LOCUS       NM_001398868            3034 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus beclin 2 (Becn2), transcript variant 2, mRNA.
ACCESSION   NM_001398868 XM_039091438
VERSION     NM_001398868.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3034)
  AUTHORS   He,C., Wei,Y., Sun,K., Li,B., Dong,X., Zou,Z., Liu,Y., Kinch,L.N.,
            Khan,S., Sinha,S., Xavier,R.J., Grishin,N.V., Xiao,G.,
            Eskelinen,E.L., Scherer,P.E., Whistler,J.L. and Levine,B.
  TITLE     Beclin 2 functions in autophagy, degradation of G protein-coupled
            receptors, and metabolism
  JOURNAL   Cell 154 (5), 1085-1099 (2013)
   PUBMED   23954414
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Dec 27, 2021 this sequence version replaced XM_039091438.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2798              JAXUCZ010000013.1  90375186-90377983
            2799-3034           JAXUCZ010000013.1  90424298-90424533
FEATURES             Location/Qualifiers
     source          1..3034
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..3034
                     /gene="Becn2"
                     /gene_synonym="RGD1563293"
                     /note="beclin 2"
                     /db_xref="GeneID:289269"
                     /db_xref="RGD:1563293"
     exon            1..2798
                     /gene="Becn2"
                     /gene_synonym="RGD1563293"
                     /inference="alignment:Splign:2.1.0"
     CDS             1552..2838
                     /gene="Becn2"
                     /gene_synonym="RGD1563293"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="beclin-2 isoform 2"
                     /protein_id="NP_001385797.1"
                     /db_xref="GeneID:289269"
                     /db_xref="RGD:1563293"
                     /translation="MSPALFLCHRCNEPLKLLQQQGGPLEVQHHANLPTEMPVSGQSR
                     VRTSHRAHSDGGRTCQGGACCTFTLLGESVSVRTLHTVQNTTIEIFEILSEQKVVDHP
                     LCVDCTDNLLVQLDDQLTLVASDNQSYQGFLERQSLVSEEETEALHAELRAELSGLEQ
                     EEARLVQELEDLDGHHARVAAELRAAQAESKELYQQNEEHRASYSVLKMEQLELTDQL
                     SSVENQLQYALGQLCHLRKTSIFDATFTISDDGPLGMINNFRLGCLPAVRVGWTEINA
                     AWGQTALLLFSLSKMAGLQFQRYQLVPLGDHSYLKSLTADEVLPLFSDGNHSVFLNNT
                     FDCAMKAFLDCLQQFVEETEKDERYPCLPYRIHPLEGVMEDIGDSGDCCPIRTHLNTE
                     EEWSRALKFMLADLKLIVAWASSSSTSFYKQIEIPR"
     exon            2799..3034
                     /gene="Becn2"
                     /gene_synonym="RGD1563293"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaggtcaga agggttaata gaactgataa ttcttgcccc ccccccgttc tcttattaag
       61 gaattcatta attttgaggt ccactcttaa tatgtagccc aggctggcct tcaattcaca
      121 gtcctcccac cttagcttct gaagtatatg ggattacagt gttgactggt gttttagtcc
      181 atggctaaac tgatggtaaa aagcacaact ccaggctatt tttgtttcat gaattgaatg
      241 agaatatttc ccatgaatgc ctgtcatagt actgtgtggt agaggatgct gactgtattg
      301 tgaaagcagt ctgattctgt acgtcagaca aggcttcctg gaggagatgc ctctgtaagg
      361 aaaggtcctt gcctctaagc tgatgccttg agttcaatcc ctggaaaccc ccctggtaga
      421 agataaccaa ctcttttttt tttttttttt tttttagatt tcttcagaca caccagaaga
