LOCUS       NM_001006964            1368 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus BRISC and BRCA1 A complex member 1 (Babam1),
            mRNA.
ACCESSION   NM_001006964 XM_214301
VERSION     NM_001006964.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Rozenova,K., Jiang,J., Donaghy,R., Aressy,B., Greenberg,R.A. and
            Tong,W.
  TITLE     MERIT40 deficiency expands hematopoietic stem cell pools by
            regulating thrombopoietin receptor signaling
  JOURNAL   Blood 125 (11), 1730-1738 (2015)
   PUBMED   25636339
REFERENCE   2  (bases 1 to 1368)
  AUTHORS   Zheng,H., Gupta,V., Patterson-Fortin,J., Bhattacharya,S.,
            Katlinski,K., Wu,J., Varghese,B., Carbone,C.J., Aressy,B.,
            Fuchs,S.Y. and Greenberg,R.A.
  TITLE     A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates
            interferon responses
  JOURNAL   Cell Rep 5 (1), 180-193 (2013)
   PUBMED   24075985
REFERENCE   3  (bases 1 to 1368)
  AUTHORS   Cooper,E.M., Cutcliffe,C., Kristiansen,T.Z., Pandey,A.,
            Pickart,C.M. and Cohen,R.E.
  TITLE     K63-specific deubiquitination by two JAMM/MPN+ complexes:
            BRISC-associated Brcc36 and proteasomal Poh1
  JOURNAL   EMBO J 28 (6), 621-631 (2009)
   PUBMED   19214193
REFERENCE   4  (bases 1 to 1368)
  AUTHORS   Wang,B., Hurov,K., Hofmann,K. and Elledge,S.J.
  TITLE     NBA1, a new player in the Brca1 A complex, is required for DNA
            damage resistance and checkpoint control
  JOURNAL   Genes Dev 23 (6), 729-739 (2009)
   PUBMED   19261749
REFERENCE   5  (bases 1 to 1368)
  AUTHORS   Feng,L., Huang,J. and Chen,J.
  TITLE     MERIT40 facilitates BRCA1 localization and DNA damage repair
  JOURNAL   Genes Dev 23 (6), 719-728 (2009)
   PUBMED   19261748
REFERENCE   6  (bases 1 to 1368)
  AUTHORS   Shao,G., Patterson-Fortin,J., Messick,T.E., Feng,D., Shanbhag,N.,
            Wang,Y. and Greenberg,R.A.
  TITLE     MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to
            DNA double-strand breaks
  JOURNAL   Genes Dev 23 (6), 740-754 (2009)
   PUBMED   19261746
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083685.1.
            
            On Nov 22, 2004 this sequence version replaced XM_214301.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083685.1, FQ233705.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1368
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /note="BRISC and BRCA1 A complex member 1"
                     /db_xref="GeneID:290631"
                     /db_xref="RGD:1359516"
     exon            1..132
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     exon            133..482
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..1187
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /note="BRCA1-A complex subunit MERIT40; new component of
                     the BRCA1-A complex; mediator of RAP80 interactions and
                     targeting subunit of 40 kDa"
                     /codon_start=1
                     /product="BRISC and BRCA1-A complex member 1"
                     /protein_id="NP_001006965.1"
                     /db_xref="GeneID:290631"
                     /db_xref="RGD:1359516"
                     /translation="MEVAEANSPTEEEEEEEEEEGEEPISEPRPHTRSNPEGAEDRAI
                     GAQANVGSRSEGEGEAATADDGAASVPGAVPKPWQVPAPASEVQIRTPRVNCPEKVII
                     CLDLSEEMSVPKLESFNGSRTNALNVSQKMVEMFVRTKHKIDKSHEFALVVVNDDSAW
                     LSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYVVRT
                     ILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDIIYIHSGPEEKEDDMSWKDMFAFMGSL
                     DTKGTSYKYAVALAGPALELHNCVAKLLAHPLQRPCQSHASYSLLEEDEEAGEGEATV
                     "
     exon            483..541
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     exon            542..662
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     exon            663..741
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     exon            742..766
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     exon            767..896
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     exon            897..983
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1321
                     /gene="Babam1"
                     /gene_synonym="Merit40"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagatggc ggcttcctag agacctgatt gactggcccc ggtacccagg cagtggaacc
       61 tgcggcggtg tgaacgcgcg cgaactttgt gtcgccgcgg tctaacttcg actcggcttg
      121 ctgcagcttc aggcaggatc ctggcttcca ctatcccccc tccatccaac cactcgggaa
      181 ctatggaggt agccgaggcc aacagcccca ctgaggagga ggaagaggaa gaggaggaag
      241 aaggagagga gccgatttca gagcccaggc ctcacactcg ctccaatcct gagggggctg
      301 aggaccgggc catcggggct caggccaatg tgggtagccg cagcgagggc gaaggtgagg
      361 cagccactgc agatgatggg gcggccagtg tcccgggagc tgtgcccaag ccctggcagg
      421 taccagcacc agcatctgag gtccagattc gaacaccaag ggtcaactgt ccagagaaag
      481 tgatcatctg tctggatctt tcagaggaga tgtctgtgcc aaagctggag tcctttaatg
      541 ggtccagaac aaacgccctg aatgtgtctc agaagatggt tgagatgttt gtgcgcacga
      601 agcacaagat tgacaagagc cacgagtttg ccttggtcgt agtgaacgac gactctgcct
      661 ggttgtctgg cctgacctct gacccacgtg aactctgcag ctgcctgtac gacctagaga
      721 cggcatcctg ctccacattc aatttggaag gcctcttcag cctcatccag cagaagactg
      781 agctgccagt cacagagaat gtgcaaacca tcccaccccc ctacgtcgtg cgcaccatcc
      841 tggtctacag ccgcccaccc tgccagcccc agttctcctt gactgagccc atgaagaaga
      901 tgttccaatg tccctacttc ttcttcgaca tcatttacat ccacagtggc cctgaggaaa
      961 aggaagacga tatgagctgg aaggacatgt tcgccttcat gggcagtctg gacaccaagg
     1021 gcaccagcta caagtatgca gtagcacttg ctggccccgc cctggagctg cacaactgcg
     1081 tggccaagtt gctggcccac ccgctgcaga ggccctgcca gagccacgcg agctatagcc
     1141 tgctggaaga ggacgaagag gccggtgagg gggaggccac tgtgtgacaa ctccacaccg
     1201 tcccatgagg agagaaccca caccctcgtc actggcacat gctcaatctc acactgtcca
     1261 ctgtaaagtc attcttcctg ggaccatttt tgtcatcgga ataaaagtct gaggccccag
     1321 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
