LOCUS       NM_001106324            1980 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus beta-1,4-glucuronyltransferase 1 (B4gat1), mRNA.
ACCESSION   NM_001106324 XM_001072516 XM_219693
VERSION     NM_001106324.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y,
            Beltran Valero de Bernabe D, Yu L, Wright KM and Campbell KP.
  TITLE     The glucuronyltransferase B4GAT1 is required for initiation of
            LARGE-mediated alpha-dystroglycan functional glycosylation
  JOURNAL   Elife 3, e03941 (2014)
   PUBMED   25279699
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  AUTHORS   Praissman JL, Live DH, Wang S, Ramiah A, Chinoy ZS, Boons GJ,
            Moremen KW and Wells L.
  TITLE     B4GAT1 is the priming enzyme for the LARGE-dependent functional
            glycosylation of alpha-dystroglycan
  JOURNAL   Elife 3, e03943 (2014)
   PUBMED   25279697
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1980)
  AUTHORS   Wright KM, Lyon KA, Leung H, Leahy DJ, Ma L and Ginty DD.
  TITLE     Dystroglycan organizes axon guidance cue localization and axonal
            pathfinding
  JOURNAL   Neuron 76 (5), 931-944 (2012)
   PUBMED   23217742
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_219693.4, XM_001072516.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DY318138.1, FM043825.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1980
                     /gene="B4gat1"
                     /gene_synonym="B3gnt1"
                     /note="beta-1,4-glucuronyltransferase 1"
                     /db_xref="GeneID:293667"
                     /db_xref="RGD:1309541"
     exon            1..1142
                     /gene="B4gat1"
                     /gene_synonym="B3gnt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1334
                     /gene="B4gat1"
                     /gene_synonym="B3gnt1"
                     /EC_number="2.4.1.149"
                     /note="N-acetyllactosaminide
                     beta-1,3-N-acetylglucosaminyltransferase;
                     UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 1"
                     /codon_start=1
                     /product="beta-1,4-glucuronyltransferase 1"
                     /protein_id="NP_001099794.1"
                     /db_xref="GeneID:293667"
                     /db_xref="RGD:1309541"
                     /translation="MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQ
                     YFEFFPPSPRSVDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPNDVILATHAS
                     VDNLLHLSGLLERWEGPLSVSVFAATREEAQLATVLAYALSSHCPEMRARVAMHLVCP
                     SRYEAAVPDPREPGEFALLRSCQEVFDKLARVAQPGINYALGTNISYPNNLLRNLARE
                     EANYALVIDVDMVPSEGLWRSLREMLDQSNHWDGTALVVPAFEIRRARRMPMNKNELV
                     QLYQVGEVRPFYYGLCTPCHAPTNYSRWVNLPEESLLRPAYVVPWRDPWEPFYVAGGK
                     VPTFDERFRQYGFNRISQACELHMAGFNFEVLNEGFLVHKGFKEALKFHPQKEAENQR
                     NKILYRQFKQELKARYPNSPHRC"
     exon            1143..1980
                     /gene="B4gat1"
                     /gene_synonym="B3gnt1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggctgcg gtaaatccgg gcttgcggtg gctggcagag gttacggccc ggtggtctct
       61 gcttctcgcc gggatccccg agagccatgc aaatgtccta cgccatccga tgcgccttct
      121 accagctgct gctggccgcg ctcatgttgg tggcaatgct gcagctgctc tacctatcgc
      181 tgctctccgg tctgcacggc caggaggagc aagaacagta tttcgagttc ttcccgccgt
      241 ctccgcgatc cgtagaccag gtaaagtctc aactccgcac cgcactggcc tccggaggcg
      301 ttctggatgc cagcggcgat tatcgcgtct acaggggtct actgaagacc accatggacc
      361 ccaacgatgt catcttggcc acgcatgcca gcgtagacaa cctactgcac ctgtccggac
      421 ttctggagcg ctgggagggt ccgctgtccg tttcagtgtt cgcggccacc agagaagagg
      481 cgcagctggc cacggtgctg gcctacgcgc tgagcagcca ctgccccgag atgcgcgcca
      541 gggtcgccat gcacctcgtg tgcccctcgc gttatgaggc cgctgtgccc gacccccgag
      601 agcctgggga gtttgccctg ctgcggtcct gtcaagaggt ctttgacaag ctagccaggg
      661 tggcccaacc cgggattaat tatgcactgg ggaccaacat ctcctatccc aataacctgt
      721 taaggaatct ggctcgagaa gaagccaatt atgccctggt gatcgatgtg gacatggtgc
      781 ctagcgaagg gctgtggaga agcctaaggg aaatgttgga tcagagtaac cactgggatg
      841 gcacagccct ggtggtgcct gcgtttgaaa ttcgccgagc ccgccggatg ccgatgaaca
      901 agaacgagct agtacagctc tatcaggtgg gcgaagtccg gcccttctat tatgggctat
      961 gcacgccttg ccatgcgccc accaactact cccgctgggt caacctgcca gaagagagtt
     1021 tgctgagacc tgcctacgtg gtgccctgga gggacccctg ggaaccgttt tacgtggctg
     1081 gaggaaaggt gcccacattt gatgaacgct ttcggcagta tggtttcaat cgaatcagcc
     1141 aggcttgtga actgcacatg gcagggttta attttgaggt gctgaacgaa ggttttctgg
     1201 ttcataaggg attcaaggag gcattgaagt ttcaccccca aaaggaggct gaaaaccagc
     1261 gcaataagat tctttaccga caattcaaac aggagttgaa ggctaggtac cccaactctc
     1321 cccaccgatg ctgagttctt tccttccacg gtctgagaat tttcagcatc tggcgcttca
     1381 ggcctgactg gggtaagaac atgcctccac tttacagagg tagctgtggt tttggaacac
     1441 tggacttgac tatgaggtgc tgggagcaag tctcagcttt accactaact agtagggtgg
     1501 ccttgagcaa aacctgttcc ttctctgagc ctccattacc ccgtctgtaa aaagggaggt
     1561 gaaaatacct acctcacaga actgttggct cagatgagac gctgtatgtg aaaacatcct
     1621 gtaaacttcg tacaaatgtg aagtattaat attgctacag tgttattatt atgatattgt
     1681 tattattaac aatgttgggt ggatagcggc agagcaaaaa gtatgaatgg gctagagctt
     1741 gagtatttaa taaaatgagc cttttggaaa gatgaaaaca tagaacgtag tgctcagaac
     1801 tggcgtaaaa tgtaagcttc ctcgttctct tcatgcctgc gccctccacc ctccgagctc
     1861 caaggaggaa agggtctgta ggtcctgggg gttaaaagtc ccagctctgt gccctcctgg
     1921 aggtcgggct actcatttgc cttcggatga cagtgtgtaa ataaacgagt gttacaccca
//
