LOCUS       NM_001013997            2109 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus bora, aurora kinase A activator (Bora), mRNA.
ACCESSION   NM_001013997 XM_224448
VERSION     NM_001013997.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2109)
  AUTHORS   Zhai,R., Yuan,Y.F., Zhao,Y., Liu,X.M., Zhen,Y.H., Yang,F.F.,
            Wang,L., Huang,C.Z., Cao,J. and Huo,L.J.
  TITLE     Bora regulates meiotic spindle assembly and cell cycle during mouse
            oocyte meiosis
  JOURNAL   Mol Reprod Dev 80 (6), 474-487 (2013)
   PUBMED   23610072
REFERENCE   2  (bases 1 to 2109)
  AUTHORS   Chan,E.H., Santamaria,A., Sillje,H.H. and Nigg,E.A.
  TITLE     Plk1 regulates mitotic Aurora A function through betaTrCP-dependent
            degradation of hBora
  JOURNAL   Chromosoma 117 (5), 457-469 (2008)
   PUBMED   18521620
REFERENCE   3  (bases 1 to 2109)
  AUTHORS   Macurek,L., Lindqvist,A., Lim,D., Lampson,M.A., Klompmaker,R.,
            Freire,R., Clouin,C., Taylor,S.S., Yaffe,M.B. and Medema,R.H.
  TITLE     Polo-like kinase-1 is activated by aurora A to promote checkpoint
            recovery
  JOURNAL   Nature 455 (7209), 119-123 (2008)
   PUBMED   18615013
REFERENCE   4  (bases 1 to 2109)
  AUTHORS   Hutterer,A., Berdnik,D., Wirtz-Peitz,F., Zigman,M., Schleiffer,A.
            and Knoblich,J.A.
  TITLE     Mitotic activation of the kinase Aurora-A requires its binding
            partner Bora
  JOURNAL   Dev Cell 11 (2), 147-157 (2006)
   PUBMED   16890155
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088204.1.
            
            On Apr 20, 2005 this sequence version replaced XM_224448.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088204.1, SRR8487230.141827.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132294, SAMD00132295
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2109
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q21"
     gene            1..2109
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /note="bora, aurora kinase A activator"
                     /db_xref="GeneID:306102"
                     /db_xref="RGD:1309522"
     exon            1..249
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            250..417
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     CDS             265..1869
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /codon_start=1
                     /product="protein aurora borealis"
                     /protein_id="NP_001014019.1"
                     /db_xref="GeneID:306102"
                     /db_xref="RGD:1309522"
                     /translation="MGDVSELKMQITPATPGRIPVLNPFESPSDYSNLHEQTLASPSV
                     FKSTKLPTPGEFRWSIDQLAVINPVEIDPEEIHRQASYLSLSRIDKDVEDKRQKAIEE
                     FFTKDVIVPSPWTDHDGKQPSELHPSKCLTSNGDSPVGKKPSLPSQKCNAACQTLLSL
                     PVDFNLEAVLGDYFRADDSVDQSPGNLSSSSLRRKLFLDVNGSISDSLPSASPRSPPN
                     SARGSLEGQFSSSPIQNNAKKYSLGSLTTSPSAICSPTFSPIALQVGKTPLSEHRKFT
                     FHSPEASSGGSSTGIANPSIRSPYIDGCSPIKNWSPRGLRGGPQYLSSLIRVPFALET
                     HSEDEEDNVSSTDVAALGTNAVAAPLQQLDCEPLACGDPFVVSAMPVTQSQSSTCEKD
                     LGLLGDFESERDHDTVDMVDPIDTADESTWIKEPVGNGNSPMAEFVSGIAFSIENSHM
                     CMSPLAESSVLPCESSNVQMDSGYNTQTCGSNITDIVGTESYCKENVTQSFEAQMKPQ
                     VNNIKQDHTVQRCWMKTTSPSQCSSL"
     exon            418..524
