LOCUS       NM_001106817            5711 bp    mRNA    linear   ROD 16-MAR-2025
DEFINITION  Rattus norvegicus BCL9 like (Bcl9l), transcript variant 2, mRNA.
ACCESSION   NM_001106817 XM_001062700 XM_217124
VERSION     NM_001106817.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5711)
  AUTHORS   van Tienen,L.M., Mieszczanek,J., Fiedler,M., Rutherford,T.J. and
            Bienz,M.
  TITLE     Constitutive scaffolding of multiple Wnt enhanceosome components by
            Legless/BCL9
  JOURNAL   Elife 6, e20882 (2017)
   PUBMED   28296634
  REMARK    Erratum:[Elife. 2017 Mar 30;6:e27150. doi: 10.7554/eLife.27150.
            PMID: 28358670]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5711)
  AUTHORS   Deka,J., Wiedemann,N., Anderle,P., Murphy-Seiler,F., Bultinck,J.,
            Eyckerman,S., Stehle,J.C., Andre,S., Vilain,N., Zilian,O.,
            Robine,S., Delorenzi,M., Basler,K. and Aguet,M.
  TITLE     Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell
            traits in colon epithelium and adenocarcinomas
  JOURNAL   Cancer Res 70 (16), 6619-6628 (2010)
   PUBMED   20682801
REFERENCE   3  (bases 1 to 5711)
  AUTHORS   Brack,A.S., Murphy-Seiler,F., Hanifi,J., Deka,J., Eyckerman,S.,
            Keller,C., Aguet,M. and Rando,T.A.
  TITLE     BCL9 is an essential component of canonical Wnt signaling that
            mediates the differentiation of myogenic progenitors during muscle
            regeneration
  JOURNAL   Dev Biol 335 (1), 93-105 (2009)
   PUBMED   19699733
REFERENCE   4  (bases 1 to 5711)
  AUTHORS   Fritzmann,J., Morkel,M., Besser,D., Budczies,J., Kosel,F.,
            Brembeck,F.H., Stein,U., Fichtner,I., Schlag,P.M. and Birchmeier,W.
  TITLE     A colorectal cancer expression profile that includes transforming
            growth factor beta inhibitor BAMBI predicts metastatic potential
  JOURNAL   Gastroenterology 137 (1), 165-175 (2009)
   PUBMED   19328798
REFERENCE   5  (bases 1 to 5711)
  AUTHORS   Adachi,S., Jigami,T., Yasui,T., Nakano,T., Ohwada,S., Omori,Y.,
            Sugano,S., Ohkawara,B., Shibuya,H., Nakamura,T. and Akiyama,T.
  TITLE     Role of a BCL9-related beta-catenin-binding protein, B9L, in
            tumorigenesis induced by aberrant activation of Wnt signaling
  JOURNAL   Cancer Res 64 (23), 8496-8501 (2004)
   PUBMED   15574752
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001062700.1, XM_217124.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132261, SAMD00132262
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..5711
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..5711
                     /gene="Bcl9l"
                     /note="BCL9 like"
                     /db_xref="GeneID:300673"
                     /db_xref="RGD:1309096"
     exon            1..662
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            663..719
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            720..821
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     CDS             796..5127
                     /gene="Bcl9l"
                     /note="isoform 2 is encoded by transcript variant 2;
                     B-cell CLL/lymphoma 9-like protein"
                     /codon_start=1
                     /product="B-cell CLL/lymphoma 9-like protein isoform 2"
                     /protein_id="NP_001100287.1"
