LOCUS       NM_001106226            5516 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus BRD4 interacting chromatin remodeling complex
            associated protein (Bicra), mRNA.
ACCESSION   NM_001106226 XM_001074112 XM_214817
VERSION     NM_001106226.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5516)
  AUTHORS   Alpsoy,A. and Dykhuizen,E.C.
  TITLE     Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its
            paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes
  JOURNAL   J Biol Chem 293 (11), 3892-3903 (2018)
   PUBMED   29374058
REFERENCE   2  (bases 1 to 5516)
  AUTHORS   Rahman,S., Sowa,M.E., Ottinger,M., Smith,J.A., Shi,Y., Harper,J.W.
            and Howley,P.M.
  TITLE     The Brd4 extraterminal domain confers transcription activation
            independent of pTEFb by recruiting multiple proteins, including
            NSD3
  JOURNAL   Mol Cell Biol 31 (13), 2641-2652 (2011)
   PUBMED   21555454
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 24, 2009 this sequence version replaced NM_001106226.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.981.1,
                                           SRR26643299.1275.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                JAXUCZ010000001.1  85814542-85814582   c
            42-84               JAXUCZ010000001.1  85814392-85814434   c
            85-150              JAXUCZ010000001.1  85811046-85811111   c
            151-2112            JAXUCZ010000001.1  85805828-85807789   c
            2113-2288           JAXUCZ010000001.1  85805268-85805443   c
            2289-2918           JAXUCZ010000001.1  85797738-85798367   c
            2919-2920           JAXUCZ010000001.1  85797579-85797580   c
            2921-3099           JAXUCZ010000001.1  85797400-85797578   c
            3100-3101           JAXUCZ010000001.1  85797169-85797170   c
            3102-3209           JAXUCZ010000001.1  85797061-85797168   c
            3210-3271           JAXUCZ010000001.1  85795400-85795461   c
            3272-3420           JAXUCZ010000001.1  85794290-85794438   c
            3421-3515           JAXUCZ010000001.1  85794004-85794098   c
            3516-3618           JAXUCZ010000001.1  85793717-85793819   c
            3619-5515           JAXUCZ010000001.1  85790093-85791989   c
FEATURES             Location/Qualifiers
     source          1..5516
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..5516
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /note="BRD4 interacting chromatin remodeling complex
                     associated protein"
                     /db_xref="GeneID:292622"
                     /db_xref="RGD:1306385"
     CDS             1..4731
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /note="glioma tumor suppressor candidate region gene 1;
                     BRD4 interacting chromatin remodelling complex associated
                     protein"
                     /codon_start=1
                     /product="BRD4-interacting chromatin-remodeling
                     complex-associated protein"
                     /protein_id="NP_001099696.2"
                     /db_xref="GeneID:292622"
                     /db_xref="RGD:1306385"
                     /translation="MDDEDGRCLLDVICDPQALNDFLHGSEKLDSDDLLDAPVEAQSA
                     FYEGPGLHVQEAAGNHLNPEPSQPAPSVDLDFLEDDILGSPAAGGGGGGGGGPDQPCD
