LOCUS       NM_001173430            3610 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus BCAS3, microtubule associated cell migration
            factor (Bcas3), mRNA.
ACCESSION   NM_001173430 XM_001081081 XM_343952
VERSION     NM_001173430.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3610)
  AUTHORS   Jain,M., Bhat,G.P., Vijayraghavan,K. and Inamdar,M.S.
  TITLE     Rudhira/BCAS3 is a cytoskeletal protein that controls Cdc42
            activation and directional cell migration during angiogenesis
  JOURNAL   Exp Cell Res 318 (6), 753-767 (2012)
   PUBMED   22300583
REFERENCE   2  (bases 1 to 3610)
  AUTHORS   Siva,K., Venu,P., Mahadevan,A., S,K. S and Inamdar,M.S.
  TITLE     Human BCAS3 expression in embryonic stem cells and vascular
            precursors suggests a role in human embryogenesis and tumor
            angiogenesis
  JOURNAL   PLoS One 2 (11), e1202 (2007)
   PUBMED   18030336
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3610)
  AUTHORS   Gururaj,A.E., Peng,S., Vadlamudi,R.K. and Kumar,R.
  TITLE     Estrogen induces expression of BCAS3, a novel estrogen
            receptor-alpha coactivator, through proline-, glutamic acid-, and
            leucine-rich protein-1 (PELP1)
  JOURNAL   Mol Endocrinol 21 (8), 1847-1860 (2007)
   PUBMED   17505058
  REMARK    Erratum:[Mol Endocrinol. 2013 May;27(5):862]
REFERENCE   4  (bases 1 to 3610)
  AUTHORS   Gururaj,A.E., Holm,C., Landberg,G. and Kumar,R.
  TITLE     Breast cancer-amplified sequence 3, a target of
            metastasis-associated protein 1, contributes to tamoxifen
            resistance in premenopausal patients with breast cancer
  JOURNAL   Cell Cycle 5 (13), 1407-1410 (2006)
   PUBMED   16855396
REFERENCE   5  (bases 1 to 3610)
  AUTHORS   Siva,K. and Inamdar,M.S.
  TITLE     Rudhira is a cytoplasmic WD40 protein expressed in mouse embryonic
            stem cells and during embryonic erythropoiesis
  JOURNAL   Gene Expr Patterns 6 (2), 225-234 (2006)
   PUBMED   16099728
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before May 13, 2010 this sequence version replaced
            XM_343952.4, XM_001081081.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                JAXUCZ010000010.1  70711525-70711562
            39-128              JAXUCZ010000010.1  70712968-70713057
            129-216             JAXUCZ010000010.1  70713283-70713370
            217-271             JAXUCZ010000010.1  70718576-70718630
            272-347             JAXUCZ010000010.1  70721749-70721824
            348-454             JAXUCZ010000010.1  70731232-70731338
            455-536             JAXUCZ010000010.1  70756421-70756502
            537-609             JAXUCZ010000010.1  70775569-70775641
            610-717             JAXUCZ010000010.1  70813116-70813223
            718-794             JAXUCZ010000010.1  70818798-70818874
            795-871             JAXUCZ010000010.1  70826749-70826825
            872-955             JAXUCZ010000010.1  70831417-70831500
            956-1126            JAXUCZ010000010.1  70836800-70836970
            1127-1220           JAXUCZ010000010.1  70842668-70842761
            1221-1354           JAXUCZ010000010.1  70858321-70858454
            1355-1619           JAXUCZ010000010.1  70870195-70870459
            1620-1770           JAXUCZ010000010.1  70888631-70888781
            1771-1815           JAXUCZ010000010.1  70900753-70900797
            1816-1940           JAXUCZ010000010.1  70908766-70908890
            1941-2106           JAXUCZ010000010.1  70911842-70912007
            2107-2207           JAXUCZ010000010.1  70913674-70913774
            2208-2308           JAXUCZ010000010.1  70930304-70930404
            2309-2505           JAXUCZ010000010.1  70935526-70935722
            2506-2603           JAXUCZ010000010.1  70936885-70936982
            2604-2771           JAXUCZ010000010.1  71147150-71147317
            2772-3610           JAXUCZ010000010.1  71169654-71170492
FEATURES             Location/Qualifiers
     source          1..3610
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..3610
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /note="BCAS3, microtubule associated cell migration
