LOCUS       NM_001415675            3072 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus brain enriched myelin associated protein 1
            (Bcas1), transcript variant 1, mRNA.
ACCESSION   NM_001415675 XM_008762466
VERSION     NM_001415675.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3072)
  AUTHORS   Ishimoto,T., Ninomiya,K., Inoue,R., Koike,M., Uchiyama,Y. and
            Mori,H.
  TITLE     Mice lacking BCAS1, a novel myelin-associated protein, display
            hypomyelination, schizophrenia-like abnormal behaviors, and
            upregulation of inflammatory genes in the brain
  JOURNAL   Glia 65 (5), 727-739 (2017)
   PUBMED   28230289
REFERENCE   2  (bases 1 to 3072)
  AUTHORS   Ninomiya,K., Ishimoto,T. and Taguchi,T.
  TITLE     Subcellular localization of PMES-2 proteins regulated by their two
            cytoskeleton-associated domains
  JOURNAL   Cell Mol Neurobiol 25 (5), 899-911 (2005)
   PUBMED   16133941
  REMARK    GeneRIF: PMES-2 possibly modifies the cytoskeletal architecture and
            protein transport at the synapse and/or regulates signal
            transduction from the synapse to the nucleus.
REFERENCE   3  (bases 1 to 3072)
  AUTHORS   Ishimoto,T., Ninomiya,K., Miyaji,K., Uyeda,A., Kasai,M. and
            Taguchi,T.
  TITLE     Cloning and characterization of a novel synaptosome-enriched mRNA
            that encodes 31 kDa protein
  JOURNAL   Biochim Biophys Acta 1579 (2-3), 189-195 (2002)
   PUBMED   12427555
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Dec 22, 2022 this sequence version replaced XM_008762466.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760393
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               JAXUCZ010000003.1  179637644-179637743 c
            101-177             JAXUCZ010000003.1  179630520-179630596 c
            178-256             JAXUCZ010000003.1  179628794-179628872 c
            257-831             JAXUCZ010000003.1  179615311-179615885 c
            832-987             JAXUCZ010000003.1  179596742-179596897 c
            988-1032            JAXUCZ010000003.1  179596114-179596158 c
            1033-1167           JAXUCZ010000003.1  179592759-179592893 c
            1168-1380           JAXUCZ010000003.1  179586472-179586684 c
            1381-1422           JAXUCZ010000003.1  179578568-179578609 c
            1423-1590           JAXUCZ010000003.1  179573410-179573577 c
            1591-1656           JAXUCZ010000003.1  179565873-179565938 c
            1657-1935           JAXUCZ010000003.1  179559351-179559629 c
            1936-3072           JAXUCZ010000003.1  179554754-179555890 c
FEATURES             Location/Qualifiers
     source          1..3072
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..3072
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /note="brain enriched myelin associated protein 1"
                     /db_xref="GeneID:246755"
                     /db_xref="RGD:628644"
     exon            1..100
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            101..177
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..2010
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     breast carcinoma-amplified sequence 1 homolog; band 83;
                     breast carcinoma amplified sequence 1"
                     /codon_start=1
                     /product="breast carcinoma-amplified sequence 1 homolog
                     isoform 1"
                     /protein_id="NP_001402604.1"
                     /db_xref="GeneID:246755"
                     /db_xref="RGD:628644"
                     /translation="MGNQMSVPLRPGDQEHDPEADTYKVTSDNECVQNGIPVVVSTRV
                     IQHYEEVDLGINSLKDNVPASSPETMEAHAVADASGKNLGKGSKPKAPAARSHFFLTL
                     SRPVPGRPGDQGTDSSAASGRLDVSPGTAPENKDPSEHGALPVAAAPGPAPDKTPGCT
                     EAKQQTLPATSPLAPSPPESQAEAPSRPKDFSFLNRLFKLDKGRESAPADSPPEEGKG
                     SKSQERAIEAPAVPGNPHGVSAGKDIVDSEERKQEVDTLSYSVPADPEVLGTTKEDPQ
                     VVDATENSNSIMSFFKTLVSPNKTETKKDPEDTKATKADSVCDGHAGQKMSETQAKSK
                     KKRLDSPRLGLSFRKFFRHKDAENSPTTPANLKSDKADLTPQETQGTAKSSKGSSQPG
                     QAPSAGTSDTAREGGKEKAGPTSLPLGKLFWKKSVKEDSLSTGAEENAVCEPPVETVR
                     LEEVESTLQTVDLTEKETQTEPTDVKVKEESKPRRTPLMAFLRQMSVRGSEGITRSEE
                     SNGKDSSCQTSNSTEKTPSPPEPEPAGTAQKNKETSSKDKKSVDKKSAAESNKQKNGK
                     PEAREPAPCVQQPTVEVNALQTGDKTPKRSEKRRQSLGGFLKGLGPKRMLDAQVQTDP
                     VSIGPVGKSK"
     exon            178..256
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            257..831
