LOCUS       NM_001402161           10277 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus BDP1 general transcription factor IIIB subunit
            (Bdp1), transcript variant 1, mRNA.
ACCESSION   NM_001402161
VERSION     NM_001402161.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 10277)
  AUTHORS   Vannini,A.
  TITLE     A structural perspective on RNA polymerase I and RNA polymerase III
            transcription machineries
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 258-264 (2013)
   PUBMED   23031840
  REMARK    Review article
REFERENCE   2  (bases 1 to 10277)
  AUTHORS   Dumay-Odelot,H., Durrieu-Gaillard,S., Da Silva,D., Roeder,R.G. and
            Teichmann,M.
  TITLE     Cell growth- and differentiation-dependent regulation of RNA
            polymerase III transcription
  JOURNAL   Cell Cycle 9 (18), 3687-3699 (2010)
   PUBMED   20890107
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-444               JAXUCZ010000002.1  33203798-33204241   c
            445-724             JAXUCZ010000002.1  33199859-33200138   c
            725-834             JAXUCZ010000002.1  33198336-33198445   c
            835-894             JAXUCZ010000002.1  33197350-33197409   c
            895-1023            JAXUCZ010000002.1  33193690-33193818   c
            1024-1157           JAXUCZ010000002.1  33191723-33191856   c
            1158-1252           JAXUCZ010000002.1  33189203-33189297   c
            1253-1307           JAXUCZ010000002.1  33183967-33184021   c
            1308-1448           JAXUCZ010000002.1  33178008-33178148   c
            1449-1739           JAXUCZ010000002.1  33177173-33177463   c
            1740-1878           JAXUCZ010000002.1  33174723-33174861   c
            1879-2076           JAXUCZ010000002.1  33173597-33173794   c
            2077-2236           JAXUCZ010000002.1  33168358-33168517   c
            2237-2328           JAXUCZ010000002.1  33166411-33166502   c
            2329-2518           JAXUCZ010000002.1  33164827-33165016   c
            2519-2649           JAXUCZ010000002.1  33163346-33163476   c
            2650-3859           JAXUCZ010000002.1  33156063-33157272   c
            3860-4032           JAXUCZ010000002.1  33155254-33155426   c
            4033-4255           JAXUCZ010000002.1  33154495-33154717   c
            4256-4437           JAXUCZ010000002.1  33152610-33152791   c
            4438-4645           JAXUCZ010000002.1  33151326-33151533   c
            4646-4791           JAXUCZ010000002.1  33149164-33149309   c
            4792-4999           JAXUCZ010000002.1  33147217-33147424   c
            5000-5184           JAXUCZ010000002.1  33146805-33146989   c
            5185-5572           JAXUCZ010000002.1  33145649-33146036   c
            5573-5695           JAXUCZ010000002.1  33142779-33142901   c
            5696-5732           JAXUCZ010000002.1  33141161-33141197   c
            5733-5825           JAXUCZ010000002.1  33140633-33140725   c