                     factor"
                     /db_xref="GeneID:363662"
                     /db_xref="RGD:1560788"
     exon            1..38
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            39..128
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            129..216
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..2920
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /note="breast carcinoma amplified sequence 3"
                     /codon_start=1
                     /product="BCAS3 microtubule associated cell migration
                     factor"
                     /protein_id="NP_001166901.1"
                     /db_xref="GeneID:363662"
                     /db_xref="RGD:1560788"
                     /translation="MNETMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVV
                     PQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHELHSTGNEPPLLVMIGYSDGMQ
                     VWGIPISGEAQELFSVRHGPVRAARILPAPQLGAQKCDNFAEKRPLLGVCKSIGSSGT
                     TPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFF
                     VTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTL
                     KSGLTMVGKVVTQLTGTLPSGVTDDDIAIHCNSRRSPLVPGIITVIDTETVGEGQVLV
                     SEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQCA
                     VHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPR
                     VVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLSSQDSYNNFT
                     NNNPGNPRLSPLPSLMVVTPLAQIKQPMTLGTITKRTGPYLFGAGCFSIKAPCKVKPP
                     PQISPSKSMGGEFCVAAVFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVE
                     HMIEPRPISTAPKISDDTPLEIMTSPRASWTLVRTPQWNELQPPFNANHPLLLAAEAV
                     QYYQLLLAGSLPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWM
                     GPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSD
                     PVSMPGSSRPVSDRRGVSTVIDAASGTFDRSVTLLEVCGSWPEGFGLRHMSSMEHTEE
                     GLRERLADAMAESPSRDVVGSGTELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPT
                     NESQPLSLFPTGFP"
     exon            217..271
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            272..347
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            348..454
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            455..536
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            537..609
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            610..717
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            718..794
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            795..871
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            872..955
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1126
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1220
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1354
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1619
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            1620..1770
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1815
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1940
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            1941..2106
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..2207
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            2208..2308
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2505
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            2506..2603
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            2604..2771
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..3610
                     /gene="Bcas3"
                     /gene_synonym="RGD1560788"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctggagctgg agaacagcgt ttaccggcgg agcggccgtt ttaaattata ggaagaaaga
       61 ttcagcaaaa gagtgaactg ttctcacttt cagatgttag gcagttcaag gccagcctca
      121 attacagggt cttatgaatg aaaccatggc tacagattct cctagaagac ccagtcgctg
      181 cactggtgga gttgtggtcc gccctcaggc cgtcacggag cagtcctaca tggaaagcgt
      241 tgtgactttt ctgcaggatg tcgtgccaca ggcttacagt gggacacccc taacggaaga
