LOCUS       NM_001009539            2007 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus beta-1,4-galactosyltransferase 3 (B4galt3), mRNA.
ACCESSION   NM_001009539
VERSION     NM_001009539.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2007)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   2  (bases 1 to 2007)
  AUTHORS   Almeida,R., Amado,M., David,L., Levery,S.B., Holmes,E.H., Merkx,G.,
            van Kessel,A.G., Rygaard,E., Hassan,H., Bennett,E. and Clausen,H.
  TITLE     A family of human beta4-galactosyltransferases. Cloning and
            expression of two novel UDP-galactose:beta-n-acetylglucosamine
            beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3
  JOURNAL   J Biol Chem 272 (51), 31979-31991 (1997)
   PUBMED   9405390
  REMARK    Erratum:[J Biol Chem 1998 Jul 17;273(29):18674]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061812.1.
            
            [WARNING] On May 1, 2024 this sequence was replaced by
            NM_001009539.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061812.1, SRR8487230.123649.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2007
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..2007
                     /gene="B4galt3"
                     /note="beta-1,4-galactosyltransferase 3"
                     /db_xref="GeneID:494342"
                     /db_xref="RGD:1359221"
     exon            1..71
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
     exon            72..242
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
     exon            243..534
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
     CDS             276..1463
                     /gene="B4galt3"
                     /EC_number="2.4.1.90"
                     /EC_number="2.4.1.38"
                     /EC_number="2.4.1.275"
                     /note="b4Gal-T3; beta4Gal-T3; beta-1,4-GalTase 3;
                     UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase,
                     polypeptide 3; nal synthase; UDP-Gal:beta-GlcNAc
                     beta-1,4-galactosyltransferase 3;
                     UDP-galactose:beta-N-acetylglucosamine
                     beta-1,4-galactosyltransferase 3; N-acetyllactosamine
                     synthase; beta-N-acetylglucosaminylglycopeptide
                     beta-1,4-galactosyltransferase; neolactotriaosylceramide
                     beta-1,4-galactosyltransferase"
                     /codon_start=1
                     /product="beta-1,4-galactosyltransferase 3"
                     /protein_id="NP_001009539.1"
                     /db_xref="GeneID:494342"
                     /db_xref="RGD:1359221"
                     /translation="MLRRLLERPCTLALLVGSQLAVMMYLSLGGFRSLSALFGRDPGP
                     TFDYSHPHDVYSNLSHLPGAPGAAGAPLAQVLPDCPERSPFLVGPVSVSFSPVPSLAE
                     IVERNPRVESGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGI
                     YVIHQAGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRH
                     VAVAMNKFGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATRVRLAGM
                     KISRPPTSVGHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYRLLARELG
                     PLYTNITADIGTDPRGPRAPSGPRYPPGSSQAFRQEMLQRRPPARPGPLPTANHTAPH
                     GSH"
     exon            535..770
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
     exon            771..961
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1084
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1189
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1970
                     /gene="B4galt3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcttccaa gatggcggca gcgatgcttg cccggttgtc cgggtggcgg tgacgacggg
       61 aagcagacca ggtgactggt tatccttgat catttctggt tcccgctggt cccagattgg
      121 ctgttgggat gcttgttttc tgtcctctgt gacagttgaa atttgagata atgcctcatt
      181 tctctgctcc ccggggacct cctggagcct ccatgattcg gaaaaagaca gcttgagcac
      241 agtcccttca cttcttacct agccctcagg tcgagatgtt gcggaggctg ctggagaggc
      301 cctgcacact ggccctgctt gtgggctccc aactggcagt tatgatgtat ctgtcactag
      361 ggggcttccg aagtcttagt gccctgtttg gtcgagatcc aggcccaaca ttcgactatt
      421 ctcatcccca tgatgtctat agtaacctca gtcacctgcc tggagcccct ggagctgcag
      481 gggctcctct agctcaagtt ctgcctgact gtccagaaag atcgcctttc ttagtgggtc
      541 ctgtgtcagt atcctttagc ccagtgccat cactagcaga gatcgtggag cggaatcccc
      601 gggtggaatc agggggccgg taccgtcctg caggatgtga gcctcgctcc cgaacagcca
      661 taattgtgcc ccaccgtgcc cgggagcacc acctccgact gctactctat cacctgcacc
      721 ccttcctgca gcgccagcag cttgcttatg gcatctatgt catccaccag gctggaaatg
      781 gaacgtttaa cagggccaaa ctgctgaacg taggggtcag ggaagccctt cgtgacgaag
      841 agtgggactg cttgttttta cacgatgtgg acctccttcc agaaaacgac cataacctgt
      901 atgtgtgtga cccccgggga ccccgccatg ttgctgtcgc catgaacaag tttggataca
      961 gccttccgta cccccagtac tttggcggag tttcagcact cactcctgac cagtacctga
     1021 agatgaatgg cttccccaat gaatactggg gctggggtgg cgaggatgac gacattgcta
     1081 ccagggttcg cctggctggg atgaagattt cccgaccacc cacctctgtg ggacactaca
     1141 agatggtgaa gcacagaggg gataaaggaa atgaggaaaa cccccacaga tttgacctcc
     1201 tggtccgtac ccagaattct tggacacaag atggaatgaa ctcactaaca taccgactgc
     1261 tggcaagaga gctgggtcct ctctacacca acatcactgc agacattggg actgaccctc
     1321 ggggtccccg ggctccctct ggtccccgat acccaccagg ttcctcccag gccttccgtc
     1381 aggagatgct gcaacgccgg cccccagcta ggcctggccc tctgcctact gccaaccaca
     1441 cagctcccca tggttcacac tgactcttct ctgcccactg taatcatgaa actaaatggg
     1501 aggggtcgag ttcctcatac cctctgctcc tcactgcttt gagggatgtg agggacttta
     1561 ctgctgtgct agggggcagg gacctctcct cactactaga ttggagctgg gctcctctag
     1621 acctggaggt tcctctttct aggggccacc tgtcagggct tatgactgtg aatctttgat
     1681 gtcattttat gtgacaaatc ctgggagtcc tctgcccctg gggttaggag cagggctgga
     1741 tcccacgtcc cttcctcgtc tgtggacatt gctctttcaa gagtgatctg gcttctcctg
     1801 ggacctctgt gaatatttat tctatttatg atggttcctg agaagctgtc tggaagagga
     1861 aacccctagc taggcatttc ctgcgagtgc tggagtgact cctctggtct tgacccaggg
     1921 ggcaggggct gggattttga tatcttttct aataaaggac tttgtctcac aaaaaaaaaa
     1981 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
