LOCUS       NM_001128184            1574 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus beta-1,3-glucuronyltransferase 3 (B3gat3), mRNA.
ACCESSION   NM_001128184
VERSION     NM_001128184.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1574)
  AUTHORS   Budde BS, Mizumoto S, Kogawa R, Becker C, Altmuller J, Thiele H,
            Ruschendorf F, Toliat MR, Kaleschke G, Hammerle JM, Hohne W,
            Sugahara K, Nurnberg P and Kennerknecht I.
  TITLE     Skeletal dysplasia in a consanguineous clan from the island of
            Nias/Indonesia is caused by a novel mutation in B3GAT3
  JOURNAL   Hum Genet 134 (7), 691-704 (2015)
   PUBMED   25893793
REFERENCE   2  (bases 1 to 1574)
  AUTHORS   Koike T, Izumikawa T, Sato B and Kitagawa H.
  TITLE     Identification of phosphatase that dephosphorylates xylose in the
            glycosaminoglycan-protein linkage region of proteoglycans
  JOURNAL   J Biol Chem 289 (10), 6695-6708 (2014)
   PUBMED   24425863
REFERENCE   3  (bases 1 to 1574)
  AUTHORS   Baasanjav S, Al-Gazali L, Hashiguchi T, Mizumoto S, Fischer B, Horn
            D, Seelow D, Ali BR, Aziz SA, Langer R, Saleh AA, Becker C,
            Nurnberg G, Cantagrel V, Gleeson JG, Gomez D, Michel JB, Stricker
            S, Lindner TH, Nurnberg P, Sugahara K, Mundlos S and Hoffmann K.
  TITLE     Faulty initiation of proteoglycan synthesis causes cardiac and
            joint defects
  JOURNAL   Am J Hum Genet 89 (1), 15-27 (2011)
   PUBMED   21763480
REFERENCE   4  (bases 1 to 1574)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1574)
  AUTHORS   Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE and
            Yates JR.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   6  (bases 1 to 1574)
  AUTHORS   Venkatesan N, Barre L, Benani A, Netter P, Magdalou J,
            Fournel-Gigleux S and Ouzzine M.
  TITLE     Stimulation of proteoglycan synthesis by glucuronosyltransferase-I
            gene delivery: a strategy to promote cartilage repair
  JOURNAL   Proc Natl Acad Sci U S A 101 (52), 18087-18092 (2004)
   PUBMED   15601778
  REMARK    GeneRIF: GlcAT-I has a role in controlling and reversing articular
            cartilage defects
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168710.1, SRR8487227.59659.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1574
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1574
                     /gene="B3gat3"
                     /note="beta-1,3-glucuronyltransferase 3"
                     /db_xref="GeneID:293722"
                     /db_xref="RGD:1311968"
     exon            1..260
                     /gene="B3gat3"
                     /inference="alignment:Splign:2.1.0"
     exon            261..435
                     /gene="B3gat3"
                     /inference="alignment:Splign:2.1.0"
     exon            436..796
                     /gene="B3gat3"
                     /inference="alignment:Splign:2.1.0"
     exon            797..1087
                     /gene="B3gat3"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1574
                     /gene="B3gat3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccggaagtg gtccttggtg tcgctcagag tccggtgttc ccaggaacta ttaagggagc
       61 ctggggaagg cggggcgcgg gcggggcggc cggggcgggg ccggcgggag ggccgagggc
      121 cggacggacc tgtccctgcc ggtccccggt ggaccccgcc tgccccggcg gcacggccat
      181 gaagctgaag ctgaaaaacg tgtttcttgc ctacttcctg gtgtcgatcg ccggcctcct
      241 ctacgctctg gtgcagctcg gccaaccttg tgactgcctc cctccacttc gagctgcagc
      301 tgagcagctc cggcaaaagg acctgaggat atcccagctg caagccgacc tccgtcgccc
      361 accccctgcc ccagcccagc ccccagaacc tgaggccctg cctactatct atgtcattac
      421 ccccacctat gccaggctag tacagaaggc agagctggtt cggctgtccc agaccctgag
      481 cttggtgccc cgtctacact ggctgctggt ggaggatgct gagagcccta ccccgctggt
      541 ctcggggctg ttggctgcct ctggtctcct cttcacacac ctggctgtcc ttacccccaa
      601 ggctcagcgg cttagggaag gtgagccagg ctgggtccgg ccccgaggag tagaacagcg
      661 caacaaagcc ctggactggc tcagaggaaa agggggtgct gtagggggag agaaggactc
      721 accaccacca ggcacccaag gagtcgtgta ttttgctgac gatgataaca cctacagccg
      781 ggagctcttt aaggagatgc gttggactcg tggtgtctca gtgtggcctg tggggctggt
      841 gggcggcctg cgatttgagg gccctcgggt acaggatggc cgtgttgtgg gtttccacac
      901 agcatgggaa cccaacaggc cctttcccct ggacatggca ggatttgcag tttccctgcc
      961 cttgctgctg gctaagccta atgcccagtt tgatgctact gcaccccggg gccacctgga
     1021 aagtagtctc ctgagccatc ttgtagatcc caaggacctg gagccccggg ctgccaactg
     1081 tactcaggta ctggtgtggc atacccggac agagaaaccg aagatgaagc aggaggaaca
     1141 gctacagcga cagggccagg ggtcagaccc agctattgag gtgtgatggc aatctcaccc
     1201 tgacttctac cttattttag gcacatacct tgtgggactg ggctccaggc cagcccagga
     1261 tgtggctttt ttttttttta agacctgatc cctcagaacc agaggcagcc cctccaacca
     1321 cagggtgtgg cccagttgct tctctgcctt cttccagcct gccatgtggc actgcccaca
     1381 ggctggggac aagcagcttc tgtagtgagc caggtcagcc ccatctgggg tggagcagga
     1441 cagatggact caggagggag ggtaacttat tggggacaag catgcagtgg ggggctagag
     1501 gagctgggct ggaccctccc cacctgagca tgctgatccc cttcctacct ctagaataaa
     1561 gaatctcaac ccag
//