                     ILQQSLQEANITEQTLEAEAELDLGPFQLPTLQPADGGAGATGAAGAAAVTAGPQALF
                     PGSADLLGLQAPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTLQPIQGLQGLP
                     NGSPGGATAATLGLAPIQVVGQPVMALNPPTSQLLAKQVPVSGYLASAAGPSEPVTLA
                     SAGVSPQGAGLVIQKNLPAAVTTTLNGNSVFAGTGSATAAASGAPSGQPLAVAPGLGT
                     SPLVQAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFTPTGATLTIQGEPGTLPQQP
                     KAPQNLTFMAAGKAGQNVVLSSFPAPALQANVFKQPPVTTTGTAPPQPPGALSKPMSV
                     HLLNQGSSIVIPAQHMLPGQNQFLLPGTSAVQLPQSLSALPANVGGQILTAAAPHAGG
                     QLIANPILTNQNLAGPLSLGPVLAPHSGAHSAAHILSAAPIQVGQPALFQMPVSLATG
                     SLPTQSQPAPTGPTATTVLQGVTLPPSAVAMLNTPDGLVQPSTPAATTGEATPVLAVQ
                     PATQVPPAVTTPLPMGLQQSPAQQPPQAPTPQAATQPQATPPQASPGLASSPEKIVLG
                     QAPPAATTAILTQDSLQMFLPQERSQQPLSTEGPHLSVPASVIVSAPPPAQDPALATP
                     VTKGAGLGAQTPDNRASPAPAPQIPAAAPLKAPGPASSPSLPHQAPLGDSPHMPSPHP
                     ARPPSRPPSRPHSRPPSQPQSLTCPPSEPTLHPCPPPQGPPTLPGIFVIQNQLGAPPP
                     ASTPAPTAPGPPQPPLRPPSQPPEGPLPPASHLPPASTPSAVASSSEPSTRLPVPTPP
                     DFQFPPGQGPHKSPTPPPALHLVPEPTAPPPPPPRTFQMVTAPFPALPQPKALLERFH
                     QVPSGIILQNKAGGTPTTPQTSTTLGTLTSPTASVLVSGQAPPGTPAASSHAPASTPM
                     ATTGLPPLLPAENKAFASNLPTLSVAKATVSGPGKSPAMQYDSKLGSLKKQPLLQPSK
                     EACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPNDYHKVDEEFE
                     TVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKE
                     KPDEYVSSSRSLGFPVPVSSEGHRLPSHGPSSSSSTSGTSAQPPPHPPTKLVIRHGGA
                     GGSPSVTWARASSSLSSTSSSSSSSSVASSLDADEDGPMPSRSRPPIKTYEARSRIGL
                     KLKIKQEAGLSKVVHNTALDPVHQPLPAPTPAKGAEPPPHPAPPPLPPATQAQMNGTL
                     DHPPPIVRKPTVPASCPRLPLRKTYRENMGDPSATEGAQGRPRGAGSPTPLPTKVDEA
                     TSGLIRELAAVEDELYQRVLKGGPPPPETPASATSQGPTESGWEAPMLPPTKRRKSES
                     PDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAGPYPHTGPTPGTPTSPA
                     PLHRPDAFPPSSHNGGLGARTLNR"
     exon            1..41
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            42..84
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            85..150
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            151..2112
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2113..2289
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2919
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2920..3100
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3101..3210
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3211..3272
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3273..3421
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3422..3516
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3517..3619
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3620..5516
                     /gene="Bicra"
                     /gene_synonym="Gltscr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggatgatg aggatgggag atgcttacta gacgtgattt gtgaccctca ggccctcaat
       61 gacttcttgc atggatccga aaagctggac agtgatgacc tcctggatgc ccctgtggag
      121 gcccaaagtg ccttctatga aggtcctggg ctccatgtgc aggaagctgc cggcaaccac
      181 ctgaaccctg agcccagcca acctgccccc agcgtggacc tggacttcct agaagatgat