                     /db_xref="GeneID:300673"
                     /db_xref="RGD:1309096"
                     /translation="MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKL
                     TNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVS
                     PFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEW
                     CSGPDSEEDDKPIGATHNCNVADPAMVAPQLGPGQTAQLPLSENSAPGPQHGPPPGLR
                     PDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQ
                     APKVPPTPEPLPLNTPSAGTPQSQPPPLPPPPPAPGSAPPALPQEGPPEDTSQDLAPN
                     SVGAASTGGGTGGTHPNTPTAATANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVG
                     SEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAVEGGPPAQAPSAAQQ
                     PPSAPPPGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGQQMNMMMQRLGQD
                     SLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGNQMQRVPGFGGMQSI
                     PMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREEL
                     LRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQTHRQMDPTMFPGQMTGGDGLAGT
                     PMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQM
                     LMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMAGPQKMLMPSQFPNQGQQGFSGG
                     QGPYQAMPQDMGNTPDMFSPDQSSVPMGAVGTARLSHMPLPPASNPPGSVHSAPNRGL
                     GRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSAN
                     PPGPLKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQP
                     PLNINSSSTLGNLEQGALPPAGPRNSSSAPPANPPSSLMNPSLPFTSSPDPTPSQNPL
                     SLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQP
                     NQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGPSQN
                     SMMMAPGGPDSLNTPCGPVPSSSQMMSFPPRLQQPHGAMAATGGGGPGLQQHYPSGMA
                     LPPEDLPNQPPGPIPSQQHLMGKGMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTP
                     TGIPEFDLSRIIPSEKPSSTLQYFPKNENQPPKAQPPNLHLMNLQNMMAEQAPSRPPN
                     LPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFM
                     LMKQRGVGGEVYTQPPHMLSPQGSLMAPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPG
                     GMANLPF"
     exon            822..1207
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1327
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1538
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1623
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..2446
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            2447..3757
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            3758..4039
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
     exon            4040..5711
                     /gene="Bcl9l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgagtgga ggggcgagcg tggctccggc agcgcagggg atcccgggga ggcggcggcg
       61 cgcggcggag ccagtggccg gacatgcccc ggatccgggg ccgctgcagc accgccgccg
      121 cccggagcca gccggccgga cgcccgcacg cctgggtccc ctggcgccgc gccgcccggg
      181 ggctgcgatc tggaccctcg gcatccgacc aacaataagc gcctagacag ccccctcccc
      241 gccccgtgcc cgccgtcccc gcgggcctcg gggaaagtga aaggaggagg cgaaggaagg
      301 aaggaaggaa ggaagggagg aggaggagca ggagcggcag cagccggagc tgggaggttt
      361 gggccgagac cccagcccgg agcccgggca cggcggtgcg gtagctctcc cgctgctgcc
