LOCUS       NM_001106458            1083 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus BCAS2, pre-mRNA processing factor (Bcas2), mRNA.
ACCESSION   NM_001106458 XM_001064236 XM_215664
VERSION     NM_001106458.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1083)
  AUTHORS   Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K,
            Urlaub H, Kastner B, Stark H and Luhrmann R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   2  (bases 1 to 1083)
  AUTHORS   Marechal A, Li JM, Ji XY, Wu CS, Yazinski SA, Nguyen HD, Liu S,
            Jimenez AE, Jin J and Zou L.
  TITLE     PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and
            drives ATR activation via a ubiquitin-mediated circuitry
  JOURNAL   Mol Cell 53 (2), 235-246 (2014)
   PUBMED   24332808
REFERENCE   3  (bases 1 to 1083)
  AUTHORS   Chanarat S and Strasser K.
  TITLE     Splicing and beyond: the many faces of the Prp19 complex
  JOURNAL   Biochim Biophys Acta 1833 (10), 2126-2134 (2013)
   PUBMED   23742842
  REMARK    Review article
REFERENCE   4  (bases 1 to 1083)
  AUTHORS   Maass N, Rosel F, Schem C, Hitomi J, Jonat W and Nagasaki K.
  TITLE     Amplification of the BCAS2 gene at chromosome 1p13.3-21 in human
            primary breast cancer
  JOURNAL   Cancer Lett 185 (2), 219-223 (2002)
   PUBMED   12169396
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC169122.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001106458.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169122.1, FQ226799.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1083
                     /gene="Bcas2"
                     /note="BCAS2, pre-mRNA processing factor"
                     /db_xref="GeneID:295334"
                     /db_xref="RGD:1306485"
     exon            1..110
                     /gene="Bcas2"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..695
                     /gene="Bcas2"
                     /note="breast carcinoma amplified sequence 2"
                     /codon_start=1
                     /product="pre-mRNA-splicing factor SPF27"
                     /protein_id="NP_001099928.1"
                     /db_xref="GeneID:295334"
                     /db_xref="RGD:1306485"
                     /translation="MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYR
                     PTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITA
                     WQDCVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHI
                     QDLNWQRKNMQLTAGAKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANK
                     ENIRQDF"
     exon            111..203
                     /gene="Bcas2"
                     /inference="alignment:Splign:2.1.0"
     exon            204..274
                     /gene="Bcas2"
                     /inference="alignment:Splign:2.1.0"
     exon            275..436
                     /gene="Bcas2"
                     /inference="alignment:Splign:2.1.0"
     exon            437..487
                     /gene="Bcas2"
                     /inference="alignment:Splign:2.1.0"
     exon            488..568
                     /gene="Bcas2"
                     /inference="alignment:Splign:2.1.0"
     exon            569..1054
                     /gene="Bcas2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtacagtg ccgcgcgatg gcgggcacgg gcttggtagc gggggaggtg gtagtggatg
       61 cgctacccta ctttgaccaa ggctatgaag cgcctggcgt gcgggaagcg gctgcggccc
      121 tggtggagga ggaaacgcgc agataccgac ctaccaagaa ctacctgagc tacctgacag
      181 ccccagatta ttctgccttt gaaacagaca taatgagaaa tgagtttgaa agactggctg
      241 ctcgacaacc aattgaatta ctcagcatga agcgatatga actgccagcc ccttcctcgg
      301 gtcaaaaaaa tgacatcact gcgtggcaag actgtgtaaa caattctatg gcccagctgg
      361 agcatcaggc agtgcggatt gagaatctgg aactgatgtc acagcatggg tgtaacgcct
      421 ggaaagtgta caacgaaaac cttgttcaca tgattgaaca tgcacagaaa gagcttcaga
      481 agttaaggaa gcatattcag gatttaaact ggcagcgcaa gaacatgcag cttacagctg
      541 gggctaagct gagagaaatg gagtcaaatt gggtgtcgct ggtgagtaag aactatgaga
      601 ttgagcggac tattgtacag ttggagaacg agatctatca aatcaagcag cagcacggtg
      661 aggcaaacaa ggaaaacatc cgccaagact tctgaggacg tgggcagcaa ggaatcgaag
      721 tgagctccac gagactcggc acggactttc tcaaagcgac tgttggtgac tcagtgttta
      781 gagactgtgg gctatgtaaa ctgttgtatt gcttttgtgt gtgtcttagc aaaataaaga
      841 ttgtcaacat gttgctattt ttatagctat aaaaacccga gttttcaaag tgagtatgac
      901 tttacaataa tcttgtcata ttttgtagaa gtcttttttt ttttaaggct tcaatttttg
      961 taatgaagct tctttatttt taaggtttcc aatgtgttca ggaagctgag aaccttgaat
     1021 ttgtgttttg ttgaataaag gtctaagcat ttgtaaaaaa aaaaaaaaaa aaaaaaaaaa
     1081 aaa
//
