LOCUS       NP_001385797             428 aa            linear   ROD 27-MAR-2024
DEFINITION  beclin-2 isoform 2 [Rattus norvegicus].
ACCESSION   NP_001385797 XP_038947366
VERSION     NP_001385797.1
DBSOURCE    REFSEQ: accession NM_001398868.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 428)
  AUTHORS   He,C., Wei,Y., Sun,K., Li,B., Dong,X., Zou,Z., Liu,Y., Kinch,L.N.,
            Khan,S., Sinha,S., Xavier,R.J., Grishin,N.V., Xiao,G.,
            Eskelinen,E.L., Scherer,P.E., Whistler,J.L. and Levine,B.
  TITLE     Beclin 2 functions in autophagy, degradation of G protein-coupled
            receptors, and metabolism
  JOURNAL   Cell 154 (5), 1085-1099 (2013)
   PUBMED   23954414
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Dec 27, 2021 this sequence version replaced XP_038947366.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     Protein         1..428
                     /product="beclin-2 isoform 2"
                     /calculated_mol_wt=47926
     Region          102..232
                     /region_name="APG6_N"
                     /note="Apg6 coiled-coil region; pfam17675"
                     /db_xref="CDD:465452"
     Region          238..415
                     /region_name="APG6"
                     /note="Apg6 BARA domain; pfam04111"
                     /db_xref="CDD:461178"
     CDS             1..428
                     /gene="Becn2"
                     /gene_synonym="RGD1563293"
                     /coded_by="NM_001398868.1:1552..2838"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:289269"
                     /db_xref="RGD:1563293"
ORIGIN      
        1 mspalflchr cneplkllqq qggplevqhh anlptempvs gqsrvrtshr ahsdggrtcq
       61 ggacctftll gesvsvrtlh tvqnttieif eilseqkvvd hplcvdctdn llvqlddqlt
      121 lvasdnqsyq gflerqslvs eeetealhae lraelsgleq eearlvqele dldghharva
      181 aelraaqaes kelyqqneeh rasysvlkme qleltdqlss venqlqyalg qlchlrktsi
      241 fdatftisdd gplgminnfr lgclpavrvg wteinaawgq talllfslsk maglqfqryq
      301 lvplgdhsyl ksltadevlp lfsdgnhsvf lnntfdcamk afldclqqfv eetekderyp
      361 clpyrihple gvmedigdsg dccpirthln teeewsralk fmladlkliv awasssstsf
      421 ykqieipr
//