      421 ggcgcccagg accatgctcc gcggttggga ggcaggaacc caggcaacca gcgcctccgg
      481 gatacctgct cgcgggccgg gctggtatta agatcaaggc gtccaggatc aaaaagacca
      541 ccgcctgccc gccttctcca cgactccacc gtcctgctgg aggatcccag tccacccaac
      601 gaccctgatc tggttatggc gtccagctcc ggcctggcgt gaggaccccc gaccggtgcg
      661 agggagcccc catcccagac cacacccctg agcctgaacc tgacacacat tcctcagagt
      721 ccctgctcca gtaccgagta cctggctggg ccctgggcac gcacaggggt cgtagcccca
      781 ctgtgtgtgg gagccatgag gatcctggct aacaagacaa ggttacccca ccccaggagg
      841 agagaggctc cagggagtcc accgctgtcc cctcgaggcc actgcccccc tgccccagcc
      901 aagccaatgc acccagaaaa taaattgacc aatcatggca agacagggaa tggaggggcc
      961 caatcccagc accagaatgt gaaccaagga cccacctgca acctgggctc caagggcgtg
     1021 ggggcgggga gccatggggc caaggccaac cagatctcac ccagcaactc aagtctgaag
     1081 aacccccagg caggagtgtc tcctttcagc tccctcaaag gcaaggtgaa gcgagagcgg
     1141 agtgtgtccg tggactctgg agagcagcga gaagccggaa ctccatccct ggattcagag
     1201 gccaaagagg tggcaccccg gagtaaacgg aggtgtgtgc tggagcggaa gcagccatac
     1261 agtggggatg aatggtgctc tggaccagac agcgaggagg acgacaagcc cattggggcc
     1321 acccacaatt gtaatgtagc agacccagcc atggtggccc cacagttggg tcctggccaa
     1381 actgcccaac tgcccctcag tgagaacagt gcaccaggcc cccaacatgg ccccccgcca
     1441 ggccttcggc cagacgtccc tgggggtggg ggtgggggcg tcccaggaaa gcctccgtct
     1501 cagttcgtgt acgtcttcac cacccatctg gccaacacgg cggcagaagc agtgctacag
     1561 ggccgggcag agtccatcct cgcctaccac cagcagaacg tgccccgggc caagctggat
     1621 caggccccta aagtgccacc caccccagaa ccactacccc tgaacacgcc atcagcaggt
     1681 acaccacagt cccagccacc tccgttgcca ccgccaccac cagcccctgg cagtgcccct
     1741 cctgctctgc cccaggaggg gcctcctgaa gacaccagtc aggacctggc ccccaactca
     1801 gtgggagctg ccagcacagg tggtgggact gggggcaccc accccaacac cccaacggct
     1861 gccactgcta acaaccctct gcctcctgga ggagaccctg gcagtgctcc tggctctgcc
     1921 ctattgggcg aggccacgcc cacaggaaat gggcagagga acctggtggg ctctgagggc
     1981 ctgtccaaag agcagctgga gcaccgtgag cgctccctcc agacacttcg agacatagag
     2041 aggctgctgc tccgcagcgg ggagactgag cccttcctca aggggccccc tggaggagct
     2101 gttgagggag gcccgcccgc acaagcgccc tctgccgctc agcagcctcc ctccgcccct
     2161 cctccggggc tgaagaagta cgaggaacct ctgcagtcaa tgatttcaca gacacagagc
     2221 cttggaggcc ccccattgga gcacgaggtg ccggggcacc ctcagggcgg agacatggga
     2281 cagcaaatga acatgatgat gcagaggctg ggccaggaca gtctgacacc tgagcaggtg
     2341 gcctggcgca aactgcagga agagtactac gaggagaagc ggcggaaaga ggagcagatt
     2401 ggattgcatg ggggccgccc tctgcaggac atggtgggaa tggggggcaa ccagatgcaa
     2461 agggtgcctg gctttggagg tatgcagagt atacccatgg aagtacccat gaatgccatg
     2521 cagagacctg taaggccggg catggcctgg aatgaagact tgccccctat tgggggaccc
     2581 agcaactttg cccagaatgc tgtgccctat ccaggtgggc agggtgaggc agagcggttc
     2641 atgacccctc gtgtccggga ggagctgctg aggcaccagt tgctggagaa gcggtcaatg
     2701 ggcatgcagc ggcccctggg catggcgggt agtggcatgg gacagagcat ggaaatggaa
     2761 cggatgatac agacacatcg acagatggac cctaccatgt tcccagggca gatgactgga
     2821 ggagatggtc tggctggcac tcccatgggc atagagttcg gtggaggccg gggcctcctg
     2881 agccctccaa tgggacagtc tgggctgagg gaggtagacc cacccatggg accgggcaac
     2941 ctcaacatga acatgaatgt caacatgaac atgaacatga acctgaatgt gcagatgacg
     3001 ccacagcagc agatgctgat gtcacagaag atgcgaggcc ctggagacat gatgggtcct