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            525..570
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            571..652
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            653..718
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            719..775
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            776..939
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1075
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1671
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1803
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..2084
                     /gene="Bora"
                     /gene_synonym="RGD1309522"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctgcggtg ggccctgcgg ggtgctagaa cttccacgtt acccacgaat gtcggtacgt
       61 cctccgtggc cccaggcctg gactcctgtc tcgagttgga ccgctctggt ttcctggctg
      121 cagacgtgcc tgtgcgctcg cctaggtgtg aaggggagca gagagaggga cgcctggaag
      181 ctgaatggtc gctggaagtg acgtccctgc tggtacggag ggagcccgct caactttggt
      241 cttccaaaat ttgcttcctg ggctatggga gatgtcagcg aattaaaaat gcaaataaca
      301 ccagcaactc caggaaggat ccctgtttta aatccctttg aaagtcccag tgattattct
      361 aatctccatg aacaaaccct tgctagtcct tctgtcttta agtccacaaa actaccaact
      421 ccaggggaat ttaggtggtc tattgatcag ctggctgtaa taaatcctgt agaaatagac
      481 ccagaggaga ttcatcgtca ggcttcctac ttaagtcttt ctcgaataga taaagatgtg
      541 gaagacaaaa gacaaaaggc cattgaagag ttttttacta aagatgtcat tgtgccctcg
      601 ccctggaccg atcatgatgg aaaacagcct tccgagcttc atcccagtaa atgcctaact
      661 agcaatggtg actctcctgt tgggaaaaag ccgagtctcc cttctcagaa atgcaatgct
      721 gcctgccaga ctctgttgtc tcttcctgtg gattttaatt tggaagccgt attaggagac
      781 tactttagag cggatgactc tgtggaccaa tctcccggga acctcagttc ttcgtctctc
      841 aggagaaagc tctttttaga cgtgaatggg agcatctccg actccttacc ttcagcttct
      901 cccagaagtc ctcccaacag tgcccgagga tctcttgagg gacagttttc ttccagcccc
      961 attcagaaca atgcaaaaaa gtacagtttg ggaagcttaa ccaccagccc atcggctatc
     1021 tgttcaccta cgttctcacc aattgcactt caagtaggaa agacaccact gtcagagcac
     1081 aggaagttta catttcattc tcctgaagct tcctctggag gaagttctac tgggattgct
     1141 aatccaagca tcaggagtcc atatatagat ggctgctcac caattaaaaa ttggtctcct
     1201 cggggactca gaggtggtcc tcagtatttg tcgtcactga ttcgggtacc ttttgctctt
     1261 gagactcaca gtgaagatga agaagacaac gtttcctcca cagatgtggc tgcactgggc
     1321 acaaatgctg tggcagcccc ccttcagcag ttggactgtg agcctttggc ttgtggcgac
     1381 cctttcgttg tcagtgccat gcctgtcact cagagtcagt ctagtacctg tgagaaagac
     1441 ctagggctgc tgggggactt tgaaagtgaa agggaccatg acaccgtgga tatggtcgat
     1501 ccgatagaca cagcggatga aagcacgtgg ataaaagagc ccgtgggtaa tgggaattca
     1561 cccatggctg agtttgtgag tggaattgcc ttcagcattg agaactccca catgtgcatg
     1621 tcacctcttg cagagagcag tgttctgccc tgtgaaagca gtaatgtcca gatggacagt
     1681 ggctataaca cacagacttg tggaagtaat atcactgata ttgttgggac agaaagctac
     1741 tgcaaagaaa atgtcacaca gtcctttgaa gcacaaatga aacctcaagt taataacata
     1801 aagcaagatc acactgtgca gaggtgttgg atgaaaacta caagtccatc tcagtgcagc
     1861 agcctgtagt ctcaagacca aagactgcca ctcaatagtc cctgacgtat ttatagggga
     1921 cttcgagtta atgtgatggt gatgggggta cctgcttcac ataatatgcc tagttccctc
     1981 cttaatgtga aaagctgcaa aggaaattat gacaggacca gatgctccaa gttgttaaag
     2041 tacacattta ttttttaaaa atcaataaat atttttatat ttgcaaaaaa aaaaaaaaaa
     2101 aaaaaaaaa
//
