LOCUS       NM_001100766            1301 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus biogenesis of lysosomal organelles complex 1
            subunit 4 (Bloc1s4), mRNA.
ACCESSION   NM_001100766 XM_001063389 XM_344255
VERSION     NM_001100766.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Lee,H.H., Nemecek,D., Schindler,C., Smith,W.J., Ghirlando,R.,
            Steven,A.C., Bonifacino,J.S. and Hurley,J.H.
  TITLE     Assembly and architecture of biogenesis of lysosome-related
            organelles complex-1 (BLOC-1)
  JOURNAL   J Biol Chem 287 (8), 5882-5890 (2012)
   PUBMED   22203680
REFERENCE   2  (bases 1 to 1301)
  AUTHORS   Larimore,J., Tornieri,K., Ryder,P.V., Gokhale,A., Zlatic,S.A.,
            Craige,B., Lee,J.D., Talbot,K., Pare,J.F., Smith,Y. and Faundez,V.
  TITLE     The schizophrenia susceptibility factor dysbindin and its
            associated complex sort cargoes from cell bodies to the synapse
  JOURNAL   Mol Biol Cell 22 (24), 4854-4867 (2011)
   PUBMED   21998198
REFERENCE   3  (bases 1 to 1301)
  AUTHORS   Ciciotte,S.L., Gwynn,B., Moriyama,K., Huizing,M., Gahl,W.A.,
            Bonifacino,J.S. and Peters,L.L.
  TITLE     Cappuccino, a mouse model of Hermansky-Pudlak syndrome, encodes a
            novel protein that is part of the pallidin-muted complex (BLOC-1)
  JOURNAL   Blood 101 (11), 4402-4407 (2003)
   PUBMED   12576321
REFERENCE   4  (bases 1 to 1301)
  AUTHORS   Gwynn,B., Ciciotte,S.L., Hunter,S.J., Washburn,L.L., Smith,R.S.,
            Andersen,S.G., Swank,R.T., Dell'Angelica,E.C., Bonifacino,J.S.,
            Eicher,E.M. and Peters,L.L.
  TITLE     Defects in the cappuccino (cno) gene on mouse chromosome 5 and
            human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent
            mechanism
  JOURNAL   Blood 96 (13), 4227-4235 (2000)
   PUBMED   11110696
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On or before Jun 1, 2008 this sequence version replaced
            XM_001063389.1, XM_344255.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC091265.1, FQ213984.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1301              JAXUCZ010000014.1  78267735-78269035
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1301
                     /gene="Bloc1s4"
                     /gene_synonym="Cno; RGD1306037"
                     /note="biogenesis of lysosomal organelles complex 1
                     subunit 4"
                     /db_xref="GeneID:364183"
                     /db_xref="RGD:1306037"
     exon            1..1301
                     /gene="Bloc1s4"
                     /gene_synonym="Cno; RGD1306037"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..672
                     /gene="Bloc1s4"
                     /gene_synonym="Cno; RGD1306037"
                     /note="biogenesis of lysosomal organelles complex-1,
                     subunit 4, cappuccino"
                     /codon_start=1
                     /product="biogenesis of lysosome-related organelles
                     complex 1 subunit 4"
                     /protein_id="NP_001094236.1"
                     /db_xref="GeneID:364183"
                     /db_xref="RGD:1306037"
                     /translation="MEEGPAIGTLSREVSTEEAEPLVAAWSGDSGHVSQSHSSASGPW
                     EDDGTEDAPGRDLPLLRRAALGYASSLLPATGPRPEVEALDASLEDLLAKVDEFVGML
                     DMIRGDSSHVVSEGVPRIHAKAAEMRRIYGRIDKLEAFVRMIGSSVARMEEQVTKAEA
                     ELGTFPRAFRRLLHTISVPALFKSAPTAPQRAVYEPPVLFRTEDHFPGSGDRPQL"
ORIGIN      
        1 gcaccggaag cggccaggcg ggccatggag gaaggacccg cgatcggaac cctgtctcga
       61 gaggtctcga ctgaggaggc cgagccgttg gtcgccgcgt ggagcgggga cagcggccac
      121 gtatcgcaga gccacagcag cgcgtccgga ccttgggaag atgacggcac cgaggacgcg
      181 ccaggccgcg acctgccgct gctgcgccgc gccgccttgg gctacgcctc cagcttgctg
      241 cctgccaccg ggccgcggcc ggaggtggag gcgctggacg ccagcctgga ggacctgctc
      301 gccaaggtgg acgagttcgt gggcatgctg gacatgattc gcggagactc gtctcatgtg
      361 gtgagcgagg gtgtgcctcg gatccacgct aaagccgccg agatgaggcg catctacggc
      421 agaatcgaca aactagaggc cttcgtgagg atgatcggta gtagcgtggc cagaatggag
      481 gagcaagtca ccaaggccga agccgaactg gggaccttcc cccgagcctt tcggaggctg
      541 ctgcatacca tcagcgttcc cgctctcttt aagtcggcgc ccaccgcgcc ccagcgcgca
      601 gtgtacgagc cgccagtcct gtttcggaca gaggatcact tccctggcag cggtgacaga
      661 ccgcaactct gagcgtgaag ctctaccaca ggaggactcc agtgagactc ttgtccagac
      721 tgttaattgg catacatgat accgccttgt gaaatgttaa agtttatttt ctgcaagcga
      781 cttgacatcg atgtcaagag tgtagatcct tatgtcttcc agtgctgatt caaaagctct
      841 ttggtcgggg cctggggaag ccaattgaat taatttatct gtgcaatatg gcagagctgt
      901 tattttatgg cctttattac agtgaacagt gttaccttgt taagatttat atatttatat
      961 gatcaaaagt gaccaagaaa ttaaagctgt attcttaaat cgtaacagtg gttcagtttt
     1021 ctgtagcatt ctgggaaaga tggcagattc aatattatgt tcagttttcc atagcgtgga
     1081 aacgcaatcg cttagcaccg gaagcggcca ggcgggccat ggaggaagga cccgcgttgt
     1141 aaaccaacgg aaacaagata gcaaactggg cgttttgtgc agagagttct gaagttgtat
     1201 ttgacagtat gactcagact tagtttatca aagcaagcat attaatgtat ggttgtcagt
     1261 ggtctataac acattcatta aaatgttaaa tttctttggc a
//
