LOCUS       NM_001107158            8368 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus bromodomain adjacent to zinc finger domain, 2A
            (Baz2a), mRNA.
ACCESSION   NM_001107158 XM_001070233 XM_039078967 XM_222315
VERSION     NM_001107158.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8368)
  AUTHORS   Zhai,N., Zhao,Z.L., Cheng,M.B., Di,Y.W., Yan,H.X., Cao,C.Y.,
            Dai,H., Zhang,Y. and Shen,Y.F.
  TITLE     Human PIH1 associates with histone H4 to mediate the
            glucose-dependent enhancement of pre-rRNA synthesis
  JOURNAL   J Mol Cell Biol 4 (4), 231-241 (2012)
   PUBMED   22368283
REFERENCE   2  (bases 1 to 8368)
  AUTHORS   Guetg,C., Lienemann,P., Sirri,V., Grummt,I., Hernandez-Verdun,D.,
            Hottiger,M.O., Fussenegger,M. and Santoro,R.
  TITLE     The NoRC complex mediates the heterochromatin formation and
            stability of silent rRNA genes and centromeric repeats
  JOURNAL   EMBO J 29 (13), 2135-2146 (2010)
   PUBMED   20168299
  REMARK    Erratum:[EMBO J. 2010 Jul 7;29(13):2253]
REFERENCE   3  (bases 1 to 8368)
  AUTHORS   Zhou,Y., Schmitz,K.M., Mayer,C., Yuan,X., Akhtar,A. and Grummt,I.
  TITLE     Reversible acetylation of the chromatin remodelling complex NoRC is
            required for non-coding RNA-dependent silencing
  JOURNAL   Nat Cell Biol 11 (8), 1010-1016 (2009)
   PUBMED   19578370
REFERENCE   4  (bases 1 to 8368)
  AUTHORS   Mayer,C., Neubert,M. and Grummt,I.
  TITLE     The structure of NoRC-associated RNA is crucial for targeting the
            chromatin remodelling complex NoRC to the nucleolus
  JOURNAL   EMBO Rep 9 (8), 774-780 (2008)
   PUBMED   18600236
REFERENCE   5  (bases 1 to 8368)
  AUTHORS   Mayer,C., Schmitz,K.M., Li,J., Grummt,I. and Santoro,R.
  TITLE     Intergenic transcripts regulate the epigenetic state of rRNA genes
  JOURNAL   Mol Cell 22 (3), 351-361 (2006)
   PUBMED   16678107
REFERENCE   6  (bases 1 to 8368)
  AUTHORS   Zhou,Y. and Grummt,I.
  TITLE     The PHD finger/bromodomain of NoRC interacts with acetylated
            histone H4K16 and is sufficient for rDNA silencing
  JOURNAL   Curr Biol 15 (15), 1434-1438 (2005)
   PUBMED   16085498
REFERENCE   7  (bases 1 to 8368)
  AUTHORS   Santoro,R., Li,J. and Grummt,I.
  TITLE     The nucleolar remodeling complex NoRC mediates heterochromatin
            formation and silencing of ribosomal gene transcription
  JOURNAL   Nat Genet 32 (3), 393-396 (2002)
   PUBMED   12368916
REFERENCE   8  (bases 1 to 8368)
  AUTHORS   Zhou,Y., Santoro,R. and Grummt,I.
  TITLE     The chromatin remodeling complex NoRC targets HDAC1 to the
            ribosomal gene promoter and represses RNA polymerase I
            transcription
  JOURNAL   EMBO J 21 (17), 4632-4640 (2002)
   PUBMED   12198165
REFERENCE   9  (bases 1 to 8368)
  AUTHORS   Strohner,R., Nemeth,A., Jansa,P., Hofmann-Rohrer,U., Santoro,R.,
            Langst,G. and Grummt,I.