      481 gggcatcgga tccaattaca gatggttgtg agccaccatg tggctgggaa ttgaactcag
      541 gacctctgga agagcagtcg gtgctcttaa ccactgagcc atctctccag cccaagataa
      601 ccaactcttg aaagatgtct tctgacttct acttgatgtt ccctccataa taaatatatt
      661 ttaaaatcct gattttaaaa gggaattgag agcaatttgg gtggtgggaa gtatgactca
      721 ctggtgaact aaaatcaagt catgtggaga ggcaggaaga gaggctggca gtctggacct
      781 tggagttggg ttgatatgac tggcttcttg ttgagtttat attttgagat agggcagctt
      841 agaacccagg ctgggcttaa actcctgatc cttctgcctc tactctccaa gtgctaatac
      901 aggcacttgt gtctttttgt ttttcatttt tgtcacagtc tccctgaacc tggatcgtct
      961 gttactctgg agctaaagct ggtaacaatg ctaggatcac agggatgtgt caatacacct
     1021 ggacttttct tttttctttt agggcagggt ctcagtatgc actccaggtc ctccgggtac
     1081 tgtatagttt aggcagacga caaattcaac gttcagtggg tgtggcgata taaatcttta
     1141 atcccgtcgc ctgggaggca gaggcaagtg aaggtcaggc agacctagag agttcaaact
     1201 ctacctcaaa tatacataaa tgaacaaatt caaggtctcg cctctatacc tcgaatgtta
     1261 ggattccagg catgtgccat tatacccagt ttagactttt tctaaagatg acggtaaacg
     1321 caaaaagtgt tttaaggtta taaatagttt aaggtgtgtc ttaaaaactt tcaaggagaa
     1381 aaacaagata agcagcattt cctctttttt tccagagagc ctctggcccg aaggatgcta
     1441 taggtcaaca ggtagcccaa taggggggtg tgataaggta aagagggaag gtcggttccc
     1501 aaatatgcta aagaaagaaa cctagctccg gtgggagtgt ggagctccag gatgtctccc
     1561 gccctcttcc tgtgccatcg ctgcaatgag cccctgaaac tcttacagca gcaggggggg
     1621 cccttggaag tccagcacca tgccaatctc cccacagaga tgccagtttc tggacagtcc
     1681 cgggtcagga cctctcacag agcccactct gacggtggca ggacgtgcca gggaggtgcc
     1741 tgctgcacct ttactctgct tggtgagtct gtctccgtga gaactttgca cactgtccaa
     1801 aataccacca tagagatctt cgaaatcctc tcggaacaaa aggtggtgga ccacccgctg
     1861 tgcgtggact gtaccgacaa tcttctggtg caactagacg accaactcac tctcgttgca
     1921 tctgacaacc agagctacca aggtttcctg gagagacagt cgctggtgag tgaggaggag
     1981 acggaggcgc tacacgcgga gctacgtgct gaactgtcgg gtctggagca ggaggaggca
     2041 aggctggtgc aggagctaga agacctagat ggccatcatg caagggtagc cgccgaactc
     2101 agagcagccc aggccgagag caaggagctg tatcaacaga atgaagagca cagggccagc
     2161 tattctgttt tgaagatgga acagctggag ctgacggacc agctgagcag tgtggagaac
     2221 cagctgcagt acgccctggg tcagctgtgc cacttaagaa agaccagcat cttcgacgcc
     2281 acatttacca tttcagatga cggtcccctg ggcatgatca acaatttcag gctgggctgc
     2341 ctccccgcgg tccgggtggg gtggactgag atcaatgccg cctggggaca gacagcctta
     2401 ctgctcttca gcttgtccaa gatggccggc ctgcagttcc agaggtatca gttggtgccc
     2461 ttgggggacc attcctatct caagtccttg actgctgatg aggtgctgcc gctgttctcc
     2521 gatgggaacc acagcgtctt cttgaataac acgtttgact gtgcgatgaa ggccttcctg
     2581 gactgtctgc agcagtttgt ggaggagact gagaaggacg agcgataccc ctgcctgccc
     2641 tacaggatcc atccgctgga aggggtgatg gaggacatcg gagacagcgg ggactgctgc
     2701 cccatcagga cccatctgaa cacagaggag gagtggtcga gggctctgaa gttcatgctt
     2761 gccgacctga agttgattgt tgcttgggct tcctcaagtt ctacaagttt ctacaagcaa
     2821 atagaaatcc cacgctaaag gaatccagat cactcgagaa gagcgacagg tcagtgggat
     2881 acgagcctct gcccatccca tgctcaatga gatactcctg acaagccagt aatggtgcgt
     2941 taataaaaca cccctttcaa agagtaagat caatcaacag aatgtgatcg aagggtgtca
     3001 gagtctcaga taaagcagag cagattccag ggac
//
