LOCUS       NM_001013186            1544 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus bridging integrator 3 (Bin3), mRNA.
ACCESSION   NM_001013186 XM_341348
VERSION     NM_001013186.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1544)
  AUTHORS   Simionescu-Bankston,A., Leoni,G., Wang,Y., Pham,P.P.,
            Ramalingam,A., DuHadaway,J.B., Faundez,V., Nusrat,A.,
            Prendergast,G.C. and Pavlath,G.K.
  TITLE     The N-BAR domain protein, Bin3, regulates Rac1- and Cdc42-dependent
            processes in myogenesis
  JOURNAL   Dev Biol 382 (1), 160-171 (2013)
   PUBMED   23872330
REFERENCE   2  (bases 1 to 1544)
  AUTHORS   Routhier,E.L., Burn,T.C., Abbaszade,I., Summers,M., Albright,C.F.
            and Prendergast,G.C.
  TITLE     Human BIN3 complements the F-actin localization defects caused by
            loss of Hob3p, the fission yeast homolog of Rvs161p
  JOURNAL   J Biol Chem 276 (24), 21670-21677 (2001)
   PUBMED   11274158
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Dec 5, 2020 this sequence version replaced NM_001013186.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK355467.1, SRR26643286.40383.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                JAXUCZ010000015.1  51583474-51583559
            87-135              JAXUCZ010000015.1  51602971-51603019
            136-176             JAXUCZ010000015.1  51608332-51608372
            177-238             JAXUCZ010000015.1  51608733-51608794
            239-375             JAXUCZ010000015.1  51613310-51613446
            376-416             JAXUCZ010000015.1  51613940-51613980
            417-558             JAXUCZ010000015.1  51618786-51618927
            559-693             JAXUCZ010000015.1  51619050-51619184
            694-1544            JAXUCZ010000015.1  51621479-51622329
FEATURES             Location/Qualifiers
     source          1..1544
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p11"
     gene            1..1544
                     /gene="Bin3"
                     /note="bridging integrator 3"
                     /db_xref="GeneID:361065"
                     /db_xref="RGD:1308253"
     exon            1..86
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..840
                     /gene="Bin3"
                     /codon_start=1
                     /product="bridging integrator 3"
                     /protein_id="NP_001013204.1"
                     /db_xref="GeneID:361065"
                     /db_xref="RGD:1308253"
                     /translation="MSWIPFKIGQPKKQIVSKTVERDFEREYGKLQQLEEQTKRLQKD
                     MKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDFLRMVTALDTAMKRMDAFNQEKVNQ
                     IQKTVIEPLKKFGSIFPSLNMAVKRREQALQDYGRLQAKVEKYEEKEKTGPVLAKLHQ
                     AREELRPVREDFEAKNKQLLDEMPRFYNSRLDYFQPSFESLIRAQVIYYSEMHKIFGD
                     LTQQLDQPGHSDEHRERENETKLSELRALSIVADD"
     exon            87..135
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     exon            136..176
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     exon            177..238
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     exon            239..375
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     exon            376..416
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     exon            417..558
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     exon            559..693
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
     exon            694..1544
                     /gene="Bin3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actggccgaa tccggaagtg atcttcgaga atctactttt ctacagagga ccccggcagt
       61 cggcgtgagt ttaggaccat gagctggatt ccatttaaga tcgggcagcc caagaaacag
      121 attgtttcca aaacagtgga gagagacttt gaaagggagt atggaaaact gcagcagctg
      181 gaagagcaga ccaagcgcct gcagaaggac atgaagaaaa gcaccgatgc cgacctggcc
      241 atgtccaaat ctgctgtgaa gatatccctg gacctcctct ccaacccgct gtgtgagcag
      301 gatcaggact ttctgcgcat ggtgacagcc ctagacacag ccatgaagcg gatggatgct
      361 ttcaaccagg agaaggtgaa ccagatccag aagacggtga ttgaacccct gaaaaagttc
      421 ggcagcatat tcccaagcct taacatggca gtgaagcgac gggagcaggc cttgcaggac
      481 tacggcaggc tgcaggccaa ggtggagaag tacgaggaaa aggagaaaac tggtcccgtg
      541 ctggccaagc tccaccaggc ccgggaagag ctacggcctg tacgggaaga ctttgaggct
      601 aagaacaaac aactcctgga tgagatgcca cgattctata acagccgact tgactatttc
      661 cagcccagct ttgagtccct gatccgggca caggttatct actactcgga aatgcataag
      721 atctttggag acctgaccca gcagcttgac cagccaggcc attcggatga gcatcgagaa
      781 cgggaaaatg agaccaaact aagtgagctc cgagccctct ccatcgtggc tgatgactga
      841 gcccctgtcc ctcaggagtc cttggactct ttgggacaca gatggcattc gcataggctt
      901 tgctcctatg catcctagca ggcatggatt catggacctc ccaatggcca gccagttgga
      961 gacaggtggc cactattcta ccttgccagt tctctgactt aaatgtctcc atttccttga
     1021 gcctgatact aggagcctca caggctgctg tttccctgtg tccaatgttg ataagcaatg
     1081 tagaaaaacc ctggggccat tttacttcca gaaccgtcca gagtgtggta tagtatctgg
     1141 ccaacaggag cctttggaag ggcctgggct tcctgtgtaa cttgaggcct tagctgtcta
     1201 cctccagagg acctactcta ggaaagccac catcccctca ggactcttta gactgttggg
     1261 tgaggcacag tgccctgggt agcagaactc tggtctctca gccttgatgg gcccttcaca
     1321 ccaactcaac caacgctggt cccccctagg tccagtacag ggacaaaccc caggagttta
     1381 accttccttt gaactgggac tttgtctcta tctgtccact agaaaatggc acacattgag
     1441 ccactgccct cagagcaagg cttctgtcta acctgaatta ctggagcttt attttcactt
     1501 gttattggaa ttttattttc aagtaaaatt ttccagtaaa acaa
//