  TITLE     NoRC--a novel member of mammalian ISWI-containing chromatin
            remodeling machines
  JOURNAL   EMBO J 20 (17), 4892-4900 (2001)
   PUBMED   11532953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Mar 5, 2021 this sequence version replaced
            XM_039078967.1, NM_001107158.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-199               JAXUCZ010000007.1  1112823-1113021
            200-337             JAXUCZ010000007.1  1123788-1123925
            338-931             JAXUCZ010000007.1  1125815-1126408
            932-1117            JAXUCZ010000007.1  1127772-1127957
            1118-1336           JAXUCZ010000007.1  1128640-1128858
            1337-1786           JAXUCZ010000007.1  1129397-1129846
            1787-1847           JAXUCZ010000007.1  1130127-1130187
            1848-1956           JAXUCZ010000007.1  1131357-1131465
            1957-2058           JAXUCZ010000007.1  1131615-1131716
            2059-2275           JAXUCZ010000007.1  1131865-1132081
            2276-2376           JAXUCZ010000007.1  1133939-1134039
            2377-2442           JAXUCZ010000007.1  1134310-1134375
            2443-2658           JAXUCZ010000007.1  1134636-1134851
            2659-2913           JAXUCZ010000007.1  1134969-1135223
            2914-3128           JAXUCZ010000007.1  1136888-1137102
            3129-3203           JAXUCZ010000007.1  1137431-1137505
            3204-3384           JAXUCZ010000007.1  1137644-1137824
            3385-3444           JAXUCZ010000007.1  1137925-1137984
            3445-3589           JAXUCZ010000007.1  1138159-1138303
            3590-4251           JAXUCZ010000007.1  1139229-1139890
            4252-4474           JAXUCZ010000007.1  1140005-1140227
            4475-4630           JAXUCZ010000007.1  1140346-1140501
            4631-4782           JAXUCZ010000007.1  1140578-1140729
            4783-5072           JAXUCZ010000007.1  1141228-1141517
            5073-5352           JAXUCZ010000007.1  1141608-1141887
            5353-5591           JAXUCZ010000007.1  1142281-1142519
            5592-5735           JAXUCZ010000007.1  1142608-1142751
            5736-8368           JAXUCZ010000007.1  1142875-1145507
FEATURES             Location/Qualifiers
     source          1..8368
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..8368
                     /gene="Baz2a"
                     /note="bromodomain adjacent to zinc finger domain, 2A"
                     /db_xref="GeneID:304601"
                     /db_xref="RGD:1305037"
     exon            1..199
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            200..337
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..5901
                     /gene="Baz2a"
                     /codon_start=1
                     /product="bromodomain adjacent to zinc finger domain
                     protein 2A"
                     /protein_id="NP_001100628.2"
                     /db_xref="GeneID:304601"
                     /db_xref="RGD:1305037"
