LOCUS       NM_001037554             794 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus brain expressed, X-linked 4 (Bex4), mRNA.
ACCESSION   NM_001037554 XM_580221
VERSION     NM_001037554.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 794)
  AUTHORS   Lee,S., Kang,H., Shin,E., Jeon,J., Youn,H. and Youn,B.
  TITLE     BEX1 and BEX4 Induce GBM Progression through Regulation of Actin
            Polymerization and Activation of YAP/TAZ Signaling
  JOURNAL   Int J Mol Sci 22 (18), 9845 (2021)
   PUBMED   34576008
  REMARK    GeneRIF: BEX1 and BEX4 Induce GBM Progression through Regulation of
            Actin Polymerization and Activation of YAP/TAZ Signaling.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 794)
  AUTHORS   Yu,W., Yaping,L., Mingjun,W., Jie,H., Xiaogang,L. and Gang,L.
  TITLE     BEX4 upregulation alters Sertoli cell growth properties and protein
            expression profiles: An explanation for cadmium-induced testicular
            Sertoli cell injury
  JOURNAL   J Biochem Mol Toxicol 31 (7) (2017)
   PUBMED   28295929
REFERENCE   3  (bases 1 to 794)
  AUTHORS   Lee,J.K., Lee,J., Go,H., Lee,C.G., Kim,S., Kim,H.S., Cho,H.,
            Choi,K.S., Ha,G.H. and Lee,C.W.
  TITLE     Oncogenic microtubule hyperacetylation through BEX4-mediated
            sirtuin 2 inhibition
  JOURNAL   Cell Death Dis 7 (8), e2336 (2016)
   PUBMED   27512957
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 794)
  AUTHORS   Alvarez,E., Zhou,W., Witta,S.E. and Freed,C.R.
  TITLE     Characterization of the Bex gene family in humans, mice, and rats
  JOURNAL   Gene 357 (1), 18-28 (2005)
   PUBMED   15958283
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Mar 15, 2021 this sequence version replaced NM_001037554.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC128698.1, DY314412.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               JAXUCZ010000021.1  103923609-103923734
            127-203             JAXUCZ010000021.1  103924107-103924183
            204-794             JAXUCZ010000021.1  103924451-103925041
FEATURES             Location/Qualifiers
     source          1..794
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq32"
     gene            1..794
                     /gene="Bex4"
                     /note="brain expressed, X-linked 4"
                     /db_xref="GeneID:501624"
                     /db_xref="RGD:1564749"
     exon            1..126
                     /gene="Bex4"
                     /inference="alignment:Splign:2.1.0"
     exon            127..203
                     /gene="Bex4"
                     /inference="alignment:Splign:2.1.0"
     exon            204..794
                     /gene="Bex4"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..565
                     /gene="Bex4"
                     /note="BEX1-like 1; brain-expressed X-linked protein 4
                     homolog; BEX1-like protein 1; brain expressed gene 4"
                     /codon_start=1
                     /product="protein BEX4"
                     /protein_id="NP_001032643.1"
                     /db_xref="GeneID:501624"
                     /db_xref="RGD:1564749"
                     /translation="MASKVKQVILDLTVEKDKKNKKGGKASKQSEEESHHLEEVENKK
                     PGGNVRRKVRRLVPNFLWAIPNRHVDHSEGGEEVGRFVGQVMEAKRKSKEQQMRPYTR
                     FRTPEPDNHYDFCLIP"
ORIGIN      
        1 cgctcactct cttctgcccg ccatccctaa cggaggcacc tgttcctggt ggcgcagctc
       61 ctggtggcgc agagcacgcg ggcccgggca gcgcggaaag caggaggagg aggaagagca
      121 gaacaggtct gaggaccaga agcttcgcgg cacacctggt ggtgagcatc gctaggaaga
      181 ggagaaggca aggataggcc caggagtaat ggcgtccaaa gtcaaacaag tcatactgga
      241 tctcactgtg gagaaagaca agaaaaacaa aaaaggtggg aaggcctcca aacaaagtga
      301 agaagaatcc caccatctgg aagaggttga aaacaagaag cctgggggca atgtcaggag
      361 gaaagtcagg cgacttgtgc ctaactttct atgggccata cctaataggc atgttgatca
      421 cagtgaaggg ggagaggagg ttgggagatt cgtagggcag gtgatggaag ccaagagaaa
      481 gtctaaggag caacagatga ggccttacac gcgtttccga acccctgaac ctgacaatca
      541 ttacgacttt tgcctcatac cttgaaatct aaggttttct ctgggctcat aaaatggcca
      601 ctgttttaca agcttgtatt ttgtggggta tcttttctgt aaacttttgg tgtttccact
      661 taacgatttc tacgtaaaca ttgtttaatt gttgcattga attctaaaca ttcctatcag
      721 catggcaatt taacccattt tagaaaaaaa tctttttcgt aatttgaaat taataaagca
      781 aatttaaaaa gcaa
//