            5826-6051           JAXUCZ010000002.1  33139086-33139311   c
            6052-6212           JAXUCZ010000002.1  33138440-33138600   c
            6213-6363           JAXUCZ010000002.1  33134810-33134960   c
            6364-6541           JAXUCZ010000002.1  33134445-33134622   c
            6542-6602           JAXUCZ010000002.1  33131837-33131897   c
            6603-6789           JAXUCZ010000002.1  33131208-33131394   c
            6790-6994           JAXUCZ010000002.1  33125604-33125808   c
            6995-7031           JAXUCZ010000002.1  33122429-33122465   c
            7032-7299           JAXUCZ010000002.1  33120610-33120877   c
            7300-7555           JAXUCZ010000002.1  33118970-33119225   c
            7556-10277          JAXUCZ010000002.1  33112518-33115239   c
FEATURES             Location/Qualifiers
     source          1..10277
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q12"
     gene            1..10277
                     /gene="Bdp1"
                     /note="BDP1 general transcription factor IIIB subunit"
                     /db_xref="GeneID:294687"
                     /db_xref="RGD:1308512"
     exon            1..444
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..7690
                     /gene="Bdp1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     transcription factor TFIIIB component B'' homolog; B
                     double prime 1, subunit of RNA polymerase III
                     transcription initiation factor IIIB"
                     /codon_start=1
                     /product="transcription factor TFIIIB component B''
                     homolog isoform 1"
                     /protein_id="NP_001389090.1"
                     /db_xref="GeneID:294687"
                     /db_xref="RGD:1308512"
                     /translation="MFRRARLSVKPNVRPGVGTRGSAAPNPQRGPEAPRPPEPATGSA
                     PKPAEPTDVPAVDSGGAEPQEQAPGSSNNEKTGDGSNVEESSTLPSAASQRRKRVSGT
                     SSLGQPPVSAPSQSRPLSTVNHDAPQPNPTPAKEKQPCSDRYRIYKARKLREMLKEEL
                     RKEKKQWKNKFATNESQRPPDRSKMTMRDFIYYLPDSNPMTSSVEQEKKCEKSLAPTP
                     TREQENQSTQDANDNEDVEEEVDDGPLLVPRVKVAEDGSIILDEESLTVEVLRTKGPC
                     VVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHR
                     ARIEIKNKFKREEKTNGWRIDKAFQEKRPFDFDFFAHLLQKVLAEEEKRKQKSTKCQN
                     VKEKAPKPRKNAKAKTVNREEVNDDPDESVNSDTADPERPQKDARTVREEQLPSSSAQ
                     HLHLAVLEQEQEQEQSQDKRRRNQGKANKREATTVLESVLDHSSPPAAEIHKSTCPSE
                     ENENECNKEQTPSFTQNTEDIAGLASCEETLMRMDPSPSTCNHQDIMPLASESSEPCA
                     ADLPVSEPGGAVSGDVNNAEPGGAVSGDVNNAESGCAGAGSADLKTKSPETEQTDSVK
                     PKSRSRLQRPKPNLSRPVGKKSVVSQDRQDGSNKDSPSETAATKNHMEKERVTESENF
                     VTENTERESPSAGTVSDLSEKSSAQEDSQTKVLRPTRLMRSRMQRPKPNVVKAAERKQ
                     ILTSQEKVGSHVEKIEDDSCVVVPPQMGNESHKNLQCEGAASEPEQKDPVESLQSEQP
                     RALSECPSIQEDNKGNKLKQAPIVRTRFQKPKPNTGRRRRRRRSSKEGIPVDMPVSGD