                     /translation="MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQG
                     KSLNGDVNVNGLSTVSHTTTSGILNSAPHSSSTSHLHHPNVAYDCLWNYSQYPSANPG
                     NNLKDPPLLSQYPGGQYPLNGILGGSQQPSSPSHNTNLRAGSQEFWANGTQSPVGLNF
                     DSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQGVSSDLHPDEAAE
                     KELTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVSSVESLHQEVSVLVPDPTVSCL
                     DDPSHLPEQLEDTPILSEDSLEPFDSLAAEPVSEGLYSIDDTELMGTEDKLPLEDNPV
                     ISALDCPALSNANAFSLLAEDSQTSASIFVSPTSPPVLGESVLQDNSFGLNSCSDSEQ
                     EEMETQSSNFQRSLTEPAPDQPPSIQLHPAASPTASPVASLAASAEISPAASPVASSP
                     IPPEVFPAVSPASSPALPAISLEASMAAPVTSPPGSPEPSAPAALQTVSTASKDGSSA
                     PGACAGQEEMAGEAVAGSGIGDVLKRHIATPEEVRLPLQHGWRREVRIKKGSHRWQGE
                     TWYYGPCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWV
                     QLSAEEIPSRIQAITGRRGRPRNSEKSKDKDKEVPRVRRGRGRPPKVQVPGLLTETDN
                     RLPKKLETQETLSEEDKAKMTKSKKKVRQKVQRGESQPPVQGQARNKRKQDTKNSKPK
                     DTKRKFKAEKEKMKTKQEKLKEKVKREKKEKVKVKGKEEPRARPSCRATQRRLEERQR
                     QQVILEEMKKPTEDMCLADHQPLPDFTRIPGLTLSSRAFSDCLTIVEFLHSFGKVLGF
                     DLTKDVPSLGVLQEGLLCQGDSLDKVQDLLVRLLKAALHDPGLPSYCQSLKILGEKVS
                     EIPLTRDNVSEVLRCFLMAYRVEPSFCDSLRTQPFQAQPPQQKASVLAFLVHELNGST
                     IVINEIDKTLENMSSYRKNKWIVEGRLRRLKTALAKRTGRPEVMMEGVDDSLGRRRSS
                     RIMEETSGIEEEEEEENTVAVHGRRGRRDGEVDVAASSIPELERQIEKLSKRQLFFRK
                     KLLHSSQMLRAVSLGQDRFRRHYWVLPCLAGIFVEGSEGSAVTEDGIKQETESLMEAV
                     TSTPSSAQVSVKREPTGSTTSTSPARSRGRPRKPKPGSLQPQHLKSTIREHDSEQAQS
                     QAHPRAQPQPQPQPQPQPQPQTPIQPHLQSSNGFLEPEGSPFSLGQSQHDLSQSAFLS
                     WLSQTQSHNSLLSSSVLTPDSSPGKLDSAPSQSLEEPEPDETQPCPGPQGPWFNFSAQ
                     IPCDAAPTPPPAVSEDQPTPSLQLPASSKPMNTPGAANPCSPVQLSFTHLPGGGPKRL
                     SGDSEEIPQSPTGLGQPKRRGRPPSKFFKQVEQHYLTQLTAQPIPPDMCSGWWWIRDP
                     ETLDVLLKALHPRGIREKALHKHLSKHKDFLQEVCLQPLTDPIFEPSQLPALEEGIMS
                     WSPKEKTFETDLAVLQWVEELERRVVLSDLQIRGWTCPSPDSTREDLTYCEHLPDSQE
                     DIPWRGRGREGAVPQRQNTNPLDLAVMRLAVLEQNVERRYLREPLWAAHEVVVEKALL
                     STPSGEPDSATTEISYEITPRVRVWRQTLERCRSAAQVCLCVGQLERSIAWEKSVNKV
                     TCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCAVCLAQQVEEEYTQR
                     PASLKRGQKRKSSFPLTFTEGDSRRRRRRRRMLSRNRESPAVSQYPEDRLSPSKRRRL
                     SMRSHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRVIKNPMDFSTMRERLL
                     RGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL"
     exon            338..931
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1117
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1336
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1786
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1847
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1848..1956
