LOCUS       NM_001012223            1951 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus bridging integrator 2 (Bin2), mRNA.
ACCESSION   NM_001012223 XM_345874
VERSION     NM_001012223.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1951)
  AUTHORS   Sanchez-Barrena,M.J., Vallis,Y., Clatworthy,M.R., Doherty,G.J.,
            Veprintsev,D.B., Evans,P.R. and McMahon,H.T.
  TITLE     Bin2 is a membrane sculpting N-BAR protein that influences
            leucocyte podosomes, motility and phagocytosis
  JOURNAL   PLoS One 7 (12), e52401 (2012)
   PUBMED   23285027
  REMARK    Erratum:[PLoS One. 2013;8(8).
            doi:10.1371/annotation/3bdc487b-5e25-4cd7-a354-b2952eec943d]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079406.1.
            
            On Feb 11, 2005 this sequence version replaced XM_345874.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079406.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1951
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1951
                     /gene="Bin2"
                     /note="bridging integrator 2"
                     /db_xref="GeneID:366988"
                     /db_xref="RGD:1306789"
     exon            1..123
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..1566
                     /gene="Bin2"
                     /codon_start=1
                     /product="bridging integrator 2"
                     /protein_id="NP_001012223.1"
                     /db_xref="GeneID:366988"
                     /db_xref="RGD:1306789"
                     /translation="MAEGKAGGAAGLFAKQMQKKFSRAQEKVLQKLGKTVETKDERFE
                     QSASNFYQQQAEGHRLYKDLKNFLSAVKVMRESSKRVSETLQEIYNSDWDGHEDLKAI
                     VGNNDLLWEDYEEKLADQALRTMENYVSQFSEVKERIAKRGRKLVDYDSARHHLEAVQ
                     NAKKKDEAKMAKAEEDFSKAQVVFEDLNQELLEELPVLYNSRIGCYVTVFQNISNLRD
                     VFYREMSKLNHSLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVQTCTAFSPVS
                     PVTSPTSPNALSVTSESESVSATAEELTSEAVGEDSCESEESLKDEEADEDQSETSSS
                     EEEEDEDEDEDEEESLAACNGPTPTPAPTPAPASPAAEVKSQEEAAPCSPTSSLGRGQ
                     TGKEHSPPGEVVLRARASSEGAEQSKRTASVQRTSAPPSRPPPPKASGGGLSSPPGSA
                     EASKACHPRASSDASSDPEPPETGEKEGTGSSGPKEPHASSTKSATQVVSNDENTEL"
     exon            124..204
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            205..259
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            260..354
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            355..450
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            451..558
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            559..644
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            645..720
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            721..803
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            804..1533
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
     exon            1534..1925
                     /gene="Bin2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctagaaacca caggaccaag ctgcgccccc gcagccggca ggatggcaga gggcaaggcg
       61 ggcggagcag ctggcctttt cgccaagcag atgcagaaga agttcagcag ggcccaggag
      121 aaggttctgc agaaattggg gaaaaccgta gaaaccaaag atgagcgatt tgaacaaagt
      181 gccagcaact tctaccaaca gcaggcagag ggccacaggc tgtacaaaga tctgaagaac
      241 ttccttagcg cagtcaaagt gatgcgtgag agctcaaaga gagtatcaga gaccctgcag
      301 gagatctaca acagcgactg ggatgggcat gaggacctga aggccatcgt ggggaacaac
      361 gatctcctct gggaagacta tgaagagaaa ctggctgacc aggctttgag gaccatggag
      421 aactatgtgt cacagttcag tgaggttaag gagagaattg ccaagcgggg ccggaaactg
      481 gtcgactacg atagtgcccg acaccacctg gaggctgtac agaatgctaa gaagaaggac
      541 gaggccaaga tggccaaggc agaagaagac ttcagcaagg cccaggttgt gtttgaagac
      601 ctgaaccagg aactcctgga ggagctgcct gttctttata acagtcgtat tggctgctac
      661 gtgaccgtct tccaaaacat ttccaacctg agagacgtct tctacaggga gatgagcaag
      721 ctgaaccaca gtctctatga agtgatgagc aaactggaga agcagcattc caacaaagtc
      781 tttgtggtaa agggcctatc aagcagcagc aggcgctcct tagtcatctc tcccccggtg
      841 caaacctgta ctgccttcag ccccgtcagc ccagtgacct cacctaccag ccccaatgct
      901 ctttctgtaa ccagtgagag tgagtctgtg tcagccactg cagaggagct gacctctgag
      961 gcagtgggag aggatagctg tgagagcgaa gagtccttga aagatgagga agcggacgaa
     1021 gaccagtctg aaacaagctc ttcagaggag gaggaagatg aggatgaaga tgaggacgaa
     1081 gaagagtctc tagcagcctg caacggcccc accccgaccc cggccccgac cccggccccg
     1141 gcctcccctg cagctgaggt gaagtcccag gaggaagctg ccccgtgctc cccaacttca
     1201 tccctgggca ggggtcagac cgggaaagag cattctcccc ccggggaagt ggtcctccgt
     1261 gcccgcgcct cgagcgaggg ggcagaacag agcaaaagaa cagcgtccgt ccagcggacc
     1321 tctgctccgc ccagcaggcc tccaccaccc aaggcctcag gcggtgggct ctccagcccc
     1381 ccaggatcgg cagaggcctc caaggcatgc caccccaggg cctcttcaga tgcctcttcg
     1441 gatccagaac ccccagagac cggagaaaag gagggcactg gcagctcggg ccccaaagag
     1501 ccacatgcct cctccaccaa gagcgccacc caggtagttt caaatgatga aaacacagaa
     1561 ctctgaagag aaaccaccaa ggacctgacc tcgtctgccc agagaagttt ctgaagccga
     1621 gggccatggg tacaagcctc acgaaattca cgttctcggg cagtgtggat ccgtgccctc
     1681 ggaatcctgc cattgctgga gtctgcagca gcctgaggga ggaaggcacc acacacaggg
     1741 aacgtttttt accaggggct tgagcagtaa tagaagcagg gctgtaatga cgccaaggaa
     1801 aagcttcctt tggcgcgtcc acacgtttgg gggacaggcg tccagcccac cactcactgg
     1861 gcaagagtta aagcggaaac atttttcaga ctactaaata aagtgtggtt ttgactaggc
     1921 gtggaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
