LOCUS       NM_024163               2827 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus brain-enriched guanylate kinase-associated
            (Begain), transcript variant 2, mRNA.
ACCESSION   NM_024163
VERSION     NM_024163.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2827)
  AUTHORS   Katano,T., Fukuda,M., Furue,H., Yamazaki,M., Abe,M., Watanabe,M.,
            Nishida,K., Yao,I., Yamada,A., Hata,Y., Okumura,N., Nakazawa,T.,
            Yamamoto,T., Sakimura,K., Takao,T. and Ito,S.
  TITLE     Involvement of Brain-Enriched Guanylate Kinase-Associated Protein
            (BEGAIN) in Chronic Pain after Peripheral Nerve Injury
  JOURNAL   eNeuro 3 (5) (2016)
   PUBMED   27785460
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2827)
  AUTHORS   Yao,I., Iida,J., Nishimura,W. and Hata,Y.
  TITLE     Synaptic and nuclear localization of brain-enriched guanylate
            kinase-associated protein
  JOURNAL   J Neurosci 22 (13), 5354-5364 (2002)
   PUBMED   12097487
REFERENCE   3  (bases 1 to 2827)
  AUTHORS   Deguchi,M., Hata,Y., Takeuchi,M., Ide,N., Hirao,K., Yao,I.,
            Irie,M., Toyoda,A. and Takai,Y.
  TITLE     BEGAIN (brain-enriched guanylate kinase-associated protein), a
            novel neuronal PSD-95/SAP90-binding protein
  JOURNAL   J Biol Chem 273 (41), 26269-26272 (1998)
   PUBMED   9756850
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF064868.1 and BP478305.1.
            
            On Dec 7, 2007 this sequence version replaced NM_024163.1.
            
            Transcript Variant: This variant (2) represents the longer
            transcript and encodes the longer isoform (2).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF064868.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760396 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2590              AF064868.1         36-2625
            2591-2827           BP478305.1         1-237               c
FEATURES             Location/Qualifiers
     source          1..2827
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..2827
                     /gene="Begain"
                     /note="brain-enriched guanylate kinase-associated"
                     /db_xref="GeneID:79146"
                     /db_xref="RGD:708347"
     exon            1..105
                     /gene="Begain"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..1899
                     /gene="Begain"
                     /note="isoform 2 is encoded by transcript variant 2;
                     brain-enriched guanylate kinase-associated protein"
                     /codon_start=1
                     /product="brain-enriched guanylate kinase-associated
                     protein isoform 2"
                     /protein_id="NP_077077.1"
                     /db_xref="GeneID:79146"
                     /db_xref="RGD:708347"
                     /translation="MWTGGRRPGRLRRAASAADMEKLSALQEQKGELRKRLSYTTHKL
                     EKLETEFDSTRHYLEIELRRAQEELDKVTEKLRRIQSNYMALQRINQELEDKLYRMGQ
                     HYEEEKRAMSHEIVALNSHLLEAKVTIDKLSEDNELYRKDCNLAAQLLQCSQTYGRVH
                     KVSELPSDFQQRVSLHMEKHGCSLPSPLCHPSYADSVPTCVIAKVLEKPDPGSLSSRM
                     SDASARDLAYRDGVENPGPRPPYKGDIYCSDTALYCPDERDHDRRPSVDTPVTDVGFL
                     RAQNSTDSLAEEEEAEAAAFPEAYRREAFQGYAASLPTSSSYSSFSATSEEKEHAQAS
                     TLTASQQAIYLNSREELFSRKPPSATYGSSPRYAKAAATLGSPLEAQVAPGFARTVSP
                     YPAEPYRYPASQQALMPPNLWSLRAKPSGNRLAAREDIRGQWRPLSVEDVGAYSYQAG
                     AAGRAASPCNFSERFYGGGGGGGSPGKNAEGRASPLYASYKADSFSEGDDLSQGHLAE
                     PCFLRAGGDLSLSPSRSADPLPGYATSDGDGDRLGVQLCGPGSSPEPEHGSRDSLEPS
                     SMEASPEMHPPTRLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN"
     exon            106..134
                     /gene="Begain"
                     /inference="alignment:Splign:2.1.0"
     exon            135..296
                     /gene="Begain"
                     /inference="alignment:Splign:2.1.0"
     exon            297..363