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..2058
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            2059..2275
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            2276..2376
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2442
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2658
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            2659..2913
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            2914..3128
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            3129..3203
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            3204..3384
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            3385..3444
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            3445..3589
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            3590..4251
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            4252..4474
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            4475..4630
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            4631..4782
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            4783..5072
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            5073..5352
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            5353..5591
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            5592..5735
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
     exon            5736..8368
                     /gene="Baz2a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcctcccc tgccggccat gttggctcgg ctctggcccc gcggttgagc cgcgaccccc
       61 tgccccctcc cacaccccgc accctgcacc cctctcccgc gggcgtctcc tccctcctgg
      121 cgcccagagc ctggccatgt gaaccgcccg tcccccgggg agaagcgagc cccgacccgg
      181 ccggacgcgg tcgcctcaga aatggaggca aacgaccatt ttaattttac tggccttcct
      241 cctgcaccag ctgcctcagg actgaaaccc tctccttcct caggggaggg cctctacact
      301 aacgggtctc ccatgaactt cccccagcaa gggaaaagtt tgaatgggga tgtgaatgtt
      361 aatggcttat ctactgtatc tcacactact acttcaggga ttttgaactc tgctccccac
      421 tcctctagca cctcacacct ccatcaccct aacgtggcct acgactgtct ttggaactac
      481 tcacagtacc catctgccaa tcctggcaac aacctcaagg acccacccct tctttctcaa
      541 taccctgggg ggcaataccc gctcaacggt atccttgggg gcagccaaca accttcatcc
      601 ccaagtcaca acactaatct tcgagctggg agccaagagt tctgggccaa tggtacccag
      661 agtcccgtgg ggcttaactt cgattcacag gaactgtatg attcttttcc tgaccagaat
      721 tttgaggtga tgcccaatgg acccccaagt tttttcacct ccccacagac ttctccaatg
      781 ctggggtcta gtatccagac ctttgcacct tcccagggtg taagcagtga cctccatcct
      841 gatgaggcag cggaaaagga gctgacctca gttgtggcag aaaatggcac tggcttggta
      901 ggcagcctgg aactggagga agagcagcca gaactaaaga tgtgtggcta caatggttct
      961 gtctcctctg tggagtcttt gcaccaagaa gtctcggtcc tggtccctga ccccacagtg
     1021 agctgtctgg atgatccttc acatcttcct gagcaactgg aagacactcc aatcctcagt
     1081 gaagactccc tcgagccctt tgactctctg gcagcagagc cagtgagtga aggactttat
     1141 agtatagatg acacagagct gatgggtaca gaagacaagc tccctctgga ggacaaccct