                     LTATREEIPRPDTSPREEVPSVPLAPLTATASTMELESGVKDSSRNDTASNVKMPEMA
                     DVTMEIDTGLETTGRDTCPGEMEAEMIDIPMETEASLKASLNETPPMEKMPELIDNTG
                     EICTNLGETARKEIFLQENGSKEVSPVSEPETGLQETGKKLAVKESTSDMMDGTEERE
                     ADSEETERQEISAPVKEAEEAKARGEVDSPLEEIGGETSQQAIAAGAPVEQSASEEDL
                     GDSAGVEEVEVESTVGGKELKLKDAGEGHVSLMVVVSGEKTAIEETIGHLKEKERESS
                     VPWERRSGEIDVGEEMVADLEKTEKVDVSPRDSEPEEQTSGQPEAEVIPSRSDGSTGP
                     PQDRENISNKISVIPTLLEEKETTDKEVSSHGESSSQNSGHHVADQGTQLLDVQEQFS
                     DTNLSKPLPQEQKPLQVKPAPFLRSRFKKPKPNLSRAALKRATLEAEHCVPGKKPEAY
                     KMETVVLQQDRDQAASFSSPHNVPSLMASRENEKSGHEEEEEAVVLPCTQIEKDPSPP
                     NSCEPKEDSQLTQNQEDSLVSPIGTPTVNMVPQETKPNVVQTTLPVRGRLQRPRPNVQ
                     KARQRQTVEKGKAEGITKNEGPELQKDEAKTCLTVANSSGVESEVAVEVSSRVSEFKV
                     NESQGHVVPVENLSINKTSVLREQIRHENKPYVPSPALLIRRRFQKAKPNLGGARHKD
                     EQPGVEKGPTSENTALTTEDHLLQKGDCDTQLSVQAREKTEMPLEVSMRKDCVHSEES
                     GSDRNDAQLKAGPSGGAREEIAQEPTFSSSLEEQSLSKQISRPQLLKESSYSKTVPPR
                     RTTVPSASECEIDHSGKRAHRKMKASVTKARGSKRIRGKTAKKEPRASKSVLVTLRAS
                     QKDDEDDAEDFESDYEEETCHLAPEELNKAPVFVPVGLRSPEPVSAQIEETMEELEIT
                     MDGADLGCLTVVDHQLSHVDIAARDEQPEKAVYPSSFEVVIGEQPQEEPGPGDGSTEA
                     AITLLTMGDIVLQSEIIPGQGDVGVCVFPDDHSKDKNHVPFIPDNVNQKTVHDYQEVC
                     SPVISMSHVSFEDNKIVLEEQSIREAAVLGEAMEEPLSTRDTACTMSTPLRMESMLVT
                     PKAGSERILEISEPDGHQEVASLCMTKGTEVEIQRETEENDSTAVELDDKSLEPVPAA
                     ETKEQEQLLCVHGVEGARVSQEAILPARTEEHEDDLQGLQTLGAAVASSEIGQHTLES
                     GQSLGDSVAEEALRESPEGSVVPMLHVPESVPSNIPEAQHENISPQDDTVNLFANVQQ
                     DGEDEQAFILTLVEIPTNTTEGFTDASMHLMPSSLLPAPILVRSGNAVERVDLSGSLQ
                     ASSVVQDVTCSSPSRSGDSEKPPAIVELTSRKRFCCSPDESIHVPPAKKSSIAPGIDY
                     QNCTSGVCSEELNVFEKTEESCMGQGIFPTSESTHATSKPQKEHSEQTSQNTGSSGSL
                     GEIKDACVENTMTELPQSEVVSDKEEKTDPASNSKQRDSVTSSSKPPLTRPGRRPLGF
                     LSLICPKNSLESDEVTQTHSKKRLKPHIPVSRRNLKKPNPLHASQKKNQESSDPLPPP
                     SVTETVSDNTGSSESSAAEVSSDQPLVEEEKCKNGPKGASEEEVTTVSEFVFSDIFIE
                     VDETE"
     exon            445..724
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            725..834
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            835..894
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1023
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1157
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1252
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1307
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..1448
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1739
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1740..1878
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2076
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2077..2236
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2237..2328
