LOCUS       NM_001047852            3230 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus BCL2-associated transcription factor 1 (Bclaf1),
            mRNA.
ACCESSION   NM_001047852 XM_001055723 XM_001073455 XM_214967
VERSION     NM_001047852.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3230)
  AUTHORS   Orieux,G., Picault,L., Slembrouck,A., Roger,J.E., Guillonneau,X.,
            Sahel,J.A., Saule,S., McPherson,J.P. and Goureau,O.
  TITLE     Involvement of Bcl-2-associated transcription factor 1 in the
            differentiation of early-born retinal cells
  JOURNAL   J Neurosci 34 (4), 1530-1541 (2014)
   PUBMED   24453340
  REMARK    GeneRIF: Bclaf1 facilitates the differentiation of early retinal
            precursors into retinal ganglion cells, amacrine cells, and
            horizontal cells rather than into cone photoreceptors.
REFERENCE   2  (bases 1 to 3230)
  AUTHORS   Horiuchi,K., Kawamura,T., Iwanari,H., Ohashi,R., Naito,M.,
            Kodama,T. and Hamakubo,T.
  TITLE     Identification of Wilms' tumor 1-associating protein complex and
            its role in alternative splicing and the cell cycle
  JOURNAL   J Biol Chem 288 (46), 33292-33302 (2013)
   PUBMED   24100041
REFERENCE   3  (bases 1 to 3230)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 3230)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 3230)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   6  (bases 1 to 3230)
  AUTHORS   Liu,H., Lu,Z.G., Miki,Y. and Yoshida,K.
  TITLE     Protein kinase C delta induces transcription of the TP53 tumor
            suppressor gene by controlling death-promoting factor Btf in the
            apoptotic response to DNA damage
  JOURNAL   Mol Cell Biol 27 (24), 8480-8491 (2007)
   PUBMED   17938203
REFERENCE   7  (bases 1 to 3230)
  AUTHORS   Kasof,G.M., Goyal,L. and White,E.
  TITLE     Btf, a novel death-promoting transcriptional repressor that
            interacts with Bcl-2-related proteins
  JOURNAL   Mol Cell Biol 19 (6), 4390-4404 (1999)
   PUBMED   10330179
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC161968.1.
            
            On Aug 28, 2008 this sequence version replaced NM_001047852.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161968.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3230
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     gene            1..3230
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /note="BCL2-associated transcription factor 1"
                     /db_xref="GeneID:293017"
                     /db_xref="RGD:1309704"
     exon            1..119
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            120..223
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            224..337
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..2999
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /codon_start=1
                     /product="bcl-2-associated transcription factor 1"
                     /protein_id="NP_001041317.2"
                     /db_xref="GeneID:293017"
                     /db_xref="RGD:1309704"
                     /translation="MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS
                     RSRSRDRIYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHS
                     RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG
                     SQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSATSGDIWPGLSAY
                     DNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSV
                     GNGSSRYSPSQNSPIHHIPSRRSPAKTITPQNAPREDSRGRSSFYPDGGGDQETAKTG
                     KFLKRFTDEESRVFLLDRGNTRDKEAPKEKGSEKGRTDGDWDDQEVLDYFSDKESAKQ
                     KFHDSEGDDTEETEDYRQFRKSVLADQGKSFATSSHRNTEEEGPKYKSKVSLKGSRES
                     DGFREEKNYKLKETAYIVERPSTTKDKHKDEDKGSDRITVKKEVQSPEQVKSEKLKEL
                     FDYSPPLHKSLDAREKSIFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT
                     KDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSP
                     AVTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSALRKHTRLAGDERVFKEEIQKG
                     DKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKPYRDDS
                     KHKGREQDHSRSSSSSASPSSPSSREEKESKKEREDEFKSHHEMKDYSGFAGVSRPRG
                     TFFRIRGRGRARGVFAGTNPGPNNSNSTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDG
                     VDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKD
                     RRKEEKE"
     exon            338..1249
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1915
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2085