      241 atcctgggct cccctgcagc aggaggaggt ggagggggcg gcgggggccc agaccagccc
      301 tgtgacattc ttcagcagag tcttcaggag gccaacatca cagagcagac cctggaggct
      361 gaggctgaac tggacctggg ccccttccag ctgcccaccc tacagcccgc tgacggcggg
      421 gcaggtgcta ctggagctgc aggagctgct gcagtgaccg cagggcccca ggctctcttc
      481 ccaggcagcg cagatctgct ggggctgcaa gccccgccca ctgtacttac ccaccaggcc
      541 ttggtgccac cccaggatgt ggtcaacaag gccctgagcg tccagccctt cctacagccc
      601 gtgggcctgg gcaatgtgac ccttcagccc attcaaggcc tccagggcct tcccaatggc
      661 agtcctgggg gcgctacagc agccactttg ggtctggcac ctattcaagt ggtgggccag
      721 cccgtcatgg ctctcaatcc acccacctcc cagctcttgg caaagcaggt gcctgtcagt
      781 ggctacctgg cctccgcagc tggtccttca gagccagtga cactggcatc tgccggcgtg
      841 tccccccagg gagccggcct agtcatccag aaaaatcttc cagccgcagt gaccaccaca
      901 ctcaacggga actcagtctt tgccgggaca gggtctgcca ctgcagcagc cagtggggca
      961 ccctcgggac agccgctggc ggtggccccg ggccttggca cgtcaccact ggtacaagca
     1021 cccaatgtga ttttacacag aacccctacg cccatccagc ccaagcctgc aggggtactg
     1081 ccccccaaac tctaccagct gacccccaag cccttcaccc ccacgggagc cacccttacc
     1141 atccagggtg agccaggcac cttgccccag cagcctaagg ccccccagaa cctgactttt
     1201 atggccgcag gcaaagctgg tcagaacgtg gtgctgtcta gcttcccagc accggctttg
     1261 caggcgaatg tattcaagca gccaccagtc accaccacgg ggacagcccc gccacagcca
     1321 cccggggccc tcagcaaacc catgagcgtc cacctcctca atcaaggcag tagcatcgtg
     1381 atcccagccc agcacatgct gcctggccag aaccagttct tgctgccagg cacctcggct
     1441 gtacaactac cccagtcact ttctgccctg cctgccaacg tgggaggcca gatcctcaca
     1501 gccgcagcac cacatgcagg tggacagctc attgccaacc caatcctcac caaccagaac
     1561 ctggcaggcc cactaagtct gggcccagtg ctggcacccc actctggggc acacagcgct
     1621 gcgcacatcc tctctgcagc tcccatccag gtgggccagc ctgccctctt ccagatgcct
     1681 gtgtcgctgg ccactggcag cctgcccact cagagccagc cagctcccac tggccccaca
     1741 gccaccaccg tcctccaggg tgtcaccctg cctcccagtg ctgtggccat gcttaacaca
     1801 cctgatgggc tagtgcagcc ctcaacccca gctgccacca ctggggaagc cacacctgtt
     1861 ctggccgttc aacctgccac ccaggtaccc cctgctgtca ccacaccact gcctatgggt
     1921 ctccaacagt caccggcaca gcagcctcca caggccccta ctccacaggc ggccacccag
     1981 cctcaggcca cccctcctca ggccagtcca ggcctggcat ccagcccaga gaagatagtc
     2041 ctggggcagg cgccccctgc ggccacaacg gccatcctca ctcaggattc cctccagatg
     2101 ttcctgcccc aggagaggag ccagcagccc ctctctacag agggtcccca cctctcggtg
     2161 cctgcctccg tcatagtcag cgccccgcct cctgcccaag acccagccct ggccacgccc
     2221 gtcaccaaag gagctggcct tggcgctcag acccccgaca accgggcttc cccagctcca
     2281 gctccccaga tcccagcagc tgctccactg aaagcccctg gccctgcctc ctccccatca
     2341 ctacctcacc aggcccccct gggagacagt ccccacatgc cctccccaca ccctgccagg
     2401 cccccttccc gcccaccctc gagaccccac tcacgccctc catcccagcc ccagagcctg
     2461 acctgcccac cctccgagcc caccctgcac ccttgccctc caccccaggg tcccccaact
     2521 ctacctggca tctttgtcat ccagaatcaa ttgggtgccc caccaccagc cagcacccca
     2581 gcccccacag ccccaggccc accccagccc cctctgcgac ccccatccca gcctcctgag
     2641 ggcccattgc ccccagcctc ccacctccct cctgcctcca ccccttccgc tgtggcctcc
     2701 tcctctgagc cttctaccag gttgccagtc cccacacccc ctgacttcca gttcccacca
     2761 ggccagggac cccataagtc ccccactcca ccaccagccc tccatttggt ccctgagccc
     2821 acggcacccc ctcctccacc acctcggacc ttccagatgg taactgcccc cttcccagcg