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2329..2518
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..2649
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2650..3859
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3860..4032
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            4033..4255
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            4256..4437
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            4438..4645
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            4646..4791
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            4792..4999
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            5000..5184
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            5185..5572
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            5573..5695
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            5696..5732
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            5733..5825
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            5826..6051
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            6052..6212
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            6213..6363
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            6364..6541
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            6542..6602
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            6603..6789
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            6790..6994
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            6995..7031
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            7032..7299
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            7300..7555
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
     exon            7556..10277
                     /gene="Bdp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgagccggg acgcggggag gagaaactta gcttttagtg tggcagggtc atgaagagaa
       61 ggcggtggcg ggagagcgga ggaggcggag ggggcgcgaa actgcggtag ctggcgctgg
      121 gctggtggtt ttggctgggt gggagggcga gagtcccagc cctcgggcag cggcaggggc
      181 tctgggctga gcgcggccgt ggagccgccg ctctcggtcc cctggctccg ccatgttccg
      241 cagggcacgc cttagcgtga agccgaatgt caggcctggt gtaggcacca ggggctccgc
      301 cgctcccaat ccccaacgtg gaccggaggc acctaggcct cccgagcctg ccaccgggtc
      361 tgctccgaag ccagcggagc ccacagatgt gcctgcggtc gattccgggg gagcggaacc
      421 ccaagaacag gctcccggga gcagtaataa tgaaaagact ggtgatggaa gtaatgttga
      481 agagtctagc acactgccct ctgctgcttc acagagaaga aagcgagtgt ctggcacgtc
      541 tagtcttggt cagcctcctg tcagtgcccc ctcacagagt cgccccttat ctacagttaa
      601 tcacgatgcg ccacagccaa accctactcc agctaaagag aaacagccgt gctcagacag
      661 ataccgaata tataaagccc gcaaactgag agagatgttg aaagaggagc tgagaaagga
      721 gaagaaacag tggaaaaaca aatttgcaac aaatgaaagc cagagaccac cagatcgttc
      781 aaaaatgact atgagagact tcatatatta ccttccagat agcaatccga tgacttcttc