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2191
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2192..2276
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2277..2452
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2453..2633
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..2780
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2781..2993
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
     exon            2994..3207
                     /gene="Bclaf1"
                     /gene_synonym="Aa2-041"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagccgagct agcgcgacga ggccacctct atggtcttcc tctccttctg gagtcgggaa
       61 atggccgctg tgtagttaca gcggaggtaa atcctgagaa tcgtgcttcg gcgtgtcagg
      121 aatttgaatt tagagtttaa tttcctataa cattctctac aagaagaatc ttggcagtat
      181 cttaaagaca tcactgactt ctggatcctg tataaagccc aaggagaaaa gaaatgggcc
      241 gctccaattc tagatcacat tcttcaagat ccaagtctag atcacagtct agttctagat
      301 caagatcaag atcacattct agaaagaaga gatacagttc taggtctcgt tccagaacat
      361 attcaaggtc tcgtagtaga gatcgtattt attctagaga ttatcgtcgg gattacagga
      421 ataatagagg aatgagacga ccttatgggt acagaggaag gggtagaggg tattatcaag
      481 gaggaggagg tagatatcac cgaggtggct atagacctgt ttggaataga aggcactcta
      541 ggagtcctag gcgaggtcgg tcacggtcca ggagcccgaa aagaagatct gtgtcttctc
      601 aaagatcccg aagcagatct cgccggtcat acagatcctc taggtctcca agatcatcat
      661 catctcgttc ttcatcccct tatagcaaat ctcctgtctc taaaagacga gggtctcagg
      721 aaaaacagac caaaaaagct gaaggggaac cccaagaaga gagtcctttg aaaagcaaat
      781 cacaggagga accaaaggat acttttgaac atgatccatc tgaatctatt gatgagttta
      841 ataaatctgc tacatctggt gatatttggc ctggcctttc agcttatgat aatagtccaa
      901 ggtcacctca tagtccttca cctattgcta ccccacccag tcagagttca tcatgctcag
      961 atgcccccat gcttagtaca gtccactctg ccaaaaatac cccctctcag cactcacatt
     1021 ccattcagca cagtcctgag aggtctggat ccggttctgt tgggaatggg tctagtcgat
     1081 atagtccttc tcagaatagt ccgattcatc acatcccatc acgaagaagc cctgcaaaga
     1141 caatcacacc acagaatgct ccaagagagg actctagggg gcggtcctct ttttatcctg
     1201 acggaggagg agatcaggaa acagcaaaga caggaaagtt tttgaaaagg tttacagatg
     1261 aagagtctag agtattcctg cttgataggg gtaataccag ggataaagag gccccaaagg
     1321 agaaagggtc cgagaaaggc aggacagacg gagattggga cgatcaggag gttctagatt
     1381 actttagtga taaagagtct gcaaaacaaa agttccatga ttctgaaggg gatgacacag
     1441 aggagacaga ggattataga cagtttagga agtcagtcct ggcagatcag gggaagagct
     1501 ttgctacttc atctcaccgg aatactgagg aggaaggacc caagtacaag tccaaagttt
     1561 cactaaaagg cagtagagaa agtgatggat ttagagaaga aaaaaattat aaactgaaag
     1621 agactgcata catagtggaa aggcctagca ctacaaagga caagcacaag gacgaagaca
     1681 aaggctctga cagaataaca gtgaagaaag aagtgcagtc accggagcag gtaaagtctg
     1741 aaaagctcaa agagctcttt gattacagtc cccctctaca caagagtctg gacgcacgag
     1801 aaaagtccat cttcagagag gagagcccgc tgaggatcaa aatgatagcc agtgattctc
     1861 accgtcctga agtcaaactc aaaatggccc ctgttcctct ggatgactcc aacagacctg
     1921 cctccttgac taaagacagg ctacttgcta gcacgcttgt ccattctgtc aagaaagaac
     1981 aagaattccg atccatcttt gaccacatta agttgcctca ggccagcaaa agcacttcag
     2041 agtcatttat acaacacatt gtatccttgg ttcatcacgt gaaagagcaa tacttcaaat
     2101 cacctgcagt gaccctaaac gagcggttca cttcatacca gaaagctact gaagagcata
     2161 gtacccggca aaagagccct gagatacaca ggaggattga catctctcca agcgctctga
     2221 ggaagcatac ccgtttagca ggagacgaga gagtttttaa agaagaaatt caaaagggag
     2281 ataaaaaatt aaggtgtgat tcggctgatc ttcggcatga cattgaccgt cgccgcaaag
     2341 aaagaagtaa agagcgggga gattccaagg gttcgaggga atctagtgga tcaagaaagc
     2401 aagagaaaac accaaaggat tacaaggagt acaaacctta cagagatgac agcaaacata
     2461 aagggagaga gcaagatcat tctcggtcat cgtcctcttc agcatcgcct tcgtcaccca
     2521 gctcccgaga agagaaagag agtaagaaag aaagagaaga cgagtttaaa tctcaccatg
     2581 agatgaaaga ctactcagga tttgcaggag ttagcaggcc acgaggaacc ttttttcgga
     2641 tcagaggcag aggaagagcc cgaggcgttt ttgctgggac aaaccctggt ccaaacaact
     2701 caaactccac tttccaaaag agaccgaagg aagaggagtg ggatccagag tataccccaa
     2761 agagcaagaa gtacttcttg cacgatgaca gagatgatgg tgtggattat tgggccaaaa
     2821 gaggaagagg tcgtggtact tttcaacgcg gcagagggcg ctttaatttc aaaaaatcag
     2881 gtagcagtcc aaaatggact catgacaaat accaaggaga tgggattgtt gaggatgaag
     2941 aggagaccat ggaaaataat gaagagaaga aggataggcg caaagaagaa aaggaatagt
     3001 ctcaagattg catcagggag cagaacttga cacttaattt ttttaaacct gatttttgtt
     3061 ttcaaataag aatgtaagca ttttacttaa aatgtactgt ttgcaagtag tctatagaaa
     3121 ttttgtttta agtcttcaaa tatcttgaaa atagtagact gtatgttgaa aattgtactg
     3181 aaataaagta gaagacgttc aatatcaaaa aaaaaaaaaa aaaaaaaaaa
//