                     /gene="Begain"
                     /inference="alignment:Splign:2.1.0"
     exon            364..471
                     /gene="Begain"
                     /inference="alignment:Splign:2.1.0"
     exon            472..555
                     /gene="Begain"
                     /inference="alignment:Splign:2.1.0"
     exon            556..2823
                     /gene="Begain"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctgcggga agcggggcgc tggggagccc cggccgcggg ctcgggcgcg cagagccggg
       61 gccatgtgga cgggcggccg gcggccgggc cggcttcgcc gggcggcctc tgccgcagac
      121 atggagaaac tcagtgcgct gcaggaacag aagggcgagc tgcgcaagcg cctgtcctac
      181 accacgcaca agttggagaa gctggagacg gagtttgact ccacccgcca ctatctggag
      241 attgagctga ggcgcgcaca ggaggagctg gacaaggtca ccgagaaact gcgcaggatt
      301 cagagcaact acatggcact ccagaggatc aaccaagagc tggaagacaa gctgtaccgg
      361 atgggccagc actatgagga agagaagcgt gccatgagcc acgagattgt cgccctcaac
      421 agccacctgc tggaggctaa ggtgaccatt gacaagctgt cagaagacaa cgagctctat
      481 aggaaggact gcaatctagc ggcccagctg ctgcagtgca gccagaccta cggcagggtc
      541 cataaggtgt ccgagctgcc ctcggacttc cagcagcgtg tgagcctgca tatggagaag
      601 catggctgca gcctgccgtc cccactgtgc catccgtcct acgccgacag cgtgcccacc
      661 tgcgtcatcg ccaaggtgct ggagaagccc gaccctggca gcctgtcctc gcgcatgtcg
      721 gatgcctcgg cccgcgacct ggcctaccgc gacggagtgg agaacccggg cccgcgaccc
      781 ccgtacaagg gagacatcta ctgcagcgac acggctctct actgccctga cgagcgagat
      841 cacgaccggc ggcccagcgt ggacacgccg gtgaccgacg tgggcttcct gcgtgcgcag
      901 aattccaccg acagcctggc ggaagaggag gaggccgagg cggcggcctt cccggaggcc
      961 taccgtcgcg aggccttcca gggctacgcg gcctcgctgc ccacgtccag ctcctactcc
     1021 agcttcagcg ccacgtccga ggagaaggag cacgcgcagg ccagcacgct gaccgcctcg
     1081 cagcaggcca tctacctgaa cagccgcgaa gagctcttca gccgcaagcc gccctccgcc
     1141 acctacggca gcagccctcg ctacgccaag gccgcggcca ccctgggctc cccgctcgag
     1201 gcccaggtag ccccaggctt cgctcggact gtgtctccgt acccggccga gccctaccgc
     1261 tatccggcct cccagcaggc tctcatgcct cccaacctgt ggagcctgcg ggccaagccg
     1321 agcggtaacc ggcttgccgc ccgggaggac attcgaggcc agtggcggcc cctgagcgtg
     1381 gaggatgtgg gcgcctactc ttaccaggcc ggcgctgcag gccgcgccgc ctcgccctgc
     1441 aacttctcag aacgtttcta cggcggcggt ggcggcggcg gcagcccggg caagaatgcc
     1501 gagggccgtg ccagccccct ctatgccagc tacaaagccg atagtttctc ggagggcgat
     1561 gacctctccc agggtcatct ggccgagccc tgcttcctcc gagcgggtgg tgatctgagc
     1621 ctcagcccca gccgttcagc tgatcctctc cctggctatg ccaccagtga cggggatggg
     1681 gataggctcg gggtgcagct gtgtgggcct ggcagtagcc cggagcccga gcacggctcc
     1741 cgggattccc tggagcctag ctccatggag gcctctcccg aaatgcaccc tccaacccgc
     1801 ctcagccccc agcaggcctt cccaaggact ggaggctctg ggctgagccg caaggacagt
     1861 ctcactaagg cccagctcta cggaaccctg ctcaactgac tgccatcagc aggctgcagt
     1921 caggggctcc ctaccaccct gccccatata gggagtagct aaccccctcg tcccaacccc
     1981 tgctaaggaa ctccagttcc agttccagtt cctgttccag ttccagttcc tgttccagtt
     2041 cctgttccag ttccagttcc cgttcctgtt ccagttcctg ttccagttcc agttcccgtt
     2101 ccagttcccg ttcctgttcc agttcccgtt ccagttcctg ttccagttcc agttcctcct
     2161 gaccctgtta ctaacacccc agtagaacct gaaaagaccc cctctgccaa tcgtcttgtc
     2221 caccccagcc tctgctgcaa accctaccca gaatatttcc gctctgcacc cttccctgaa
     2281 gtgagcatcc cctgttttat aagtgaagct atttttttag ggaaaaagag cgtttgttca
     2341 cgcacttgct gccaacttct ggatggcagc cttggcgtac cccacacgaa gttccttcat
     2401 ttccagtgag ggtgcttggg gcctgcccca gggaagggga ggctggggcc ctagagggac
     2461 cagtctccac aagtagggag aagccagcaa caagggaatt ctgaagttct gaacactgag
     2521 gaggggaacc aaagccactt agggcgcaga aaatgtctta tgctcgctcc cgtgtcacag
     2581 tgcagccagc actccgccct gatccaccct gagctcttcc gtggcccggc ctgtgggccc
     2641 aagaggggcc agggacaccc ccagaacagc cggtgctcgt tcctcccctc cccctcccaa
     2701 caccacccga ctctacctca gacatgaggc tcctcccacc cttgtgcacc tgtcgtctgt
     2761 gatgcatgcc gtccgttaga actgtatttc acattcctta ataaaggaca gcagtggaaa
     2821 gagaaaa
//