      841 agtggaacaa gaaaagaaat gtgagaaatc cttggctccc accccaacaa gagagcaaga
      901 aaatcagagc acgcaagatg ctaatgataa tgaagatgtg gaagaggagg tggatgacgg
      961 gccacttctg gttcctcgag taaaagtggc agaagatggc tctattattt tagatgaaga
     1021 aagtttaact gtagaagttt tgagaacgaa aggcccctgt gttgttgagg agaatgatcc
     1081 tatatttgag cgtggctcca caactactta ttccagcttt aggaaaaact actactcaaa
     1141 gccgtggtcc aataaagaaa cagatatgtt ttttttagcc atcagcatgg taggaactga
     1201 cttttctatg attggacaac tttttcctca cagagcaagg atagaaatta agaataaatt
     1261 taaacgtgaa gaaaaaacaa atggatggag aatagacaaa gccttccagg aaaaacgccc
     1321 ttttgacttc gatttttttg ctcatttgct tcagaaagtt cttgctgaag aagaaaaaag
     1381 aaaacaaaaa tctactaaat gtcagaatgt aaaggaaaag gcccccaaac cacggaaaaa
     1441 tgcgaaagca aaaacagtaa acagggaaga agtgaatgat gaccctgatg agtctgtgaa
     1501 cagtgatact gcagatccag aaagacctca gaaggacgcc cggacagtcc gtgaggagca
     1561 actgccaagt tcatcagcac agcacctaca ccttgctgtg ctagagcaag agcaagagca
     1621 agagcaaagc caagacaaga ggaggaggaa ccaaggcaaa gccaataaac gggaagcaac
     1681 aactgtttta gagagcgttc ttgatcattc gagccctcct gcagcagaaa tacacaagag
     1741 tacgtgtcct tctgaggaaa atgaaaatga gtgcaataaa gaacagaccc cttcctttac
     1801 acagaacaca gaggacattg caggtttagc atcctgtgag gagacgttga tgagaatgga
     1861 ccccagccct tccacatgta atcaccaaga catcatgcca ctagcaagtg agtcctcaga
     1921 gccgtgtgct gcggatttac ctgtgtcaga acctggaggt gctgtctctg gtgatgtgaa
     1981 taatgctgaa cctggaggtg ctgtctctgg tgatgtgaat aatgctgaga gtggctgtgc
     2041 aggagcagga agtgcggatc tgaagactaa gtcaccagaa actgaacaga cagacagtgt
     2101 caaaccaaaa tcaagaagtc gactccagag acctaagcct aacttgtccc ggccagttgg
     2161 gaagaagtca gttgtttcac aagacagaca agatggaagc aacaaggact caccttcaga
     2221 aactgcagcc acgaagaatc acatggaaaa ggagagagtg actgaatctg aaaattttgt
     2281 aacagagaat acagagagag agagcccaag tgccggaact gtgtctgatt tgagtgaaaa
     2341 gtcctccgcc caggaggata gtcagacaaa ggtcttaaga cctacccggc tgatgaggag
     2401 tagaatgcaa agaccaaagc caaatgtagt gaaagctgca gaaagaaaac aaattctcac
     2461 ctcacaggaa aaagttgggt cccatgtaga gaaaattgaa gatgactcgt gtgtagtggt
     2521 tcctccacaa atgggaaatg agtcacacaa aaacttgcag tgtgaaggcg ctgcgtcaga
     2581 acctgaacaa aaggaccctg tggaaagtct gcagtctgag caacccaggg ctctcagtga
     2641 gtgtccgagt attcaagaag ataataaagg aaataagctg aaacaagccc caattgtaag
     2701 gacaagattt cagaaaccaa aaccaaatac aggaagaaga agaagaagaa gaagatcctc
     2761 caaggaaggg ataccagtgg acatgcctgt ttctggagac ctaacagcaa cccgggaaga
     2821 aattccgcga ccagacactt ccccgaggga ggaggtaccg agtgtacctc tcgcccctct
     2881 cactgccacc gcttccacca tggaattgga gtcaggtgtg aaagatagta gcagaaatga
     2941 cacagcttct aatgtgaaga tgccagaaat ggcggatgtc actatggaaa tagatacagg
     3001 tttggaaaca actggaagag atacttgccc aggggagatg gaggcagaaa tgattgacat
     3061 ccctatggaa acagaggcaa gcttgaaagc atctttaaat gagactcctc ctatggagaa
     3121 gatgccagag ctgattgata acactgggga aatttgcacg aatttgggag aaactgcaag