      301 aaaggagaag atagtttggg tccggtttga gaatgcagat ctgaatgata catcacggaa
      361 tctagaattt catgaactgc atagcacggg aaatgagcct cctctgctgg ttatgatcgg
      421 ctacagtgac ggaatgcagg tgtggggcat ccctatcagc ggggaagccc aggagctctt
      481 ctctgttcga catggtccag tccgagcagc tagaatcttg cctgctccac agttgggtgc
      541 tcaaaagtgt gataactttg ctgagaaaag acctcttctt ggtgtttgta agagcattgg
      601 atcttcaggc acgacgccac catactgctg tgtggatctg tactcacttc gtacggggga
      661 gatggtcaag tccattcagt ttaaaacgcc catttatgat cttcattgta ataagcggat
      721 cctcgtcgta gtcctgcagg agaaaatcgc tgccttcgac agctgtactt tcacaaaaaa
      781 attttttgtc acaagttgtt atccttgtcc tgggccaaac atgaatccta ttgctcttgg
      841 gagccgttgg cttgcttatg cagaaaataa gctgattcgc tgtcaccagt cccgtggcgg
      901 agcctgtgga gacaacattc agtcttacac tgccactgtc attagtgctg ctaaaacact
      961 gaaaagtggc ctgacgatgg ttgggaaagt ggtgactcaa ctgacaggca cactgccctc
     1021 aggagtgaca gatgatgaca tagccataca ctgcaactca agacggagcc ccttggtgcc
     1081 gggcatcatc acagtcatag acactgagac agttggagag ggccaggtgc ttgtgagtga
     1141 ggattcagac agtgatggca ttgtggccca cttccctgcc cacgagaagc cagtgtgctg
     1201 tatggctttt aatacaagtg gaatgctttt agtcacaaca gatactcttg gccatgactt
     1261 tcatgtcttc caaatcctga ctcatccttg gtcatcctca cagtgtgctg tccatcacct
     1321 gtatacactt cacaggggag agaccgaggc caaagttcag gacatctgtt tcagccatga
     1381 ttgtcgttgg gtggtggtca gtaccctccg gggtacttcc cacgttttcc ccatcaaccc
     1441 ttatggtggc cagccttgtg tccgcacaca catgtcaccg cgagtagtga atcgcatgag
     1501 ccgtttccag aaaagtgctg ggctggaaga gattgaacaa gagctgacat ctaagcaagg
     1561 cggccgctgt agtcctgtcc caggcctgtc cagcagccct tccggctccc cgctgcatgg
     1621 gaagctgagt agccaagact cttacaataa ctttaccaac aacaaccctg gcaacccccg
     1681 gctttctccc ctccccagct tgatggtagt gacacctctt gcacaaatca agcagccaat
     1741 gacattgggg accatcacga aacgaacagg gccttatctc tttggagcgg ggtgtttttc
     1801 cataaaagct ccatgcaaag ttaaaccgcc tccacaaatt tctccaagca aatcgatggg
     1861 cggggagttt tgcgtggccg cagtgtttgg gacctccagg tcgtggtttg caaacaatgc
     1921 tggtctgaaa cgggaaaaag atcagtccaa acaagttgtg gttgaatctc tttatatcat
     1981 cagttgctac gggaccttag tggagcacat gattgagcct cggcctatca gtactgctcc
     2041 caagataagt gacgacacac cactggagat aatgacctca cctcgtgcca gctggacact
     2101 tgtcagaacg cctcagtgga acgaactgca gccaccattc aatgcgaatc accccctgct
     2161 ccttgcggca gaagcagtgc agtattacca gctcctgctg gccggctcac ttccccctgg
     2221 aagtcctggc cccattactc gacatgggtc ctatgacagt ttagcatctg accacagcgg
     2281 acaggaagat gaagaatggc tatcccaggt tgaaattgtg acacacactg gaccccacag
     2341 gcgcctatgg atgggtccac agttccagtt caaaaccatc cacccctcag gccagaccac
     2401 ggtcatatca tctagttctt ctgtgttaca gtctcatgga cctagtgaca caccacagcc
     2461 gctcttggac tttgatacag atgatctaga tcttaacagc ctcaggatcc agccggtccg
     2521 ctctgaccca gtcagcatgc cagggtcatc ccgtccagtc tctgatcgaa ggggagtttc
     2581 caccgtgatc gatgctgcct caggtacctt cgaccggagc gtgaccctgt tggaggtgtg
     2641 tgggagctgg cctgagggct tcgggctgcg acatatgtcc tccatggagc acacagaaga
     2701 gggcctccgg gaacggcttg cagatgccat ggccgagtca ccgagccgag acgttgtggg
     2761 atctggaaca gaacttcagc gagagggaag catcgagact ctgagtaaca gctcaggctc
     2821 caccagtggc agcatcccaa gaaactttga tggctaccga tctccgctcc cgaccaacga
     2881 gagccagccg ctcagcctct tccccactgg cttcccatag acaccagcca cctgcttctg
     2941 actggctggc ctgctcaccc cctagaggga ctgacagggg tggagagaaa tgcccctatc
     3001 tccctacacc cccaccccca taaacctctg gtcccaccct tttcagtctc ctcaacccca
     3061 ccttcccgga gcttagtgac agcagccgct catccctaac tggactgaag acaccttcgg
     3121 aacacctcag tacaccctga cttctcccac tcctgtcagt gggggctgtg gcctgaagag
     3181 actgcagaac tcagtccctt ctctctttgc acataatgtc ctgcattgga tccgcttttg
     3241 tattttctaa ctacccacag gggactggaa cagtggccag atcttagggc cttgggtagg
     3301 gaagagttga aaggtccagc caggcatttt ggtggacatc agccctagcc cagttgaggc
     3361 tgtgatgcac actgccccca ggtatcagtt ctttctaaaa aaggggttaa ctgaggccta
     3421 gagtgatagg gaaaaaggaa agacctcccc ttgcccctgc ttccctgttg gctcatgggg
     3481 agatttgtct gtcttatctt taaacccttg taccctggtc ctgtgctgtt cagtgaagga
     3541 aactgaagtt actgaggccg tgtcagaagt gcacgtcttg tccaataaat cttgctgcaa
     3601 ttggtgttca
//
