGNSSRALLKHLEGISDEDIINITLPTGVPI
                     LLELDENLRAIRPHQFLGNQEAIQAAIKKVDDQGKVRQNK"
     exon            729..1576
                     /gene="Bpgm"
                     /gene_synonym="Ab2-098"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatcctccc tggcacctgc agcacggcgt cgctgaggac tgggtgctac tggtggtttc
       61 cttgcagctg tactgctgtt ctcgaacctc acccaattga gaactccagg gcagcccagc
      121 caccagcatg tcgaagcaca gacttattat actaagacac ggagagggcc aatggaataa
      181 ggagaaccga ttctgtagtt gggtggacca gaaacttaac agtgacggac tggaggaggc
      241 tcggaactgt gggaggcagc tcaaagctct caacttcgag tttgatctcg tcttcacgtc
      301 catccttaac aggtccattc acacagcctg gctgatcctg gaagagctgg ggcaggagtg
      361 ggttcctgtg gagagctctt ggcgtctgaa tgagcgtcac tatggagcct tgattggtct
      421 caacagggag aaaatggctt tgaatcatgg tgaagagcag gtaaggctct ggaggagaag
      481 ctacaacgtg accccacctc ccattgagga gtctcatccc ttcttccatg agatctacaa
      541 tgaccggagg tacaaagtgt gcgacgtgcc cttggatcaa ctgccacgtt cagaaagctt
      601 gaaggatgtt ctggaaagac ttcttcccta ctggaaggaa aggatttctc cggaaatctt
      661 gaagggcaaa accgttctga tatctgctca tgggaatagc agtagagccc tcctgaaaca
      721 tctagaaggt atctcagacg aggatatcat caacatcact ctgcccactg gagttccgat
      781 tctgctggag ttggatgaga acctgcgtgc cattaggcct caccagttct tgggcaacca
      841 ggaggccatc caggcagcca ttaagaaagt ggatgatcaa gggaaagtga gacaaaacaa
      901 ataataaagt atgaccagga gcaagcagag tgcggggtgg tgtgtagtgt gttcccctgt
      961 gggcttctcc cctcctccca ctggctcact tcctccacgg ctgagtggta gagtttgtgt
     1021 agataactag gtagttgtca tggcccagac gtgacctttg gatgtctaag tctaacttaa
     1081 cttctgctcc tcccgtttga tttaacattg caaagtagta gccagcaggg tttgaccaag
     1141 gttgtttttt gttttagaga caggagagta acaggatgaa attgtttatc acttaacaag
     1201 tcatcactga gtccccactg gcagtcactg ttccaatgag caggtcactg ttttattcca
     1261 caatagttcc tgagaagagt gaacactact aggtagcact tgggcagttt acaccagagg
     1321 cccatcgaat ggcagagtca tggatgggcc cttgagaagg catccgagaa ccacagtagt
     1381 acaaggccct ttgatttccc ccagcccact gccatcctgt ttgccgtcag taaaatcaac
     1441 ttcagccagt gagaaggacc gggattggca cagccgtagc cgtttatgtt cttctgtttc
     1501 tctttgagct tttgaacttt aacctttggg gacttagcag ttagatgaaa ataaagcttt
     1561 gtgactacaa acagca
//
