LOCUS       NM_199270               1532 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus BRISC and BRCA1 A complex member 2 (Babam2),
            mRNA.
ACCESSION   NM_199270 XM_343022 XM_343023
VERSION     NM_199270.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1532)
  AUTHORS   Zheng,H., Gupta,V., Patterson-Fortin,J., Bhattacharya,S.,
            Katlinski,K., Wu,J., Varghese,B., Carbone,C.J., Aressy,B.,
            Fuchs,S.Y. and Greenberg,R.A.
  TITLE     A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates
            interferon responses
  JOURNAL   Cell Rep 5 (1), 180-193 (2013)
   PUBMED   24075985
REFERENCE   2  (bases 1 to 1532)
  AUTHORS   Cooper,E.M., Cutcliffe,C., Kristiansen,T.Z., Pandey,A.,
            Pickart,C.M. and Cohen,R.E.
  TITLE     K63-specific deubiquitination by two JAMM/MPN+ complexes:
            BRISC-associated Brcc36 and proteasomal Poh1
  JOURNAL   EMBO J 28 (6), 621-631 (2009)
   PUBMED   19214193
REFERENCE   3  (bases 1 to 1532)
  AUTHORS   Wang,B., Hurov,K., Hofmann,K. and Elledge,S.J.
  TITLE     NBA1, a new player in the Brca1 A complex, is required for DNA
            damage resistance and checkpoint control
  JOURNAL   Genes Dev 23 (6), 729-739 (2009)
   PUBMED   19261749
REFERENCE   4  (bases 1 to 1532)
  AUTHORS   Feng,L., Huang,J. and Chen,J.
  TITLE     MERIT40 facilitates BRCA1 localization and DNA damage repair
  JOURNAL   Genes Dev 23 (6), 719-728 (2009)
   PUBMED   19261748
REFERENCE   5  (bases 1 to 1532)
  AUTHORS   Shao,G., Patterson-Fortin,J., Messick,T.E., Feng,D., Shanbhag,N.,
            Wang,Y. and Greenberg,R.A.
  TITLE     MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to
            DNA double-strand breaks
  JOURNAL   Genes Dev 23 (6), 740-754 (2009)
   PUBMED   19261746
REFERENCE   6  (bases 1 to 1532)
  AUTHORS   Sobhian,B., Shao,G., Lilli,D.R., Culhane,A.C., Moreau,L.A., Xia,B.,
            Livingston,D.M. and Greenberg,R.A.
  TITLE     RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage
            sites
  JOURNAL   Science 316 (5828), 1198-1202 (2007)
   PUBMED   17525341
REFERENCE   7  (bases 1 to 1532)
  AUTHORS   Li,Q., Ching,A.K., Chan,B.C., Chow,S.K., Lim,P.L., Ho,T.C.,
            Ip,W.K., Wong,C.K., Lam,C.W., Lee,K.K., Chan,J.Y. and Chui,Y.L.
  TITLE     A death receptor-associated anti-apoptotic protein, BRE, inhibits
            mitochondrial apoptotic pathway
  JOURNAL   J Biol Chem 279 (50), 52106-52116 (2004)
   PUBMED   15465831
REFERENCE   8  (bases 1 to 1532)
  AUTHORS   Dong,Y., Hakimi,M.A., Chen,X., Kumaraswamy,E., Cooch,N.S.,
            Godwin,A.K. and Shiekhattar,R.
  TITLE     Regulation of BRCC, a holoenzyme complex containing BRCA1 and
            BRCA2, by a signalosome-like subunit and its role in DNA repair
  JOURNAL   Mol Cell 12 (5), 1087-1099 (2003)
   PUBMED   14636569
REFERENCE   9  (bases 1 to 1532)
  AUTHORS   Gu,C., Castellino,A., Chan,J.Y. and Chao,M.V.
  TITLE     BRE: a modulator of TNF-alpha action
  JOURNAL   FASEB J 12 (12), 1101-1108 (1998)
   PUBMED   9737713
REFERENCE   10 (bases 1 to 1532)
  AUTHORS   Li,L., Yoo,H., Becker,F.F., Ali-Osman,F. and Chan,J.Y.