     3181 aaaagaaata tttttacagg aaaatggttc caaggaggtc agtccagtta gtgaaccaga
     3241 gacaggtttg caagaaactg gaaaaaagtt ggccgtgaaa gagagcacat cagatatgat
     3301 ggatggcact gaagaaagag aggcagattc agaggaaact gaaagacaag aaatatctgc
     3361 cccagtaaag gaagcagagg aggccaaagc caggggtgaa gtggactcac ccctggaaga
     3421 gattggagga gaaacttccc agcaagcaat agcagcaggc gctcctgtgg agcagtcggc
     3481 cagtgaggag gacctaggtg acagcgcagg cgtcgaggag gtggaagtgg agagcactgt
     3541 aggaggaaag gagctcaagc tgaaggacgc tggagaagga cacgtctcct tgatggtcgt
     3601 ggtctcggga gagaagactg ccattgagga aacgattgga catttgaaag aaaaagaaag
     3661 agagagttct gtcccttggg agagaagatc tggagagatc gatgttgggg aagaaatggt
     3721 ggcagactta gaaaaaacag aaaaagtaga cgtttctcca agagacagtg aaccagagga
     3781 acagacctca gggcagcctg aggcagaagt aattccaagc aggagtgacg gcagcactgg
     3841 gcctccacag gatagagaaa atattagcaa taaaatctca gtgataccta cactcttgga
     3901 agaaaaagaa acaactgata aggaggtatc cagtcatggg gagtcttctt cacagaattc
     3961 tggacaccat gtagcagacc aagggacaca gcttctagat gttcaagagc agttttcaga
     4021 tactaattta agcaaacctc ttcctcaaga acagaagcca cttcaagtta aaccagctcc
     4081 ttttctgaga agtcgattca aaaaaccaaa gccaaacttg tcaagagcag ctttaaagag
     4141 agcaacccta gaagcagaac attgtgtacc tgggaagaaa ccagaagcat acaaaatgga
     4201 gactgtcgtg ttgcagcagg acagagacca agctgcttct ttctcttctc cacataatgt
     4261 accttcccta atggcgtcaa gagaaaatga gaaatcaggt catgaggagg aggaggaggc
     4321 tgtggtactg ccatgtacac agattgaaaa agatccttca ccgccaaatt catgtgaacc
     4381 taaggaggat tctcagttaa cccaaaacca ggaagacagc ttagtttctc ctattgggac
     4441 tccgacagtg aatatggtcc cacaagaaac aaagccaaat gtcgtccaaa cgactctacc
     4501 agtgaggggt cgacttcaga gaccaaggcc aaatgtgcaa aaggccagac agagacaaac
     4561 agtagaaaag ggcaaagcgg aaggcataac taagaatgaa ggaccagaac tgcaaaaaga
     4621 tgaagctaaa acatgcctga ctgtggcaaa ttcttctgga gttgaaagtg aagttgcagt
     4681 tgaagtgtcc tccagagttt cagagttcaa agtgaatgaa agccaaggcc acgtggttcc
     4741 tgtagaaaac ttaagtatta acaaaaccag tgttctacgt gaacagatcc ggcatgaaaa
     4801 taaaccatat gttcctagtc cagcactgct gataagaagg cggttccaaa aggctaaacc
     4861 aaatttagga ggagcacggc ataaagatga gcagccaggt gtagagaaag gcccaaccag
     4921 tgagaacaca gcactaacaa cagaagatca cctgctacag aagggagact gtgataccca
     4981 gctttctgta caagctaggg aaaagacaga aatgcctctg gaggtttcca tgaggaaaga
     5041 ttgcgtacat tctgaagagt cgggctctga cagaaatgac gctcagctaa aagctggacc
     5101 atcaggaggt gccagggaag agattgccca ggagcctaca ttttcttcga gcctcgaaga
     5161 gcagagtctc agtaaacaaa ttagccgtcc acaactattg aaagaatcaa gctattccaa
     5221 aactgttcct cctcgaagaa caactgtccc ttctgcctct gagtgtgaga tagatcatag
     5281 tgggaaaaga gcgcatcgga agatgaaagc aagtgtgacc aaagcacgcg gatcaaaacg
     5341 aattcgaggt aagactgcta agaaggaacc tagagcttcc aagtccgtgt tggtgactct
     5401 tcgggcttct cagaaagacg atgaagatga tgctgaggat tttgagtctg actatgagga
     5461 agaaacctgt catcttgccc cagaagaatt aaacaaagca ccagtgtttg tacctgttgg
     5521 tctcagatcc cctgaaccag tttctgctca gatcgaggaa acaatggaag agcttgagat
