LOCUS       NM_001037365             817 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus brain expressed X-linked 1 (Bex1), mRNA.
ACCESSION   NM_001037365 XM_577023
VERSION     NM_001037365.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   He,M., Wang,Y., Shen,J., Duan,C., Lu,X. and Li,J.
  TITLE     Bex1 attenuates neuronal apoptosis in rat intracerebral hemorrhage
            model
  JOURNAL   Pathol Res Pract 214 (4), 527-535 (2018)
   PUBMED   29572119
  REMARK    GeneRIF: Bex1 may play the neuronal anti-apoptosis role following
            intracerebral hemorrhage (ICH), implying a novel molecular target
            for the therapy of ICH.
REFERENCE   2  (bases 1 to 817)
  AUTHORS   Fernandez,E.M., Diaz-Ceso,M.D. and Vilar,M.
  TITLE     Brain expressed and X-linked (Bex) proteins are intrinsically
            disordered proteins (IDPs) and form new signaling hubs
  JOURNAL   PLoS One 10 (1), e0117206 (2015)
   PUBMED   25612294
  REMARK    GeneRIF: Bex family members play important roles in the formation
            of protein network hubs.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 817)
  AUTHORS   Vilar,M., Murillo-Carretero,M., Mira,H., Magnusson,K., Besset,V.
            and Ibanez,C.F.
  TITLE     Bex1, a novel interactor of the p75 neurotrophin receptor, links
            neurotrophin signaling to the cell cycle
  JOURNAL   EMBO J 25 (6), 1219-1230 (2006)
   PUBMED   16498402
REFERENCE   4  (bases 1 to 817)
  AUTHORS   Alvarez,E., Zhou,W., Witta,S.E. and Freed,C.R.
  TITLE     Characterization of the Bex gene family in humans, mice, and rats
  JOURNAL   Gene 357 (1), 18-28 (2005)
   PUBMED   15958283
REFERENCE   5  (bases 1 to 817)
  AUTHORS   Feng,Y., Liang,H.L. and Wong-Riley,M.
  TITLE     Differential gene expressions in the visual cortex of postnatal day
            1 versus day 21 rats revealed by suppression subtractive
            hybridization
  JOURNAL   Gene 329, 93-101 (2004)
   PUBMED   15033532
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Mar 15, 2021 this sequence version replaced NM_001037365.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV770079.1, EV776776.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN12840105
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               JAXUCZ010000021.1  104012002-104012143 c
            143-219             JAXUCZ010000021.1  104011556-104011632 c
            220-817             JAXUCZ010000021.1  104010639-104011236 c
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq32"
     gene            1..817
                     /gene="Bex1"
                     /gene_synonym="Bex; Bex1h; Bex2"
                     /note="brain expressed X-linked 1"
                     /db_xref="GeneID:501625"
                     /db_xref="RGD:1564643"
     exon            1..142
                     /gene="Bex1"
                     /gene_synonym="Bex; Bex1h; Bex2"
                     /inference="alignment:Splign:2.1.0"
     exon            143..219
                     /gene="Bex1"
                     /gene_synonym="Bex; Bex1h; Bex2"
                     /inference="alignment:Splign:2.1.0"
     exon            220..817
                     /gene="Bex1"
                     /gene_synonym="Bex; Bex1h; Bex2"
                     /inference="alignment:Splign:2.1.0"
     CDS             225..611
                     /gene="Bex1"
                     /gene_synonym="Bex; Bex1h; Bex2"
                     /note="EG2RVC; brain-expressed X-linked protein 1 homolog;
                     brain expressed gene 1; brain-expressed X-linked protein 2
                     homolog; protein BEX2; brain expressed X-linked 2"
                     /codon_start=1
                     /product="protein BEX1"
                     /protein_id="NP_001032442.1"
                     /db_xref="GeneID:501625"
                     /db_xref="RGD:1564643"
                     /translation="MESKDQGAKNLNMENDHQKKEEKEEKPQDTIKREPVVAPTFEAG
                     KNCAPRGGRRRFRVRQPISHYRWDLMHRVGEAQGRMRDENVQRFGEDMRHLMGKLRER
                     QLSHSLRAVSTDPPHHDHNDEFCLMP"
ORIGIN      
        1 gtctccgacc tgccctcgct cactctcttc tgcccgccat ccctaacgga ggcacctgtt
       61 cctggtggcg cagctcctgg tggcgcagag cacgcgggcc cgggcagcgc ggaaagcagg
      121 aggaggagga agagcagagc aggtctgagg accagaagct tcgcggcaca cctggtggtg
      181 agcatcgcta ggaagaggag aaggcaagga taggcccagg agaaatggag tccaaagatc
      241 aaggagcaaa aaatctcaac atggaaaatg accatcagaa aaaggaggaa aaggaagaaa
      301 agccgcaaga taccatcaaa agggagccgg ttgtggcccc cacttttgag gctggcaaaa
      361 attgtgcgcc tagaggaggt cgcaggcggt tccgcgttag gcagcccatt tcccactata
      421 gatgggacct gatgcacagg gttggagagg cccagggcag gatgagagat gagaatgtgc
      481 aaaggtttgg ggaggatatg agacacctca tgggcaagtt gagggaaagg cagctgagcc
      541 atagtctgcg ggcggtgagc actgaccccc ctcaccatga ccacaatgat gagttttgcc
      601 ttatgccctg agtcctgagg ttgtctctga agatgctatg gggacccctg ctttgtgatg
      661 tacaagtttt gaggttactc cttttatgta gatctcttcc tgttaccaac ttctaagtga
      721 aacttgtgtt ttttactcgg cctgtaattc ttttatcaga tgcatgggaa ggtccatatg
      781 acatattgtg aacctaataa agcagattga aaaggca
//