  TITLE     Identification of a brain- and reproductive-organs-specific gene
            responsive to DNA damage and retinoic acid
  JOURNAL   Biochem Biophys Res Commun 206 (2), 764-774 (1995)
   PUBMED   7826398
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Nov 27, 2020 this sequence version replaced NM_199270.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061573.1, SRR26643293.34025.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                JAXUCZ010000006.1  30467289-30467341   c
            54-205              JAXUCZ010000006.1  30463407-30463558   c
            206-282             JAXUCZ010000006.1  30434771-30434847   c
            283-377             JAXUCZ010000006.1  30376923-30377017   c
            378-572             JAXUCZ010000006.1  30334689-30334883   c
            573-647             JAXUCZ010000006.1  30326002-30326076   c
            648-757             JAXUCZ010000006.1  30260358-30260467   c
            758-857             JAXUCZ010000006.1  30172345-30172444   c
            858-928             JAXUCZ010000006.1  30168959-30169029   c
            929-1011            JAXUCZ010000006.1  30160234-30160316   c
            1012-1165           JAXUCZ010000006.1  30115600-30115753   c
            1166-1532           JAXUCZ010000006.1  30089066-30089432   c
FEATURES             Location/Qualifiers
     source          1..1532
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     gene            1..1532
                     /gene="Babam2"
                     /note="BRISC and BRCA1 A complex member 2"
                     /db_xref="GeneID:362704"
                     /db_xref="RGD:735111"
     exon            1..53
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            54..205
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1229
                     /gene="Babam2"
                     /note="BRCA1-A complex subunit BRE; BRCA1/BRCA2-containing
                     complex subunit 45; brain and reproductive organ-expressed
                     protein; brain and reproductive organ-expressed (TNFRSF1A
                     modulator)"
                     /codon_start=1
                     /product="BRISC and BRCA1-A complex member 2"
                     /protein_id="NP_954891.1"
                     /db_xref="GeneID:362704"
                     /db_xref="RGD:735111"
                     /translation="MSPEIALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGC
                     TSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALHNL
                     ASWNPSNPECLLLVVKELVQQYHQFQCGRLRESSRLMFEYQTLLEEPQYGENMEIYAG
                     KKNNWTGEFSARFLLKLPVDFSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPK
                     LYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIA
                     AFLSHFGTGVVEYDAEGFTKLTLLLMWKEFCFLVHIDLPLFFPRDQPTLTFQSVYHFT
                     NSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFVPQFQEAAFANGKL"
     exon            206..282
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            283..377
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            378..572
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            573..647
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            648..757
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            758..857
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            858..928
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1011
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1165
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1532
                     /gene="Babam2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggtaacctg taccctgtct agtcgccggt tactgatcgg acttaagttc cagtggtaac
       61 tcataaatca agttaaaatg tctccagaaa ttgccttgaa ccgaatttct ccaatgctct
      121 ccccattcat atcgagcgtg gtccgaaatg ggaaggtggg actggatgct accaactgtt
      181 tgaggataac ggacttgaag tctggctgta catccttgac tcctggaccc aactgtgacc
      241 gcttcaaact gcacatcccg tacgctggag agacattaaa gtgggacata attttcaatg
      301 ctcagtaccc agagctgcct cctgatttca tctttggaga ggatgccgag ttcctgccag
      361 acccctctgc tctgcacaac cttgcctcct ggaacccttc gaaccccgag tgcctgctgc
      421 ttgtggtgaa ggagctggtg cagcagtacc accagtttca gtgcggccgc ctccgtgaga
      481 gctcacgcct catgtttgag taccagacgc tcctggaaga gcctcagtat ggagagaaca
      541 tggaaattta tgctgggaag aaaaacaact ggactggtga attttcagct cgttttctgt
      601 tgaagttacc agtagatttc agcaacattc ccacgtacct tctcaaggat gtaaacgaag
      661 atcccggaga agatgtggct ctcctttctg tcagctttga ggatactgaa gccacccagg
      721 tgtaccccaa gttgtacttg tcaccccgaa ttgagcatgc cctcgggggc tcctcggctc
      781 tccatatccc tgcttttcca ggaggaggat gtctcattga ttatgtgcct caagtgtgcc
      841 acctgctcac caacaaggtg cagtatgtga ttcaaggcta tcacaaaaga agagagtaca
      901 tcgctgcttt cctcagtcac tttggcacag gtgtcgtgga atatgatgca gaaggcttca
      961 caaaacttac actgctgctg atgtggaaag agttttgttt tcttgtacac attgacctgc
     1021 ctctgttttt ccctcgagat cagccaaccc tcacgtttca gtccgtctac cactttacca
     1081 acagtggaca gctttactcc caagcacaga aaaattaccc atacagcccc agatgggatg
     1141 gaaatgaaat ggccaagaga gcaaaggctt atttcaaaac ctttgtccct cagttccagg
     1201 aggctgcatt tgccaatgga aagctctagg aaacaccagt gttgagagac agccaaccag
     1261 actgctcagt ccacatgcgt gtcagcgctc aggctgcttc ctggaagccg cttggaatgt
     1321 cttcatggcg gccttttgct cacgcagcag ctctgcctgc tccacacagc cctgctctgc
     1381 tgcagcccaa acccgagctg gctggtagca ccctgagtcc tagcacctca ccgctggctg
     1441 ctcctcctcc ttccttaggt ttcttagctg aaagaaataa actgctttac gatggagaac
     1501 ttttccaggg aaataaaatg ttgtgaatgc gc
//
