LOCUS       NM_001106748             969 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus basic leucine zipper ATF-like transcription
            factor (Batf), mRNA.
ACCESSION   NM_001106748 XM_001057854 XM_216745
VERSION     NM_001106748.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 969)
  AUTHORS   Chen,L.Y., Fan,X.P., Fan,Y.C., Zhao,J., Gao,S., Li,F., Qi,Z.X. and
            Wang,K.
  TITLE     BATF Interference Blocks Th17 Cell Differentiation and Inflammatory
            Response in Hepatitis B Virus Transgenic Mice
  JOURNAL   Dig Dis Sci 64 (3), 773-780 (2019)
   PUBMED   30498928
  REMARK    GeneRIF: Hepatitis B virus markedly upregulated hepatic BATF
            expression and promoted Th17 cell activation.
REFERENCE   2  (bases 1 to 969)
  AUTHORS   He,L., Peng,X., Chen,Y., Liu,G., Liu,Z., Zhu,J., Liu,Y., Liu,H.,
            Liang,Y., Liu,F., Sun,L. and Peng,Y.
  TITLE     Regulation of IgA Class Switch Recombination in Immunoglobulin A
            Nephropathy: Retinoic Acid Signaling and BATF
  JOURNAL   Am J Nephrol 43 (3), 179-194 (2016)
   PUBMED   27073891
  REMARK    GeneRIF: upregulated in blood, spleen, and bone marrow in IgA
            nephropathy
REFERENCE   3  (bases 1 to 969)
  AUTHORS   Glasmacher,E., Agrawal,S., Chang,A.B., Murphy,T.L., Zeng,W., Vander
            Lugt,B., Khan,A.A., Ciofani,M., Spooner,C.J., Rutz,S., Hackney,J.,
            Nurieva,R., Escalante,C.R., Ouyang,W., Littman,D.R., Murphy,K.M.
            and Singh,H.
  TITLE     A genomic regulatory element that directs assembly and function of
            immune-specific AP-1-IRF complexes
  JOURNAL   Science 338 (6109), 975-980 (2012)
   PUBMED   22983707
REFERENCE   4  (bases 1 to 969)
  AUTHORS   Tussiwand,R., Lee,W.L., Murphy,T.L., Mashayekhi,M., KC,W.,
            Albring,J.C., Satpathy,A.T., Rotondo,J.A., Edelson,B.T.,
            Kretzer,N.M., Wu,X., Weiss,L.A., Glasmacher,E., Li,P., Liao,W.,
            Behnke,M., Lam,S.S., Aurthur,C.T., Leonard,W.J., Singh,H.,
            Stallings,C.L., Sibley,L.D., Schreiber,R.D. and Murphy,K.M.
  TITLE     Compensatory dendritic cell development mediated by BATF-IRF
            interactions
  JOURNAL   Nature 490 (7421), 502-507 (2012)
   PUBMED   22992524
REFERENCE   5  (bases 1 to 969)
  AUTHORS   Li,P., Spolski,R., Liao,W., Wang,L., Murphy,T.L., Murphy,K.M. and
            Leonard,W.J.
  TITLE     BATF-JUN is critical for IRF4-mediated transcription in T cells
  JOURNAL   Nature 490 (7421), 543-546 (2012)
   PUBMED   22992523
REFERENCE   6  (bases 1 to 969)
  AUTHORS   Wang,J., Sun,Q., Morita,Y., Jiang,H., Gross,A., Lechel,A.,
            Hildner,K., Guachalla,L.M., Gompf,A., Hartmann,D., Schambach,A.,
            Wuestefeld,T., Dauch,D., Schrezenmeier,H., Hofmann,W.K.,
            Nakauchi,H., Ju,Z., Kestler,H.A., Zender,L. and Rudolph,K.L.
  TITLE     A differentiation checkpoint limits hematopoietic stem cell
            self-renewal in response to DNA damage
  JOURNAL   Cell 148 (5), 1001-1014 (2012)
   PUBMED   22385964
  REMARK    Erratum:[Cell. 2014 Sep 11;158(6):1444]
REFERENCE   7  (bases 1 to 969)
  AUTHORS   Ise,W., Kohyama,M., Schraml,B.U., Zhang,T., Schwer,B., Basu,U.,
            Alt,F.W., Tang,J., Oltz,E.M., Murphy,T.L. and Murphy,K.M.
  TITLE     The transcription factor BATF controls the global regulators of
            class-switch recombination in both B cells and T cells
  JOURNAL   Nat Immunol 12 (6), 536-543 (2011)
   PUBMED   21572431
REFERENCE   8  (bases 1 to 969)
  AUTHORS   Betz,B.C., Jordan-Williams,K.L., Wang,C., Kang,S.G., Liao,J.,
            Logan,M.R., Kim,C.H. and Taparowsky,E.J.