     1201 gtgatctctg ccctcgattg ccctgctctc agtaatgcta atgccttcag tctcctggca
     1261 gaggacagcc aaacatcagc ctccattttt gtcagtccta cctccccacc tgtcttaggg
     1321 gagtctgtct tgcaagataa tagctttgga ctgaacagtt gcagtgactc tgaacaggaa
     1381 gaaatggaga cccagtcttc aaacttccaa cgttccttga ctgagccagc ccccgaccag
     1441 ccacctagta ttcagctaca tccagcagcc tcaccaacag cctccccagt agcctccttg
     1501 gcagcatctg cagaaatctc tccagccgca tctccagtag catcctcgcc tatccctcct
     1561 gaagtcttcc cagcagtctc tccagcttcc tcacctgctc tcccagccat ctctttggaa
     1621 gcttctatgg cggctcccgt gacttctcct ccaggttccc ctgagccttc tgcacccgct
     1681 gccttgcaga cagtctccac agctagtaaa gatggtagca gtgcccctgg agcttgtgct
     1741 ggtcaggaag agatggctgg agaagcagtt gcaggatctg ggattggtga tgtactgaag
     1801 agacatattg ctaccccaga agaagttcgt cttcccctcc aacatgggtg gcgaagagaa
     1861 gtgcgcatta agaagggcag ccatcggtgg cagggggaga cttggtatta tggcccctgt
     1921 gggaagagaa tgaagcaatt tccagaagtt atcaagtacc tgagccgaaa tgtggtgcac
     1981 agtgtccgcc gagagcactt cagcttcagc ccccgaatgc ctgttggaga tttctttgaa
     2041 gaaagagata caccagaggg cttgcaatgg gtccagttgt cagcagagga gattccttcc
     2101 aggattcaag ccatcactgg cagacgaggc cgacctcgaa acagtgagaa gagcaaggac
     2161 aaggacaagg aggtccccag agtgaggcgg ggccggggcc ggcctcctaa ggtccaagtg
     2221 cctggactgc tgactgaaac ggacaaccga cttccaaaaa aactggaaac ccaagaaaca
     2281 ctgagtgagg aagataaagc aaagatgact aagagcaaaa agaaggtgag gcagaaggtt
     2341 cagcggggag agagtcagcc tcctgtccaa gggcaggcca gaaacaagag gaagcaagac
     2401 accaagaact caaagccgaa ggacactaag aggaagttca aggctgagaa agagaagatg
     2461 aagacaaagc aggagaagct gaaggaaaag gtgaagaggg aaaagaaaga aaaggtaaaa
     2521 gtgaagggaa aggaagagcc cagagccagg ccatcctgta gagctacaca gaggcgactg
     2581 gaggagcggc agaggcagca ggtcatcttg gaggagatga agaagcccac ggaggatatg
     2641 tgtctggctg accaccagcc cctgcctgac ttcacacgca tccctggttt gacactgtcc
     2701 agcagggctt tctcagattg cttgaccatc gtggagttcc tgcacagttt tggcaaagtg
     2761 ctaggctttg accttaccaa agatgttcct agtctcggag tcctgcagga ggggctctta
     2821 tgtcaaggtg acagcttgga caaagtgcag gacctgctgg tccggctcct gaaggctgca
     2881 cttcacgatc ctggtttgcc ctcctactgt cagtccctaa agatcctggg ggagaaggtg
     2941 tcagagatcc cattgaccag agacaatgtg tctgaggtac tgcgctgctt cctcatggca
     3001 tacagagtgg agccgtcctt ctgtgacagt ctgcgaactc agccttttca ggcccagccg
     3061 cctcagcaga aggcttctgt cctagccttc cttgtgcatg agctcaacgg ctccaccatt
     3121 gtcatcaatg agattgacaa gactctggag aacatgtcta gctacaggaa aaacaaatgg
     3181 attgttgaag gccgactccg gagactgaaa actgccctag ccaagcgaac tgggcggcct
     3241 gaagttatga tggaaggggt agatgacagc ctgggacgga ggcgcagctc tcggatcatg
     3301 gaggagacca gtggcataga agaggaggaa gaggaggaaa atacagtagc tgttcatggc
     3361 cgcaggggtc gaagagatgg ggaggttgat gttgcagcat ctagcatccc agagctagag
     3421 cgccagatag agaaactcag taagcgtcag ctcttcttta gaaaaaaact gcttcactcg
     3481 tcccagatgc ttcgggcagt gtccttgggt caagaccgct ttagacgcca ttactgggtc
     3541 ttaccgtgtc ttgctggtat ctttgtggaa ggatcagagg ggagtgcagt tactgaagat
