LOCUS       NP_001299592            1150 aa            linear   ROD 01-APR-2024
DEFINITION  BAI1-associated protein 3 [Rattus norvegicus].
ACCESSION   NP_001299592
VERSION     NP_001299592.1
DBSOURCE    REFSEQ: accession NM_001312663.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1150)
  AUTHORS   Zhang,X., Jiang,S., Mitok,K.A., Li,L., Attie,A.D. and Martin,T.F.J.
  TITLE     BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of
            dense-core vesicles in neuroendocrine cells
  JOURNAL   J Cell Biol 216 (7), 2151-2166 (2017)
   PUBMED   28626000
  REMARK    GeneRIF: BAIAP3 functions indirectly in dense-core vesicle
            exocytosis by affecting DCV maturation through its role in DCV
            protein recycling.
REFERENCE   2  (residues 1 to 1150)
  AUTHORS   Wojcik,S.M., Tantra,M., Stepniak,B., Man,K.N., Muller-Ribbe,K.,
            Begemann,M., Ju,A., Papiol,S., Ronnenberg,A., Gurvich,A., Shin,Y.,
            Augustin,I., Brose,N. and Ehrenreich,H.
  TITLE     Genetic markers of a Munc13 protein family member, BAIAP3, are
            gender specifically associated with anxiety and benzodiazepine
            abuse in mice and humans
  JOURNAL   Mol Med 19 (1), 135-148 (2013)
   PUBMED   23698091
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1150)
  AUTHORS   Palmer,R.E., Lee,S.B., Wong,J.C., Reynolds,P.A., Zhang,H.,
            Truong,V., Oliner,J.D., Gerald,W.L. and Haber,D.A.
  TITLE     Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates
            regulated exocytosis in tumorigenesis
  JOURNAL   Cancer Cell 2 (6), 497-505 (2002)
   PUBMED   12498718
REFERENCE   4  (residues 1 to 1150)
  AUTHORS   Shiratsuchi,T., Oda,K., Nishimori,H., Suzuki,M., Takahashi,E.,
            Tokino,T. and Nakamura,Y.
  TITLE     Cloning and characterization of BAP3 (BAI-associated protein 3), a
            C2 domain-containing protein that interacts with BAI1
  JOURNAL   Biochem Biophys Res Commun 251 (1), 158-165 (1998)
   PUBMED   9790924
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.41800.1,
                                           SRR26643298.59355.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1150
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     Protein         1..1150
                     /product="BAI1-associated protein 3"
                     /calculated_mol_wt=128650
     Region          131..330
                     /region_name="C2A_Munc13-like"
                     /note="C2 domain first repeat in Munc13 (mammalian
                     uncoordinated)-like proteins; cd08676"
                     /db_xref="CDD:176058"
     Site            order(174,180,258,260)
                     /site_type="other"
                     /note="putative Ca2+ binding site [ion binding]"
                     /db_xref="CDD:176058"
     Region          973..1107
                     /region_name="C2B_Munc13-like"
                     /note="C2 domain second repeat in Munc13 (mammalian
                     uncoordinated)-like proteins; cd04009"
                     /db_xref="CDD:175976"
     Site            order(1004,1010,1068,1070,1076)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:175976"
     CDS             1..1150
                     /gene="Baiap3"
                     /coded_by="NM_001312663.1:108..3560"
                     /db_xref="GeneID:106146145"
                     /db_xref="RGD:10059729"
ORIGIN      
        1 mstlldikss vlrqvqvcps frrkteqepe itnsqepptg awkpgdgvef fahmrlilkk
       61 gdgrqglpcp evllrsgspa paepvdpnrg lraltqeeve mlyeealytv lhragtmgpd
      121 qvddeevlls ylqqvfgsss eehmeaimrv kkakaptyal kvsvmraknl lakdpngfsd
      181 pycmlgilpa ssapqessgq keqrfgfrkg skrssplpak ciqvtevkss tlnpvwkehf
      241 lleiedvntd qlhldiwdhd ddvslaeacr klneviglkg mtryfkqivk sarangtagp
      301 tedhtddflg clnipirevp vagadrwfkl eprssasrvq gdchlvlkli ttqrdtamsq
      361 rgrsgflsyl lllsrvlrfe hrveepnsss wrgelsgpgn tvlclhgaqs nlsplqlavl
      421 hwqvssrhhq trtldygyll glledvqahw eeaaslpqeq eesladsfsa fsefglrllr
      481 qlrdyfpatn stavyrlell lkcleklqlf qpafeicpfe telsmdiaaa lkrgnrewyd
      541 qllnakspre qpgpqrlagl veladiiyed lqscygvyas lfhgilkvdf ftltfrqler
      601 lvaeeawvlt eelspkmnle vasglfelyl tladtqrfws cipgresrsl alagihtpfl
      661 pavklwlqvl rdqakwrlqg avdvdtlepv daaskhsssa ataslclshi qelwvrlawp
      721 dpaqaqglgt qlsqdmceas lfytellrkk vdtqpgaage avseqlcvvl nnvelvrras
      781 gqalrglaws eganglegvl prpllssiqa ldedllreah tvtahltskm vadirkyvqh
      841 islspdsiqn deavapllky ldeklallnd slvkenlsrv lealwelllq ailqalsanr
      901 gvsadfygrf hftlealvsf fhaegqglpl enlrdgsykr leeelrlhkc strecieqfy
      961 ldklkqrsle qnrfgrltvr chyeaaeqrl avevlhaadl lpldanglsd pfvivelgpp
     1021 hlfplvrsqr tqvkartlhp vydelfhfsv paeacrrrga cvlftvmdhd wlstndfage
     1081 aalglggvsg iarphvgggv rpgqpitlhl rrpraqvrsa lrmlegrtnr eaqefvkklk
     1141 elekcmeadl
//