     2881 ctgccccagc caaaagcact tctggaacga ttccaccagg tgccatctgg gattattctc
     2941 cagaataagg ctgggggtac tcccaccacc ccacagacat ccaccaccct ggggaccctc
     3001 accagtccta ctgcctctgt gctagtcagt ggacaggcac cacctgggac tcctgctgcc
     3061 tctagccatg ccccagcctc cacacctatg gccaccacag gtctccctcc tctacttcct
     3121 gccgaaaaca aagcttttgc cagcaacctt ccaaccctga gtgtggccaa agctactgtg
     3181 tctgggccag ggaagtcccc agcgatgcag tatgacagca agttgggtag cctgaagaaa
     3241 cagccccttc tgcaacccag caaagaagcc tgcttcctgg agcatctgca caaacatcag
     3301 ggttctgtcc tgcaccctga ttacaagaca gctttcccct cctttgagga cgccctccat
     3361 cgcctcctgc cctaccatgt ctaccaaggc gccctcccct cccccaatga ctaccataaa
     3421 gtggatgaag aatttgagac tgtctctacg cagctgctca aacgtaccca ggccatgctc
     3481 aataaatatc ggcttttgct tctggaagag tccaggagag tcagtccttc cgcagagatg
     3541 gttatgatcg accgaatgtt cattcaggag gagaagacca cccttgcctt ggataagcag
     3601 ctcgccaagg agaaacctga tgagtatgtg tcttcctccc gctcccttgg cttccctgtc
     3661 ccagtgtctt ccgagggtca ccggctcccc agccacggcc catcttcttc atcctccaca
     3721 tctggaacat ctgcccagcc ccctcctcac ccgcccacca agctagtgat ccggcatggc
     3781 ggagctggcg gctccccctc agtgacctgg gcccgggcat catcctcctt gtcatcaacg
     3841 tcctcatcct catcctcatc ctctgtcgcc tcatccctgg acgcagatga ggacggcccc
     3901 atgccctccc gtagccggcc acccattaag acctatgagg cccggagccg cattggcctc
     3961 aaactcaaga tcaagcagga ggcggggctc agcaaggtgg tgcacaacac tgcattggat
     4021 cctgtacacc agcccttgcc tgctccaacc cctgcaaaag gggctgaacc tccgccacac
     4081 ccagctcctc ccccactccc acctgccacc caggcacaga tgaatggcac tctggaccat
     4141 cccccaccca tagtacgcaa acccacggtg cctgcgtcct gcccacgtct accactgcgc
     4201 aagacctacc gagaaaacat gggcgatcct agtgccactg agggtgcaca gggacggccg
     4261 cggggtgcgg gcagccccac cccactgccc accaaggtag acgaagccac cagtgggctg
     4321 atccgggagc tggcagcggt ggaggacgaa ttgtatcagc gggttctgaa gggcggccca
     4381 ccacccccgg agaccccagc ctctgctact agccaaggcc ccacagaatc tggttgggaa
     4441 gcacccatgc tacccccaac caaacgacgc aagtctgagt ccccggacgt ggaccaggcc
     4501 agcttctcta gtgacagccc gcaggatgat acactcactg agcatttgca gagtgccatc
     4561 gacagcatcc ttaacctgca gcaggccccc ggccggacac ctgcaggccc atacccccat
     4621 acgggcccca cgcctggcac ccccacatcc ccagctcctc tgcacaggcc tgacgccttc
     4681 ccaccctcta gtcacaatgg tggcctcggc gccaggacgt tgaacagata acactgggct
     4741 gctcctgcag cccttatcgg gtgccgccaa ccccacttcc aggagagcag cctgacagcc
     4801 aacctccacc tcccaggggc actaacccag ttcccctgac aattcttgcc taagttattt
     4861 gagtcacaaa ggcctcccca cctttctgct tccacgttgg ctagagattt gggatggggt
     4921 gtgggttttc taggggaagg tgggctataa ggtacaacgt ccacctggca cagccaggac
     4981 aggggatacg tgagtgttgt ccaggactgg gctactaggg tgatgcactg gtaacatctg
     5041 aatacaaggt cttgtctgtt tggcttcatg gatcactgtc caaggcactg agagctggga
     5101 gagaccttca gagaggctcg actctcatcc tgttgcccac agtccctgga aaattaggaa
     5161 gcagggactc aagccagtgt tccaaagtac ctgcatccca tccaaacgtg cactcgcctg
     5221 agtcatcctg tgtgagtgtg tgcgcgcacg agagagagag cgattcccac caaccccatc
     5281 cctccagagg aacaagacac ggggtcttcc ttccttctcc caagcagtct tccctgtatt
     5341 cttcttgcct ccagcccacc acgccacgtt ttgaaatctt ggagacaaaa ctagtactgt
     5401 aagataaaga tttttttttg tactgtattt attgtgtata acaatttttt aagggagaat
     5461 tctgtacatc tagaactctt gtaaattaaa agctgatcct tttttttaaa actgta
//