     3601 ggaataaagc aagaaaccga gtccttgatg gaagcagtca cttcaacgcc cagctctgcc
     3661 caagtctctg taaagaggga gccaacgggc tctaccacct ctacttctcc tgcccggtcc
     3721 cgagggcgac ctcgaaaacc taagccaggg tctctgcagc ctcagcacct taagtccacc
     3781 attagagaac atgattcaga acaagcccag tctcaagctc acccaagagc tcagcctcag
     3841 ccccagcctc agccccagcc tcagcctcag cctcagactc ctatccagcc tcatcttcag
     3901 tcaagtaacg ggttcctaga accggaaggt tcccctttct ctctgggtca gagccagcac
     3961 gacctcagcc agtctgcctt cctgtcttgg ctgagccaga ctcagagcca caactccctg
     4021 ttgagcagct cagtcctcac gcctgatagc agccccggaa aattagactc tgctccatct
     4081 cagtccttag aggagccaga gcctgatgag acacaaccct gccctggtcc tcaaggtccg
     4141 tggtttaact tctcagccca gataccctgt gatgctgctc ctacaccacc tcctgcagtg
     4201 tctgaggacc aacctactcc ctccctccag ctgcctgcct cctctaaacc aatgaataca
     4261 ccaggtgctg ccaatccttg ttctccagtg cagctttctt tcacccactt acctggaggg
     4321 ggccctaaga ggctatctgg ggactctgaa gaaataccac agagtcccac agggctggga
     4381 caaccaaaac ggagagggag acctcctagc aagttcttca agcaggtgga gcaacattac
     4441 ttaacccagc tgacagccca gcctatcccc cctgatatgt gctcaggctg gtggtggatc
     4501 cgagatcctg agacactgga tgtcctgctc aaggcgctgc atccccgagg catccgggag
     4561 aaggcgcttc acaaacatct tagtaagcac aaggactttt tgcaggaggt ttgtttgcag
     4621 cccttaactg accccatctt tgagcccagt cagctgcctg ccttggaaga aggaattatg
     4681 agttggtccc ccaaagagaa aactttcgag acagacctgg ctgtgcttca gtgggtggag
     4741 gagctagaac ggcgagtcgt cctctctgat ctgcagattc ggggctggac atgccctagt
     4801 ccagactcca ccagagaaga cttgacctac tgtgagcatc tgcctgactc tcaggaggac
     4861 atcccttgga ggggtcgggg cagggaagga gcagtgcctc agcggcagaa caccaaccct
     4921 ctggacctcg ctgtgatgcg attggctgtt ctggagcaaa acgtggagcg gcggtacttg
     4981 cgggagcctt tgtgggcagc tcacgaggtg gtagtggaga aggccctcct gagcacaccc
     5041 agtggtgagc ctgacagtgc cacgactgag atatcctatg agatcacgcc tcgggtccga
     5101 gtctggcggc agacacttga gaggtgccgc agtgcagccc aagtgtgcct gtgcgtgggc
     5161 cagctggaaa ggtccatcgc ctgggagaag tctgtcaaca aagtgacctg tctggtctgt
     5221 cggaagggtg acaatgacga gtttctcctg ctttgtgatg ggtgtgaccg aggctgccac
     5281 atttactgtc atcggcccaa gatggaggct gttccagaag gagactggtt ctgtgctgtc
     5341 tgtctggccc agcaggtaga ggaagaatac actcagaggc ctgcttctct aaaacgaggc
     5401 cagaagcgga aaagtagttt tccactgacc ttcacagaag gtgacagccg gcggcggcgg
     5461 cggcggcgaa ggatgttgtc aaggaataga gaaagcccag cagtgtctca gtacccagaa
     5521 gacaggctat ctccctccaa aagacggcga ctttcgatga gaagccacca cagtgatctc
     5581 acattttgcg agatcatcct aatggagatg gagtcccatg atgcagcctg gcctttccta
     5641 gaacctgtga acccccgctt ggtgagtggg taccggcgcg tcatcaagaa ccctatggac
     5701 ttttccacca tgcgagaacg gctgctccgg ggagggtaca ctagctcaga ggagtttgca
     5761 gctgatgccc tgctggtttt tgacaactgc cagaccttca atgaggatga ctctgaagtg
     5821 ggcaaggctg ggcacatcat gcgccgcttc tttgagagcc gctgggagga attttatcag
     5881 ggaaaacagg ccaatctatg aggcaaggaa ggtgggagtc accttgtggc atcttctcca
     5941 accttccaaa caaaaacctg ccgttctcac ctgctgatgg ctgccctggg tggactcaag