     5581 caccatggac ggtgcagacc taggatgttt gactgtggtt gaccatcagc tttcacatgt
     5641 ggacatagca gctcgggacg agcaaccaga gaaggctgtg tacccgtcct catttgaagt
     5701 ggtcataggt gaacagcccc aagaagaacc aggtcccggt gatgggagca ctgaagccgc
     5761 cataactcta cttacaatgg gagacatagt actgcagtca gagatcattc ctggacaggg
     5821 tgatgtagga gtatgtgtat ttcctgatga tcattcaaag gataagaatc atgttccttt
     5881 tatcccagat aatgtaaatc agaaaactgt tcatgactat caggaggtgt gctcacctgt
     5941 cattagtatg tcgcatgtgt catttgaaga caacaagatt gtactggagg aacaaagcat
     6001 cagagaagct gccgtgctag gagaagccat ggaggagcct ctgtcaacca gggatacagc
     6061 ttgtacaatg agtaccccct tgagaatgga gagtatgctt gttacaccaa aagcaggttc
     6121 tgagagaatt ttagagatca gtgagcctga tggtcatcag gaagttgcca gtctttgcat
     6181 gactaaaggg acagaagtgg aaattcaaag agaaacggag gaaaatgatt ccacagctgt
     6241 agaattagac gacaaaagcc ttgagccagt tccagcagca gagaccaagg agcaggagca
     6301 gctgctgtgc gttcatggtg tcgaaggggc cagggtttct caagaagcaa tcctacctgc
     6361 aagaactgaa gagcacgagg acgacttgca agggcttcaa acgttgggcg ctgcagttgc
     6421 ttcgtctgag atagggcagc acacacttga gtcaggtcag agtcttggtg acagtgttgc
     6481 tgaagaagcc ctcagagaaa gccctgaagg cagcgttgtg cccatgcttc atgtgccaga
     6541 gagtgtacca tctaatattc cagaagccca acacgaaaac atcagtcctc aagatgatac
     6601 agtgaatctg tttgctaatg ttcagcaaga tggagaagat gaacaagcat tcattttgac
     6661 cttggtggag atcccaacta acacaacaga aggatttacc gacgcctcca tgcacttaat
     6721 gccgagctct ctgctgccag cacctatatt ggtcagatct gggaatgcag tagaaagagt
     6781 tgacctgagt gggagtttac aagcctcttc ggttgttcag gatgttacgt gctcgtctcc
     6841 ttctagaagt ggcgattctg aaaagcctcc tgctattgtg gagcttacat ctaggaagag
     6901 gttttgttgc agtcctgatg aaagtattca tgttcctcct gccaaaaagt cctcaattgc
     6961 tccaggaatt gattatcaaa actgtacctc tggggtatgt tcagaggaat taaatgtttt
     7021 tgagaaaaca gaggagtctt gcatgggaca aggcattttc cctacctcag agagcacaca
     7081 tgcaacctca aaacctcaaa aggaacacag tgaacaaacg tctcagaata cagggtcatc
     7141 tgggtctctt ggtgaaataa aagatgcatg tgtagaaaac accatgactg aactgcctca
     7201 gagtgaggta gtatctgata aagaagagaa aacggatcct gcttccaatt ctaaacagag
     7261 ggacagcgtg acgtcatctt caaaaccccc tctgaccaga cctggcagaa ggcctttggg
     7321 atttttatca ttaatatgtc caaaaaatag tttggaatct gatgaagtga ctcaaaccca
     7381 tagtaagaag cgactaaagc ctcatatacc tgtatcacga cgaaatttga aaaaacctaa
     7441 tccacttcat gcaagccaga aaaaaaatca agaatcttca gatccactcc caccaccaag
     7501 tgtgactgaa actgtctctg ataacactgg aagttctgaa agctcagcag ctgaggtttc
     7561 ttctgatcag ccattggtag aagaagaaaa atgtaaaaat gggccaaaag gagcatctga
     7621 agaagaggtg accacagtct cagagttcgt cttcagtgac atcttcattg aagtggatga
     7681 aacagaataa agctctctcc tggggtttcc ccttcttttt actttctata tttttgtaat
     7741 gagtttgaaa tttccagcga ccctgacttt aacaaagcag tgtttagaga agcaccactg
     7801 cctattttta tttaggtcaa ttttgaatat ttattgagct tcatttgaag cttttataat
     7861 cagtgggaaa catttcattc tgattgactt tgcgttttgg aagtaccagg caatgacgac