  TITLE     Batf coordinates multiple aspects of B and T cell function required
            for normal antibody responses
  JOURNAL   J Exp Med 207 (5), 933-942 (2010)
   PUBMED   20421391
REFERENCE   9  (bases 1 to 969)
  AUTHORS   Schraml,B.U., Hildner,K., Ise,W., Lee,W.L., Smith,W.A., Solomon,B.,
            Sahota,G., Sim,J., Mukasa,R., Cemerski,S., Hatton,R.D.,
            Stormo,G.D., Weaver,C.T., Russell,J.H., Murphy,T.L. and Murphy,K.M.
  TITLE     The AP-1 transcription factor Batf controls T(H)17 differentiation
  JOURNAL   Nature 460 (7253), 405-409 (2009)
   PUBMED   19578362
REFERENCE   10 (bases 1 to 969)
  AUTHORS   Kuwamura,M., Maeda,M., Kuramoto,T., Kitada,K., Kanehara,T.,
            Moriyama,M., Nakane,Y., Yamate,J., Ushijima,T., Kotani,T. and
            Serikawa,T.
  TITLE     The myelin vacuolation (mv) rat with a null mutation in the
            attractin gene
  JOURNAL   Lab Invest 82 (10), 1279-1286 (2002)
   PUBMED   12379762
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473982.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001057854.1, XM_216745.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760396,
                              SAMEA5760400 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..969
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..969
                     /gene="Batf"
                     /gene_synonym="B-ATF"
                     /note="basic leucine zipper ATF-like transcription factor"
                     /db_xref="GeneID:299206"
                     /db_xref="RGD:1304923"
     exon            1..298
                     /gene="Batf"
                     /gene_synonym="B-ATF"
                     /inference="alignment:Splign:2.1.0"
     CDS             236..613
                     /gene="Batf"
                     /gene_synonym="B-ATF"
                     /note="B-cell-activating transcription factor; basic
                     leucine zipper transcription factor, ATF-like"
                     /codon_start=1
                     /product="basic leucine zipper transcriptional factor
                     ATF-like"
                     /protein_id="NP_001100218.1"
                     /db_xref="GeneID:299206"
                     /db_xref="RGD:1304923"
                     /translation="MPHSSDSSDSSFSRSPPPGKQDSSDDVRKVQRREKNRIAAQKSR
                     QRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLSSHEPLCSVLASGTPS
                     PPEVVYSAHAFHQPHISSPRFQP"
     exon            299..403
                     /gene="Batf"
                     /gene_synonym="B-ATF"
                     /inference="alignment:Splign:2.1.0"
     exon            404..969
                     /gene="Batf"
                     /gene_synonym="B-ATF"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctgtgcgc aagccccaaa gtgagcgaga tgtccctgtg gggagcagtc cctctgcacc
       61 ccagagagag gaggacgcag gggtctatcg gagatagctg caggacgagc aggggaggca
      121 cctgtggaag gtggtacgct gctggccccc tggcagtcaa gaaggggagc ttgctagtga
      181 gaagatcgcc cagaggcatc tgggacagtg tgggagagtc cggaagatta caaccatgcc
      241 tcacagctcc gacagcagcg actccagctt cagccgctct cctccccccg gcaagcagga
      301 ctcatccgat gatgtgagga aagttcagag gagagagaag aaccgcattg ctgcccagaa
      361 gagccgacag agacagacac agaaggccga cacccttcac ctggagagcg aggacctgga
      421 gaaacagaat gcggctcttc gaaaagagat caaacagctc acagaggagc taaagtactt
      481 cacatcggtg ctgagcagcc acgagcccct gtgctccgtg ctagccagtg gcaccccctc
      541 gccccccgag gtggtataca gcgcccatgc cttccaccag cctcacatca gctcaccacg
      601 cttccagccc tgagcttctg gatgagaaga gaacaaagcc atggtcgatg ctactcctgt
      661 gatcctatgg aggggccatg caaactgagg ccaggctgcc ctcatacctc tatccagagg
      721 cccagtgaca gaggcctgga caaatattga acacaaggac catagtggtc caagagacat
      781 gaggcatccc gggaaagtat agtcaatgta ctgaactctc ccggggaaat ctagcccatg
      841 tactggaccc agaaactgac gaaacaaccc tggagtgtca gtgtcgccaa ttatgcccaa
      901 gatgcaacgc acagagggag gagggcaggg gatgtagagt tttctaaata aatattttcc
      961 aagaaacaa
//