     6001 tcagacaatg ctgatttttg actgccctcg gcagcaccca catcctctcc ttcctaatcc
     6061 cttttctccc tcctcttgct cctcaaataa gagatgcaga gatgaggtcc ttctggacag
     6121 aaagccaaaa aagaaagaat tttcctgttt tttctccctg agttacaatg gagagaggca
     6181 aagaagccct ccctccttgt cctagcctcc tcccttccct ttccatgatg cctcagcttc
     6241 ctggggttat ttaacaatag caatagttct agtgaatgtg tgaaaccgag aaacactctg
     6301 tactgtgtgc ggacccgcag tgacggccag taaagtggac ttaactccca ggtgtgtcga
     6361 gccggacacc gggccctgaa catgctgctt ttgtctgtgt tgagtcctcc ctcctcctct
     6421 aactcctccc tatttgtagg gttttgtccc acccagtaat gtaagactgt cgtgtacggg
     6481 ttcttctttc cctccctttc cccaggcttt ttgcccttgt gtggaaaaca aagttcagag
     6541 ctcccctgtc tgtgtgtcct catcttctgc caataggtaa ccctctaagg tgtcggctcc
     6601 tcctcacacg ctgagtttct gtgagtctct agccttctct gaaattcagt gactggggag
     6661 cgggcagaca ggcagacacc cctaggcctt ccagcctcct tcccctgctt cccagacctc
     6721 cctcttggga gctcctcagg gacaacgact gctgagttcg agtgctcctc cgagatggag
     6781 gccaggcagc agtcaactgg cctcagagag gaggggagag gtagtgtgtg ttgtgagtgt
     6841 gagtgtgacc ctgtagtgtg atagacccat tgttccccca catgtgttta ttcccacctt
     6901 cccattgttt cttaccatca ctttttgtct ttgggaaaac acaggaacta ttttctctgg
     6961 ggcaaagctg gctctcctca tggtcatttc ttttccagcc tcttcaaact gtgcaatctt
     7021 ttcagcagga actccctctc ctcttactag ctttgaggtt tgtgtttttg ttgggagaac
     7081 tggatcttcc ctaaaccatg agtgtctggg tttagctgtg ttttccttcc gcacaccgtc
     7141 ttcatatccc aggacccctt ccttccccag cagcagagac cctggagcac aggatgggca
     7201 gagaggagga tctgggtcta ccactgccct gtgtgtgact aagcccaggt tagcccccag
     7261 catgagagga cagctgctaa ctccgagctg tagccatggg ccactggccc ctgctttcct
     7321 gctcagccaa gcccctccca tcagaaatta cgggtacttg cactggggag gtggctgctg
     7381 gctggcctaa gcagagagct gaggcatcca agcaatgttc gttccatggg tgggtggagg
     7441 atgccaggtg aggcgaagca ttccttgtac tccagcagta ctgaagagca gggcagtgca
     7501 gcccccactc ttctcaaccc accctcaccg cgctccctgt tgcctacttc taaagtcgcc
     7561 ttttctgtcg ataaacctca aaacttaatt ttatttgaga attttttttt gcttttaaat
     7621 aagaggtgga ttgaagaata tttgaattga ctttatatta tgcataaata tttatatttt
     7681 atctaaataa ctgcgctgta acaaactttg tgttagatgt ttggaactgt ttcccctggc
     7741 ataaagtgta ctggagtcat tcgttgttga ggtgagggac agtggagcct gggctctctg
     7801 ctgtgtgctc ctctcccagc cccgcctctg ccctagggac caggcactct gaaggtggag
     7861 gtcctagcct tgatttgaag aaatgggggc tgaagggatt gtggggcagg atgtgatcaa
     7921 aggggccatt tctcatactt ttctttcctc atcttcactg cccctcaagc taggtggact
     7981 tttctcttgt tgacaaagag tatttggtag ggaaagcagg ttaaaaataa aaagacagcc
     8041 ctccccctgc cctttgtgtc ccctccccag taacagcaag aaaccatcaa caccaacaag
     8101 tttccatgtt ccttttacaa caaaagggac tttttatata accaaatgtg gtgttttagt
     8161 gactttttga taatgtacag ttttttgtga atttaaattt atttctttct atatttttag
     8221 gaccaatctc atttttaata aggtttaaaa aaaggaaaaa agtctagaga aaaaaaaaaa
     8281 aaacaaaccc gggtttttgc catgtgatgt tccacaggtg cggctgtaga aagtgcttgt
     8341 cattgaataa agccacattt gataaaga
//