     7921 tggtgtcacc gacaggcact gcagcttgtt tacatttgat gccctgtgag agcacacgct
     7981 gacgtgagaa cggtgtgcat acatccgtat aaaatcatag tgctgacata cttggagctc
     8041 gattatattt aacatttagt aacccccttt tataaaggtg gctgtgtttt ctttctgtgg
     8101 ggtttttttt tttttttggt tagtttgttt ttttcttttc tttttatttt ttctgtttct
     8161 tgagggtgat ctgttgtcta taagtatatg aaagcaaatt gtgaaactcc actttggtat
     8221 ggtaaagtta aaacttttct attatctatt tgactggaaa aaatgtgtat ttttctaatt
     8281 catggtgatg taacattagt cctgattgaa gatctagtat ttaaacttgt atttataaag
     8341 gtgacacatc aaagagatta tttattttta aattttttat ttaaaatata tcccaattta
     8401 attattttca cttaccagat gtgggtaaag aaagcattaa caaataattt gtctcctttt
     8461 cctccttact ttaaaagcta ttttaaaatg tcataattga gactgttaag gtagtgttga
     8521 tattttgaat acttttctca cactttagta tattgaattt gtactgtgaa tatttttgct
     8581 tttcttactc taatctcagg attttcattg gaagaaaaat taacctaaaa gacaaattgt
     8641 cctttataac tgaatctttt tacacacaca cacacacaca cacacacaca cacacacaca
     8701 ccccacgtcc ttaaaacagt ttagtcctac taaattttgt ccatagaaca tgtgggcctt
     8761 taaccccaga acatgattct gatgttaaag cagaaaatat gacaggaaga cttagcaaag
     8821 ccagtgatgt cctcattatg aacttgggtg ttttaaattt ttgtgtgatt catgtgtctt
     8881 gttcccctta caattttccc ctggttcaaa ttaaactctt cgaagagcaa atgtattcaa
     8941 ttttatttta aaacctcgtg cgttgatatg attgatgcat tagctcggta gttagaagtt
     9001 tctccacaaa gcattctttg tgagctgtag cccgcagggc ttcccgtgtt caagactggc
     9061 cttgcactct gtaggtgaga gtgttcttca gcttgtcctc ctccgcttgg agcacagggc
     9121 tttgcccacc tttatgcctt gctcagagaa gaagccatgg ctttcacacg ctaggcaaac
     9181 actctgccat gtggggtttc ccagccccag actacagggg gtgagaatca gaaggtgctg
     9241 gtgtctgttt gtaggagcta tttgcaaaat gtgcctaaga ttcaaaaact atgttcagtc
     9301 tgttatgaag tgagcaatac ttcagttgga aaatattttt acatctaggt aaattttcgt
     9361 ttttcatatt gataaaatgg taaccacttt tcaaatttca aagcagaaga agatagaact
     9421 caatgagtct agattgctga ctgttgaact tcctgggaca tgtttgttgt gctgtctgtg
     9481 gcttggagta aaacgtacag ttcagtgttt gttataaagg aagatctgtg agttggatga
     9541 aattctcaaa tgtatgcatc tgtttcatgt gattaatgta acaatcatgg aggtaattca
     9601 catcgctgtt tcaatgctgt ttttgttttt aaaatgtcat gttctgtaaa gttttttttt
     9661 cttttaagtg ttacttgggt tagatcaccg agactcaact attatttatc cctgtatatt
     9721 tattttttta acctctgact cattcatctg taataaactg attttatgga agatgtaatt
     9781 tattgtataa agactccagg ggtatttgtt gtaaagagaa tcaagttagt caacaaactc
     9841 tcctgctatc acagtctcaa acctgtgcag gaaggagaaa cacaatcagt gtggttagct
     9901 ttaaggcttt gggaagattt gctatggtgc acagaggttg caaggaattt gttgtagaac
     9961 tcttaaagga gacgtgtgaa aggagtttac cttctcccga ctgttttcct ctgatcattt
    10021 ataccttagc agatggctga gtcctggtta aaaagtctaa ttgttggtaa acaattaagg
    10081 caagacatag atgaaaatat taatatccaa tgtttaccac cgtattattc taaatgcaag
    10141 tgaccatgta taatatcttg cttgaagaag tttttgacaa aagaagcaat atctatcatt
    10201 tgtaagtttt cttgttctaa agaaagcagt tatgttctgt agataaaatt tatgtaaata
    10261 aaagttattt tatacca
//