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            832..987
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1032
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1167
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1380
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1422
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..1590
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1656
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1935
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..3072
                     /gene="Bcas1"
                     /gene_synonym="Band83; Pmes-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtctagtac caggcagcaa cagctgaaga ctcaggaccc tgagcagaac cgactgctgg
       61 aaactgtggg ggacacaaga tactccaacc agctcaccag gaacaatggg aaaccagatg
      121 agcgtcccac taagacctgg agaccaggag catgacccgg aagcagacac ttacaaggtg
      181 acgtcggaca acgagtgtgt tcagaatggc atcccggtgg tggtgtccac tcgtgtgatt
      241 caacactatg aggaagtcga tttgggaatc aacagcttga aggataatgt gcccgcttct
      301 tcccccgaga caatggaggc tcacgctgtg gctgatgcca gcggaaagaa tcttgggaaa
      361 ggatccaagc ccaaagcacc agctgctagg tcccattttt tcttgacact ctctcggcct
      421 gtaccaggac gtcccgggga ccaaggcaca gattcatcgg ctgcatcggg gaggcttgat
      481 gtcagcccag gcacggcgcc tgagaacaaa gacccgagtg agcacggggc acttccggtg
      541 gcagctgcac cagggccggc tccagataaa accccagggt gcactgaggc caagcagcag
      601 accctccctg ccaccagccc actggcacct tcaccacctg agtcccaggc agaagccccg
      661 tccaggccca aggatttcag ctttttgaac agactcttta aactggacaa gggaagagaa
      721 agcgcgccgg ctgacagccc gcctgaagaa gggaaagggt ccaaaagcca agaacgggcc
      781 atagaggctc ctgctgtacc agggaatcct catggtgtct ctgcagggaa ggacatagtg
      841 gacagcgagg agagaaagca agaagttgac actctgagtt attctgtccc tgcggatcca
      901 gaggtgctgg ggaccacgaa ggaggacccc caggtggtag acgccacaga gaatagtaat
      961 tccatcatga gcttcttcaa gacactagtt tcgcctaaca aaactgaaac aaagaaggac
     1021 ccagaagaca cgaaggcaac caaggcagac agtgtctgcg atggacacgc tggccagaag
     1081 atgtcggaga cgcaggctaa aagcaagaag aaacgcctgg acagccccag gctaggactc
     1141 tcctttagaa aattctttag gcacaaggac gccgagaatt cacccactac tccagccaat
     1201 ctcaagtcgg acaaagccga cctcaccccc caggagaccc aagggacagc caagagttcc
     1261 aagggcagca gtcagccagg ccaggcgcca tctgcgggaa ccagcgacac agcaagagag
     1321 ggtggcaagg agaaggcggg gcccacctcc ttaccactgg gaaagctgtt ttggaagaag
     1381 tcagttaagg aggattcact ttccacaggc gcagaggaga acgcggtgtg tgagccacca
     1441 gtagagactg taaggcttga ggaagtagaa tccaccttac aaaccgtgga tctcactgag
     1501 aaagaaaccc agactgagcc cacagatgtg aaagtcaaag aagaaagcaa accccggagg
     1561 acccctctga tggcgtttct cagacaaatg tcagtgagag ggagcgaagg gatcacccgc
     1621 tcggaagaga gtaacgggaa agactccagc tgccaaacat caaactccac ggagaagacg
     1681 ccctcacccc cagagccgga gcccgcgggg acagcccaga aaaacaaaga gacctcctcg
     1741 aaggacaaga agtcggtgga caagaagtca gcggctgaga gcaacaagca gaagaatggc
     1801 aaaccggaag ccagagaacc agcgccgtgt gtgcagcagc ccacggtgga ggtgaacgcg
     1861 ctgcagactg gggacaagac cccaaagagg tctgagaagc ggcgacagtc cctcgggggc
     1921 tttctgaagg gcctgggacc aaagcggatg ttggatgctc aagtgcaaac ggaccccgta
     1981 tccatcggac cagttggaaa atccaagtaa acaaatcacc tagctcccac caggttctcc
     2041 tcccactcca tctcctgtct agacccacac cgtgtatata tatatatttt ttttttcttc
     2101 tggccagcca atgaaattct gcctgaattg ttgtagatca aggtgtatta tttatgactc
     2161 tggtccagtc tttcctggca tataagtgta taaatgggtt agcaggttaa ccagttgatc
     2221 taggggagca ggtgagtgcc agggtgggag gaagtaagta gataaaggca tttgtgttaa
     2281 gttatgaaaa aaaatggcag gtatccagta aggtgcagaa gaaaagtgct taggagaaaa
     2341 agaatatccg gctctgtagc cagtgttgct gtacgctctg aacctgaaga ggggaaggga
     2401 agactggctt agttcatttc acatttgggg gaaggaggac tcagggcagg ctctacgttg
     2461 ggcacctgcc aacttttgga atagaatgtg tgggctataa aagaattggt tttcaaatag
     2521 ggtccttgaa agttatcggt gatggggaag tgattcgctg aggagggctc acagtgattt
     2581 gggggaacaa ttacttctga ggcacaggga caagggcatg aattaccaac ttcaaaagaa
     2641 aaaaaaaacg gcaaaatgaa agttgcaggt tcgttttgcg acacaagggg gcgccaagac
     2701 ctccgctttc ccctttgcat ccggtacccc taacaaagat ttgtttctgt aatatttcgt
     2761 tattaatgtt tctcagatgg ctgagggact tgcttcatct gttccgtctg acgcttatct
     2821 cacgcctgtc tgtaatatcc taatgttttc ataatgtgct ctgataaaaa ccctccccta
     2881 acccagttaa taaaaattga cagattatgc aaatacttga ggtgtttttt ttttttaatt
     2941 cttgtacaga gaacagagtt ggaccgtgag tccattaaga cggaatcgca aagcagcgtt
     3001 tgattgactg ataatccttt gtatcgtacc tttctttttc caatttaata aaaaaaaatg
     3061 aattttagaa aa
//