     3061 cagggcctca gtcctgagga gatggctcga gttcgggccc agaacagtag tggcatgatg
     3121 gcgggtccac agaagatgct catgccttct cagtttccca accagggcca gcagggattc
     3181 tctgggggcc agggacccta ccaagccatg ccccaggaca tgggcaacac tccagacatg
     3241 tttagccctg atcagagttc agtgcccatg ggcgctgtgg gcaccgcccg gctcagccat
     3301 atgcctctgc cccctgcatc caatccccct gggtctgtgc actcagcccc caataggggg
     3361 cttggcaggc ggccttcaga tctcaccatc agtattaatc agatgggctc accaggcatg
     3421 gggcatctga agtcacccac ccttagccag gtgcactccc cgctggtcac ctcaccctct
     3481 gccaacctta agtcacccca gactccctca cagatggtac ccttgccttc tgccaaccca
     3541 ccaggacctc tcaagtcacc ccaggtcctc agctcttccc tcagtgtgcg ttcacccact
     3601 ggctcaccca gcaggctcaa gtctccctcc atggcggtgc cttctccggg ctgggtcgcc
     3661 tctcccaaga cagccatgcc tagtcctggg gtctcccaga ataaacagcc acctctcaac
     3721 ataaactctt cctctaccct gggcaacctg gaacagggtg ctctcccacc tgctggcccc
     3781 cggaacagct cctcagctcc tcccgccaac cctcccagca gcctcatgaa tcccagccta
     3841 ccgttcacat cctccccaga ccccacgcct tcccagaacc ctctgtcact gatgatgtct
     3901 cagatgtcca agtatgccat gcccagctct accccgctgt accacaatgc catcaagacc
     3961 atcgccacct cagatgacga gttgctgcct gaccggcccc tgctaccccc acccccacca
     4021 ccgcagggct ctgggccagg tatcagcaac aaccagccca accagatgca tatgaaccct
     4081 gctgctgccc agagccccat gggcatgaac ttgccaggcc agcagcccct gtcccatgag
     4141 cctccaccta ctatgttgcc ctcccccacc cctctggggt ccaacattcc actgcacccc
     4201 aatgcacagg ggactggggg cccttctcaa aactcaatga tgatggcccc aggaggccca
     4261 gactccctaa ataccccttg tggccctgtg cccagctctt cccagatgat gtcctttcct
     4321 cctcggctgc agcaacccca tggtgccatg gccgccactg ggggtggggg gcctggcctg
     4381 cagcagcact acccttcagg catggccctg ccccctgagg acctgcccaa ccagccacct
     4441 ggtcccatac cctcccagca gcacctgatg ggcaaaggca tggctggccg catgggcgat
     4501 gcgtacccac cgggggtact ccctggggtg gcatcggtac tgaatgaccc agagctgagt
     4561 gaggtgatcc ggcccacccc taccggcatt cctgagttcg acttatccag aatcatcccc
     4621 tctgagaaac cgagcagcac cctccaatac ttccccaaga acgagaacca gccccccaag
     4681 gcccagcccc ccaatctgca cctcatgaac ctgcagaaca tgatggcgga gcaggccccg
     4741 tctcggcccc ccaacctccc aggccaacag ggggtccagc ggggtctcag catgtccatg
     4801 tgccaccctg gacagatgtc cttgctgggc aggacaggtg tgcccccaca gcagggcatg
     4861 gtgccccacg gcctgcacca gggggtcatg tcccctccac agggcctcat gacccagcag
     4921 aattttatgc tgatgaaaca gaggggcgtg gggggtgagg tctacaccca gcctccccac
     4981 atgctctccc cacagggctc cctcatggcc cccccacccc agcagaacct catggtgtcc
     5041 caccctctgc ggcagcgcag tgtgtctctg gacagccaga tgggctacct cccaacgccg
     5101 ggcggcatgg ccaatctacc cttctagcag gcccctcggt ttggagctgg ggatactgaa
     5161 aatacgttaa ctttaaaaag ttttgctttt cctccagtgt tgggatggat ggcctgggtc
     5221 caggggtagg gtggagggga gggatagggc ttgtgtgggg agtggcgttt gtggaaacct
     5281 gatgtgctgg cagcttaggg ggggagcggc aagtgtcggt gaggagttgg aattggggtt
     5341 tgctccattt ctgacaccag gaccgctcct ccccggcccc cctagtccca cggagcttct
     5401 gttccccgtc gtctttgccc ctccccgctt tcagctgtgt ttcgggggtc cttggggaga
     5461 gaggagggtc ttccatcctc tgacctgttg tggacaggtc ggtttctctc cgccgggtct
     5521 ctctgctttg accccgtttt ccttctgcct catttcctct ccctactgac gtggctgacc
     5581 tcctctccca cgccccctgc aggcagctgg ccaggtgggc aggtgtcagc ggagctgtaa
     5641 atagagctgc gcttttgtgc cggtttgtgc gtgtgccgta tttctgtgtt ttgatagaag
     5701 tcacacacaa g
//
